[go: up one dir, main page]

TR200002692T2 - Aerosol haline getirilen aktif maddenin verilmesi. - Google Patents

Aerosol haline getirilen aktif maddenin verilmesi.

Info

Publication number
TR200002692T2
TR200002692T2 TR2000/02692T TR200002692T TR200002692T2 TR 200002692 T2 TR200002692 T2 TR 200002692T2 TR 2000/02692 T TR2000/02692 T TR 2000/02692T TR 200002692 T TR200002692 T TR 200002692T TR 200002692 T2 TR200002692 T2 TR 200002692T2
Authority
TR
Turkey
Prior art keywords
active substance
administration
per minute
aerosolized active
liters per
Prior art date
Application number
TR2000/02692T
Other languages
English (en)
Inventor
Clark Andrew
H. Foulds George
Original Assignee
Inhale Therapeutic Systems, Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inhale Therapeutic Systems, Inc filed Critical Inhale Therapeutic Systems, Inc
Publication of TR200002692T2 publication Critical patent/TR200002692T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Bu bulus, bir insan hastanin akcigerlerine bir aktif maddenin verilmesine yönelik metodlar ve düzeneklere yönelmistir. Aktif madde formülasyonu kuru toz halinde bulunabilir, nebulize bir halde olabilir, veya bir itici madde ile karisim halinde bulunabilir. Aktif madde formülasyonu, bir hastaya dakikada 17 litreden daha az olan bir solunum akis orani ile verilir. Aktif maddenin biyoelverisliliginin, dakikada 17 litre veya daha fazla olan solunum akis oranlarina kiyasla, bu akis oranlarinda arttigi görülmüstür.
TR2000/02692T 1998-03-16 1999-03-11 Aerosol haline getirilen aktif maddenin verilmesi. TR200002692T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7821498P 1998-03-16 1998-03-16
US7821298P 1998-03-16 1998-03-16

Publications (1)

Publication Number Publication Date
TR200002692T2 true TR200002692T2 (tr) 2001-02-21

Family

ID=26760240

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/02692T TR200002692T2 (tr) 1998-03-16 1999-03-11 Aerosol haline getirilen aktif maddenin verilmesi.

Country Status (42)

Country Link
US (2) US6655379B2 (tr)
EP (1) EP1066074A1 (tr)
JP (1) JP4195191B2 (tr)
KR (1) KR100620338B1 (tr)
CN (1) CN1292714B (tr)
AP (1) AP1342A (tr)
AR (1) AR018161A1 (tr)
AU (1) AU750539B2 (tr)
BG (1) BG65091B1 (tr)
BR (1) BR9908771A (tr)
CA (1) CA2322045C (tr)
CO (1) CO5060522A1 (tr)
DZ (1) DZ2744A1 (tr)
EA (1) EA003196B1 (tr)
EE (1) EE200000546A (tr)
GE (1) GEP20043260B (tr)
HN (1) HN1999000028A (tr)
HR (2) HRP20000608A2 (tr)
HU (1) HUP0100848A3 (tr)
ID (1) ID26237A (tr)
IL (1) IL138153A0 (tr)
IS (1) IS5595A (tr)
LT (1) LT4818B (tr)
LV (1) LV12586B (tr)
MA (1) MA26033A1 (tr)
MY (1) MY131803A (tr)
NO (1) NO20004627L (tr)
NZ (1) NZ506289A (tr)
OA (1) OA11529A (tr)
PA (1) PA8468901A1 (tr)
PE (1) PE20000346A1 (tr)
PL (1) PL343276A1 (tr)
RO (1) RO121834B1 (tr)
SA (1) SA99200198B1 (tr)
SI (1) SI20413A (tr)
SK (1) SK13632000A3 (tr)
TN (1) TNSN99038A1 (tr)
TR (1) TR200002692T2 (tr)
TW (1) TWI228998B (tr)
UY (1) UY25432A1 (tr)
WO (1) WO1999047196A1 (tr)
YU (1) YU56600A (tr)

