[go: up one dir, main page]

UA8027A1 - Спосіб одержання похідних дігідропірідіна - Google Patents

Спосіб одержання похідних дігідропірідіна

Info

Publication number
UA8027A1
UA8027A1 UA2630202A UA2630202A UA8027A1 UA 8027 A1 UA8027 A1 UA 8027A1 UA 2630202 A UA2630202 A UA 2630202A UA 2630202 A UA2630202 A UA 2630202A UA 8027 A1 UA8027 A1 UA 8027A1
Authority
UA
Ukraine
Prior art keywords
preparation
alkyl
alkoxy group
dihydropyridine derivatives
hydrogen
Prior art date
Application number
UA2630202A
Other languages
English (en)
Russian (ru)
Inventor
Hойманн Петер
Original Assignee
"Сандос АГ"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by "Сандос АГ" filed Critical "Сандос АГ"
Publication of UA8027A1 publication Critical patent/UA8027A1/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Спосіб одержання похідних дигідропіридину загальної формули , де R1 - водень, С1-С3-алкіл; R2 і R5 - С1-С5-алкіл; R3 - С1-С4-алкіл, С1-С4-алкоксигрупа, С1-С6-алкоксиетоксигрупа; R4 - С1-С4-алкоксигрупа; R6 - водень, хлор або С1-С4-алкоксигрупа; Х-кисень або сірка. Похідне 2,1,3-бенз(тіо)оксадіазолу загальної формули , де Х и R6 мають зазначені значення, спочатку обробляються сполуки формули R5СОСН2СО R4, де R4 і R5 мають зазначені значення, а потім ефіром =С1-С3-алкіламінокротонової кислоти.
UA2630202A 1977-06-20 1978-06-20 Спосіб одержання похідних дігідропірідіна UA8027A1 (uk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH752077 1977-06-20

Publications (1)

Publication Number Publication Date
UA8027A1 true UA8027A1 (uk) 1995-12-26

Family

ID=4326429

Family Applications (2)

Application Number Title Priority Date Filing Date
UA2630202A UA8027A1 (uk) 1977-06-20 1978-06-20 Спосіб одержання похідних дігідропірідіна
UA3651891A UA8014A1 (uk) 1977-06-20 1978-06-20 Спосіб отримання похідних 1,4-дігідропірідину

Family Applications After (1)

Application Number Title Priority Date Filing Date
UA3651891A UA8014A1 (uk) 1977-06-20 1978-06-20 Спосіб отримання похідних 1,4-дігідропірідину

Country Status (4)

Country Link
US (1) US4567271A (uk)
SU (2) SU1122223A3 (uk)
UA (2) UA8027A1 (uk)
ZA (1) ZA783516B (uk)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8503262A (nl) * 1984-12-10 1986-07-01 Sandoz Ag 1,4-dihydropyridinederivaten, werkwijze voor het bereiden van deze derivaten en farmaceutische preparaten die ze bevatten.
WO2008106659A2 (en) * 2007-03-01 2008-09-04 Memory Pharmaceuticals Corporation Methods of treating bipolar disorder and memory and/or cognitive impairment associated therewith
CN102285978B (zh) * 2011-06-27 2016-01-06 合肥华方医药科技有限公司 一种制备含有苯并呋咱环类抗高血压药物的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4466972A (en) * 1977-06-20 1984-08-21 Sandoz Ltd. Benzoxadiazoles and benzothiadiazoles, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
SU1122223A3 (ru) 1984-10-30
ZA783516B (en) 1980-03-26
UA8014A1 (uk) 1995-12-26
SU1205762A3 (ru) 1986-01-15
US4567271A (en) 1986-01-28

Similar Documents

Publication Publication Date Title
DE3069408D1 (en) 5-oxo- and 5-thioxoproline derivatives, process for their production and pharmaceutical compositions containing them
JPS559058A (en) 1-(3-mercapto-2-methylpropanoyl)prolyl amino acid derivative
ES8603501A1 (es) Un procedimiento para preparar un derivado de 1,8-naftiridina
MY107474A (en) Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents.
ES479166A1 (es) Un procedimiento para la preparacion de acido 7&-metoxi-7b-(4-metilen sustituido 1,3-ditietan-2il) carboxamido-3-hetero-ciclotiometil-3-cefem-4-carboxilico.
YU86988A (en) Process for obtaining new beta-d-phenyl-thioxylozides
ES468408A1 (es) Procedimiento para la preparacion de 1,2,3-tiadiazol-3-in-5-iliden-ureas.
UA8027A1 (uk) Спосіб одержання похідних дігідропірідіна
ES2129073T3 (es) Derivados del acido 4-fenilcarbamoil-3-isoxazol-carboxilico con actividad antiinflamatoria.
NO940265L (no) Fremgangsmaate ved fremstilling av svovelholdige karboksyl-syreamider
RO92245B (ro) Procedeu pentru prepararea unor derivati de 1,6-naftiridina
ZA802257B (en) Production of reducing gas for furnace injection
JPS5430183A (en) 3,4-dihydrocarbostyril derivative
ES459079A1 (es) Un procedimiento para la preparacion de esteres del acido crisantemico.
AR246511A1 (es) Acido 2-azabiciclo (2.2.1)hept-5-eno-2-acetico y derivados del mismo, procedimiento para su preparacion y procedimiento para preparar n-fosfonometilglicina con los mismos.
ES8606841A1 (es) Procedimiento para la preparacion de derivados de carboci- clina
AU543519B2 (en) New peptide amides and process for their manufacture
ES466053A1 (es) Un procedimiento de preparacion de acidos amino-espiro(oxa- (0 tia)cicloalcanopenam)-carboxilicos.
IE791332L (en) Oxazolidine derivatives
GB1277620A (en) Electrodes for electric arc furnaces
ES468820A1 (es) Procedimiento para la preparacion de derivados de 1,2,3,- tiadiazolin-2-ida.
JPS5226361A (en) Process for refining of harmful gases
ES441938A1 (es) Procedimiento para la preparacion de nuevos arilisotiociana-tos.
ES462110A1 (es) Procedimiento para la preparacion de tiolactona de n-6-clo- ronicotinoil-d,1-homocisteina.
ES472703A1 (es) Un procedimiento para preparar derivados del acido oxanilico