[go: up one dir, main page]

ZA200701199B - ( 1S,5S)-3-(5,6-dichloropyridin-3-yl)-3,6-diazabicyclo [3.2.0]heptane benzenesulfonate - Google Patents

( 1S,5S)-3-(5,6-dichloropyridin-3-yl)-3,6-diazabicyclo [3.2.0]heptane benzenesulfonate

Info

Publication number
ZA200701199B
ZA200701199B ZA200701199A ZA200701199A ZA200701199B ZA 200701199 B ZA200701199 B ZA 200701199B ZA 200701199 A ZA200701199 A ZA 200701199A ZA 200701199 A ZA200701199 A ZA 200701199A ZA 200701199 B ZA200701199 B ZA 200701199B
Authority
ZA
South Africa
Prior art keywords
dichloropyridin
diazabicyclo
heptane benzenesulfonate
benzenesulfonate
heptane
Prior art date
Application number
ZA200701199A
Other languages
English (en)
Inventor
Greg S Wayne
Geoff G Zhang
Jeffrey M Breting
Sean M Mellican
David R Willcox
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of ZA200701199B publication Critical patent/ZA200701199B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
ZA200701199A 2004-07-23 2007-02-09 ( 1S,5S)-3-(5,6-dichloropyridin-3-yl)-3,6-diazabicyclo [3.2.0]heptane benzenesulfonate ZA200701199B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59067704P 2004-07-23 2004-07-23

Publications (1)

Publication Number Publication Date
ZA200701199B true ZA200701199B (en) 2009-09-30

Family

ID=35774195

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA200701199A ZA200701199B (en) 2004-07-23 2007-02-09 ( 1S,5S)-3-(5,6-dichloropyridin-3-yl)-3,6-diazabicyclo [3.2.0]heptane benzenesulfonate
ZA200903093A ZA200903093B (en) 2004-07-23 2009-05-05 (1S,5S)-3-(5,6-dichloropyridin-3-yl)-3,6-diazabicyclo[3.2.0] heptane benzenesulfonate

Family Applications After (1)

Application Number Title Priority Date Filing Date
ZA200903093A ZA200903093B (en) 2004-07-23 2009-05-05 (1S,5S)-3-(5,6-dichloropyridin-3-yl)-3,6-diazabicyclo[3.2.0] heptane benzenesulfonate

Country Status (22)

