[go: up one dir, main page]

NO20060112L - Imidazolderivater III - Google Patents

Imidazolderivater III

Info

Publication number
NO20060112L
NO20060112L NO20060112A NO20060112A NO20060112L NO 20060112 L NO20060112 L NO 20060112L NO 20060112 A NO20060112 A NO 20060112A NO 20060112 A NO20060112 A NO 20060112A NO 20060112 L NO20060112 L NO 20060112L
Authority
NO
Norway
Prior art keywords
imidazole derivatives
derivatives iii
treatment
relates
chronic
Prior art date
Application number
NO20060112A
Other languages
English (en)
Inventor
Sabine Kolczewski
Bernd Buettelmann
Georg Jaeschke
Eric Vieira
Simona Maria Ceccarelli
Richard Hugh Phillip Porter
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20060112L publication Critical patent/NO20060112L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Foreliggende oppfinnelse angår imidazolderivater med den generelle formel hvor R^ R^, R^ og R'' er som definert i beskrivelsen så vel som farmasøytisk akseptable salter og prosesser for fremstillingen derav. Oppfinnelsen angår også medikamenter inneholdende nevnte imidazolderivater og til anvendelse av dem for fremstilling av medikamenter for behandling og forebygging av mGluR5 reseptor medierte lidelser så som akutt og/eller kronisk nevrologiske lidelser, spesielt angst eller for behandling av kronisk og akutt smerte.
NO20060112A 2003-07-03 2006-01-06 Imidazolderivater III NO20060112L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03014512 2003-07-03
PCT/EP2004/007177 WO2005003117A1 (en) 2003-07-03 2004-07-01 Imidazole derivatives iii

Publications (1)

Publication Number Publication Date
NO20060112L true NO20060112L (no) 2006-01-24

Family

ID=33560749

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20060112A NO20060112L (no) 2003-07-03 2006-01-06 Imidazolderivater III

Country Status (27)

Country Link
US (1) US7091222B2 (no)
EP (1) EP1644351B1 (no)
JP (1) JP4571631B2 (no)
KR (1) KR100719653B1 (no)
CN (1) CN100562520C (no)
AR (1) AR044973A1 (no)
AT (1) ATE388145T1 (no)
AU (1) AU2004253657B2 (no)
BR (1) BRPI0412158A (no)
CA (1) CA2531210C (no)
CO (1) CO5660258A2 (no)
DE (1) DE602004012268T2 (no)
DK (1) DK1644351T3 (no)
ES (1) ES2300789T3 (no)
HR (1) HRP20080173T3 (no)
IL (1) IL172821A (no)
MX (1) MXPA06000193A (no)
MY (1) MY142085A (no)
NO (1) NO20060112L (no)
NZ (1) NZ544454A (no)
PL (1) PL1644351T3 (no)
PT (1) PT1644351E (no)
RU (1) RU2360911C2 (no)
SI (1) SI1644351T1 (no)
TW (1) TWI252849B (no)
WO (1) WO2005003117A1 (no)
ZA (1) ZA200600026B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA80888C2 (en) * 2003-06-05 2007-11-12 Hoffmann La Roche Imidazole derivatives as glutmate receptor antagonists
US7452909B2 (en) * 2003-09-04 2008-11-18 Hoffman-La Roche Inc. Imidazole derivatives
NZ551253A (en) * 2004-06-01 2010-07-30 Hoffmann La Roche Pyridin-4-yl-ethynyl-imidazoles and pyrazoles as MGLU5 receptor antagonists
ATE397601T1 (de) * 2004-06-01 2008-06-15 Hoffmann La Roche Pyridin-4-yl-ethynylimidazole und -pyrazole als antagonisten des mglu5-rezeptors
US20060173048A1 (en) * 2005-02-03 2006-08-03 Mcarthur Silvia G Imidazole derivatives
DE102005062987A1 (de) * 2005-12-28 2007-07-05 Grünenthal GmbH Substituierte Propiolsäureamide und ihre Verwendung zur Herstellung von Arzneimitteln
PT2125779T (pt) 2006-12-21 2016-07-19 Hoffmann La Roche Polimorfos de um antagonista de um recetor de mglur5

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US304910A (en) * 1884-09-09 Robeet h
US4882343A (en) * 1987-08-28 1989-11-21 G. D. Searle & Co. Biarylalkylimidazole derivatives as anti-depressants
TW544448B (en) * 1997-07-11 2003-08-01 Novartis Ag Pyridine derivatives
US7531529B2 (en) * 2003-06-05 2009-05-12 Roche Palo Alto Llc Imidazole derivatives

Also Published As

Publication number Publication date
AU2004253657B2 (en) 2009-09-03
DE602004012268D1 (de) 2008-04-17
JP4571631B2 (ja) 2010-10-27
CA2531210C (en) 2012-05-29
NZ544454A (en) 2008-08-29
AU2004253657A1 (en) 2005-01-13
DK1644351T3 (da) 2008-06-23
SI1644351T1 (sl) 2008-06-30
HRP20080173T3 (hr) 2008-06-30
DE602004012268T2 (de) 2009-03-12
ATE388145T1 (de) 2008-03-15
PL1644351T3 (pl) 2008-08-29
KR100719653B1 (ko) 2007-05-18
US20050009878A1 (en) 2005-01-13
JP2009500291A (ja) 2009-01-08
CN100562520C (zh) 2009-11-25
BRPI0412158A (pt) 2006-08-22
ES2300789T3 (es) 2008-06-16
RU2006103009A (ru) 2006-08-27
CO5660258A2 (es) 2006-07-31
PT1644351E (pt) 2008-04-21
TWI252849B (en) 2006-04-11
IL172821A0 (en) 2006-06-11
WO2005003117A1 (en) 2005-01-13
EP1644351B1 (en) 2008-03-05
IL172821A (en) 2011-01-31
EP1644351A1 (en) 2006-04-12
KR20060029677A (ko) 2006-04-06
ZA200600026B (en) 2007-05-30
MXPA06000193A (es) 2006-04-11
US7091222B2 (en) 2006-08-15
RU2360911C2 (ru) 2009-07-10
MY142085A (en) 2010-08-30
AR044973A1 (es) 2005-10-12
CA2531210A1 (en) 2005-01-13
CN1823054A (zh) 2006-08-23
TW200514779A (en) 2005-05-01

Similar Documents

Publication Publication Date Title
GB0222495D0 (en) Compounds
PL367814A1 (en) 4,5-dihydro-1h-pyrazole derivatives having potent cb1-antagonistic activity
MXPA04002583A (es) Derivados de 4,5-dihidro-1h-pirazol novedosos que tienen actividad antagonistica del canabinoide (cb1).
MXPA05013075A (es) Inhibidores de p-38 basados en heterociclo de 5 miembros.
WO2005080343A3 (en) 3-substituted 1,5-diphenylpyrazole derivatives useful as cb1 modulators
UA92503C2 (ru) Соединения 5-(фенилизоксазолилэтокси)-триазол-3-ил-замещенного пиридина для лечения неврологических, психиатрических или болевых расстройств
TW200635903A (en) Therapeutic agents
WO2004074243A3 (en) Heterocyclyl-3-sulfonylindazoles as 5-hydroxytryptamine-6 ligands
MY147677A (en) Piperazinyl derivatives useful in the treatment of gpr38 receptor mediated diseases
TW200611695A (en) Pyrrolopyridine derivatives
NO20080563L (no) Pyrazol[3,4-d]azepinderivater som histamin H3 antagonister
MY141528A (en) Anilinopyrazole derivatives useful for the treatment of diabetes
NO20055465L (no) Imidazolderivater som glutamatreseptorantagonister
TW200633986A (en) Therapeutic agents
IL176546A0 (en) Imidazoline derivatives having cb1-antagonistic activity
TW200509933A (en) Therapeutic agents
EP1736470A3 (en) Pyrimidine derivatives as CB2 cannabinoid receptor modulators
NO20072060L (no) 2-acylaminotiazolderivater
TW200519101A (en) Benzimidazolone and quinazolinone derivatives as agonists on human ORL1 receptors
NO20060112L (no) Imidazolderivater III
NO20055758L (no) Heteroarylsubstituerte imidazolderivater som glutamatreseptorantagonister
MX2007006754A (es) Derivados de indenilo y uso de los mismos para el tratamiento de trastornos neurologicos.
TW200519102A (en) Hydronopol substituted benzimidazolone and quinazolinone derivatives as agonists on human ORL1 receptors
DK1373218T3 (da) Imidazolylderivater til anvendelse som histamin H3-receptorligander
JO2724B1 (en) 3-Alternative-5 -6-Amino Alkyl Indole-2-Carboxyl Acid Amide and Related Isotopes as Casein Kinase Inhibitors

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application