ATE277917T1 - Alkylaminobenzothiazole und -benzoxazole derivate - Google Patents

Alkylaminobenzothiazole und -benzoxazole derivate

Info

Publication number: ATE277917T1
Authority: AT; Austria
Prior art keywords: alkylaminobenzothiazoles; benzoxazoles; derivatives; benzoxazoles derivatives
Prior art date: 1996-05-10

Application number

AT97923913T

Other languages

English (en)

Inventor

Ludo Edmond Josephine Kennis

Josephus Carolus Mertens

Serge Maria Aloysius Pieters

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-05-10

Filing date

1997-05-02

Publication date

2004-10-15

1997-05-02 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2004-10-15 Application granted granted Critical

2004-10-15 Publication of ATE277917T1 publication Critical patent/ATE277917T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Thiazole And Isothizaole Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT97923913T 1996-05-10 1997-05-02 Alkylaminobenzothiazole und -benzoxazole derivate ATE277917T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP96201282		1996-05-10
PCT/EP1997/002505 WO1997043271A1 (en)	1996-05-10	1997-05-02	Alkylaminobenzothiazole and -benzoxazole derivatives

Publications (1)

Publication Number	Publication Date
ATE277917T1 true ATE277917T1 (de)	2004-10-15

Family

ID=8223970

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT97923913T ATE277917T1 (de)	1996-05-10	1997-05-02	Alkylaminobenzothiazole und -benzoxazole derivate
AT03075959T ATE350373T1 (de)	1996-05-10	1997-05-02	Radiomarkierte alkylamino-benzothiazole und - benzothiazole sowie ihre verwendung als d4- liganden

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT03075959T ATE350373T1 (de)	1996-05-10	1997-05-02	Radiomarkierte alkylamino-benzothiazole und - benzothiazole sowie ihre verwendung als d4- liganden

Country Status (28)

Country	Link
US (2)	US6103725A (de)
EP (2)	EP0912533B1 (de)
JP (1)	JP3237759B2 (de)
KR (1)	KR100330699B1 (de)
CN (1)	CN1074766C (de)
AR (1)	AR007079A1 (de)
AT (2)	ATE277917T1 (de)
AU (1)	AU710175B2 (de)
BG (1)	BG64097B1 (de)
BR (1)	BR9709065A (de)
CA (1)	CA2253453C (de)
CZ (1)	CZ295639B6 (de)
DE (2)	DE69730962T2 (de)
EA (1)	EA001360B1 (de)
EE (1)	EE03563B1 (de)
ES (2)	ES2279923T3 (de)
HU (1)	HUP9902993A3 (de)
ID (1)	ID16889A (de)
IL (1)	IL126968A0 (de)
MY (1)	MY117852A (de)
NO (1)	NO311027B1 (de)
NZ (1)	NZ332309A (de)
PL (1)	PL190721B1 (de)
SK (1)	SK282919B6 (de)
TR (1)	TR199802253T2 (de)
TW (1)	TW593290B (de)
WO (1)	WO1997043271A1 (de)
ZA (1)	ZA974053B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1293804B1 (it)	1997-08-01	1999-03-10	Recordati Chem Pharm	Diarilalchilpiperazine attive sulle basse vie urinarie
US6281216B1 (en) *	1998-02-09	2001-08-28	Duphar International Research B.V.	2-aminoquinoline derivatives having d4-agonistic activity
EP0982030A3 (de) *	1998-08-17	2000-05-10	Pfizer Products Inc.	2,7-substituierte Octahydropyrrolo(1,2-a)pyrazinderivate als 5ht 1a Liganden
HK1038749A1 (zh) *	1998-09-30	2002-03-28	纽罗根公司	2-哌嗪烷基氨苯并吡咯衍生物:多巴胺受体亚型特异配体
US6284759B1 (en)	1998-09-30	2001-09-04	Neurogen Corporation	2-piperazinoalkylaminobenzo-azole derivatives: dopamine receptor subtype specific ligands
US6107313A (en) *	1998-10-02	2000-08-22	Combichem, Inc.	Dopamine receptor antagonists
WO2001000604A1 (fr) *	1999-06-30	2001-01-04	Santen Pharmaceutical Co., Ltd.	Ligand de liaison avec le recepteur sigma-1 du cerveau
AU2001251083A1 (en) *	2000-03-31	2001-10-15	Ortho-Mcneil Pharmaceutical, Inc.	Method for using 2-aryloxyalkylaminobenzoxazoles and 2-aryloxyalkylaminobenzothiazoles as h3 antagonists
DE60128211T2 (de)	2000-03-31	2008-01-10	Ortho-Mcneil Pharmaceutical, Inc.	Phenyl-substituierte imidazopyridine
GB0203299D0 (en) *	2002-02-12	2002-03-27	Glaxo Group Ltd	Novel compounds
BR0314059A (pt)	2002-09-06	2005-07-05	Janssen Pharmaceutica Nv	Compostos heterocìclicos
US8257680B1 (en)	2004-02-24	2012-09-04	The General Hospital Corporation	Catalytic radiofluorination
US9017724B2 (en)	2004-02-24	2015-04-28	The General Hospital Corporation	Catalytic radiofluorination
EP1725269B1 (de) *	2004-02-24	2012-12-26	The General Hospital Corporation	Katalytische radiofluorierung
FR2877005A1 (fr) *	2004-10-22	2006-04-28	Bioprojet Soc Civ Ile	Nouveaux derives d'arylpiperazine
US7731940B2 (en)	2006-01-25	2010-06-08	The Regents Of The University Of California	Compositions and methods related to serotonin 5-HT1A receptors
CN102046638B (zh)	2008-03-21	2015-06-03	综合医院公司	检测和治疗阿尔茨海默病和相关疾病的化合物和组合物
JP2019528301A (ja) *	2016-08-26	2019-10-10	ブリストル−マイヤーズスクイブカンパニーＢｒｉｓｔｏｌ−ＭｙｅｒｓＳｑｕｉｂｂＣｏｍｐａｎｙ	インドールアミン２，３−ジオキシゲナーゼの阻害剤およびその使用方法
PT109740B (pt) *	2016-11-14	2020-07-30	Hovione Farmaciencia Sa	Processo para a preparação de brometo de umeclidínio
KR102823891B1 (ko) *	2020-01-14	2025-06-20	서울대학교산학협력단	혈관생성 저해 효과를 가지는 n-페닐벤조티아졸-2-아민 화합물 및 그를 포함하는 약제학적 조성물
CN116730948A (zh) *	2022-03-02	2023-09-12	圣奥化学科技有限公司	一种合成n-环己基-2-苯并噻唑的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU564702B2 (en) *	1984-05-22	1987-08-20	Sumitomo Chemical Company, Limited	Novel radioactive iodospiroperidol and process for its preparation
JPS63290858A (ja) *	1987-04-08	1988-11-28	サルター・インコーポレーテツド	アミロイド症及びアルツハイマー病の診断分析法及びそのための試薬
US4929618A (en) *	1988-03-25	1990-05-29	Ube Industries, Ltd.	Piperdine and piperazine derivatives, and antihistaminic pharmaceutical compositions containing the same
FR2656609B1 (fr) *	1989-12-28	1992-03-27	Synthelabo	Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.
US5731438A (en) *	1996-08-01	1998-03-24	Isis Pharmaceuticals, Inc.	N-(aminoalkyl)-and/or N-(amidoalkyl)-dinitrogen heterocycles

1997
- 1997-05-01 TW TW086105767A patent/TW593290B/zh not_active IP Right Cessation
- 1997-05-02 US US09/180,369 patent/US6103725A/en not_active Expired - Lifetime
- 1997-05-02 SK SK1532-98A patent/SK282919B6/sk not_active IP Right Cessation
- 1997-05-02 KR KR1019980707914A patent/KR100330699B1/ko not_active Expired - Fee Related
- 1997-05-02 EP EP97923913A patent/EP0912533B1/de not_active Expired - Lifetime
- 1997-05-02 PL PL97329849A patent/PL190721B1/pl not_active IP Right Cessation
- 1997-05-02 TR TR1998/02253T patent/TR199802253T2/xx unknown
- 1997-05-02 AT AT97923913T patent/ATE277917T1/de not_active IP Right Cessation
- 1997-05-02 DE DE69730962T patent/DE69730962T2/de not_active Expired - Lifetime
- 1997-05-02 JP JP54053597A patent/JP3237759B2/ja not_active Expired - Lifetime
- 1997-05-02 IL IL12696897A patent/IL126968A0/xx not_active IP Right Cessation
- 1997-05-02 AT AT03075959T patent/ATE350373T1/de not_active IP Right Cessation
- 1997-05-02 CN CN97194515A patent/CN1074766C/zh not_active Expired - Lifetime
- 1997-05-02 ES ES03075959T patent/ES2279923T3/es not_active Expired - Lifetime
- 1997-05-02 DE DE69737217T patent/DE69737217T2/de not_active Expired - Lifetime
- 1997-05-02 EE EE9800378A patent/EE03563B1/xx not_active IP Right Cessation
- 1997-05-02 BR BR9709065A patent/BR9709065A/pt not_active IP Right Cessation
- 1997-05-02 AU AU29560/97A patent/AU710175B2/en not_active Ceased
- 1997-05-02 CZ CZ19983553A patent/CZ295639B6/cs not_active IP Right Cessation
- 1997-05-02 EP EP03075959A patent/EP1325917B1/de not_active Expired - Lifetime
- 1997-05-02 NZ NZ332309A patent/NZ332309A/xx unknown
- 1997-05-02 CA CA002253453A patent/CA2253453C/en not_active Expired - Fee Related
- 1997-05-02 WO PCT/EP1997/002505 patent/WO1997043271A1/en not_active Ceased
- 1997-05-02 HU HU9902993A patent/HUP9902993A3/hu unknown
- 1997-05-02 EA EA199801000A patent/EA001360B1/ru not_active IP Right Cessation
- 1997-05-02 ES ES97923913T patent/ES2230605T3/es not_active Expired - Lifetime
- 1997-05-07 MY MYPI97002022A patent/MY117852A/en unknown
- 1997-05-09 AR ARP970101955A patent/AR007079A1/es active IP Right Grant
- 1997-05-09 ID IDP971546A patent/ID16889A/id unknown
- 1997-05-09 ZA ZA974053A patent/ZA974053B/xx unknown
1998
- 1998-10-07 BG BG102819A patent/BG64097B1/bg unknown
- 1998-11-09 NO NO19985227A patent/NO311027B1/no unknown
2000
- 2000-06-27 US US09/604,427 patent/US6224849B1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EE9800378A (et)	1999-04-15
HUP9902993A3 (en)	2002-01-28
AU710175B2 (en)	1999-09-16
DE69730962T2 (de)	2006-03-30
EP1325917B1 (de)	2007-01-03
MY117852A (en)	2004-08-30
KR100330699B1 (ko)	2002-08-27
US6103725A (en)	2000-08-15
KR20000005227A (ko)	2000-01-25
CN1218461A (zh)	1999-06-02
CA2253453C (en)	2007-01-16
SK282919B6 (sk)	2003-01-09
TR199802253T2 (xx)	1999-02-22
CZ295639B6 (cs)	2005-09-14
DE69730962D1 (de)	2004-11-04
NO311027B1 (no)	2001-10-01
CZ355398A3 (cs)	1999-02-17
IL126968A0 (en)	1999-09-22
ID16889A (id)	1997-11-20
NZ332309A (en)	1999-08-30
BG64097B1 (bg)	2003-12-31
HK1057044A1 (en)	2004-03-12
AR007079A1 (es)	1999-10-13
TW593290B (en)	2004-06-21
NO985227D0 (no)	1998-11-09
JP2000503667A (ja)	2000-03-28
HK1018457A1 (en)	1999-12-24
CA2253453A1 (en)	1997-11-20
ES2230605T3 (es)	2005-05-01
PL329849A1 (en)	1999-04-12
EP0912533B1 (de)	2004-09-29
BR9709065A (pt)	1999-08-03
JP3237759B2 (ja)	2001-12-10
WO1997043271A1 (en)	1997-11-20
BG102819A (en)	1999-08-31
ZA974053B (en)	1998-11-09
US6224849B1 (en)	2001-05-01
HUP9902993A2 (hu)	2000-05-28
CN1074766C (zh)	2001-11-14
EA199801000A1 (ru)	1999-04-29
DE69737217T2 (de)	2007-11-08
AU2956097A (en)	1997-12-05
PL190721B1 (pl)	2005-12-30
EE03563B1 (et)	2001-12-17
NO985227L (no)	1999-01-11
ES2279923T3 (es)	2007-09-01
SK153298A3 (en)	1999-03-12
DE69737217D1 (de)	2007-02-15
EA001360B1 (ru)	2001-02-26
ATE350373T1 (de)	2007-01-15
EP0912533A1 (de)	1999-05-06
EP1325917A1 (de)	2003-07-09

