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PT87188A - A process for the preparation of a natural pulmonary surfactant and of pharmaceutical compositions containing - Google Patents

A process for the preparation of a natural pulmonary surfactant and of pharmaceutical compositions containing

Info

Publication number
PT87188A
PT87188A PT87188A PT8718888A PT87188A PT 87188 A PT87188 A PT 87188A PT 87188 A PT87188 A PT 87188A PT 8718888 A PT8718888 A PT 8718888A PT 87188 A PT87188 A PT 87188A
Authority
PT
Portugal
Prior art keywords
pulmonary surfactant
preparation
pharmaceutical compositions
compositions containing
natural pulmonary
Prior art date
Application number
PT87188A
Other languages
English (en)
Other versions
PT87188B (pt
Inventor
Bengt Robertson
Tore Curstedt
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of PT87188A publication Critical patent/PT87188A/pt
Publication of PT87188B publication Critical patent/PT87188B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/42—Respiratory system, e.g. lungs, bronchi or lung cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0082—Lung surfactant, artificial mucus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Physiology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
PT87188A 1987-04-08 1988-04-07 Processo para a preparacao de um tensioactivo pulmonar natural e de composicoes farmaceuticas que o contem PT87188B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8720032A IT1203873B (it) 1987-04-08 1987-04-08 Composizioni farmaceutiche che lo surfattante polmonare naturale, contengono. metodo di preparazione e

Publications (2)

Publication Number Publication Date
PT87188A true PT87188A (pt) 1988-05-01
PT87188B PT87188B (pt) 1992-07-31

Family

ID=11163272

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87188A PT87188B (pt) 1987-04-08 1988-04-07 Processo para a preparacao de um tensioactivo pulmonar natural e de composicoes farmaceuticas que o contem

Country Status (22)

Country Link
US (1) US5024995A (pt)
EP (1) EP0286011B1 (pt)
JP (1) JP2700323B2 (pt)
AT (1) ATE99949T1 (pt)
AU (1) AU619462B2 (pt)
CA (1) CA1320440C (pt)
DE (2) DE286011T1 (pt)
DK (1) DK172921B1 (pt)
EG (1) EG19626A (pt)
ES (1) ES2004856T3 (pt)
FI (1) FI92905C (pt)
GR (1) GR890300026T1 (pt)
HK (1) HK1007103A1 (pt)
HU (1) HU211950A9 (pt)
IE (1) IE61384B1 (pt)
IT (1) IT1203873B (pt)
MY (1) MY103260A (pt)
NO (1) NO174733C (pt)
NZ (1) NZ224146A (pt)
PH (1) PH25300A (pt)
PT (1) PT87188B (pt)
ZA (1) ZA882416B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8803713D0 (sv) * 1988-10-18 1988-10-18 Kabigen Ab Biologically active lipoprotein and its use
DE3921954A1 (de) * 1989-07-04 1991-01-17 Thomae Gmbh Dr K Niedrig-viskose, hochkonzentrierte surfactant-suspension
CA2083171C (en) * 1990-05-18 2002-09-10 Kurashima Kazuyoshi Antasthmatic
US5437272A (en) * 1991-05-01 1995-08-01 Alliance Pharmaceutical Corp. Perfluorocarbon associated gas exchange
JP2607021B2 (ja) 1991-05-03 1997-05-07 アライアンス ファーマシューティカル コーポレイション フルオロカーボンの部分液体呼吸
DE69226372T2 (de) * 1991-11-14 1999-04-01 Alliance Pharmaceutical Corp., San Diego, Calif. Vorrichtung zur teilweisen flüssigen beatmung mit fluorkohlenwasserstoffen
IT1255967B (it) * 1992-11-27 1995-11-17 Chiesi Farma Spa Procedimento per la purificazione di materiale surfattante polmonare naturale con l'impiego di fluidi supercritici
US5531219A (en) * 1994-11-04 1996-07-02 Alliance Pharmaceutical Corp. Use of liquid fluorocarbons to facilitate pulmonary drug delivery
CO5021218A1 (es) * 1994-12-29 2001-03-27 Ct Nac De Sanidad Agropecuaria Surfactante pulmonar natural porcino
US6129934A (en) * 1995-06-07 2000-10-10 Ony, Inc. Modification of animal lung surfactant for treating respiratory disease due to lung surfactant deficiency or dysfunction
US6172203B1 (en) * 1996-02-07 2001-01-09 Alfredo Adolfo Hager Method for extracting and purifying pulmonary surfactant
WO1997029738A1 (en) * 1996-02-16 1997-08-21 The Administrators Of The Tulane Educational Fund Methods and compositions for treating eustachian tube dysfunction by inhalation
EP1216052A1 (en) 1999-09-16 2002-06-26 Byk Gulden Lomberg Chemische Fabrik GmbH Combination of c1-inh and lung surfactant for the treatment of respiratory disorders
US6156294A (en) 1999-11-28 2000-12-05 Scientific Development And Research, Inc. Composition and method for treatment of otitis media
US6676930B2 (en) 1999-11-28 2004-01-13 Scientific Development And Research, Inc. Composition and method for treatment of otitis media
DE19957898A1 (de) * 1999-12-01 2001-06-07 Byk Gulden Lomberg Chem Fab Neue Verwendung von Lungensurfactant
DE10018022A1 (de) * 2000-04-12 2001-10-31 Byk Gulden Lomberg Chem Fab Neue Verwendung von Lungensurfactant zur Prophylaxe oder Frühbehandlung von akuten Lungenerkrankungen
JP4559731B2 (ja) 2001-10-11 2010-10-13 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 肺サーファクタントの新規使用
RU2198670C1 (ru) * 2002-02-19 2003-02-20 ООО "Биосурф" Способ получения сурфактанта из легких крупного рогатого скота
EP1781323B1 (en) 2004-08-06 2010-02-17 Nycomed GmbH Composition comprising a pulmonary surfactant and a tnf-derived peptide
US7582312B2 (en) * 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
US8337815B2 (en) * 2004-12-23 2012-12-25 Discovery Laboratories, Inc. Pulmonary surfactant formulations
ES2380046T3 (es) 2005-01-06 2012-05-08 Discovery Laboratories, Inc. Régimen para el tratamiento con tensioactivos para tratar o prevenir la displasia broncopulmonar
GB2426703B (en) * 2005-05-31 2007-09-19 Malvern Cosmeceutics Ltd Compositions
MX2009003002A (es) * 2006-09-19 2009-06-01 Discovery Lab Inc Formulaciones de tensioactivos pulmonares y metodos para promover la aclaracion del moco.
US7951781B2 (en) 2006-11-02 2011-05-31 University Of Iowa Research Foundation Methods and compositions related to PLUNC surfactant polypeptides
DE102007025898A1 (de) * 2007-06-01 2008-12-04 Matthias W. Dr. Amrein Behandlung von Surfactanten
EP2370068A4 (en) 2008-12-10 2015-09-23 Paka Pulmonary Pharmaceuticals Inc METHOD AND COMPOSITIONS FOR DELIVERING MEDICAMENTS TO THE LUNG
CN110996977A (zh) * 2017-07-07 2020-04-10 利珀生物实验室株式会社 用于缓解或治疗灼伤及褥疮的组合物
US11219843B2 (en) * 2019-07-08 2022-01-11 Nik Paya Karen Pharmed Extraction of animal-derived pulmonary surfactants
TW202317609A (zh) 2021-07-05 2023-05-01 義大利商吉斯藥品公司 肺部表面張力素之製備方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55160721A (en) * 1979-06-02 1980-12-13 Tokyo Tanabe Co Ltd Pulmonary surfactant ta-546, its preparation, and remedy for pulmonary hyaline membrane syndrome comprising it as active constituent
US4312860A (en) * 1980-10-24 1982-01-26 Regents Of The University Of California Lung surfactant compositions
JPS5845299A (ja) * 1981-09-10 1983-03-16 東京田辺製薬株式会社 新規な表面活性物質、その製造法及びそれを含有する呼吸窮迫疾候群治療剤
JPS58222022A (ja) * 1982-06-21 1983-12-23 Teijin Ltd 合成肺表面活性剤及びそれを有効成分とする呼吸窮迫症候群治療剤
JPS59164724A (ja) * 1983-03-10 1984-09-17 Tokyo Tanabe Co Ltd サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤
BG49073A1 (en) * 1983-12-08 1991-08-15 Dresden Arzneimittel Remedy for treatment of asthmatic syndrome caused by lack of surface- active substance and method for obtaining it
JPS6165821A (ja) * 1984-09-07 1986-04-04 Tokyo Tanabe Co Ltd 合成サ−フアクタント及びそれを有効成分とする肺表面活性物質喪失性無気肺の治療剤
FR2586587B1 (fr) * 1985-08-30 1987-10-23 Adir Nouveaux surfactants artificiels, leur preparation et les compositions pharmaceutiques qui les contiennent.
JPS63503222A (ja) * 1986-05-06 1988-11-24 サイオス　ノバ　インコーポレイテッド 肺の疎水性界面活性物質に結合した分子量６，０００ダルトンのタンパク質及びその多量体