Country Link
US (3) US7351833B2 (fr)
EP (1) EP1771451B1 (fr)
JP (1) JP4806408B2 (fr)
KR (1) KR20070039603A (fr)
CN (2) CN102772408A (fr)
AT (1) ATE480541T1 (fr)
AU (2) AU2005275299B2 (fr)
BR (1) BRPI0513727A (fr)
CA (1) CA2574896C (fr)
CY (1) CY1110934T1 (fr)
DE (1) DE602005023467D1 (fr)
DK (1) DK1771451T3 (fr)
ES (1) ES2350239T3 (fr)
IL (1) IL180882A (fr)
MX (1) MX2007000889A (fr)
NZ (1) NZ552803A (fr)
PL (1) PL1771451T3 (fr)
PT (1) PT1771451E (fr)
SI (1) SI1771451T1 (fr)
TW (1) TWI356825B (fr)
WO (1) WO2006019668A2 (fr)
ZA (2) ZA200701199B (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007536210A (ja) * 2003-11-17 2007-12-13 メルック・エプロバ・アクチエンゲゼルシヤフト （６ｒ）−ｌ−エリスロ−テトラヒドロビオプテリンジヒドロクロライドの結晶形
ATE518865T1 (de) * 2004-06-02 2011-08-15 Sandoz Ag Meropenem-zwischenprodukt in kristalliner form
EP1910393A2 (fr) * 2005-07-05 2008-04-16 Hetero Drugs Limited Nouveau procede de preparation de didanosine au moyen de nouveaux produits intermediaires
CN101287706A (zh) * 2005-09-21 2008-10-15 尼科梅德有限责任公司 作为组蛋白脱乙酰基酶抑制剂的磺酰基吡咯盐酸盐
JP2009513702A (ja) * 2005-10-31 2009-04-02 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ピペラジニルおよびジアザパニルベンズアミド誘導体の新規な製造方法
HRP20110412T1 (hr) * 2006-06-16 2011-06-30 H. Lundbeck A/S Kristalni oblici 4-[2-4-(4-metilfenilsulfanil)fenil]piperidina sa kombiniranom inhibicijom reapsorpcije serotonina i norepinefrina za liječenje neuropatskih bolova
WO2008028903A2 (fr) 2006-09-04 2008-03-13 Neurosearch A/S Compositions pharmaceutiques
KR20090084891A (ko) * 2006-10-27 2009-08-05 시그날 파마소티칼 엘엘씨 4-[9-(테트라하이드로-퓨란-3-일)-8-(2,4,6-트리플루오로-페닐아미노)-9ｈ-퓨린-2-일아미노]-사이클로헥산-1-올을 포함하는 고체 형태들, 이들의 조성물들 및 이들의 용도
EP2085397A1 (fr) * 2008-01-21 2009-08-05 Esteve Quimica, S.A. Forme cristalline d'abacavir
US7935817B2 (en) * 2008-03-31 2011-05-03 Apotex Pharmachem Inc. Salt form and cocrystals of adefovir dipivoxil and processes for preparation thereof
AR071318A1 (es) * 2008-04-15 2010-06-09 Basilea Pharmaceutica Ag Benzhidril ester del acido (6r,7r)-7-{2-(5-amino-[1,2,4]tiadiazol-3-il)-2-[(z)-tritiloxiimino]-acetilamino}-3-[(r)-1'-terc-butoxicarbonil-2-oxo-[1,3']bipirrolidinil-(3e)-ilidenometil]-8-oxo-5-tia-1-aza-biciclo[4.2.0]oct-2-eno-2-carboxilico cristalino; su elaboracion y uso
US8278311B2 (en) * 2008-04-28 2012-10-02 Abbott Laboratories Substituted pyrimidine derivatives
US8222278B2 (en) 2008-06-03 2012-07-17 Abbott Laboratories Treatment of attention-deficit/hyperactivity disorder
US8097719B2 (en) * 2008-07-15 2012-01-17 Genesen Labs Meropenem intermediate in novel crystalline form and a method of manufacture of meropenem
KR101713453B1 (ko) 2010-03-12 2017-03-07 오메로스 코포레이션 Pde10 억제제 및 관련 조성물 및 방법
EP2611433A2 (fr) * 2010-09-01 2013-07-10 Arena Pharmaceuticals, Inc. Sels non hygroscopiques d'agonistes de 5-ht2c
US9005737B2 (en) 2011-03-21 2015-04-14 Apogee Enterprises, Inc. Coated articles and methods of making same
US9174973B2 (en) * 2011-09-30 2015-11-03 Sunshine Lake Pharma Co., Ltd. Crystalline forms of azilsartan and preparation and uses thereof
NZ630810A (en) 2014-04-28 2016-03-31 Omeros Corp Processes and intermediates for the preparation of a pde10 inhibitor
NZ716462A (en) * 2014-04-28 2017-11-24 Omeros Corp Optically active pde10 inhibitor
CA2980801A1 (fr) 2015-04-24 2016-10-27 Omeros Corporation Inhibiteurs de pde10 ainsi que compositions et procedes associes
CA3003611C (fr) 2015-11-04 2022-11-01 Omeros Corporation Formes solides d'un inhibiteur de pde10
US10669236B2 (en) * 2017-09-07 2020-06-02 Athenex HK Innovative Limited Solid forms of 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide
US20210393621A1 (en) 2018-10-26 2021-12-23 The Research Foundation For The State University Of New York Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia
CN111303230B (zh) * 2020-03-09 2021-07-13 中国食品药品检定研究院 一种黄体酮共晶物及其制备方法和用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY137020A (en) * 2000-04-27 2008-12-31 Abbott Lab Diazabicyclic central nervous system active agents
US20040242644A1 (en) * 2003-05-27 2004-12-02 Buckley Michael J. (IS-5S)-3-(5,6-dichloro-3-pyridinyl-)-3,6-diazabicyclo[3.2.0]heptane is an effective analgesic agent
US7354937B2 (en) * 2004-05-21 2008-04-08 Abbott Laboratories (1S,5S)-3-(5,6-dichloro-3-pyridinyl)-3,6-diazabicyclo[3.2.0]heptane
US20040242641A1 (en) 2003-05-27 2004-12-02 Buckley Michael J. (1S,5S)-3-(5,6-dichloro-3-pyridinyl)-3,6-diazabicyclo[3.2.0]heptane is an effective analgesic agent
US20050261348A1 (en) * 2004-05-21 2005-11-24 Buckley Michael J (1S,5S)-3-(5,6-dichloro-3-pyridinyl)-3,6-diazabicyclo[3.2.0]heptane is an effective analgesic agent

