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MX2009006018A - Derivados de quinuclidinol como antagonistas de receptores muscarinicos. - Google Patents

Derivados de quinuclidinol como antagonistas de receptores muscarinicos.

Info

Publication number
MX2009006018A
MX2009006018A MX2009006018A MX2009006018A MX2009006018A MX 2009006018 A MX2009006018 A MX 2009006018A MX 2009006018 A MX2009006018 A MX 2009006018A MX 2009006018 A MX2009006018 A MX 2009006018A MX 2009006018 A MX2009006018 A MX 2009006018A
Authority
MX
Mexico
Prior art keywords
sup
receptor antagonists
muscarinic receptor
quinuclidinol derivatives
quinuclidinol
Prior art date
Application number
MX2009006018A
Other languages
English (en)
Inventor
Antonio Mete
Ian Millichip
Rhonan Ford
Barry Teobald
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39166793&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009006018(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of MX2009006018A publication Critical patent/MX2009006018A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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Abstract

La presente invención se refiere a compuestos de fórmula (I); en donde R5 es un grupo de fórmula (II) o (III) y R1, R2, R3, R4, R6, a, b, z, Y y X, son como se definen en la especificación, un proceso para su preparación, composiciones farmacéuticas que los contienen, un proceso para preparar composiciones farmacéuticas, su uso en terapia e intermediarios de uso en su preparación. (ver fórmulas (I, II y III)).
MX2009006018A 2006-12-19 2007-12-17 Derivados de quinuclidinol como antagonistas de receptores muscarinicos. MX2009006018A (es)

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BRPI0721039A2 (pt) 2014-07-29
AR064414A1 (es) 2009-04-01
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ATE555111T1 (de) 2012-05-15
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