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DE69613368D1 (de)	2001-07-19	Chinazolin derivate
DE69613369D1 (de)	2001-07-19	Chinazolin derivate
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PT934320E (pt)	2003-07-31	Derivados de naftiridina
NO981946D0 (no)	1998-04-29	Imidazoquinazolin-derivater
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DE69809755D1 (de)	2003-01-09	Substituierte 1,2,3,4-tetrahydronaphthalin derivate
DE69730962D1 (de)	2004-11-04	Alkylaminobenzothiazole und -benzoxazole derivate
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ATE230405T1 (de)	2003-01-15	2-phenylpyran-4-one derivate
EE9900182A (et)	1999-12-15	2-metoksüfenüülpiperasiini derivaadid
ATE219051T1 (de)	2002-06-15	5-aroylnaphthalin derivate
PT906279E (pt)	2003-02-28	Derivados de pirrol
PT931087E (pt)	2002-09-30	Novos derivados de piranosido
ATE241599T1 (de)	2003-06-15	25-hydroxy-16-ene-26,27-bishome-cholecalcerifer l derivate
FI965181A7 (fi)	1998-06-21	Polyalkoholi-peptidijohdannaiset
BR9708310A (pt)	1999-08-03	Derivados de 2-tioxotetrahidropirimidin-4-ona

Legal Events

Date	Code	Title	Description
2005-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties