AR004503A1 - Uso de l-carnitina, l-carnitinas acilicas en las cuales el gruo acilo, lineal o ramificado, tiene entre 2 y 6 atomos de carbono y sus salesfarmaceuticamente aceptables, y composiciones farmaceuticas que comprenden tales compuestos - Google Patents
Uso de l-carnitina, l-carnitinas acilicas en las cuales el gruo acilo, lineal o ramificado, tiene entre 2 y 6 atomos de carbono y sus salesfarmaceuticamente aceptables, y composiciones farmaceuticas que comprenden tales compuestosInfo
- Publication number
- AR004503A1 AR004503A1 ARP960103844A AR10384496A AR004503A1 AR 004503 A1 AR004503 A1 AR 004503A1 AR P960103844 A ARP960103844 A AR P960103844A AR 10384496 A AR10384496 A AR 10384496A AR 004503 A1 AR004503 A1 AR 004503A1
- Authority
- AR
- Argentina
- Prior art keywords
- carnitine
- carnitines
- linear
- carbon atoms
- pharmaceutical compositions
- Prior art date
Links
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- 208000030507 AIDS Diseases 0.000 abstract 1
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- -1 acyl L-carnitines Chemical class 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 230000000798 anti-retroviral effect Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Emergency Medicine (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
La presente, proporciona un uso novedoso de L-carnitina, los derivados de la misma y sus sales farmacológicamente aceptables, en combinación con fármacosantirretrovirales anteriormente mencionados para el tratamiento terapéutico de infecciones por HIV y SIDA. Se describen además composiciones farmacéuticasque comprenden una cantidad de L-carnitina, L-carnitinas acílicas en las cuales el grupo acílico lineal o ramificado tiene entre 2 y 6 átomos de carbonoy las sales farmacéuticamenteaceptables de las mismas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT95RM000544A IT1277897B1 (it) | 1995-08-03 | 1995-08-03 | Uso della l-carnitina,di suoi derivati e di loro sali farmaceuticamen- te accettabili in combinazione con farmaci antiretrovirali per ridurre |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR004503A1 true AR004503A1 (es) | 1998-12-16 |
Family
ID=11403512
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP960103844A AR004503A1 (es) | 1995-08-03 | 1996-08-02 | Uso de l-carnitina, l-carnitinas acilicas en las cuales el gruo acilo, lineal o ramificado, tiene entre 2 y 6 atomos de carbono y sus salesfarmaceuticamente aceptables, y composiciones farmaceuticas que comprenden tales compuestos |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US6040346A (es) |
| EP (1) | EP0839033B1 (es) |
| JP (1) | JPH11510181A (es) |
| KR (1) | KR100412532B1 (es) |
| CN (1) | CN1161116C (es) |
| AR (1) | AR004503A1 (es) |
| AT (1) | ATE260654T1 (es) |
| AU (1) | AU719906B2 (es) |
| BR (1) | BR9609947A (es) |
| CA (1) | CA2228266C (es) |
| DE (1) | DE69631768T2 (es) |
| DK (1) | DK0839033T3 (es) |
| ES (1) | ES2216050T3 (es) |
| IT (1) | IT1277897B1 (es) |
| PT (1) | PT839033E (es) |
| RU (2) | RU2203047C2 (es) |
| TW (1) | TW464493B (es) |
| WO (1) | WO1997005864A2 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1277898B1 (it) | 1995-08-03 | 1997-11-12 | Mendes Srl | Uso di amminoacidi basici, di acil derivati di amminoacidi basici e di loro sali farmaceuticamente accettabili per la profilassi di malattie |
| IT1277897B1 (it) * | 1995-08-03 | 1997-11-12 | Mendes Srl | Uso della l-carnitina,di suoi derivati e di loro sali farmaceuticamen- te accettabili in combinazione con farmaci antiretrovirali per ridurre |
| US20010025027A1 (en) * | 2000-03-07 | 2001-09-27 | Sonis Stephen T. | Inhibition of ceramide for the prevention and treatment of oral mucositis induced by antineoplastic drugs or radiation |
| IT1317938B1 (it) * | 2000-11-17 | 2003-07-15 | Sigma Tau Healthscience Spa | Composizione per la prevenzione e/o il trattamento di alterazioni delmetabolismo lipidico, delle forme allergiche e per attivare le difese |
| EP2586438A1 (en) * | 2011-10-28 | 2013-05-01 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Compound useful for preventing cognitive deficit disorders in a new born from HIV-seropositive pregnant female who is in treatment with azidothymidine |
| RU2559179C1 (ru) * | 2014-03-24 | 2015-08-10 | Илья Александрович Марков | Фармацевтическая композиция для лечения тяжелых форм вирусных инфекций в виде таблеток |
