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NO20021251D0 - Tienoisoksazolyl- og tienylpyrrazolyl-fenoksysubstituerte propylderivater anvendelige som D4antagonister - Google Patents

Tienoisoksazolyl- og tienylpyrrazolyl-fenoksysubstituerte propylderivater anvendelige som D4antagonister

Info

Publication number
NO20021251D0
NO20021251D0 NO20021251A NO20021251A NO20021251D0 NO 20021251 D0 NO20021251 D0 NO 20021251D0 NO 20021251 A NO20021251 A NO 20021251A NO 20021251 A NO20021251 A NO 20021251A NO 20021251 D0 NO20021251 D0 NO 20021251D0
Authority
NO
Norway
Prior art keywords
tienoisoxazolyl
thienylpyrrazolyl
antagonists
phenoxy
derivatives useful
Prior art date
Application number
NO20021251A
Other languages
English (en)
Other versions
NO20021251L (no
Inventor
David M Fink
Brian Scott Freed
Nicholas Joseph Hrib
Jr Raymond Walter Kosley
George E Lee
Gregory Harold Merriman
Barbara Seavey Rauckman
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of NO20021251D0 publication Critical patent/NO20021251D0/no
Publication of NO20021251L publication Critical patent/NO20021251L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO20021251A 1999-09-14 2002-03-13 Tienoisoksazolyl- og tienylpyrrazolyl-fenoksysubstituerte propylderivater anvendbare som D4antagonister NO20021251L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39608199A 1999-09-14 1999-09-14
PCT/US2000/024962 WO2001019833A1 (en) 1999-09-14 2000-09-13 Thienoisoxazolyl- and thienylpyrrazolyl-phenoxy substituted propyl derivatives useful as d4 antagonists

Publications (2)

Publication Number Publication Date
NO20021251D0 true NO20021251D0 (no) 2002-03-13
NO20021251L NO20021251L (no) 2002-05-10

Family

ID=23565772

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20021251A NO20021251L (no) 1999-09-14 2002-03-13 Tienoisoksazolyl- og tienylpyrrazolyl-fenoksysubstituerte propylderivater anvendbare som D4antagonister

Country Status (26)