Also Published As

Publication number Publication date
DE3886970T2 (de) 1994-05-26
ES2004856T3 (es) 1994-12-16
DE3886970D1 (de) 1994-02-24
NO881515D0 (no) 1988-04-07
PH25300A (en) 1991-04-30
IE881008L (en) 1988-10-08
EP0286011A3 (en) 1990-02-07
AU619462B2 (en) 1992-01-30
ES2004856A4 (es) 1989-02-16
MY103260A (en) 1993-05-29
EG19626A (en) 1995-09-30
DE286011T1 (de) 1989-03-09
US5024995A (en) 1991-06-18
NO174733C (no) 1994-06-29
FI92905B (fi) 1994-10-14
IT1203873B (it) 1989-02-23
PT87188B (pt) 1992-07-31
EP0286011A2 (en) 1988-10-12
HK1007103A1 (en) 1999-04-01
HU211950A9 (en) 1996-01-29
NZ224146A (en) 1991-06-25
AU1433788A (en) 1988-10-13
IE61384B1 (en) 1994-11-02
DK190088D0 (da) 1988-04-07
ZA882416B (en) 1988-09-28
CA1320440C (en) 1993-07-20
EP0286011B1 (en) 1994-01-12
DK172921B1 (da) 1999-10-04
GR890300026T1 (en) 1989-04-12
JPS6463526A (en) 1989-03-09
FI92905C (fi) 1995-01-25
DK190088A (da) 1988-10-09
IT8720032A0 (it) 1987-04-08
JP2700323B2 (ja) 1998-01-21
NO174733B (no) 1994-03-21
FI881508A0 (fi) 1988-03-30
NO881515L (no) 1988-10-10
FI881508L (fi) 1988-10-09
ATE99949T1 (de) 1994-01-15

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920127

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20080407