| DE202017102551U1 (de) | 2017-04-28 | 2017-06-01 | E-Lead Electronic Co., Ltd. | Verstellbares Allzeit-Head-Up-Displaysystem |
| EP4125858A1 (en) * | 2020-04-28 | 2023-02-08 | Lonza Consumer Health Inc. | Nutritional composition comprising carnitine and method for treating or preventing an infection in a mammal |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5A (en) * | 1836-08-10 | Thomas Blanchard | Machine for mortising solid wooden shells of ships' tackle-blocks | |
| AU518617B2 (en) * | 1977-04-29 | 1981-10-08 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Therapeutic application of acetyl-d, 1-carnitine |
| IE903343A1 (en) * | 1989-09-18 | 1991-04-10 | Smithkline Beecham Corp | FORMULATION FOR SOLUBLE sT4 FOR TREATMENT OF HIV INFECTION |
| EP0507872B1 (en) * | 1989-12-29 | 2000-04-26 | B. Braun Medical Inc. | The use of arginine as an immunostimulator |
| IT1255039B (it) * | 1992-03-11 | 1995-10-13 | Sigma Tau Ind Farmaceuti | Impiego di l-carnitina nel trattamento di pazienti hiv-sieropositivi presentanti deficit di carnitina. |
| IT1277898B1 (it) * | 1995-08-03 | 1997-11-12 | Mendes Srl | Uso di amminoacidi basici, di acil derivati di amminoacidi basici e di loro sali farmaceuticamente accettabili per la profilassi di malattie |
| IT1277897B1 (it) * | 1995-08-03 | 1997-11-12 | Mendes Srl | Uso della l-carnitina,di suoi derivati e di loro sali farmaceuticamen- te accettabili in combinazione con farmaci antiretrovirali per ridurre |
| IT1283951B1 (it) * | 1996-03-15 | 1998-05-07 | Mendes Srl | Uso della acetil l-carnitina o dei suoi sali farmacologicamente accettabili per il trattamento terapeutico o la profilassi di |
-
1995
- 1995-08-03 IT IT95RM000544A patent/IT1277897B1/it active IP Right Grant
-
1996
- 1996-07-19 WO PCT/IT1996/000146 patent/WO1997005864A2/en not_active Ceased
- 1996-07-19 CN CNB961965290A patent/CN1161116C/zh not_active Expired - Fee Related
- 1996-07-19 EP EP96924124A patent/EP0839033B1/en not_active Expired - Lifetime
- 1996-07-19 JP JP9508282A patent/JPH11510181A/ja active Pending
- 1996-07-19 ES ES96924124T patent/ES2216050T3/es not_active Expired - Lifetime
- 1996-07-19 BR BR9609947A patent/BR9609947A/pt not_active Application Discontinuation
- 1996-07-19 RU RU98103506/14A patent/RU2203047C2/ru not_active IP Right Cessation
- 1996-07-19 DK DK96924124T patent/DK0839033T3/da active
- 1996-07-19 US US09/000,202 patent/US6040346A/en not_active Expired - Fee Related
- 1996-07-19 DE DE1996631768 patent/DE69631768T2/de not_active Expired - Lifetime
- 1996-07-19 PT PT96924124T patent/PT839033E/pt unknown
- 1996-07-19 CA CA002228266A patent/CA2228266C/en not_active Expired - Fee Related
- 1996-07-19 KR KR10-1998-0700817A patent/KR100412532B1/ko not_active Expired - Fee Related
- 1996-07-19 AT AT96924124T patent/ATE260654T1/de not_active IP Right Cessation
- 1996-07-19 AU AU64690/96A patent/AU719906B2/en not_active Ceased
- 1996-07-20 TW TW085108862A patent/TW464493B/zh not_active IP Right Cessation
- 1996-08-02 AR ARP960103844A patent/AR004503A1/es not_active Application Discontinuation
-
2001
- 2001-07-16 RU RU2001119623/14A patent/RU2269340C2/ru not_active IP Right Cessation
-
2003
- 2003-06-17 US US10/462,682 patent/US20040039054A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE69631768T2 (de) | 2005-01-13 |
| MX9800915A (es) | 1998-10-31 |
| DE69631768D1 (de) | 2004-04-08 |
| BR9609947A (pt) | 1999-02-02 |
| EP0839033B1 (en) | 2004-03-03 |
| CN1193912A (zh) | 1998-09-23 |
| WO1997005864A3 (en) | 1997-04-17 |
| CN1161116C (zh) | 2004-08-11 |
| HK1015273A1 (en) | 1999-10-15 |
| IT1277897B1 (it) | 1997-11-12 |
| ITRM950544A1 (it) | 1997-02-03 |
| AU719906B2 (en) | 2000-05-18 |
| WO1997005864A2 (en) | 1997-02-20 |
| ITRM950544A0 (it) | 1995-08-03 |
| RU2269340C2 (ru) | 2006-02-10 |
| TW464493B (en) | 2001-11-21 |
| DK0839033T3 (da) | 2004-06-21 |
| KR100412532B1 (ko) | 2004-06-10 |
| EP0839033A2 (en) | 1998-05-06 |
| AU6469096A (en) | 1997-03-05 |
| US6040346A (en) | 2000-03-21 |
| US20040039054A1 (en) | 2004-02-26 |
| RU2203047C2 (ru) | 2003-04-27 |
| CA2228266C (en) | 2009-05-12 |
| CA2228266A1 (en) | 1997-02-20 |
| ATE260654T1 (de) | 2004-03-15 |
| JPH11510181A (ja) | 1999-09-07 |
| KR19990036149A (ko) | 1999-05-25 |
| PT839033E (pt) | 2004-07-30 |
| ES2216050T3 (es) | 2004-10-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |