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CL2013002895A1 - Compuestos derivados de 7,8-dihidro-5h-pteridin-6-ona, utiles como intermediarios en la sintesis de compuestos derivados de pteridinona (divisional de la solicitud 3123-2005). - Google Patents

Compuestos derivados de 7,8-dihidro-5h-pteridin-6-ona, utiles como intermediarios en la sintesis de compuestos derivados de pteridinona (divisional de la solicitud 3123-2005).

Info

Publication number
CL2013002895A1
CL2013002895A1 CL2013002895A CL2013002895A CL2013002895A1 CL 2013002895 A1 CL2013002895 A1 CL 2013002895A1 CL 2013002895 A CL2013002895 A CL 2013002895A CL 2013002895 A CL2013002895 A CL 2013002895A CL 2013002895 A1 CL2013002895 A1 CL 2013002895A1
Authority
CL
Chile
Prior art keywords
compounds derived
pteridinone
pteridin
divisional
dihydro
Prior art date
Application number
CL2013002895A
Other languages
English (en)
Inventor
Guenter Linz
Adil Duran
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35923724&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2013002895(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of CL2013002895A1 publication Critical patent/CL2013002895A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D475/00Heterocyclic compounds containing pteridine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/26Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28Oxygen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CL2013002895A 2004-12-02 2013-10-09 Compuestos derivados de 7,8-dihidro-5h-pteridin-6-ona, utiles como intermediarios en la sintesis de compuestos derivados de pteridinona (divisional de la solicitud 3123-2005). CL2013002895A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004058337A DE102004058337A1 (de) 2004-12-02 2004-12-02 Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten

Publications (1)

Publication Number Publication Date
CL2013002895A1 true CL2013002895A1 (es) 2014-03-14

Family

ID=35923724

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2013002895A CL2013002895A1 (es) 2004-12-02 2013-10-09 Compuestos derivados de 7,8-dihidro-5h-pteridin-6-ona, utiles como intermediarios en la sintesis de compuestos derivados de pteridinona (divisional de la solicitud 3123-2005).

Country Status (34)

Country Link
US (9) US7238807B2 (es)
EP (2) EP2436685B1 (es)
JP (1) JP5164574B2 (es)
KR (2) KR101362131B1 (es)
CN (3) CN101065381B (es)
AR (1) AR053100A1 (es)
AU (1) AU2005311308B2 (es)
BR (1) BRPI0518601A2 (es)
CA (1) CA2588857C (es)
CL (1) CL2013002895A1 (es)
CY (1) CY1113625T1 (es)
DE (1) DE102004058337A1 (es)
DK (2) DK1819706T3 (es)
EA (1) EA012624B1 (es)
ES (2) ES2548680T3 (es)
HR (1) HRP20120980T1 (es)
HU (1) HUE027689T2 (es)
IL (1) IL183568A (es)
ME (1) ME01470B (es)
MX (1) MX2007006549A (es)
MY (1) MY147459A (es)
NO (1) NO20072283L (es)
NZ (1) NZ556182A (es)
PE (2) PE20090488A1 (es)
PL (2) PL1819706T3 (es)
PT (1) PT1819706E (es)
RS (1) RS52533B (es)
SG (2) SG141461A1 (es)
SI (1) SI1819706T1 (es)
TW (1) TWI362391B (es)
UA (1) UA89390C2 (es)
UY (1) UY29233A1 (es)
WO (1) WO2006058876A1 (es)
ZA (1) ZA200703368B (es)