Families Citing this family (135)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100291620B1 (ko) 1992-09-29 2001-10-24 추후제출 부갑상선호르몬의활성단편의폐를통한전달방법
ATE264096T1 (de) 1994-03-07 2004-04-15 Nektar Therapeutics Verfahren und mittel zur verabreichung von insulin über die lunge
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
US6309671B1 (en) * 1995-04-14 2001-10-30 Inhale Therapeutic Systems Stable glassy state powder formulations
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
GB9807232D0 (en) * 1998-04-03 1998-06-03 Univ Cardiff Aerosol composition
UA73924C2 (en) * 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
GB2353222B (en) * 1999-06-23 2001-09-19 Cambridge Consultants Inhalers
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6606992B1 (en) 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
US7305986B1 (en) * 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US7464706B2 (en) 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
JP4711520B2 (ja) * 2000-03-21 2011-06-29 日本ケミカルリサーチ株式会社 生理活性ペプチド含有粉末
PE20011227A1 (es) * 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
CA2382133C (en) 2000-05-10 2010-11-23 Alliance Pharmaceutical Corporation Phospholipid-based powders for drug delivery
EP1296651B2 (en) 2000-06-27 2019-07-17 Vectura Limited Method of making particles for use in a pharmaceutical composition
US6339107B1 (en) 2000-08-02 2002-01-15 Syntex (U.S.A.) Llc Methods for treatment of Emphysema using 13-cis retinoic acid
EP1935869A1 (en) 2000-10-02 2008-06-25 F. Hoffmann-La Roche Ag Retinoids for the treatment of emphysema
US7049283B2 (en) 2000-12-06 2006-05-23 Novartis Ag Pharmaceutical compositions for the oral delivery of pharmacologically active agents
US6782887B2 (en) * 2001-01-12 2004-08-31 Becton, Dickinson And Company Medicament respiratory delivery device and cartridge
ES2431634T3 (es) 2001-06-20 2013-11-27 Novartis Ag Dispositivo de administración de aerosol
GB2380946A (en) * 2001-08-31 2003-04-23 Medic Aid Ltd Nebuliser arrangement
WO2003053411A1 (en) 2001-12-19 2003-07-03 Nektar Therapeutics Pulmonary delivery of aminoglycosides
AU2003220125B2 (en) 2002-03-20 2006-06-15 Mannkind Corporation Inhalation apparatus
ES2633913T3 (es) 2002-03-22 2017-09-26 Clinical Designs Limited Fijación de cartucho
UA80123C2 (en) * 2002-04-09 2007-08-27 Boehringer Ingelheim Pharma Inhalation kit comprising inhalable powder of tiotropium
US7185651B2 (en) 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
WO2004054606A1 (en) * 2002-12-13 2004-07-01 Pfizer Products Inc. Method of decreasing hepatic glucose output in diabetic patients
US20050236296A1 (en) * 2002-12-30 2005-10-27 Nektar Therapeutics (Formerly Inhale Therapeutic Systems, Inc.) Carry case for aerosolization apparatus
GB0304000D0 (en) 2003-02-21 2003-03-26 Clinical Designs Ltd Dispenser
ES2383367T5 (es) * 2003-04-09 2021-03-31 Novartis Ag Aparato de pulverización en forma de aerosol con protección de entrada de aire
DK3549936T3 (da) 2003-04-11 2021-07-12 Ptc Therapeutics Inc 1,2,4-oxadiazol-benzoesyreforbindelse og dens anvendelse til nonsense-undertrykkelse og behandlingen af sygdom
GB0313604D0 (en) * 2003-06-12 2003-07-16 Britannia Pharmaceuticals Ltd Delivery device for powdered medicament
JP2007521232A (ja) 2003-08-08 2007-08-02 アブジェニックス・インコーポレーテッド 副甲状腺ホルモン（ｐｔｈ）に対する抗体およびその使用
US7318925B2 (en) * 2003-08-08 2008-01-15 Amgen Fremont, Inc. Methods of use for antibodies against parathyroid hormone
EP2065383A1 (en) 2003-11-19 2009-06-03 Signal Pharmaceuticals, Inc. Indazole compounds and methods of use thereof as protein kinase inhibitors
GB0327112D0 (en) 2003-11-21 2003-12-24 Clincial Designs Ltd Dispenser and reservoir
GB0328859D0 (en) 2003-12-12 2004-01-14 Clinical Designs Ltd Dispenser and counter
WO2005065756A2 (en) 2003-12-30 2005-07-21 Oriel Therapeutics, Inc. Dry powder nebulizers and associated methods of dispensing dry powders
PL1786784T3 (pl) 2004-08-20 2011-04-29 Mannkind Corp Kataliza syntezy diketopiperazyn
EP2314298B1 (en) 2004-08-23 2015-05-27 MannKind Corporation Microparticles comprising diketopiperazine salts for drug delivery
KR101241434B1 (ko) * 2004-09-10 2013-03-12 파마오리진 에이피에스 국소 기관, 기관지 또는 폐포의 출혈 또는 객혈의 치료방법
GB0425518D0 (en) 2004-11-19 2004-12-22 Clinical Designs Ltd Substance source
