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AR064099A1 - Forma cristalina del hemihidrato de 1-(beta-d-glucopiranosil)-4-metil-3-[5-(4-fluorofenil)-2-tienilmetil]benceno - Google Patents

Forma cristalina del hemihidrato de 1-(beta-d-glucopiranosil)-4-metil-3-[5-(4-fluorofenil)-2-tienilmetil]benceno

Info

Publication number
AR064099A1
AR064099A1 ARP070105383A ARP070105383A AR064099A1 AR 064099 A1 AR064099 A1 AR 064099A1 AR P070105383 A ARP070105383 A AR P070105383A AR P070105383 A ARP070105383 A AR P070105383A AR 064099 A1 AR064099 A1 AR 064099A1
Authority
AR
Argentina
Prior art keywords
hemihydrate
fluorophenyl
beta
methyl
benzene
Prior art date
Application number
ARP070105383A
Other languages
English (en)
Inventor
Sumihiro Nomura
Eiji Kawanishi
Original Assignee
Mitsubishi Tanabe Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38973167&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR064099(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Mitsubishi Tanabe Pharma Corp filed Critical Mitsubishi Tanabe Pharma Corp
Publication of AR064099A1 publication Critical patent/AR064099A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/04—Carbocyclic radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Una forma cristalina del hemihidrato de 1-(beta-D-glucopiranosil)-4-metiI-3-[5-(4-fluorofenil)-2-tienilmetil] benceno, que tiene características favorables. Reivindicacion 2: Una forma cristalina del hemihidrato de la reivindicacion 1, caracterizado porque tiene un patron de difraccion de rayos X de polvo que comprende los siguientes valores 2theta medidos utilizando radiacion CuKalfa: 4,36 +- 0,2, 13,54 +- 0,2, 16,00 +- 0,2, 19,32 +- 0,2, y 20,80 +- 0,2.
ARP070105383A 2006-12-04 2007-12-03 Forma cristalina del hemihidrato de 1-(beta-d-glucopiranosil)-4-metil-3-[5-(4-fluorofenil)-2-tienilmetil]benceno AR064099A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86842606P 2006-12-04 2006-12-04
JP2006327019 2006-12-04

Publications (1)

Publication Number Publication Date
AR064099A1 true AR064099A1 (es) 2009-03-11

Family

ID=38973167

Family Applications (4)

Application Number Title Priority Date Filing Date
ARP070105383A AR064099A1 (es) 2006-12-04 2007-12-03 Forma cristalina del hemihidrato de 1-(beta-d-glucopiranosil)-4-metil-3-[5-(4-fluorofenil)-2-tienilmetil]benceno
ARP170100253A AR107510A2 (es) 2006-12-04 2017-02-01 FORMA CRISTALINA DEL HEMIHIDRATO DE 1-(b-D-GLUCOPIRANOSIL)-4-METIL-3-[5-(4-FLUOROFENIL)-2-TIENILMETIL]BENCENO Y PROCESO PARA LA PREPARACIÓN
ARP200100781A AR118450A2 (es) 2006-12-04 2020-03-19 FORMA CRISTALINA DEL HEMIHIDRATO DE 1-(b-D-GLUCOPIRANOSIL)-4-METIL-3-[5-(4-FLUOROFENIL)-2-TIENILMETIL]BENCENO
ARP230101829A AR129907A2 (es) 2006-12-04 2023-07-13 FORMA CRISTALINA DEL HEMIHIDRATO DE 1-(b-D-GLUCOPIRANOSIL)-4-METIL-3-[5-(4-FLUOROFENIL)-2-TIENILMETIL]BENCENO, COMPOSICIÓN FARMACÉUTICA, PROCESO PARA LA PREPARACIÓN Y USOS

Family Applications After (3)

Application Number Title Priority Date Filing Date
ARP170100253A AR107510A2 (es) 2006-12-04 2017-02-01 FORMA CRISTALINA DEL HEMIHIDRATO DE 1-(b-D-GLUCOPIRANOSIL)-4-METIL-3-[5-(4-FLUOROFENIL)-2-TIENILMETIL]BENCENO Y PROCESO PARA LA PREPARACIÓN
ARP200100781A AR118450A2 (es) 2006-12-04 2020-03-19 FORMA CRISTALINA DEL HEMIHIDRATO DE 1-(b-D-GLUCOPIRANOSIL)-4-METIL-3-[5-(4-FLUOROFENIL)-2-TIENILMETIL]BENCENO
ARP230101829A AR129907A2 (es) 2006-12-04 2023-07-13 FORMA CRISTALINA DEL HEMIHIDRATO DE 1-(b-D-GLUCOPIRANOSIL)-4-METIL-3-[5-(4-FLUOROFENIL)-2-TIENILMETIL]BENCENO, COMPOSICIÓN FARMACÉUTICA, PROCESO PARA LA PREPARACIÓN Y USOS

Country Status (34)

Country Link
US (2) US7943582B2 (es)
EP (1) EP2102224B2 (es)
JP (1) JP5159788B2 (es)
KR (1) KR101146095B1 (es)
CN (3) CN101573368B (es)
AR (4) AR064099A1 (es)
AU (1) AU2007329895C1 (es)
BR (1) BRPI0718882B8 (es)
CA (1) CA2671357C (es)
CL (1) CL2007003487A1 (es)
CO (1) CO6210719A2 (es)
CR (1) CR10861A (es)
DK (1) DK2102224T4 (es)
EA (1) EA017103B1 (es)
EC (1) ECSP099489A (es)
ES (1) ES2456640T5 (es)
GT (1) GT200900151A (es)
IL (1) IL199032A (es)
ME (1) ME01829B (es)
MX (1) MX2009005857A (es)
MY (1) MY153702A (es)
NO (1) NO344354B1 (es)
NZ (1) NZ577545A (es)
PA (1) PA8759401A1 (es)
PE (3) PE20081201A1 (es)
PL (1) PL2102224T5 (es)
PT (1) PT2102224E (es)
RS (1) RS53274B2 (es)
SI (1) SI2102224T2 (es)
SV (1) SV2009003285A (es)
TW (1) TWI403325B (es)
UY (1) UY30730A1 (es)
WO (1) WO2008069327A1 (es)
ZA (1) ZA200903941B (es)

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KR20140030231A (ko) 2011-06-03 2014-03-11 베링거 인겔하임 인터내셔날 게엠베하 신경이완제로 치료받는 환자에서 대사 장애를 치료하기 위한 ｓｇｌｔ－２ 억제제
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CN101573368A (zh) 2009-11-04
ZA200903941B (en) 2010-08-25
PL2102224T3 (pl) 2014-07-31
PE20110841A1 (es) 2011-11-24
KR101146095B1 (ko) 2012-05-16
TWI403325B (zh) 2013-08-01
NZ577545A (en) 2011-08-26
ME01829B (me) 2014-12-20
ECSP099489A (es) 2009-08-28
MX2009005857A (es) 2009-06-12
CA2671357A1 (en) 2008-06-12
SI2102224T2 (sl) 2021-11-30
AU2007329895C1 (en) 2014-03-13
EA200970540A1 (ru) 2009-10-30
US7943582B2 (en) 2011-05-17
AR118450A2 (es) 2021-10-06
GT200900151A (es) 2012-01-17
US8513202B2 (en) 2013-08-20
PA8759401A1 (es) 2009-04-23
CL2007003487A1 (es) 2008-03-14
US20080146515A1 (en) 2008-06-19
SI2102224T1 (sl) 2014-03-31
BRPI0718882A2 (pt) 2014-09-16

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