ZA882416B - Natural pulmonary surfactant,method of preparation and pharmaceutical compositions - Google Patents
Natural pulmonary surfactant,method of preparation and pharmaceutical compositionsInfo
- Publication number
- ZA882416B ZA882416B ZA882416A ZA882416A ZA882416B ZA 882416 B ZA882416 B ZA 882416B ZA 882416 A ZA882416 A ZA 882416A ZA 882416 A ZA882416 A ZA 882416A ZA 882416 B ZA882416 B ZA 882416B
- Authority
- ZA
- South Africa
- Prior art keywords
- pulmonary surfactant
- preparation
- pharmaceutical compositions
- natural pulmonary
- surfactant
- Prior art date
Links
- 239000003580 lung surfactant Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 206010001052 Acute respiratory distress syndrome Diseases 0.000 abstract 1
- 208000013616 Respiratory Distress Syndrome Diseases 0.000 abstract 1
- 201000000028 adult respiratory distress syndrome Diseases 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 235000014633 carbohydrates Nutrition 0.000 abstract 1
- 238000005119 centrifugation Methods 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 150000003904 phospholipids Chemical class 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/42—Respiratory system, e.g. lungs, bronchi or lung cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0082—Lung surfactant, artificial mucus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Marine Sciences & Fisheries (AREA)
- Physiology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8720032A IT1203873B (it) | 1987-04-08 | 1987-04-08 | Composizioni farmaceutiche che lo surfattante polmonare naturale, contengono. metodo di preparazione e |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA882416B true ZA882416B (en) | 1988-09-28 |
Family
ID=11163272
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA882416A ZA882416B (en) | 1987-04-08 | 1988-04-07 | Natural pulmonary surfactant,method of preparation and pharmaceutical compositions |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5024995A (xx) |
| EP (1) | EP0286011B1 (xx) |
| JP (1) | JP2700323B2 (xx) |
| AT (1) | ATE99949T1 (xx) |
| AU (1) | AU619462B2 (xx) |
| CA (1) | CA1320440C (xx) |
| DE (2) | DE286011T1 (xx) |
| DK (1) | DK172921B1 (xx) |
| EG (1) | EG19626A (xx) |
| ES (1) | ES2004856T3 (xx) |
| FI (1) | FI92905C (xx) |
| GR (1) | GR890300026T1 (xx) |
| HK (1) | HK1007103A1 (xx) |
| HU (1) | HU211950A9 (xx) |
| IE (1) | IE61384B1 (xx) |
| IT (1) | IT1203873B (xx) |
| MY (1) | MY103260A (xx) |
| NO (1) | NO174733C (xx) |
| NZ (1) | NZ224146A (xx) |
| PH (1) | PH25300A (xx) |
| PT (1) | PT87188B (xx) |
| ZA (1) | ZA882416B (xx) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8803713D0 (sv) * | 1988-10-18 | 1988-10-18 | Kabigen Ab | Biologically active lipoprotein and its use |
| DE3921954A1 (de) * | 1989-07-04 | 1991-01-17 | Thomae Gmbh Dr K | Niedrig-viskose, hochkonzentrierte surfactant-suspension |
| CA2083171C (en) * | 1990-05-18 | 2002-09-10 | Kurashima Kazuyoshi | Antasthmatic |
| US5437272A (en) * | 1991-05-01 | 1995-08-01 | Alliance Pharmaceutical Corp. | Perfluorocarbon associated gas exchange |
| EP0583358B1 (en) * | 1991-05-03 | 1998-12-02 | Alliance Pharmaceutical Corporation | Partial liquid breathing of fluorocarbons |
| JPH07503629A (ja) * | 1991-11-14 | 1995-04-20 | アライアンス ファーマシューティカル コーポレイション | フルオロカーボンを用いた部分的液体呼吸法および装置 |