Also Published As

Publication number Publication date
CN101035790A (zh) 2007-09-12
AU2005275299A1 (en) 2006-02-23
CA2574896A1 (fr) 2006-02-23
CN102772408A (zh) 2012-11-14
PL1771451T3 (pl) 2011-03-31
AU2005275299B2 (en) 2011-09-22
DK1771451T3 (da) 2010-12-06
TW200617012A (en) 2006-06-01
CY1110934T1 (el) 2015-06-10
CN101035790B (zh) 2012-09-26
US20090198067A1 (en) 2009-08-06
AU2009202832A1 (en) 2009-08-06
ATE480541T1 (de) 2010-09-15
TWI356825B (en) 2012-01-21
HK1101690A1 (en) 2007-10-26
SI1771451T1 (sl) 2010-11-30
BRPI0513727A (pt) 2008-05-13
US7351833B2 (en) 2008-04-01
ES2350239T3 (es) 2011-01-20
IL180882A0 (en) 2007-07-04
US7902371B2 (en) 2011-03-08
WO2006019668A2 (fr) 2006-02-23
DE602005023467D1 (de) 2010-10-21
CA2574896C (fr) 2012-01-03
AU2009202832B2 (en) 2011-11-10
NZ552803A (en) 2011-02-25
US20060035937A1 (en) 2006-02-16
ZA200903093B (en) 2010-01-27
JP2008507517A (ja) 2008-03-13
US20080004448A1 (en) 2008-01-03
MX2007000889A (es) 2007-04-18
PT1771451E (pt) 2010-11-10
US7498444B2 (en) 2009-03-03
EP1771451B1 (fr) 2010-09-08
IL180882A (en) 2011-02-28
WO2006019668A3 (fr) 2006-04-20
KR20070039603A (ko) 2007-04-12
JP4806408B2 (ja) 2011-11-02
EP1771451A2 (fr) 2007-04-11

Similar Documents

Publication Publication Date Title
IL180882A0 (en) (1s,5s)-3-(5,6-dichloropyridin-3-yl)-3-6-diazabicyclo[3.2.0]heptane benzenesulfonate
CL2013002895A1 (es) Compuestos derivados de 7,8-dihidro-5h-pteridin-6-ona, utiles como intermediarios en la sintesis de compuestos derivados de pteridinona (divisional de la solicitud 3123-2005).
MXPA05013752A (es) Procedimiento e intermediarios para la preparacion de (1r,2s,5s)-6,6-dimetil-3-azabiciclo[3,1,0]exan-2-carboxilatos o sales de los mismos.
TW200637853A (en) Fungicides
WO2004108139A8 (fr) Utilisation de composes heterocycliques en tant qu'inhibiteurs de scce
WO2005030751A3 (fr) Inhibiteurs de dipeptidyle peptidase
GEP20094785B (en) Pyrrolopyrazoles, potent kinase inhibitors
TW200626559A (en) Anilino-pyrimidine analogs
MX2007006397A (es) Derivados de tetrahidropirano.
WO2006015159A3 (fr) Inhibiteurs de canal a potassium
WO2005030130A3 (fr) Inhibiteurs des canaux potassiques a l'isoquinoleine
WO2005021544A3 (fr) Inhibiteurs d'un ensemble d'imidazopyridine c n3 substitue
TW200637837A (en) Fungicides
MXPA05013751A (es) Procedimiento e intermediarios para la preparacion de 3-(amino)-3-ciclobutilmetil-2-hidroxi-propionamida o sus sales.
TW200619206A (en) Chemokine-binding heterocyclic compound salts, and methods of use thereof
WO2004099388A3 (fr) Complexes de polypeptides cbl-b et methodes associees
ATE549024T1 (de) Chinazolin-kaliumkanalhemmer
WO2005030792A3 (fr) Inhibiteurs du canal potassique de quinoline
DE602004029671D1 (de) (1s,5s)-3-(5,6-dichloro-3-pyridinyl)-3,6-diazabicycloä3.2.0üheptan mit analgetischer wirksamkeit
WO2003076426A3 (fr) Composes therapeutiques
ITMI20030778A1 (it) Procedimento per la preparazione enzimatica dell'aroma di vaniglia.
EP1615897A4 (fr) Composes pyrimidinone en tant que calcilytiques
WO2004089302A3 (fr) Polypeptides posh, complexes et procedes correspondants
TW200616631A (en) (1s,5s)-3-(5,6-dichloro-3-pyridinyl)-3,6-diazabicyclo[3.2.0]heptane
AU2003289871A1 (en) 2-mercapto-substituted triazolopyrimidines, methods for the production thereof, the use of the same for controlling pathogenic fungi, and agents containing said compounds