US7827983B2 (en) * 2004-12-20 2010-11-09 Hewlett-Packard Development Company, L.P. Method for making a pharmaceutically active ingredient abuse-prevention device
GB0428204D0 (en) * 2004-12-23 2005-01-26 Clinical Designs Ltd Medicament container
US20160345631A1 (en) 2005-07-19 2016-12-01 James Monsees Portable devices for generating an inhalable vapor
US9675109B2 (en) 2005-07-19 2017-06-13 J. T. International Sa Method and system for vaporization of a substance
CA2615718A1 (en) 2005-07-22 2007-02-01 Amgen Inc. Aniline sulfonamide derivatives and their uses
GB0518400D0 (en) 2005-09-09 2005-10-19 Clinical Designs Ltd Dispenser
AU2006290870B2 (en) 2005-09-14 2013-02-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
US7973005B2 (en) 2006-02-09 2011-07-05 Kamada Ltd. Alpha-1 antitrypsin for treating exacerbation episodes of pulmonary diseases
DK1986679T3 (da) 2006-02-22 2017-11-20 Mannkind Corp Fremgangsmåde til forbedring af mikropartiklers farmaceutiske egenskaber omfattende diketopiperazin og et aktivt indholdsstof
ATE476418T1 (de) 2006-06-08 2010-08-15 Amgen Inc Benzamidderivate und assoziierte verwendungen
TW200808695A (en) 2006-06-08 2008-02-16 Amgen Inc Benzamide derivatives and uses related thereto
EP2051977A2 (en) 2006-07-20 2009-04-29 Amgen Inc. SUBSTITUTED AZOLE AROMATIC HETEROCYCLES AS INHIBITORS OF LLbeta-HSD-1
AU2007343726A1 (en) 2006-12-26 2008-07-24 Amgen Inc. N-cyclohexyl benzamides and benzeneacetamides as inhibitors of 11-beta-hydroxysteroid dehydrogenases
US8991402B2 (en) 2007-12-18 2015-03-31 Pax Labs, Inc. Aerosol devices and methods for inhaling a substance and uses thereof
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
CN103252007B (zh) 2008-06-13 2016-06-22 曼金德公司 干粉吸入器和用于药物输送的系统
JP5479465B2 (ja) 2008-06-20 2014-04-23 マンカインド コーポレイション 吸入努力をリアルタイムにプロファイルする対話式機器および方法
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
GB0904059D0 (en) 2009-03-10 2009-04-22 Euro Celtique Sa Counter
GB0904040D0 (en) 2009-03-10 2009-04-22 Euro Celtique Sa Counter
EP2676695A3 (en) 2009-03-11 2017-03-01 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
KR101875969B1 (ko) 2009-06-12 2018-07-06 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
USD655411S1 (en) 2009-12-31 2012-03-06 Remot Medical Innovation, LLC Endotracheal tube adaptor
US9084864B1 (en) 2010-03-04 2015-07-21 Barthel LLC Adaptor for breathing tube and method
US8974771B2 (en) * 2010-03-09 2015-03-10 Penn-Century, Inc. Apparatus and method for aerosol delivery to the lungs or other locations of the body
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
US9757528B2 (en) 2010-08-23 2017-09-12 Darren Rubin Nebulizer having different negative pressure threshold settings
EP2608829A4 (en) 2010-08-23 2015-11-18 Darren Rubin SYSTEMS AND METHODS FOR AEROSOL SUPPLY WITH AIRFLOW REGULATION
USD679008S1 (en) 2011-01-07 2013-03-26 Remot Medical Innovation, LLC Endotracheal tube adaptor
CN105667994B (zh) 2011-04-01 2018-04-06 曼金德公司 用于药物药盒的泡罩包装
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
CA2845090C (en) 2011-08-16 2023-01-31 Ploom, Inc. Low temperature electronic vaporization device and methods
WO2013063160A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
EP2758065B1 (en) 2011-12-30 2021-06-23 Grifols, S.A. Alpha1-proteinase inhibitor for use in delaying the onset or progression of pulmonary exacerbations
FR2985909B1 (fr) * 2012-01-20 2014-08-08 Diffusion Tech Francaise Sarl Dispositif de nebulisation pour aerosols medicaux
EP3421042B1 (en) 2012-03-07 2024-04-17 Beyond Air Ltd Inhalation of nitric oxide for treating respiratory diseases
EP2834635A4 (en) * 2012-04-03 2015-09-02 Smiths Medical Asd Inc COMPOSITIONS WITH A HEPARINE ACCUMULATIVE AND METHOD THEREFOR
SG11201500218VA (en) 2012-07-12 2015-03-30 Mannkind Corp Dry powder drug delivery systems and methods
US10517530B2 (en) 2012-08-28 2019-12-31 Juul Labs, Inc. Methods and devices for delivering and monitoring of tobacco, nicotine, or other substances
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
US10034988B2 (en) 2012-11-28 2018-07-31 Fontem Holdings I B.V. Methods and devices for compound delivery
EP2970149B1 (en) 2013-03-15 2019-08-21 MannKind Corporation Microcrystalline diketopiperazine compositions and methods
US10279934B2 (en) 2013-03-15 2019-05-07 Juul Labs, Inc. Fillable vaporizer cartridge and method of filling
US10653180B2 (en) 2013-06-14 2020-05-19 Juul Labs, Inc. Multiple heating elements with separate vaporizable materials in an electric vaporization device
ES2999088T3 (en) 2013-05-06 2025-02-24 Juul Labs Inc Nicotine salt formulations for aerosol devices and methods thereof
CN105451716A (zh) 2013-07-18 2016-03-30 曼金德公司 热稳定性干粉药物组合物和方法
WO2015021064A1 (en) 2013-08-05 2015-02-12 Mannkind Corporation Insufflation apparatus and methods
WO2015042412A1 (en) 2013-09-20 2015-03-26 E-Nicotine Technology. Inc. Devices and methods for modifying delivery devices
IL295735B2 (en) 2013-12-05 2024-04-01 Juul Labs Inc Nicotine liquid formulations for aerosol devices and methods thereof
US10058129B2 (en) 2013-12-23 2018-08-28 Juul Labs, Inc. Vaporization device systems and methods
US9549573B2 (en) 2013-12-23 2017-01-24 Pax Labs, Inc. Vaporization device systems and methods
PL3504991T3 (pl) 2013-12-23 2021-08-16 Juul Labs International Inc. Systemy urządzeń do odparowywania
US20160366947A1 (en) 2013-12-23 2016-12-22 James Monsees Vaporizer apparatus
US10159282B2 (en) 2013-12-23 2018-12-25 Juul Labs, Inc. Cartridge for use with a vaporizer device
USD825102S1 (en) 2016-07-28 2018-08-07 Juul Labs, Inc. Vaporizer device with cartridge
US10076139B2 (en) 2013-12-23 2018-09-18 Juul Labs, Inc. Vaporizer apparatus
USD842536S1 (en) 2016-07-28 2019-03-05 Juul Labs, Inc. Vaporizer cartridge
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
CN106170313B (zh) 2014-04-28 2020-11-10 菲利普莫里斯生产公司 带香味尼古丁粉末吸入器
HUE045841T2 (hu) 2014-04-28 2020-01-28 Philip Morris Products Sa Nikotinpor-inhalátor
CA2948851A1 (en) 2014-05-16 2015-11-19 Pax Labs, Inc. Systems and methods for aerosolizing a smokeable material
US10471222B2 (en) * 2014-07-01 2019-11-12 Dance Biopharm Inc. Aerosolization system with flow restrictor and feedback device
US11273271B2 (en) 2014-07-01 2022-03-15 Aerami Therapeutics, Inc. Aerosolization system with flow restrictor and feedback device
US10857313B2 (en) * 2014-07-01 2020-12-08 Aerami Therapeutics, Inc. Liquid nebulization systems and methods
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
CA2965759C (en) 2014-10-31 2023-12-12 Glaxosmithkline Intellectual Property Development Limited Powdered polypeptides with decreased disulfide impurities comprising divalent cationic materials
EP4464356A3 (en) 2014-12-05 2025-01-08 Juul Labs, Inc. Calibrated dose control
EP3393562B1 (en) 2015-12-21 2021-08-11 Kindeva Drug Delivery L.P. Medicinal inhalers
JP2019503829A (ja) 2015-12-21 2019-02-14 スリーエム イノベイティブ プロパティズ カンパニー 医療用吸入器で使用するための流れ調整器アセンブリ
JP2019500196A (ja) 2015-12-21 2019-01-10 スリーエム イノベイティブ プロパティズ カンパニー 医療用吸入器で使用するための流れ調整器
DE202017007467U1 (de) 2016-02-11 2021-12-08 Juul Labs, Inc. Befüllbare Verdampferkartusche
EA039727B1 (ru) 2016-02-11 2022-03-04 Джуул Лэбз, Инк. Надежно прикрепляющиеся картриджи для испарительных устройств
US10506829B2 (en) 2016-02-26 2019-12-17 Freelander Innovations USA, LLC System and method for a vaporizer
US10405582B2 (en) 2016-03-10 2019-09-10 Pax Labs, Inc. Vaporization device with lip sensing
USD849996S1 (en) 2016-06-16 2019-05-28 Pax Labs, Inc. Vaporizer cartridge
USD851830S1 (en) 2016-06-23 2019-06-18 Pax Labs, Inc. Combined vaporizer tamp and pick tool
USD848057S1 (en) 2016-06-23 2019-05-07 Pax Labs, Inc. Lid for a vaporizer
USD836541S1 (en) 2016-06-23 2018-12-25 Pax Labs, Inc. Charging device
US11660403B2 (en) 2016-09-22 2023-05-30 Juul Labs, Inc. Leak-resistant vaporizer device
AU2018210671A1 (en) * 2017-01-18 2019-08-08 Medical Developments International Limited Inhaler device for inhalable liquids
USD887632S1 (en) 2017-09-14 2020-06-16 Pax Labs, Inc. Vaporizer cartridge
IL275328B2 (en) 2017-12-12 2024-03-01 Kamada Ltd Methods of inducing immune tolerance and reducing anti-drug antibody response
JP2021521280A (ja) 2018-04-12 2021-08-26 マトルクス セラピューティクス コーポレーション 弾性線維分解を治療するための組成物及び方法
CN113384781B (zh) * 2020-03-11 2024-03-29 李彤 一种egcg雾化系统
CN114712336B (zh) * 2020-12-22 2023-11-07 黄嘉若 一种用于肺部给药的水性气溶胶、制备方法和用途
WO2022155544A1 (en) * 2021-01-15 2022-07-21 Aquestive Therapeutics, Inc. Prodrug compositions and methods of treatment

Family Cites Families (125)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US393869A (en) * 1888-12-04 Inhaler
US957548A (en) * 1909-12-27 1910-05-10 Walter S Doane Inhaler.
US2586215A (en) 1947-10-17 1952-02-19 Hickok Mfg Co Inc Necktie holder
US2587215A (en) * 1949-04-27 1952-02-26 Frank P Priestly Inhalator
US2788784A (en) * 1955-08-23 1957-04-16 Herbert M Birch Means for administering medication orally into the respiratory organs
US3788310A (en) * 1970-03-25 1974-01-29 Westinghouse Electric Corp Flow control apparatus
GB1392945A (en) 1972-08-23 1975-05-07 Fisons Ltd Inhalation device
US4036919A (en) * 1974-06-26 1977-07-19 Inhalation Therapy Equipment, Inc. Nebulizer-humidifier system
US3991304A (en) * 1975-05-19 1976-11-09 Hillsman Dean Respiratory biofeedback and performance evaluation system
US4086918A (en) 1976-02-11 1978-05-02 Chesebrough-Pond's Inc. Inhalation device
US4170228A (en) 1976-11-05 1979-10-09 C. R. Bard, Inc. Variable flow incentive spirometer
US4106503A (en) 1977-03-11 1978-08-15 Richard R. Rosenthal Metering system for stimulating bronchial spasm
GB1598053A (en) 1978-01-31 1981-09-16 Fisons Ltd Pocket inhaler
US4274404A (en) * 1979-04-13 1981-06-23 American Safety Flight Systems, Inc. Oxygen supply system controlled by user exhalation
IT1116047B (it) 1979-04-27 1986-02-10 Sigma Tau Ind Farmaceuti Dispositivo per la rapida inalazione di farmaci in polvere da parte di persone sofferenti di asma
US4284083A (en) 1979-05-29 1981-08-18 Lester Victor E Inhalation incentive device
US4259951A (en) 1979-07-30 1981-04-07 Chesebrough-Pond's Inc. Dual valve for respiratory device
DE3023648A1 (de) 1980-06-24 1982-01-21 Jaeger, Erich, 8700 Würzburg Einrichtung zur untersuchung der atemwege auf reizstoff-ueberempfindlichkeit
US4391283A (en) 1981-03-24 1983-07-05 Whitman Medical Corporation Incentive spirometer
US4366947A (en) * 1981-05-20 1983-01-04 Amp Corporation Calibrated gas-metering apparatus
US4484577A (en) * 1981-07-23 1984-11-27 Key Pharmaceuticals, Inc. Drug delivery method and inhalation device therefor
US4442856A (en) * 1981-08-18 1984-04-17 Puritan-Bennett Oxygen regulator and alarm system for an anesthesia machine
US4533137A (en) 1982-01-19 1985-08-06 Healthscan Inc. Pulmonary training method
US4444202A (en) 1982-03-31 1984-04-24 Howard Rubin Breathing exerciser
ES286422Y (es) 1982-10-08 1986-09-16 Glaxo Group Limited Dispositivo para administrar medicamentos a pacientes
US4778054A (en) 1982-10-08 1988-10-18 Glaxo Group Limited Pack for administering medicaments to patients
US4495944A (en) 1983-02-07 1985-01-29 Trutek Research, Inc. Inhalation therapy apparatus
US5743398A (en) * 1984-05-22 1998-04-28 Southpac Trust International, Inc. Floral wrapper utilizing a breathable packaging material
NZ209900A (en) 1984-10-16 1989-08-29 Univ Auckland Automatic inhaler
US4592348A (en) 1984-12-17 1986-06-03 Waters Iv William C Aerosol inhaler
AT396872B (de) 1985-07-30 1993-12-27 Glaxo Group Ltd Gerät zur verabreichung von medikamenten in pulverform
SE453566B (sv) 1986-03-07 1988-02-15 Draco Ab Anordning vid pulverinhalatorer
US4926852B1 (en) * 1986-06-23 1995-05-23 Univ Johns Hopkins Medication delivery system phase one
ES2051371T3 (es) 1988-10-04 1994-06-16 Univ Johns Hopkins Inhalador de aerosoles.
US5033655A (en) 1989-02-15 1991-07-23 Liquid Molding Systems Inc. Dispensing package for fluid products and the like
US4991745A (en) 1989-04-25 1991-02-12 Liquid Molding Systems, Inc. Dispensing valve with trampoline-like construction
ES2087911T3 (es) 1989-04-28 1996-08-01 Riker Laboratories Inc Dispositivo de inhalacion de polvo seco.
US4955371A (en) 1989-05-08 1990-09-11 Transtech Scientific, Inc. Disposable inhalation activated, aerosol device for pulmonary medicine
US5201308A (en) 1990-02-14 1993-04-13 Newhouse Michael T Powder inhaler
US5042467A (en) 1990-03-28 1991-08-27 Trudell Medical Medication inhaler with fitting having a sonic signalling device
DE4027391A1 (de) 1990-08-30 1992-03-12 Boehringer Ingelheim Kg Treibgasfreies inhalationsgeraet
DE4029183A1 (de) 1990-09-14 1992-03-19 Dieter Kuhn Durchflussregler
GB9021433D0 (en) 1990-10-02 1990-11-14 Atomic Energy Authority Uk Power inhaler
FR2667509B1 (fr) 1990-10-04 1995-08-25 Valois Inhalateur a poudre, dispositif de conditionnement de microdoses de poudre sous forme de bandes adaptees a etre utilisees dans un inhalateur a poudre, et procede de fabrication de ces bandes.
US5042472A (en) 1990-10-15 1991-08-27 Merck & Co., Inc. Powder inhaler device
GB9024760D0 (en) 1990-11-14 1991-01-02 Riker Laboratories Inc Inhalation device and medicament carrier
US5040527A (en) 1990-12-18 1991-08-20 Healthscan Products Inc. Metered dose inhalation unit with slide means
US5392768A (en) * 1991-03-05 1995-02-28 Aradigm Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval
AU651882B2 (en) 1991-05-14 1994-08-04 Visiomed Group Limited Aerosol inhalation device
US6055980A (en) 1991-05-20 2000-05-02 Dura Pharmaceuticals, Inc. Dry powder inhaler
CA2112674C (en) 1991-07-02 2005-10-04 John S. Patton Method and device for delivering aerosolized medicaments
US5337740A (en) 1991-08-01 1994-08-16 New England Pharmaceuticals, Inc. Inhalation devices
US5161524A (en) 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
US6029661A (en) 1991-08-26 2000-02-29 3M Innovative Properties Company Powder dispenser
US5167506A (en) 1991-10-24 1992-12-01 Minnesota Mining And Manufacturing Company Inhalation device training system
US5396884A (en) * 1991-11-15 1995-03-14 Cimco, Inc. High flow rate humidifier with baffle plates
US5409144A (en) 1991-12-06 1995-04-25 Liquid Molding Systems Inc. Dispensing valve for packaging
US5213236A (en) 1991-12-06 1993-05-25 Liquid Molding Systems, Inc. Dispensing valve for packaging
DE4211475A1 (de) 1991-12-14 1993-06-17 Asta Medica Ag Pulverinhalator
US5320094A (en) * 1992-01-10 1994-06-14 The Johns Hopkins University Method of administering insulin
EP0558879B1 (en) 1992-03-04 1997-05-14 Astra Aktiebolag Disposable inhaler
US5639441A (en) * 1992-03-06 1997-06-17 Board Of Regents Of University Of Colorado Methods for fine particle formation
US5785049A (en) 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
US5284133A (en) 1992-07-23 1994-02-08 Armstrong Pharmaceuticals, Inc. Inhalation device with a dose-timer, an actuator mechanism, and patient compliance monitoring means
US5333106A (en) 1992-10-09 1994-07-26 Circadian, Inc. Apparatus and visual display method for training in the power use of aerosol pharmaceutical inhalers
DE4239402A1 (de) 1992-11-24 1994-05-26 Bayer Ag Pulverinhalator
US5364838A (en) 1993-01-29 1994-11-15 Miris Medical Corporation Method of administration of insulin
US5873358A (en) 1993-01-29 1999-02-23 Aradigm Corporation Method of maintaining a diabetic patient's blood glucose level in a desired range
US5743250A (en) 1993-01-29 1998-04-28 Aradigm Corporation Insulin delivery enhanced by coached breathing
US5558085A (en) 1993-01-29 1996-09-24 Aradigm Corporation Intrapulmonary delivery of peptide drugs
US5888477A (en) 1993-01-29 1999-03-30 Aradigm Corporation Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin
US5507277A (en) * 1993-01-29 1996-04-16 Aradigm Corporation Lockout device for controlled release of drug from patient-activateddispenser
US5672581A (en) * 1993-01-29 1997-09-30 Aradigm Corporation Method of administration of insulin
EP0681491B1 (en) 1993-01-29 2000-12-13 Aradigm Corporation Intrapulmonary delivery of hormones
FR2701399B1 (fr) 1993-02-16 1995-03-31 Valois Dispositif portatif de pulvérisation à actionnement déclenché par l'inhalation.
US5437271A (en) 1993-04-06 1995-08-01 Minnesota Mining And Manufacturing Company Deagglomerators for dry powder inhalers
US5349947A (en) * 1993-07-15 1994-09-27 Newhouse Michael T Dry powder inhaler and process that explosively discharges a dose of powder and gas from a soft plastic pillow
US5727546A (en) 1993-08-18 1998-03-17 Fisons Plc Powder inhaler with breath flow regulation valve
US5655520A (en) 1993-08-23 1997-08-12 Howe; Harvey James Flexible valve for administering constant flow rates of medicine from a nebulizer
GB9326574D0 (en) 1993-12-31 1994-03-02 King S College London Dry power inhalers
US6102036A (en) 1994-04-12 2000-08-15 Smoke-Stop Breath activated inhaler
US5483954A (en) 1994-06-10 1996-01-16 Mecikalski; Mark B. Inhaler and medicated package
US5509404A (en) * 1994-07-11 1996-04-23 Aradigm Corporation Intrapulmonary drug delivery within therapeutically relevant inspiratory flow/volume values
US5653223A (en) 1994-09-08 1997-08-05 Pruitt; Michael D. Accurately controlled portable nebulizer
CZ289029B6 (cs) 1994-09-21 2001-10-17 Inhale Therapeutic Systems Způsob aerosolizace práąku, zejména práąkového léku a zařízení k provádění tohoto způsobu
US5993421A (en) * 1994-12-02 1999-11-30 Science Incorporated Medicament dispenser
US5552380A (en) * 1994-12-15 1996-09-03 International Flavors & Fragrances Inc. Perfume uses of phenyl alkanol derivatives
SE9404439D0 (sv) 1994-12-21 1994-12-21 Astra Ab Inhalation device
US5522380A (en) 1995-01-18 1996-06-04 Dwork; Paul Metered dose medication adaptor with improved incentive spirometer
US5568910A (en) * 1995-03-02 1996-10-29 Delmarva Laboratories, Inc. Anesthesia machine
US5513630A (en) 1995-03-08 1996-05-07 Century; Theodore J. Powder dispenser
DE69632533D1 (de) * 1995-03-31 2004-06-24 Aradigm Corp Intrapulmonare verabreichung vom hematopoietischem medikament
US5586550A (en) 1995-08-31 1996-12-24 Fluid Propulsion Technologies, Inc. Apparatus and methods for the delivery of therapeutic liquids to the respiratory system
US5622166A (en) 1995-04-24 1997-04-22 Dura Pharmaceuticals, Inc. Dry powder inhaler delivery system
US5921237A (en) 1995-04-24 1999-07-13 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5654007A (en) 1995-06-07 1997-08-05 Inhale Therapeutic Systems Methods and system for processing dispersible fine powders
US5826571A (en) 1995-06-08 1998-10-27 Innovative Devices, Llc Device for use with metered dose inhalers (MDIS)
GB9513218D0 (en) 1995-06-29 1995-09-06 Fisons Plc Inhalation device and method
DE19523516C1 (de) 1995-06-30 1996-10-31 Asta Medica Ag Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen
US5988163A (en) 1995-08-02 1999-11-23 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of delivery of medicament
US5823183A (en) 1995-08-02 1998-10-20 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5692496A (en) 1995-08-02 1997-12-02 Innovative Devices, Llc Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5603315A (en) * 1995-08-14 1997-02-18 Reliable Engineering Multiple mode oxygen delivery system
SE9503344D0 (sv) * 1995-09-27 1995-09-27 Astra Ab Inhalation device
US6065472A (en) 1996-01-03 2000-05-23 Glaxo Wellcome Inc. Multidose powder inhalation device
US5699789A (en) 1996-03-11 1997-12-23 Hendricks; Mark R. Dry powder inhaler
DE19613185A1 (de) 1996-04-02 1997-10-09 Pfeiffer Erich Gmbh & Co Kg Dosiereinrichtung für strömungsfähige Medien wie Pulver/Luft-Dispersionen
US5875776A (en) 1996-04-09 1999-03-02 Vivorx Pharmaceuticals, Inc. Dry powder inhaler
US5839430A (en) * 1996-04-26 1998-11-24 Cama; Joseph Combination inhaler and peak flow rate meter
US5826633A (en) 1996-04-26 1998-10-27 Inhale Therapeutic Systems Powder filling systems, apparatus and methods
GB2312848B (en) 1996-04-26 1999-11-17 Bespak Plc Controlled flow inhalers
NZ332669A (en) 1996-04-29 1999-02-25 Dura Pharma Inc A dry power inhalation system which is flow rate independent
AUPN973596A0 (en) * 1996-05-08 1996-05-30 Resmed Limited Control of delivery pressure in cpap treatment or assisted respiration
US5813401A (en) 1996-10-15 1998-09-29 Radcliff; Janet H. Nebulizer automatic control valve
SE9700422D0 (sv) 1997-02-07 1997-02-07 Astra Ab Single dose inhaler II
US6006747A (en) 1997-03-20 1999-12-28 Dura Pharmaceuticals, Inc. Dry powder inhaler
US6131571A (en) * 1997-04-30 2000-10-17 University Of Florida Ventilation apparatus and anesthesia delivery system
DE69829969T2 (de) * 1997-07-25 2006-03-09 Minnesota Innovative Technologies & Instruments Corp. (Miti), Lino Lakes Steuervorrichtung zum zuführen von zusätzlichem atmungssauerstoff
CA2212430A1 (en) 1997-08-07 1999-02-07 George Volgyesi Inhalation device
US5855202A (en) 1997-10-08 1999-01-05 Andrade; Joseph R. Aerosol holding chamber for a metered-dose inhaler
US6067984A (en) * 1997-10-14 2000-05-30 Piper; Samuel David Pulmonary modulator apparatus
US6032667A (en) * 1997-10-30 2000-03-07 Instrumentarium Corporation Variable orifice pulse valve
US6116238A (en) 1997-12-02 2000-09-12 Dura Pharmaceuticals, Inc. Dry powder inhaler
US6076523A (en) * 1998-01-15 2000-06-20 Nellcor Puritan Bennett Oxygen blending in a piston ventilator
US6142146A (en) 1998-06-12 2000-11-07 Microdose Technologies, Inc. Inhalation device

Also Published As

Publication number Publication date
GEP20043260B (en) 2004-06-25
TNSN99038A1 (fr) 2005-11-10
EA003196B1 (ru) 2003-02-27
AU750539B2 (en) 2002-07-18
MY131803A (en) 2007-09-28
BG65091B1 (bg) 2007-02-28
HRP990081A2 (en) 2000-02-29
OA11529A (en) 2004-05-07
AU2980399A (en) 1999-10-11
US20050090798A1 (en) 2005-04-28
US6655379B2 (en) 2003-12-02
BR9908771A (pt) 2000-12-12
WO1999047196A1 (en) 1999-09-23
AR018161A1 (es) 2001-10-31
HUP0100848A1 (hu) 2001-06-28
LT2000095A (en) 2001-05-25
MA26033A1 (fr) 2004-04-01
NZ506289A (en) 2004-12-24
LV12586A (en) 2000-12-20
PE20000346A1 (es) 2000-04-12
EA200000823A1 (ru) 2001-02-26
CA2322045A1 (en) 1999-09-23
JP2002506697A (ja) 2002-03-05
CN1292714A (zh) 2001-04-25
HRP20000608A2 (en) 2001-04-30
PA8468901A1 (es) 2000-09-29
ID26237A (id) 2000-12-07
BG104720A (en) 2001-04-30
JP4195191B2 (ja) 2008-12-10
DZ2744A1 (fr) 2004-12-28
AP2000001902A0 (en) 2000-09-30
SK13632000A3 (sk) 2001-03-12
HN1999000028A (es) 2001-06-19
AP1342A (en) 2004-12-15
TWI228998B (en) 2005-03-11
YU56600A (sh) 2004-03-12
LT4818B (lt) 2001-07-25
PL343276A1 (en) 2001-08-13
SA99200198B1 (ar) 2006-11-04
NO20004627L (no) 2000-10-11
US20030183228A1 (en) 2003-10-02
NO20004627D0 (no) 2000-09-15
KR20010041924A (ko) 2001-05-25
IS5595A (is) 2000-08-22
KR100620338B1 (ko) 2006-09-13
EE200000546A (et) 2002-02-15
EP1066074A1 (en) 2001-01-10
LV12586B (en) 2001-04-20
UY25432A1 (es) 1999-05-14
CO5060522A1 (es) 2001-07-30
CN1292714B (zh) 2012-08-01
IL138153A0 (en) 2001-10-31
SI20413A (sl) 2001-06-30
HUP0100848A3 (en) 2005-04-28
CA2322045C (en) 2007-07-10
RO121834B1 (ro) 2008-06-30

Similar Documents

Publication Publication Date Title
TR200002692T2 (tr) Aerosol haline getirilen aktif maddenin verilmesi.
TR200101033T2 (tr) Akış direnci hafifletilmiş, aerosol halindeki aktif maddenin verilmesi
BG102689A (bg) Фармацевтичен аерозолен състав за използване при лечение на респираторни смущения
BR0012013A (pt) Métodos de aerossolizar uma formulação farmacêutica, e de administrar uma formulação farmacêutica, dispositivo de aerossolização, sistema de aerossolização, e, receptáculo
CA2628857A1 (en) Formulation and method for treating neoplasms by inhalation
ATE203902T1 (de) Fluorchlorkohlenwasserstofffreie aerosolformulierungen
IS4179A (is) Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband
ATE77947T1 (de) Pentamidin enthaltende pharmazeutische zusammensetzungen.
DE69205177D1 (de) Pharmazeutische Aerosolformulierung.
ATE308317T1 (de) Zubereitungen mit einem anticholinergischen wirkstoff für die behandlung der chronischen obstruktiven lungenerkrankung
IS4178A (is) Lyfjablanda til innöndunar sem inniheldur insúlín
CA2195065A1 (en) Inhalation composition
WO2005044226A3 (en) Lipid formulations for spontaneous drug encapsulation
DE60135099D1 (de) Pulverinhalator
TW200602054A (en) Use of compounds in a dry powder inhaler
ATE271852T1 (de) Verbesserte inhalationspräparate
EP1110547A3 (en) Helium and neon as means delivering drug in inhaler
DE60119687D1 (de) Verabreichungsverfahren von S-Adenosylmethionin in Form eines mikrofeinen Pulvers durch Inhalieren
DE60202299D1 (de) Pharmazeutische zusammensetzung enthaltend salmeterol und budesonid zur behandlung von atemkrankheiten
TH59260A3 (th) การให้สารออกฤทธิ์ที่ได้รับการทำเป็นแอโรซอล
ECSP992889A (es) Administracion de un agente activo en aerosol
TH16088A (th) สูตรผสมสำหรับการสูดดม