| IT1255967B (it) * | 1992-11-27 | 1995-11-17 | Chiesi Farma Spa | Procedimento per la purificazione di materiale surfattante polmonare naturale con l'impiego di fluidi supercritici |
| US5531219A (en) * | 1994-11-04 | 1996-07-02 | Alliance Pharmaceutical Corp. | Use of liquid fluorocarbons to facilitate pulmonary drug delivery |
| BR9506114A (pt) * | 1994-12-29 | 1997-12-23 | Ctro Nac Sanidad Agropecuaria | Tensoativo pulmonar de origem suína e processo para a sua obtenção |
| US6129934A (en) * | 1995-06-07 | 2000-10-10 | Ony, Inc. | Modification of animal lung surfactant for treating respiratory disease due to lung surfactant deficiency or dysfunction |
| US6172203B1 (en) * | 1996-02-07 | 2001-01-09 | Alfredo Adolfo Hager | Method for extracting and purifying pulmonary surfactant |
| WO1997029738A1 (en) * | 1996-02-16 | 1997-08-21 | The Administrators Of The Tulane Educational Fund | Methods and compositions for treating eustachian tube dysfunction by inhalation |
| AU6083899A (en) | 1999-09-16 | 2001-04-17 | Aventis Behring Gmbh | Combination of c1-inh and lung surfactant for the treatment of respiratory disorders |
| US6676930B2 (en) | 1999-11-28 | 2004-01-13 | Scientific Development And Research, Inc. | Composition and method for treatment of otitis media |
| US6156294A (en) | 1999-11-28 | 2000-12-05 | Scientific Development And Research, Inc. | Composition and method for treatment of otitis media |
| DE19957898A1 (de) * | 1999-12-01 | 2001-06-07 | Byk Gulden Lomberg Chem Fab | Neue Verwendung von Lungensurfactant |
| DE10018022A1 (de) * | 2000-04-12 | 2001-10-31 | Byk Gulden Lomberg Chem Fab | Neue Verwendung von Lungensurfactant zur Prophylaxe oder Frühbehandlung von akuten Lungenerkrankungen |
| EP1435994B1 (de) | 2001-10-11 | 2010-05-19 | Nycomed GmbH | Neue verwendung von lungensurfactant |
| RU2198670C1 (ru) * | 2002-02-19 | 2003-02-20 | ООО "Биосурф" | Способ получения сурфактанта из легких крупного рогатого скота |
| ATE457736T1 (de) | 2004-08-06 | 2010-03-15 | Nycomed Gmbh | Zusammensetzung aus einem pulmonalen surfactant und einem von tnf stammenden peptid |
| US7582312B2 (en) | 2004-11-15 | 2009-09-01 | Discovery Laboratories, Inc. | Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof |
| US8337815B2 (en) * | 2004-12-23 | 2012-12-25 | Discovery Laboratories, Inc. | Pulmonary surfactant formulations |
| SI1841458T1 (sl) | 2005-01-06 | 2012-04-30 | Discovery Lab Inc | Zdravljenje s predpisanim odmerjanjem surfaktanta za zdravljenje ali preprečevanje bronhopulmonalne displazije |
| GB2426703B (en) * | 2005-05-31 | 2007-09-19 | Malvern Cosmeceutics Ltd | Compositions |
| EP2063903A1 (en) * | 2006-09-19 | 2009-06-03 | Discovery Laboratories, Inc. | Pulmonary surfactant formulations and methods for promoting mucus clearance |
| US7951781B2 (en) | 2006-11-02 | 2011-05-31 | University Of Iowa Research Foundation | Methods and compositions related to PLUNC surfactant polypeptides |
| DE102007025898A1 (de) * | 2007-06-01 | 2008-12-04 | Matthias W. Dr. Amrein | Behandlung von Surfactanten |
| WO2010068754A2 (en) | 2008-12-10 | 2010-06-17 | Paka Pulmonary Pharmaceuticals, Inc. | Methods and compositions for delivery of medicaments to the lungs |
