[go: up one dir, main page]

NO20072060L - 2-acylaminotiazolderivater - Google Patents

2-acylaminotiazolderivater

Info

Publication number
NO20072060L
NO20072060L NO20072060A NO20072060A NO20072060L NO 20072060 L NO20072060 L NO 20072060L NO 20072060 A NO20072060 A NO 20072060A NO 20072060 A NO20072060 A NO 20072060A NO 20072060 L NO20072060 L NO 20072060L
Authority
NO
Norway
Prior art keywords
acylaminotiazolderivater
compounds
receptor
implicated
neurological
Prior art date
Application number
NO20072060A
Other languages
English (en)
Inventor
Gitte Mikkelsen
Benny Bang-Andersen
Mogens Larsen
Anette Graven Sams
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of NO20072060L publication Critical patent/NO20072060L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Sammendrag Oppfinnelsen vedrører forbindelser med formel I, hvori variablene er som definert i kravene, for anvendelse som et medikament. Forbindelsene er A2A-reseptorligander og er nyttige i behandlingen av nevrologiske og psykiatriske lidelser hvor en A2A-reseptor er implisert. ?? ?? ?? ?? 1
NO20072060A 2004-09-22 2007-04-23 2-acylaminotiazolderivater NO20072060L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61223604P 2004-09-22 2004-09-22
DKPA200401441 2004-09-22
PCT/DK2005/000591 WO2006032273A1 (en) 2004-09-22 2005-09-20 2-acylaminothiazole derivatives

Publications (1)

Publication Number Publication Date
NO20072060L true NO20072060L (no) 2007-04-23

Family

ID=35169521

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20072060A NO20072060L (no) 2004-09-22 2007-04-23 2-acylaminotiazolderivater

Country Status (8)

Country Link
US (1) US7910613B2 (no)
EP (1) EP1794157B1 (no)
AU (1) AU2005287729A1 (no)
CA (1) CA2581105A1 (no)
EA (1) EA200700707A1 (no)
MX (1) MX2007003381A (no)
NO (1) NO20072060L (no)
WO (1) WO2006032273A1 (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3002283T1 (en) * 2003-12-26 2018-06-29 Kyowa Hakko Kirin Co., Ltd. Thiazole derivatives
US7674912B2 (en) 2005-04-25 2010-03-09 H. Lundbeck A/S Pro-drugs of N-thiazol-2-yl-benzamide derivatives
WO2006137527A1 (ja) * 2005-06-23 2006-12-28 Kyowa Hakko Kogyo Co., Ltd. チアゾール誘導体
HUE034666T2 (hu) 2005-08-02 2018-02-28 Kyowa Hakko Kirin Co Ltd Szer alvászavar kezelésére és/vagy megelõzésére
TWI473614B (zh) * 2008-05-29 2015-02-21 Kyowa Hakko Kirin Co Ltd Anti-analgesic inhibitors
NZ590793A (en) * 2008-07-23 2012-07-27 Kyowa Hakko Kirin Co Ltd Therapeutic agent for migraine
TWI548411B (zh) * 2009-04-28 2016-09-11 Kyowa Hakko Kirin Co Ltd Exercise disorder treatment
WO2018166855A1 (en) 2017-03-16 2018-09-20 Basf Se Heterobicyclic substituted dihydroisoxazoles

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE855120C (de) 1950-10-08 1953-01-05 Schering Ag Verfahren zur Herstellung von Aminosalicylsaeureamiden
CA2020437A1 (en) 1989-07-05 1991-01-06 Yoshihide Fuse Cinnamamide derivative
JP2903339B2 (ja) 1990-10-12 1999-06-07 大日精化工業株式会社 電子写真感光体
JP3181919B2 (ja) 1995-05-18 2001-07-03 ゼリア新薬工業株式会社 アミノチアゾール誘導体、それを含有する医薬及び該化合物の製造中間体
TW513418B (en) 1996-07-31 2002-12-11 Otsuka Pharma Co Ltd Thiazole derivatives, their production and use
US6121301A (en) 1996-10-24 2000-09-19 Zeria Pharmaceutical Co., Ltd. Substituted benzoylaminothiazole derivatives and drugs containing the same
AU4506399A (en) * 1998-06-05 1999-12-30 Novartis Ag Aryl pyridinyl thiazoles
GB9823871D0 (en) 1998-10-30 1998-12-23 Pharmacia & Upjohn Spa 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents
WO2000053573A1 (en) 1999-03-10 2000-09-14 Shionogi & Co., Ltd. Medicinal compositions with [2.2.1] and [3.1.1] bicycloskeleton antagonistic to both of pgd2/txa2 receptors
HUP0202708A3 (en) 1999-04-15 2004-12-28 Bristol Myers Squibb Co Cyclic protein tyrosine kinase inhibitors, pharmaceutical compositions containing them and their use
US7125875B2 (en) 1999-04-15 2006-10-24 Bristol-Myers Squibb Company Cyclic protein tyrosine kinase inhibitors
FR2796643B1 (fr) 1999-07-22 2005-04-29 Sod Conseils Rech Applic Derives de 2-arylimino-2, 3-dihydrothiazoles, leurs procedes de preparation et leur utilisation therapeutique
US7084136B2 (en) 2000-06-02 2006-08-01 Shionogi & Co., Ltd. Drug composition antagonistic to both PGD2/TXA2 receptors
GB0028383D0 (en) 2000-11-21 2001-01-03 Novartis Ag Organic compounds
GB0100624D0 (en) 2001-01-10 2001-02-21 Vernalis Res Ltd Chemical compounds VII
KR20040025891A (ko) 2001-01-26 2004-03-26 시오노기세이야쿠가부시키가이샤 트롬보포이에틴 수용체 효현작용을 갖는 할로겐 화합물
US7429593B2 (en) 2001-09-14 2008-09-30 Shionogi & Co., Ltd. Utilities of amide compounds
US6624163B2 (en) 2001-11-29 2003-09-23 Hoffman-La Roche Inc. Benzothiazole derivatives
US6713499B2 (en) 2001-12-12 2004-03-30 Hoffman-La Roche Inc. 7-Amino-benzothiazole derivatives
US20050043315A1 (en) 2002-01-02 2005-02-24 Hideo Tsutsumi Aminopyrimidine compounds, processes for their preparation and pharmaceutical compositions containing them
US20040209930A1 (en) 2002-10-02 2004-10-21 Carboni Joan M. Synergistic methods and compositions for treating cancer
DE60335294D1 (de) 2002-12-19 2011-01-20 Schering Corp Dlung des extrapyramidalen syndroms
DE10348022A1 (de) 2003-10-15 2005-05-25 Imtm Gmbh Neue Dipeptidylpeptidase IV-Inhibitoren zur funktionellen Beeinflussung unterschiedlicher Zellen und zur Behandlung immunologischer, entzündlicher, neuronaler und anderer Erkrankungen
TW200524887A (en) 2003-10-27 2005-08-01 Lundbeck & Co As H N-thiazol-2-yl-benzamide derivatives
SI3002283T1 (en) 2003-12-26 2018-06-29 Kyowa Hakko Kirin Co., Ltd. Thiazole derivatives
KR20130083488A (ko) 2004-09-02 2013-07-22 제넨테크, 인크. 헤지호그 신호전달에 대한 피리딜 억제제
EP1820504A1 (en) 2004-11-15 2007-08-22 Taisho Pharmaceutical Co., Ltd Imine compound
US7674912B2 (en) 2005-04-25 2010-03-09 H. Lundbeck A/S Pro-drugs of N-thiazol-2-yl-benzamide derivatives
HUE034666T2 (hu) 2005-08-02 2018-02-28 Kyowa Hakko Kirin Co Ltd Szer alvászavar kezelésére és/vagy megelõzésére
US20090005568A1 (en) 2005-08-18 2009-01-01 Pharmacopeia Drug Discovery, Inc. Substituted 2-aminothiazoles for treating neurodegenerative diseases

