UA82877C2 - Cgrp receptor antagonists - Google Patents

Cgrp receptor antagonists Download PDF

Info

Publication number: UA82877C2
Authority: UA; Ukraine
Prior art keywords: alkyl; compound; solution; compounds; mmol
Prior art date: 2003-04-15

Application number

UAA200510685A

Other languages

English (en)

Ukrainian (uk)

Inventor

Christopher S Burgey

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-04-15

Filing date

2004-09-04

Publication date

2008-05-26

2004-09-04 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

2008-05-26 Publication of UA82877C2 publication Critical patent/UA82877C2/uk

Links

108010078311 Calcitonin Gene-Related Peptide Receptors Proteins 0.000 title abstract 2
229940044551 receptor antagonist Drugs 0.000 title description 4
239000002464 receptor antagonist Substances 0.000 title description 4
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238000002360 preparation method Methods 0.000 claims description 13
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General Chemical & Material Sciences (AREA)
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Emergency Medicine (AREA)
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Urology & Nephrology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

UAA200510685A 2003-04-15 2004-09-04 Cgrp receptor antagonists UA82877C2 (en)

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US46308903P	2003-04-15	2003-04-15
US51035203P	2003-10-10	2003-10-10
PCT/US2004/010851 WO2004092166A2 (fr)	2003-04-15	2004-04-09	Antagonistes des recepteurs cgrp

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US (6)	US6953790B2 (fr)
EP (2)	EP1638969B1 (fr)
JP (1)	JP3967766B2 (fr)
KR (1)	KR100769030B1 (fr)
CN (1)	CN100384843C (fr)
AR (1)	AR045887A1 (fr)
AT (1)	ATE413400T1 (fr)
AU (1)	AU2004230926B2 (fr)
BR (1)	BRPI0409601A (fr)
CA (1)	CA2522220C (fr)
CL (1)	CL2004000788A1 (fr)
CO (1)	CO5640130A2 (fr)
CY (1)	CY1108714T1 (fr)
DE (1)	DE602004017608D1 (fr)
DK (1)	DK1638969T3 (fr)
EC (1)	ECSP056097A (fr)
ES (1)	ES2314417T3 (fr)
HR (1)	HRP20080666T3 (fr)
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JO (1)	JO2355B1 (fr)
MA (1)	MA27728A1 (fr)
MX (1)	MXPA05011166A (fr)
NO (1)	NO327655B1 (fr)
NZ (1)	NZ543357A (fr)
PE (1)	PE20050020A1 (fr)
PL (1)	PL1638969T3 (fr)
PT (1)	PT1638969E (fr)
RU (1)	RU2308458C2 (fr)
SI (1)	SI1638969T1 (fr)
TW (1)	TWI314931B (fr)
UA (1)	UA82877C2 (fr)
WO (2)	WO2004092168A1 (fr)

