CU20130019A7 - Hormona foliculoestimulante humana recombinante, composición farmacéutica que la comprende - Google Patents
Hormona foliculoestimulante humana recombinante, composición farmacéutica que la comprendeInfo
- Publication number
- CU20130019A7 CU20130019A7 CU2013000019A CU20130019A CU20130019A7 CU 20130019 A7 CU20130019 A7 CU 20130019A7 CU 2013000019 A CU2013000019 A CU 2013000019A CU 20130019 A CU20130019 A CU 20130019A CU 20130019 A7 CU20130019 A7 CU 20130019A7
- Authority
- CU
- Cuba
- Prior art keywords
- fsh
- foliculating
- understands
- hormone
- pharmaceutical composition
- Prior art date
Links
- 229940088597 hormone Drugs 0.000 title 1
- 239000005556 hormone Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 abstract 2
- 230000011496 cAMP-mediated signaling Effects 0.000 abstract 1
- 210000004978 chinese hamster ovary cell Anatomy 0.000 abstract 1
- 208000000509 infertility Diseases 0.000 abstract 1
- 230000036512 infertility Effects 0.000 abstract 1
- 231100000535 infertility Toxicity 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
- 230000002485 urinary effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pregnancy & Childbirth (AREA)
- General Chemical & Material Sciences (AREA)
- Gynecology & Obstetrics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Preparaciones que comprenden una FSH mejorada que puede estimular la liberación de esteroides sexuales en una concentración mucho menor que la FSH de uso habitual, que es una FSH urinaria o una FSH recombinante que se obtiene de células CHO, y que actúa de manera independiente de la señalización del AMPc. Estas preparaciones que comprenden una FSH mejorada pueden usarse en el tratamiento de la infertilidad.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2010/004769 WO2012016576A1 (en) | 2010-08-04 | 2010-08-04 | Improved recombinant human follicle-stimulating hormone |
| PCT/EP2011/063492 WO2012017058A1 (en) | 2010-08-04 | 2011-08-04 | Improved recombinant human follicle-stimulating hormone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CU20130019A7 true CU20130019A7 (es) | 2013-05-31 |
| CU24043B1 CU24043B1 (es) | 2014-11-27 |
Family
ID=43242604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU2013000019A CU24043B1 (es) | 2010-08-04 | 2013-02-04 | Hormona foliculoestimulante humana recombinante, composición farmacéutica que la comprende |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US9527899B2 (es) |
| EP (2) | EP2601210B1 (es) |
| JP (2) | JP6001534B2 (es) |
| KR (1) | KR20130136448A (es) |
| CN (2) | CN106146646A (es) |
| AR (1) | AR082852A1 (es) |
| AU (1) | AU2011287525B2 (es) |
| BR (1) | BR112013004051A2 (es) |
| CA (1) | CA2805134C (es) |
| CU (1) | CU24043B1 (es) |
| CY (1) | CY1117778T1 (es) |
| DK (1) | DK2601210T3 (es) |
| EA (1) | EA029955B1 (es) |
| ES (2) | ES2576868T3 (es) |
| HR (1) | HRP20160671T1 (es) |
| HU (1) | HUE028357T2 (es) |
| IL (1) | IL223867B (es) |
| MX (1) | MX336489B (es) |
| NZ (1) | NZ604877A (es) |
| PL (1) | PL2601210T3 (es) |
| PT (1) | PT2601210T (es) |
| RS (1) | RS54905B1 (es) |
| SG (1) | SG186755A1 (es) |
| SI (1) | SI2601210T1 (es) |
| SM (1) | SMT201600219B (es) |
| WO (2) | WO2012016576A1 (es) |
| ZA (1) | ZA201209436B (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI488640B (zh) * | 2008-04-16 | 2015-06-21 | Ferring Int Ct Sa | 藥學製劑 |
| WO2012016576A1 (en) | 2010-08-04 | 2012-02-09 | Glycotope Gmbh | Improved recombinant human follicle-stimulating hormone |
| WO2012168680A1 (en) | 2011-06-06 | 2012-12-13 | Ferring B.V. | Pharmaceutical preparation comprising recombinant fsh |
| JO3092B1 (ar) * | 2011-08-08 | 2017-03-15 | Ferring Bv | مركب لتحفيز مسيطر عليه للمبيض |
| NZ707016A (en) * | 2012-07-30 | 2017-08-25 | Trophogen Inc | Glycoprotein hormone long-acting superagonists |
| CN104543416B (zh) * | 2013-10-09 | 2018-06-19 | 中国科学院大连化学物理研究所 | 一种调节雌性动物繁殖性能的功能性单糖饲料及其应用 |
| CN103740754B (zh) * | 2013-10-25 | 2015-06-24 | 中国食品药品检定研究院 | 含有鼠神经生长因子的表达载体及细胞 |
| SG11201608132UA (en) | 2014-04-18 | 2016-11-29 | Glycotope Gmbh | Controlled ovarian hyperstimulation with improved recombinant human follicle-stimulating hormone |
| EP3091033A1 (en) * | 2015-05-06 | 2016-11-09 | Gamamabs Pharma | Anti-human-her3 antibodies and uses thereof |
| AR105669A1 (es) * | 2015-08-10 | 2017-10-25 | Glycotope Gmbh | Factor vii recombinante mejorado |
| US20180264086A1 (en) * | 2015-09-17 | 2018-09-20 | Glycotope Gmbh | Mammalian follicle-stimulating hormone composition with increased stability |
| CN106053861A (zh) * | 2016-07-28 | 2016-10-26 | 高常青 | 一种卵泡刺激素生物活性强度检测方法 |
| CA3160345A1 (en) * | 2019-11-06 | 2021-05-14 | The Regents Of The University Of Colorado, A Body Corporate | Modified follicle-stimulating hormone and methods of using the same |
| CN116063490A (zh) * | 2021-09-07 | 2023-05-05 | 苏州晟济药业有限公司 | 一种vhh抗体或其抗原片段的突变体及其用途 |
| EP4519296A1 (en) * | 2022-05-06 | 2025-03-12 | The Regents of the University of Colorado, a body corporate | Modified follicle-stimulating hormone and methods of using the same |
| IT202200023031A1 (it) * | 2022-11-08 | 2024-05-08 | Oncogreen Therapeutics S A | Composto ad effetto anti-metastatico |
| IT202200023037A1 (it) * | 2022-11-08 | 2024-05-08 | Oncogreen Therapeutics S A | Composti per l’uso nella riprogrammazione dei macrofagi |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1176976T2 (sl) | 1999-05-07 | 2015-12-31 | Merck Serono Sa | Uporaba LH, dajanega v srednji ali pozni folikularni fazi, za zdravljenje anovulatornih žensk |
| MEP38608A (en) * | 2001-10-22 | 2011-02-10 | Merck Serono Sa | Gonadotrophins for folliculogenesis |
| EP1725673A1 (en) * | 2004-02-13 | 2006-11-29 | Glycotope Gmbh | Sialytated glycoproteins-process conditions and an efficient method for their production |
| ES2620261T3 (es) * | 2006-09-10 | 2017-06-28 | Glycotope Gmbh | Uso de células humanas de origen leucémico mieloide para expresión de anticuerpos |
| GB2459641B (en) * | 2008-04-16 | 2012-06-27 | Ubiquisys Ltd | Basestation power control |
| TWI488640B (zh) * | 2008-04-16 | 2015-06-21 | Ferring Int Ct Sa | 藥學製劑 |
| EP2325194A1 (en) | 2009-11-24 | 2011-05-25 | Glycotope GmbH | Process for the purification of glycoproteins |
| WO2012016576A1 (en) * | 2010-08-04 | 2012-02-09 | Glycotope Gmbh | Improved recombinant human follicle-stimulating hormone |
-
2010
- 2010-08-04 WO PCT/EP2010/004769 patent/WO2012016576A1/en not_active Ceased
-
2011
- 2011-08-04 EA EA201390194A patent/EA029955B1/ru not_active IP Right Cessation
- 2011-08-04 DK DK11757190.1T patent/DK2601210T3/en active
- 2011-08-04 ES ES11757190.1T patent/ES2576868T3/es active Active
- 2011-08-04 SI SI201130854A patent/SI2601210T1/sl unknown
- 2011-08-04 MX MX2013000500A patent/MX336489B/es unknown
- 2011-08-04 BR BR112013004051A patent/BR112013004051A2/pt not_active Application Discontinuation
- 2011-08-04 PT PT117571901T patent/PT2601210T/pt unknown
- 2011-08-04 EP EP11757190.1A patent/EP2601210B1/en not_active Revoked
- 2011-08-04 WO PCT/EP2011/063492 patent/WO2012017058A1/en not_active Ceased
- 2011-08-04 AR ARP110102828A patent/AR082852A1/es unknown
- 2011-08-04 CN CN201610363950.XA patent/CN106146646A/zh active Pending
- 2011-08-04 SG SG2012093191A patent/SG186755A1/en unknown
- 2011-08-04 CA CA2805134A patent/CA2805134C/en not_active Expired - Fee Related
- 2011-08-04 HR HRP20160671TT patent/HRP20160671T1/hr unknown
- 2011-08-04 RS RS20160459A patent/RS54905B1/sr unknown
- 2011-08-04 PL PL11757190.1T patent/PL2601210T3/pl unknown
- 2011-08-04 US US13/814,059 patent/US9527899B2/en not_active Expired - Fee Related
- 2011-08-04 NZ NZ604877A patent/NZ604877A/en not_active IP Right Cessation
- 2011-08-04 ES ES16168841T patent/ES2764083T3/es active Active
- 2011-08-04 JP JP2013522259A patent/JP6001534B2/ja not_active Expired - Fee Related
- 2011-08-04 HU HUE11757190A patent/HUE028357T2/en unknown
- 2011-08-04 KR KR1020137005553A patent/KR20130136448A/ko not_active Ceased