Also Published As

Publication number Publication date
EP1794157B1 (en) 2014-02-26
MX2007003381A (es) 2007-04-27
WO2006032273A1 (en) 2006-03-30
EA200700707A1 (ru) 2007-08-31
US7910613B2 (en) 2011-03-22
CA2581105A1 (en) 2006-03-30
EP1794157A1 (en) 2007-06-13
US20090137642A1 (en) 2009-05-28
AU2005287729A1 (en) 2006-03-30

Similar Documents

Publication Publication Date Title
NO20052796L (no) Indolylpyrazinonderivater anvendelige for behandling av hyper-proliferative forstyrrelser og sykdommer assosiert med angiogenese
MX2007000505A (es) Derivados de oxindol sustituidos y medicamentos que contienen los mismos.
NO20072060L (no) 2-acylaminotiazolderivater
CY1107956T1 (el) Χρηση υποκατεστημενων 2-αμινοτετραλινιων για την προληπτικη αντιμετωπιση της νοσου του παρκινσον
NO20060324L (no) [1,8]Naftyridin-2-oner og relaterte forbindelser for behandling av Schizofreni
NO20082136L (no) 1,5-substituerte indol-2-yl-amidderivater
NO20070606L (no) Inhibitorer av IAP
NO20071719L (no) Pyridylinhibitorer for "hedgehog"-signalisering
DE602004022668D1 (de) 5-gliedrige heterocyclische p-38 inhibitoren
MY135841A (en) Novel benzodioxoles
NO20032801L (no) Tiazolderivater for behandling av PPAR-relaterte forstyrrelser
EG26020A (en) Derivatives 3- (Hetero Aryl-AXY) -2- Alkyl -1- AZA Dicyclic Alkyl Carbides Alpha 7- NACHR for the treatment of diseases of the central nervous system
TW200531689A (en) Therapeutic agents
NO20082096L (no) Azaindol-2-karboksamidderivativer
NO20081434L (no) 5-(fenylisoksazolyletoksy)-triazol-3-yl substituert pyridinsammensetninger for behandling av neurologisk, psykiatrisk eller smerteforstyrrelser
DK2194053T3 (da) Methoxypiperidinderivater til brug i behandling af gastrointestinale forstyrrelser og forstyrrelser i centralnervesystemet.
TW200635903A (en) Therapeutic agents
TW200503710A (en) Novel compounds
NO20080394L (no) N-(arylalkyl)-1H-pyrrolopyridin-2-karboksamidderivater, fremstilling og anvendelse derav
NO20092035L (no) Tiazolylforbindelser anvendbare som kinaseinhibitorer
PL1620425T3 (pl) Podstawione 3-cyjanotiofenoacetamidy jako antagoniści receptora glukagonu
NO20071574L (no) Arylsulfonylstilbenderivater for behandling av insomni og beslektede tilstander.
IL183636A0 (en) Quinoline derivative, use and production thereof, and drug containing the same
NO20061137L (no) Cyklopropylderivater som NK3-reseptorantagonister
NO20062256L (no) Hydroksyalkylsubstituerte pyrido-7-pyrimidin-7-oner

Legal Events

Date Code Title Description
CREP Change of representative

Representative=s name: PLOUGMANN & VINGTOFT, POSTBOKS 1003 SENTRUM, 0104

FC2A Withdrawal, rejection or dismissal of laid open patent application