Country Link
EP (1) EP1216250B1 (no)
JP (1) JP4847662B2 (no)
KR (1) KR20020027647A (no)
AR (1) AR032134A1 (no)
AT (1) ATE254621T1 (no)
AU (1) AU7577400A (no)
BR (1) BR0014515A (no)
CA (1) CA2383340C (no)
CY (1) CY1101692T1 (no)
CZ (1) CZ2002897A3 (no)
DE (1) DE60006699T2 (no)
DK (1) DK1216250T3 (no)
EA (1) EA200200355A1 (no)
EE (1) EE200200135A (no)
ES (1) ES2209995T3 (no)
HR (1) HRP20020220A2 (no)
HU (1) HUP0203526A3 (no)
IL (1) IL148623A0 (no)
MX (1) MXPA02002695A (no)
NO (1) NO20021251L (no)
PL (1) PL354515A1 (no)
PT (1) PT1216250E (no)
SK (1) SK3512002A3 (no)
TW (1) TW530060B (no)
WO (1) WO2001019833A1 (no)
ZA (1) ZA200201762B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7125903B1 (en) 1999-09-14 2006-10-24 Aventis Pharmaceuticals Inc. Thienoisoxazolyl-and thienylpyrrazolyl-phenoxy substituted propyl derivatives useful as D4 antagonists
US7091199B1 (en) 1999-09-14 2006-08-15 Aventis Pharmaceuticals Inc. Thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives useful as d4 antagonists
US7253165B2 (en) 1999-09-14 2007-08-07 Aventis Pharmaceuticals Inc. Benzisoxazolyl-, pyridoisoxazolyl-and benzthienyl-phenoxy derivatives useful as D4 antagonists
WO2002066469A2 (en) * 2001-02-16 2002-08-29 Aventis Pharmaceuticals Inc. Novel heterocyclic amide derivatives and their use as dopamine d3 receptor ligands
CA2440842A1 (en) 2001-04-16 2002-10-24 Eisai Co., Ltd. Novel 1h-indazole compounds
KR20040020457A (ko) * 2002-08-30 2004-03-09 주식회사 대웅 3-｛2-[4-(6-플루오로벤조[ｄ]이속사졸-3-일)피페리디노]에틸｝-2-메틸-6,7,8,9-테트라하이드로-4Ｈ-피리도[1,2-ａ]피리미딘-4-온 또는 그 산부가염의 제조방법
KR20050092424A (ko) * 2003-01-17 2005-09-21 씨브이 쎄러퓨틱스, 인코포레이티드 심혈관 질환의 치료에 유용한 치환된 헤테로고리 화합물
JP2007297321A (ja) * 2006-04-28 2007-11-15 Daiso Co Ltd アリール２−メチルグリシジルエーテル類の製造法
JP2007297330A (ja) * 2006-04-28 2007-11-15 Daiso Co Ltd ２−メチルグリシジル誘導体の製造法
WO2014100716A1 (en) 2012-12-21 2014-06-26 Epizyme, Inc. Prmt5 inhibitors and uses thereof
JP2016505002A (ja) 2012-12-21 2016-02-18 エピザイム，インコーポレイティド ジヒドロイソキノリンまたはテトラヒドロイソキノリンを含有するｐｒｍｔ５阻害剤およびその使用
JP2016505597A (ja) 2012-12-21 2016-02-25 エピザイム，インコーポレイティド Ｐｒｍｔ５阻害剤およびその使用
US9604930B2 (en) 2012-12-21 2017-03-28 Epizyme, Inc. Tetrahydro- and dihydro-isoquinoline PRMT5 inhibitors and uses thereof
JP2016505000A (ja) * 2012-12-21 2016-02-18 エピザイム，インコーポレイティド Ｐｒｍｔ５阻害剤およびその使用
EP3160477A4 (en) * 2014-06-25 2018-07-04 Epizyme, Inc. Prmt5 inhibitors and uses thereof
WO2016022605A1 (en) 2014-08-04 2016-02-11 Epizyme, Inc. Prmt5 inhibitors and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4728651A (en) * 1985-10-24 1988-03-01 Hoechst-Roussel Pharmaceuticals Inc. Antihypertensive thieno-isoxazoles and -pyrazoles
US6187774B1 (en) * 1996-03-04 2001-02-13 Yoshitomi Pharmaceutical Industries, Ltd. Fused heterocyclic compounds and pharmaceutical applications thereof
HUP9603001A3 (en) * 1996-10-30 1999-07-28 Richter Gedeon Vegyeszet Heterocycle compounds comprising nitrogen, process for producing them and pharmaceutical compositions containing the same
WO1999040067A2 (en) * 1998-02-09 1999-08-12 Duphar International Research B.V. Benzisoxazole derivatives having d4-antagonistic activity

Also Published As

Publication number Publication date
HUP0203526A3 (en) 2004-12-28
HUP0203526A2 (hu) 2003-01-28
NO20021251L (no) 2002-05-10
EP1216250A1 (en) 2002-06-26
WO2001019833A1 (en) 2001-03-22
ATE254621T1 (de) 2003-12-15
BR0014515A (pt) 2002-06-25
HRP20020220A2 (en) 2004-02-29
MXPA02002695A (es) 2002-07-30
PT1216250E (pt) 2004-04-30
SK3512002A3 (en) 2003-03-04
CY1101692T1 (el) 2010-07-28
PL354515A1 (en) 2004-01-26
EP1216250B1 (en) 2003-11-19
AR032134A1 (es) 2003-10-29
KR20020027647A (ko) 2002-04-13
JP4847662B2 (ja) 2011-12-28
CA2383340C (en) 2010-06-15
CA2383340A1 (en) 2001-03-22
CZ2002897A3 (cs) 2002-07-17
IL148623A0 (en) 2002-09-12
JP2003509432A (ja) 2003-03-11
ZA200201762B (en) 2003-08-27
AU7577400A (en) 2001-04-17
EE200200135A (et) 2003-04-15
TW530060B (en) 2003-05-01
EA200200355A1 (ru) 2002-10-31
DE60006699T2 (de) 2004-09-30
DK1216250T3 (da) 2004-02-23
ES2209995T3 (es) 2004-07-01
DE60006699D1 (en) 2003-12-24

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