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HUE032132T2 (en) *	2002-06-05	2017-09-28	Bristol Myers Squibb Co	Peptide receptor related to calcitonin gene
DE602004027021D1 (de) *	2003-04-15	2010-06-17	Merck Sharp & Dohme	Cgrp-rezeptorantagonisten
GB0310881D0 (en) *	2003-05-12	2003-06-18	Merck Sharp & Dohme	Pharmaceutical formulation
WO2005000807A2 (fr) *	2003-06-26	2005-01-06	Merck & Co., Inc.	Antagonistes du recepteur cgrp de benzodiazepine
EP1641423B1 (fr) *	2003-06-26	2010-03-17	Merck Sharp & Dohme Corp.	Benzodiazepines antagonistes du recepteur cgrp
TW200524601A (en)	2003-12-05	2005-08-01	Bristol Myers Squibb Co	Heterocyclic anti-migraine agents
CN101124217A (zh) *	2004-01-29	2008-02-13	默克公司	Cgrp受体拮抗剂
US20090209491A1 (en) *	2004-02-23	2009-08-20	Trustees Of Tufts College	Lactams as conformationally constrained peptidomimetic inhibitors
TW200533398A (en)	2004-03-29	2005-10-16	Bristol Myers Squibb Co	Novel therapeutic agents for the treatment of migraine
JP2008515895A (ja) *	2004-10-07	2008-05-15	メルクエンドカムパニーインコーポレーテッド	Ｃｇｒｐ受容体拮抗薬
JP2008516957A (ja) *	2004-10-14	2008-05-22	メルクエンドカムパニーインコーポレーテッド	Ｃｇｒｐ受容体拮抗薬
WO2006047196A2 (fr) *	2004-10-22	2006-05-04	Merck & Co., Inc.	Antagonistes de recepteurs cgrp
US7384931B2 (en) *	2004-11-03	2008-06-10	Bristol-Myers Squibb Company	Constrained compounds as CGRP-receptor antagonists
US7384930B2 (en) *	2004-11-03	2008-06-10	Bristol-Myers Squibb Company	Constrained compounds as CGRP-receptor antagonists
US7449586B2 (en)	2004-12-03	2008-11-11	Bristol-Myers Squibb Company	Processes for the preparation of CGRP-receptor antagonists and intermediates thereof
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EP1861399B1 (fr) *	2005-03-14	2011-12-14	Merck Sharp & Dohme Corp.	Antagonistes du recepteur du cgrp
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WO2007120592A1 (fr) *	2006-04-10	2007-10-25	Merck & Co., Inc.	Sel antagoniste de cgrp
EP2007731B1 (fr)	2006-04-10	2009-07-22	Merck & Co., Inc.	Procédé de préparation d'un intermédiaire d'antagoniste du peptide cgrp de caprolactame
DE602007002182D1 (de) *	2006-04-10	2009-10-08	Merck & Co Inc	Verfahren zur herstellung von cgrp-antagonisten
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Publication number	Publication date
US20040229861A1 (en)	2004-11-18
ES2314417T3 (es)	2009-03-16
US6953790B2 (en)	2005-10-11
CO5640130A2 (es)	2006-05-31
CY1108714T1 (el)	2014-04-09
NO327655B1 (no)	2009-09-07
KR100769030B1 (ko)	2007-10-22
CL2004000788A1 (es)	2005-02-25
US7772224B2 (en)	2010-08-10
AU2004230926A1 (en)	2004-10-28
NO20055375L (no)	2005-11-14
SI1638969T1 (sl)	2009-02-28
KR20050121734A (ko)	2005-12-27
JP2006523697A (ja)	2006-10-19
IS8055A (is)	2005-09-29
CN100384843C (zh)	2008-04-30
ECSP056097A (es)	2006-03-01
CA2522220C (fr)	2009-06-23
DK1638969T3 (da)	2009-01-26
WO2004092166A3 (fr)	2005-01-20
BRPI0409601A (pt)	2006-04-18
US20080280857A1 (en)	2008-11-13
HK1090922A1 (en)	2007-01-05
HRP20080666T3 (en)	2009-01-31
US7235545B2 (en)	2007-06-26
PT1638969E (pt)	2009-01-16
WO2004092166A2 (fr)	2004-10-28
PL1638969T3 (pl)	2009-04-30
ATE413400T1 (de)	2008-11-15
NZ543357A (en)	2008-08-29
US20090192139A1 (en)	2009-07-30
US20050256098A1 (en)	2005-11-17
RU2308458C2 (ru)	2007-10-20
WO2004092168A1 (fr)	2004-10-28
EP1638969A2 (fr)	2006-03-29
CN1802376A (zh)	2006-07-12
TWI314931B (en)	2009-09-21
EP2039694B1 (fr)	2014-03-26
TW200505903A (en)	2005-02-16
JP3967766B2 (ja)	2007-08-29
DE602004017608D1 (de)	2008-12-18
AU2004230926B2 (en)	2008-07-17
US20070225272A1 (en)	2007-09-27
AR045887A1 (es)	2005-11-16
IS2759B (is)	2011-10-15
MA27728A1 (fr)	2006-01-02
MXPA05011166A (es)	2005-12-14
EP1638969B1 (fr)	2008-11-05
US7452903B2 (en)	2008-11-18
US7534784B2 (en)	2009-05-19
PE20050020A1 (es)	2005-02-18
JO2355B1 (en)	2006-12-12
US20100298303A1 (en)	2010-11-25
US7893052B2 (en)	2011-02-22
CA2522220A1 (fr)	2004-10-28
EP2039694A1 (fr)	2009-03-25
RU2005135440A (ru)	2006-03-20

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