- 2011-08-04 CN CN201180037096.3A patent/CN103068839B/zh active Active
- 2011-08-04 EP EP16168841.1A patent/EP3075744B1/en not_active Revoked
- 2011-08-04 AU AU2011287525A patent/AU2011287525B2/en not_active Ceased
-
2012
- 2012-12-12 ZA ZA2012/09436A patent/ZA201209436B/en unknown
- 2012-12-25 IL IL223867A patent/IL223867B/en active IP Right Grant
-
2013
- 2013-02-04 CU CU2013000019A patent/CU24043B1/es active IP Right Grant
-
2016
- 2016-06-16 CY CY20161100539T patent/CY1117778T1/el unknown
- 2016-06-24 JP JP2016125181A patent/JP2016168055A/ja not_active Withdrawn
- 2016-07-06 SM SM201600219T patent/SMT201600219B/it unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CU20130019A7 (es) | Hormona foliculoestimulante humana recombinante, composición farmacéutica que la comprende | |
| EA201170940A1 (ru) | Лечение рака с использованием комбинации бендамустина и анти-cd20-антитела | |
| CL2012002037A1 (es) | Uso de agonista doble del glucagon-glp-1 como agente inotropico en el tratamiento de la cardiopatía o la disfuncion cardiaca | |
| BR112013032717A2 (pt) | coagonistas do receptor de glucagon/glp-1 | |
| CL2013000018A1 (es) | Compuestos derivados de indolizina , su procedimiento de preparacion; composicion farmaceutica; y uso en el tratamiento del cancer, entre otros. | |
| CL2009000200A1 (es) | Compuestos derivados de 2,7-naftiridinas-1-ona, mediadores de syk; composicion farmaceutica; y uso en el tratamiento de una enfermedad inflamatoria, respiratoria, proliferativa celular o autoinmune. | |
| CR20120026A (es) | Construcciones novedosas de proteína del virus de papiloma humano (hpv) y su uso en la prevención de la enfermedad por el hpv | |
| MX2015000990A (es) | Analogos del glucagon. | |
| UY32926A (es) | Compuestos como antagonistas de los receptores de ácido lisofosfatídico | |
| CL2009000393A1 (es) | Composición farmaceutica que comprende a) un agente farmaceutico activable, b) un agente activo plasmonico; util para el tratamiento de trastornos de proliferación celular. | |
| PE20150200A1 (es) | Formulacion de anticuerpos | |
| NI201000044A (es) | Bromhidrato de bupropión y aplicaciones terapéuticas | |
| MA32568B1 (fr) | Formulations pharmaceutiques contenant des ligands de recepteur de dopamine | |
| EA201690964A1 (ru) | Композиции и способы для уменьшения серьезных неблагоприятных сердечно-сосудистых явлений | |
| MX2020005235A (es) | Celula humana transformada y uso de la misma. | |
| MX2024004652A (es) | Pautas posologicas para la movilizacion de celulas madre y progenitoras hematopoyeticas. | |
| CL2012001757A1 (es) | Compuestos derivados de 8-hidroxiquinolina-7-carboxamida; composicion farmaceutica; y su uso en el tratamiento de infecciones micoticas. | |
| MX382823B (es) | Antagonistas a2a como mejoradores de la función cognitiva y motora | |
| MX2018002921A (es) | Composicion de hormona foliculo-estimulante mamifera con estabilidad incrementada. | |
| CO6531459A2 (es) | Uso de 4-[etil(dimetil)amonio] butanoato en el tratamiento de enfermedades cardiovasculares | |
| CL2009001006A1 (es) | Compuestos derivados del acido 4-dimetil-aminobutirico; proceso de obtencion; composicion farmaceutica; y uso en el tratamiento o profilaxis de enfermedades tales como hiperglucemia, diabetes e hipertension entre otras. | |
| CL2010001594A1 (es) | Uso de nifurtimox para preparar un medicamento útil en el tratamiento de enfermedades causadas por trichomonadida. | |
| CL2009000878A1 (es) | Compuestos derivados de sulfonamida; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como dolor, migraña, diabetes, enfermedades del tracto respiratorio, enfermedades intestinales inflamatorias, obesidad, entre otras. | |
| EA201000864A1 (ru) | Фенилоксетанильные производные | |
| CL2008001322A1 (es) | Compuestos derivados de triazolil-aminopirimidina, sustituida con heterociclos; composicion farmaceutica; y uso en el tratamiento del cancer. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant of patent |