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WO2002055710A3 - Regulation of human purple acid phosphatase - Google Patents

Regulation of human purple acid phosphatase Download PDF

Info

Publication number
WO2002055710A3
WO2002055710A3 PCT/EP2002/000058 EP0200058W WO02055710A3 WO 2002055710 A3 WO2002055710 A3 WO 2002055710A3 EP 0200058 W EP0200058 W EP 0200058W WO 02055710 A3 WO02055710 A3 WO 02055710A3
Authority
WO
WIPO (PCT)
Prior art keywords
human
acid phosphatase
purple acid
regulation
reagents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2002/000058
Other languages
French (fr)
Other versions
WO2002055710A2 (en
Inventor
Yonghong Xiao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of WO2002055710A2 publication Critical patent/WO2002055710A2/en
Publication of WO2002055710A3 publication Critical patent/WO2002055710A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/03002—Acid phosphatase (3.1.3.2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Reagents that regulate human purple acid phosphatase and reagents which bind to human purple acid phosphatase gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, obesity, diabetes, cardiovascular disorders, CNS disorders, and cancer.
PCT/EP2002/000058 2001-01-11 2002-01-07 Regulation of human purple acid phosphatase Ceased WO2002055710A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US26067101P 2001-01-11 2001-01-11
US60/260,671 2001-01-11
US30761601P 2001-07-26 2001-07-26
US60/307,616 2001-07-26

Publications (2)

Publication Number Publication Date
WO2002055710A2 WO2002055710A2 (en) 2002-07-18
WO2002055710A3 true WO2002055710A3 (en) 2003-04-24

Family

ID=26948131

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/000058 Ceased WO2002055710A2 (en) 2001-01-11 2002-01-07 Regulation of human purple acid phosphatase

Country Status (1)

Country Link
WO (1) WO2002055710A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1791432A4 (en) * 2004-09-09 2010-07-07 Gen Hospital Corp MODULATION OF PHOSPHATASE ACTIVITY IN CARDIAC CELLS
CA2677452A1 (en) * 2007-02-14 2008-08-21 Karolinska Innovations Ab Compositions for increasing body weight, use and methods

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000031289A1 (en) * 1998-11-19 2000-06-02 Pharmacia Ab Use of activated trap for screening for specific inhibitor of trap and method for aiding in the identification of a compound for use in the treatment of diseases or degenerative conditions resulting in increased bone resorption
WO2002024924A2 (en) * 2000-09-21 2002-03-28 Incyte Genomics, Inc. Protein phosphatases

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000031289A1 (en) * 1998-11-19 2000-06-02 Pharmacia Ab Use of activated trap for screening for specific inhibitor of trap and method for aiding in the identification of a compound for use in the treatment of diseases or degenerative conditions resulting in increased bone resorption
WO2002024924A2 (en) * 2000-09-21 2002-03-28 Incyte Genomics, Inc. Protein phosphatases

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 1 January 1998 (1998-01-01), MCMURRAY, A.A:: "F21A3.2 protein", XP002221134, retrieved from EBI Database accession no. O17825 *
MARSHALL ET AL: "Recombinant Human and Mouse Purple Acid Phosphatases: Expression and Characterization", ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, NEW YORK, US, US, vol. 345, no. 2, 15 September 1997 (1997-09-15), pages 230 - 236, XP002207501, ISSN: 0003-9861 *

Also Published As

Publication number Publication date
WO2002055710A2 (en) 2002-07-18

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