| JP2020526585A (ja) * | 2017-07-07 | 2020-08-31 | リポバイオメド コーポレイションＬｉｐｏｂｉｏｍｅｄ Ｃｏｒｐｏｒａｔｉｏｎ | 火傷及び褥瘡の緩和及び治療用組成物 |
| US11219843B2 (en) * | 2019-07-08 | 2022-01-11 | Nik Paya Karen Pharmed | Extraction of animal-derived pulmonary surfactants |
| WO2023280737A1 (en) | 2021-07-05 | 2023-01-12 | Chiesi Farmaceutici S.P.A. | Process for the preparation of a pulmonary surfactant |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55160721A (en) * | 1979-06-02 | 1980-12-13 | Tokyo Tanabe Co Ltd | Pulmonary surfactant ta-546, its preparation, and remedy for pulmonary hyaline membrane syndrome comprising it as active constituent |
| US4312860A (en) * | 1980-10-24 | 1982-01-26 | Regents Of The University Of California | Lung surfactant compositions |
| JPS5845299A (ja) * | 1981-09-10 | 1983-03-16 | 東京田辺製薬株式会社 | 新規な表面活性物質、その製造法及びそれを含有する呼吸窮迫疾候群治療剤 |
| JPS58222022A (ja) * | 1982-06-21 | 1983-12-23 | Teijin Ltd | 合成肺表面活性剤及びそれを有効成分とする呼吸窮迫症候群治療剤 |
| JPS59164724A (ja) * | 1983-03-10 | 1984-09-17 | Tokyo Tanabe Co Ltd | サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤 |
| BG49073A1 (en) * | 1983-12-08 | 1991-08-15 | Dresden Arzneimittel | Remedy for treatment of asthmatic syndrome caused by lack of surface- active substance and method for obtaining it |
| JPS6165821A (ja) * | 1984-09-07 | 1986-04-04 | Tokyo Tanabe Co Ltd | 合成サ−フアクタント及びそれを有効成分とする肺表面活性物質喪失性無気肺の治療剤 |
| FR2586587B1 (fr) * | 1985-08-30 | 1987-10-23 | Adir | Nouveaux surfactants artificiels, leur preparation et les compositions pharmaceutiques qui les contiennent. |
| JPS63503222A (ja) * | 1986-05-06 | 1988-11-24 | サイオス ノバ インコーポレイテッド | 肺の疎水性界面活性物質に結合した分子量６，０００ダルトンのタンパク質及びその多量体 |
-
1987
- 1987-04-08 IT IT8720032A patent/IT1203873B/it active
-
1988
- 1988-03-30 FI FI881508A patent/FI92905C/fi not_active IP Right Cessation
- 1988-03-31 EP EP88105232A patent/EP0286011B1/en not_active Expired - Lifetime
- 1988-03-31 ES ES88105232T patent/ES2004856T3/es not_active Expired - Lifetime
- 1988-03-31 DE DE198888105232T patent/DE286011T1/de active Pending
- 1988-03-31 DE DE3886970T patent/DE3886970T2/de not_active Expired - Lifetime
- 1988-03-31 AT AT88105232T patent/ATE99949T1/de not_active IP Right Cessation
- 1988-04-05 US US07/177,771 patent/US5024995A/en not_active Expired - Lifetime
- 1988-04-06 PH PH8836751A patent/PH25300A/en unknown
- 1988-04-06 IE IE100888A patent/IE61384B1/en not_active IP Right Cessation
- 1988-04-06 NZ NZ224146A patent/NZ224146A/en unknown
- 1988-04-07 NO NO881515A patent/NO174733C/no not_active IP Right Cessation
- 1988-04-07 ZA ZA882416A patent/ZA882416B/xx unknown
- 1988-04-07 AU AU14337/88A patent/AU619462B2/en not_active Expired
- 1988-04-07 JP JP63086214A patent/JP2700323B2/ja not_active Expired - Lifetime
- 1988-04-07 PT PT87188A patent/PT87188B/pt not_active IP Right Cessation
- 1988-04-07 CA CA000563558A patent/CA1320440C/en not_active Expired - Lifetime
- 1988-04-07 DK DK198801900A patent/DK172921B1/da not_active IP Right Cessation
- 1988-04-08 MY MYPI88000361A patent/MY103260A/en unknown
- 1988-04-10 EG EG20388A patent/EG19626A/xx active
-
1989
- 1989-04-12 GR GR89300026T patent/GR890300026T1/el unknown
-
1995
- 1995-06-30 HU HU95P/P00628P patent/HU211950A9/hu unknown
-
1998
- 1998-06-24 HK HK98106244A patent/HK1007103A1/en not_active IP Right Cessation
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