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EP1630163A1 (de) * 2004-08-25 2006-03-01 Boehringer Ingelheim Pharma GmbH & Co.KG Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
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DE102004058337A1 (de) * 2004-12-02 2006-06-14 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten
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CN103492391A (zh) 2009-09-25 2014-01-01 沃泰克斯药物股份有限公司 用于制备用作蛋白激酶抑制剂的嘧啶衍生物的方法
MX2012003484A (es) 2009-09-25 2012-04-20 Vertex Pharma Metodos para preparar derivados de pirimidina utiles como inhibidores de proteina cinasa.
US8546566B2 (en) 2010-10-12 2013-10-01 Boehringer Ingelheim International Gmbh Process for manufacturing dihydropteridinones and intermediates thereof
US9358233B2 (en) 2010-11-29 2016-06-07 Boehringer Ingelheim International Gmbh Method for treating acute myeloid leukemia
AR085406A1 (es) 2011-02-25 2013-09-25 Takeda Pharmaceutical Oxazinopteridinas y oxazinopteridinonas n-sustituidas
US9370535B2 (en) 2011-05-17 2016-06-21 Boehringer Ingelheim International Gmbh Method for treatment of advanced solid tumors
TW201414734A (zh) 2012-07-10 2014-04-16 Takeda Pharmaceutical 氮雜吲哚衍生物
JP2016525532A (ja) 2013-07-26 2016-08-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 骨髄異形成症候群の処置
TW201620904A (zh) 2014-01-09 2016-06-16 武田藥品工業有限公司 氮雜吲哚衍生物
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DE102004033670A1 (de) * 2004-07-09 2006-02-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Pyridodihydropyrazinone, Verfahren zu Ihrer Herstellung und Ihre Verwendung als Arzneimittel
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EP1630163A1 (de) * 2004-08-25 2006-03-01 Boehringer Ingelheim Pharma GmbH & Co.KG Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
EP1632493A1 (de) * 2004-08-25 2006-03-08 Boehringer Ingelheim Pharma GmbH & Co.KG Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
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Also Published As

Publication number Publication date
DE102004058337A1 (de) 2006-06-14
AU2005311308A1 (en) 2006-06-08
MY147459A (en) 2012-12-14
ES2548680T3 (es) 2015-10-20
CY1113625T1 (el) 2016-06-22
SG158848A1 (en) 2010-02-26
EP1819706B1 (de) 2012-09-19
EP2436685B1 (de) 2015-07-01
CN102093361A (zh) 2011-06-15
KR20120136414A (ko) 2012-12-18
AR053100A1 (es) 2007-04-25
PE20061061A1 (es) 2006-11-10
CN101065381B (zh) 2011-03-30
CN102070637A (zh) 2011-05-25
HK1158199A1 (en) 2012-07-13
WO2006058876A1 (de) 2006-06-08
US7626019B2 (en) 2009-12-01
US20070213531A1 (en) 2007-09-13
BRPI0518601A2 (pt) 2008-11-25
HK1113489A1 (en) 2008-10-03
US20070213530A1 (en) 2007-09-13
PT1819706E (pt) 2012-12-06
CA2588857A1 (en) 2006-06-08
NZ556182A (en) 2009-08-28
DK2436685T3 (en) 2015-09-14
CA2588857C (en) 2013-10-08
TWI362391B (en) 2012-04-21
HK1158200A1 (en) 2012-07-13
SI1819706T1 (sl) 2013-01-31
KR101362131B1 (ko) 2014-02-19
JP2008521861A (ja) 2008-06-26
EA200701164A1 (ru) 2007-12-28
SG141461A1 (en) 2008-04-28
US7238807B2 (en) 2007-07-03
UA89390C2 (ru) 2010-01-25
CN102070637B (zh) 2012-09-26
EP1819706A1 (de) 2007-08-22
CN101065381A (zh) 2007-10-31
IL183568A0 (en) 2007-09-20
US20070213528A1 (en) 2007-09-13
ME01470B (me) 2014-04-20
KR101395591B1 (ko) 2014-05-16
ZA200703368B (en) 2008-09-25
US20070213534A1 (en) 2007-09-13
KR20070092252A (ko) 2007-09-12
HUE027689T2 (hu) 2021-12-28
US20070213529A1 (en) 2007-09-13
CN102093361B (zh) 2014-05-07
AU2005311308B2 (en) 2012-04-12
PE20090488A1 (es) 2009-05-27
JP5164574B2 (ja) 2013-03-21
US20060122393A1 (en) 2006-06-08
UY29233A1 (es) 2006-07-31
DK1819706T3 (da) 2013-01-02
US20070208027A1 (en) 2007-09-06
RS52533B (sr) 2013-04-30
PL1819706T3 (pl) 2013-03-29
US20070219369A1 (en) 2007-09-20
TW200628471A (en) 2006-08-16
PL2436685T3 (pl) 2015-11-30
IL183568A (en) 2015-02-26
USRE43115E1 (en) 2012-01-17
EP2436685A1 (de) 2012-04-04
ES2395829T3 (es) 2013-02-15
MX2007006549A (es) 2007-06-18
NO20072283L (no) 2007-06-28
EA012624B1 (ru) 2009-10-30
HRP20120980T1 (hr) 2012-12-31

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