PE20000346A1 - Administracion de un agente activo en aerosol - Google Patents
Administracion de un agente activo en aerosolInfo
- Publication number
- PE20000346A1 PE20000346A1 PE1999000202A PE00020299A PE20000346A1 PE 20000346 A1 PE20000346 A1 PE 20000346A1 PE 1999000202 A PE1999000202 A PE 1999000202A PE 00020299 A PE00020299 A PE 00020299A PE 20000346 A1 PE20000346 A1 PE 20000346A1
- Authority
- PE
- Peru
- Prior art keywords
- hormone
- bormeron
- active agent
- refers
- interferon
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title abstract 3
- 239000000443 aerosol Substances 0.000 title abstract 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
- 102100022712 Alpha-1-antitrypsin Human genes 0.000 abstract 1
- VOVIALXJUBGFJZ-KWVAZRHASA-N Budesonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@H]3OC(CCC)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O VOVIALXJUBGFJZ-KWVAZRHASA-N 0.000 abstract 1
- 102000055006 Calcitonin Human genes 0.000 abstract 1
- 108060001064 Calcitonin Proteins 0.000 abstract 1
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 1
- 229930105110 Cyclosporin A Natural products 0.000 abstract 1
- 108010036949 Cyclosporine Proteins 0.000 abstract 1
- 102000038461 Growth Hormone-Releasing Hormone Human genes 0.000 abstract 1
- 239000000095 Growth Hormone-Releasing Hormone Substances 0.000 abstract 1
- 102000002265 Human Growth Hormone Human genes 0.000 abstract 1
- 108010000521 Human Growth Hormone Proteins 0.000 abstract 1
- 239000000854 Human Growth Hormone Substances 0.000 abstract 1
- 102000004877 Insulin Human genes 0.000 abstract 1
- 108090001061 Insulin Proteins 0.000 abstract 1
- 102000006992 Interferon-alpha Human genes 0.000 abstract 1
- 108010047761 Interferon-alpha Proteins 0.000 abstract 1
- 102000014150 Interferons Human genes 0.000 abstract 1
- 108010050904 Interferons Proteins 0.000 abstract 1
- 102000009151 Luteinizing Hormone Human genes 0.000 abstract 1
- 108010073521 Luteinizing Hormone Proteins 0.000 abstract 1
- 102000003982 Parathyroid hormone Human genes 0.000 abstract 1
- 108090000445 Parathyroid hormone Proteins 0.000 abstract 1
- 101710142969 Somatoliberin Proteins 0.000 abstract 1
- 102000005157 Somatostatin Human genes 0.000 abstract 1
- 108010056088 Somatostatin Proteins 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 108010050122 alpha 1-Antitrypsin Proteins 0.000 abstract 1
- 229940024142 alpha 1-antitrypsin Drugs 0.000 abstract 1
- 229960004436 budesonide Drugs 0.000 abstract 1
- 229960004015 calcitonin Drugs 0.000 abstract 1
- BBBFJLBPOGFECG-VJVYQDLKSA-N calcitonin Chemical compound N([C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(N)=O)C(C)C)C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 BBBFJLBPOGFECG-VJVYQDLKSA-N 0.000 abstract 1
- 229960001265 ciclosporin Drugs 0.000 abstract 1
- 229930182912 cyclosporin Natural products 0.000 abstract 1
- 229960004222 factor ix Drugs 0.000 abstract 1
- 229960000301 factor viii Drugs 0.000 abstract 1
- 230000003325 follicular Effects 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 230000003434 inspiratory effect Effects 0.000 abstract 1
- 229940125396 insulin Drugs 0.000 abstract 1
- 229940079322 interferon Drugs 0.000 abstract 1
- 239000003055 low molecular weight heparin Substances 0.000 abstract 1
- 229940127215 low-molecular weight heparin Drugs 0.000 abstract 1
- 229940040129 luteinizing hormone Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000199 parathyroid hormone Substances 0.000 abstract 1
- 229960001319 parathyroid hormone Drugs 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
- NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 abstract 1
- 229960000553 somatostatin Drugs 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Otolaryngology (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Steroid Compounds (AREA)
Abstract
SE REFIERE A UNA COMPOSICION EN AEROSOL CON UN INDICE DE FLUJO INSPIRATORIO INFERIOR A 17 LITROS POR MINUTO QUE COMPRENDE UN AGENTE ACTIVO EN FORMA DE POLVO SECO, NEBULIZACION, SOLUCION, SUSPENSION, QUE OPCIONALMENTE ESTA MEZCLADO CON UN IMPELENTE. EL AGENTE ACTIVO PUEDE SER CICLOSPORINA, HORMONA PARATIROIDEA, HORMONA FOLICULO ESTIMULANTE, ANTITRIPSINA ALFA-1, BUDESONIDA, HORMONA DEL CRECIMIENTO HUMANO, HORMONA LIBERADORA DE LA HORMONA DEL CRECIMIENTO, INTERFERON ALFA, INTERFERON BETA, FACTOR ESTIMULANTE DE COLONIAS DEL CRECIMIENTO, HORMONA LIBERADORA DE LA HORMONA LUTEINIZANTE, CALCITONINA, HEPARINA DE BAJO PESO MOLECULAR, SOMATOSTATINA, ANTICUERPO DEL VIRUS SINCITIAL RESPIRATORIO, ERITROPOYETINA, FACTOR VIII, FACTOR IX, CEREDASA, CEREZIMA, INSULINA. TAMBIEN SE REFIERE A UN DISPOSITIVO QUE PRESENTA UN REGULADOR DE FLUJO CON ABERTURAS DE 0,5 mm A 0,9 mm DE DIAMETRO EN EL CUAL EL REGULADOR DE FLUJO CONSISTE EN UNA VALVULA
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7821498P | 1998-03-16 | 1998-03-16 | |
| US7821298P | 1998-03-16 | 1998-03-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20000346A1 true PE20000346A1 (es) | 2000-04-12 |
Family
ID=26760240
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1999000202A PE20000346A1 (es) | 1998-03-16 | 1999-03-15 | Administracion de un agente activo en aerosol |
Country Status (42)
| Country | Link |
|---|---|
| US (2) | US6655379B2 (es) |
| EP (1) | EP1066074A1 (es) |
| JP (1) | JP4195191B2 (es) |
| KR (1) | KR100620338B1 (es) |
| CN (1) | CN1292714B (es) |
| AP (1) | AP1342A (es) |
| AR (1) | AR018161A1 (es) |
| AU (1) | AU750539B2 (es) |
| BG (1) | BG65091B1 (es) |
| BR (1) | BR9908771A (es) |
| CA (1) | CA2322045C (es) |
| CO (1) | CO5060522A1 (es) |
| DZ (1) | DZ2744A1 (es) |
| EA (1) | EA003196B1 (es) |
| EE (1) | EE200000546A (es) |
| GE (1) | GEP20043260B (es) |
| HN (1) | HN1999000028A (es) |
| HR (2) | HRP20000608A2 (es) |
| HU (1) | HUP0100848A3 (es) |
| ID (1) | ID26237A (es) |
| IL (1) | IL138153A0 (es) |
| IS (1) | IS5595A (es) |
| LT (1) | LT4818B (es) |
| LV (1) | LV12586B (es) |
| MA (1) | MA26033A1 (es) |
| MY (1) | MY131803A (es) |
| NO (1) | NO20004627L (es) |
| NZ (1) | NZ506289A (es) |
| OA (1) | OA11529A (es) |
| PA (1) | PA8468901A1 (es) |
| PE (1) | PE20000346A1 (es) |
| PL (1) | PL343276A1 (es) |
| RO (1) | RO121834B1 (es) |
| SA (1) | SA99200198B1 (es) |
| SI (1) | SI20413A (es) |
| SK (1) | SK13632000A3 (es) |
| TN (1) | TNSN99038A1 (es) |
| TR (1) | TR200002692T2 (es) |
| TW (1) | TWI228998B (es) |
| UY (1) | UY25432A1 (es) |
| WO (1) | WO1999047196A1 (es) |
| YU (1) | YU56600A (es) |
Families Citing this family (135)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2179831T3 (es) | 1992-09-29 | 2003-02-01 | Inhale Therapeutic Syst | Liberacion en los pulmones de fragmentos activos de hormona paratiroidiana. |
| CA2183577C (en) | 1994-03-07 | 2007-10-30 | John S. Patton | Methods and compositions for pulmonary delivery of insulin |
| US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| US6309671B1 (en) * | 1995-04-14 | 2001-10-30 | Inhale Therapeutic Systems | Stable glassy state powder formulations |
| US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
| US6309623B1 (en) | 1997-09-29 | 2001-10-30 | Inhale Therapeutic Systems, Inc. | Stabilized preparations for use in metered dose inhalers |
| US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
| GB9807232D0 (en) * | 1998-04-03 | 1998-06-03 | Univ Cardiff | Aerosol composition |
| UA73924C2 (en) * | 1998-10-09 | 2005-10-17 | Nektar Therapeutics | Device for delivering active agent formulation to lungs of human patient |
| GB2353222B (en) * | 1999-06-23 | 2001-09-19 | Cambridge Consultants | Inhalers |
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| US6606992B1 (en) | 1999-06-30 | 2003-08-19 | Nektar Therapeutics | Systems and methods for aerosolizing pharmaceutical formulations |
| US7305986B1 (en) | 1999-07-23 | 2007-12-11 | Mannkind Corporation | Unit dose capsules for use in a dry powder inhaler |
| US7464706B2 (en) * | 1999-07-23 | 2008-12-16 | Mannkind Corporation | Unit dose cartridge and dry powder inhaler |
| JP4711520B2 (ja) * | 2000-03-21 | 2011-06-29 | 日本ケミカルリサーチ株式会社 | 生理活性ペプチド含有粉末 |
| PE20011227A1 (es) * | 2000-04-17 | 2002-01-07 | Chiesi Farma Spa | Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros |
| US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
| US8404217B2 (en) | 2000-05-10 | 2013-03-26 | Novartis Ag | Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use |
| AU6124601A (en) | 2000-05-10 | 2001-11-20 | Alliance Pharmaceutical Corporation | Phospholipid-based powders for drug delivery |
| DK1913939T3 (en) | 2000-06-27 | 2017-09-18 | Vectura Ltd | Formulations for use in inhalers |
| US6339107B1 (en) | 2000-08-02 | 2002-01-15 | Syntex (U.S.A.) Llc | Methods for treatment of Emphysema using 13-cis retinoic acid |
| EP1935869A1 (en) | 2000-10-02 | 2008-06-25 | F. Hoffmann-La Roche Ag | Retinoids for the treatment of emphysema |
| US7049283B2 (en) | 2000-12-06 | 2006-05-23 | Novartis Ag | Pharmaceutical compositions for the oral delivery of pharmacologically active agents |
| US6782887B2 (en) * | 2001-01-12 | 2004-08-31 | Becton, Dickinson And Company | Medicament respiratory delivery device and cartridge |
| ES2431634T3 (es) | 2001-06-20 | 2013-11-27 | Novartis Ag | Dispositivo de administración de aerosol |
| GB2380946A (en) * | 2001-08-31 | 2003-04-23 | Medic Aid Ltd | Nebuliser arrangement |
| EP1458360B1 (en) | 2001-12-19 | 2011-05-11 | Novartis AG | Pulmonary delivery of aminoglycosides |
| CA2479751C (en) | 2002-03-20 | 2008-06-03 | Trent Poole | Inhalation apparatus |
| SI2143458T1 (sl) | 2002-03-22 | 2017-09-29 | Clinical Designs Limited | Vpenjalo vsebnika |
| UA80123C2 (en) * | 2002-04-09 | 2007-08-27 | Boehringer Ingelheim Pharma | Inhalation kit comprising inhalable powder of tiotropium |
| US7185651B2 (en) | 2002-06-18 | 2007-03-06 | Nektar Therapeutics | Flow regulator for aerosol drug delivery and methods |
| WO2004054606A1 (en) * | 2002-12-13 | 2004-07-01 | Pfizer Products Inc. | Method of decreasing hepatic glucose output in diabetic patients |
| US20050236296A1 (en) * | 2002-12-30 | 2005-10-27 | Nektar Therapeutics (Formerly Inhale Therapeutic Systems, Inc.) | Carry case for aerosolization apparatus |
| GB0304000D0 (en) | 2003-02-21 | 2003-03-26 | Clinical Designs Ltd | Dispenser |
| EP1610850B2 (en) * | 2003-04-09 | 2020-08-05 | Novartis AG | Aerosolization apparatus with air inlet shield |
| PT3103800T (pt) | 2003-04-11 | 2018-07-27 | Ptc Therapeutics Inc | Compostos do ácido 1,2,4-oxadiazole benzóico e a sua utilização para a supressão sem sentido e o tratamento de doenças |
| GB0313604D0 (en) * | 2003-06-12 | 2003-07-16 | Britannia Pharmaceuticals Ltd | Delivery device for powdered medicament |
| BR0318454A (pt) | 2003-08-08 | 2006-09-12 | Abgenix Inc | anticorpos dirigidos a hormÈnio da paratireóide (pth) e seus usos |
| US7318925B2 (en) * | 2003-08-08 | 2008-01-15 | Amgen Fremont, Inc. | Methods of use for antibodies against parathyroid hormone |
| NZ547689A (en) | 2003-11-19 | 2009-05-31 | Signal Pharm Llc | Indazole compounds and methods of use thereof as protein kinase inhibitors |
| GB0327112D0 (en) | 2003-11-21 | 2003-12-24 | Clincial Designs Ltd | Dispenser and reservoir |
| GB0328859D0 (en) | 2003-12-12 | 2004-01-14 | Clinical Designs Ltd | Dispenser and counter |
| WO2005065756A2 (en) | 2003-12-30 | 2005-07-21 | Oriel Therapeutics, Inc. | Dry powder nebulizers and associated methods of dispensing dry powders |
| CA2575692C (en) | 2004-08-20 | 2014-10-14 | Mannkind Corporation | Catalysis of diketopiperazine synthesis |
| DK1791542T3 (en) | 2004-08-23 | 2015-06-15 | Mannkind Corp | Diketopiperazinsalte for pharmaceutical delivery |
| EP1791555B1 (en) * | 2004-09-10 | 2013-03-13 | Pharmaorigin ApS | Methods for treating local tracheal, bronchial or alveolar bleeding or hemoptysis |
| GB0425518D0 (en) | 2004-11-19 | 2004-12-22 | Clinical Designs Ltd | Substance source |
| US7827983B2 (en) * | 2004-12-20 | 2010-11-09 | Hewlett-Packard Development Company, L.P. | Method for making a pharmaceutically active ingredient abuse-prevention device |
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| US20160345631A1 (en) | 2005-07-19 | 2016-12-01 | James Monsees | Portable devices for generating an inhalable vapor |
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| US7973005B2 (en) * | 2006-02-09 | 2011-07-05 | Kamada Ltd. | Alpha-1 antitrypsin for treating exacerbation episodes of pulmonary diseases |
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| ATE476418T1 (de) | 2006-06-08 | 2010-08-15 | Amgen Inc | Benzamidderivate und assoziierte verwendungen |
| EP2051977A2 (en) | 2006-07-20 | 2009-04-29 | Amgen Inc. | SUBSTITUTED AZOLE AROMATIC HETEROCYCLES AS INHIBITORS OF LLbeta-HSD-1 |
| WO2008088540A2 (en) | 2006-12-26 | 2008-07-24 | Amgen Inc. | N-cyclohexyl benzamides and benzeneacetamides as inhibitors of 11-beta-hydroxysteroid dehydrogenases |
| US8991402B2 (en) | 2007-12-18 | 2015-03-31 | Pax Labs, Inc. | Aerosol devices and methods for inhaling a substance and uses thereof |
| ES2929343T3 (es) | 2008-06-13 | 2022-11-28 | Mannkind Corp | Inhalador de polvo seco accionado por aspiración para la administración de fármacos |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| ES2904623T3 (es) | 2008-06-20 | 2022-04-05 | Mannkind Corp | Aparato interactivo para establecer un perfil en tiempo real de esfuerzos de inhalación |
| TWI494123B (zh) | 2008-08-11 | 2015-08-01 | Mannkind Corp | 超快起作用胰島素之用途 |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| GB0904040D0 (en) | 2009-03-10 | 2009-04-22 | Euro Celtique Sa | Counter |
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| US6142146A (en) | 1998-06-12 | 2000-11-07 | Microdose Technologies, Inc. | Inhalation device |
-
1999
- 1999-03-11 NZ NZ50628999A patent/NZ506289A/xx unknown
- 1999-03-11 AP APAP/P/2000/001902A patent/AP1342A/en active
- 1999-03-11 TR TR2000/02692T patent/TR200002692T2/xx unknown
- 1999-03-11 HR HR20000608A patent/HRP20000608A2/hr not_active Application Discontinuation
- 1999-03-11 GE GEAP19995591A patent/GEP20043260B/en unknown
- 1999-03-11 EE EEP200000546A patent/EE200000546A/xx unknown
- 1999-03-11 AU AU29803/99A patent/AU750539B2/en not_active Ceased
- 1999-03-11 RO ROA200000909A patent/RO121834B1/ro unknown
- 1999-03-11 IL IL13815399A patent/IL138153A0/xx not_active IP Right Cessation
- 1999-03-11 HU HU0100848A patent/HUP0100848A3/hu unknown
- 1999-03-11 LT LT2000095A patent/LT4818B/lt not_active IP Right Cessation
- 1999-03-11 OA OA1200000236A patent/OA11529A/en unknown
- 1999-03-11 BR BR9908771-5A patent/BR9908771A/pt not_active Application Discontinuation
- 1999-03-11 EP EP99911071A patent/EP1066074A1/en not_active Withdrawn
- 1999-03-11 PL PL99343276A patent/PL343276A1/xx not_active Application Discontinuation
- 1999-03-11 SI SI9920017A patent/SI20413A/sl not_active IP Right Cessation
- 1999-03-11 YU YU56600A patent/YU56600A/sh unknown
- 1999-03-11 EA EA200000823A patent/EA003196B1/ru not_active IP Right Cessation
- 1999-03-11 US US09/266,720 patent/US6655379B2/en not_active Expired - Lifetime
- 1999-03-11 ID IDW20001760A patent/ID26237A/id unknown
- 1999-03-11 WO PCT/US1999/004654 patent/WO1999047196A1/en not_active Ceased
- 1999-03-11 CA CA002322045A patent/CA2322045C/en not_active Expired - Fee Related
- 1999-03-11 KR KR1020007010232A patent/KR100620338B1/ko not_active Expired - Fee Related
- 1999-03-11 CN CN998037133A patent/CN1292714B/zh not_active Expired - Fee Related
- 1999-03-11 SK SK1363-2000A patent/SK13632000A3/sk unknown
- 1999-03-11 JP JP2000536435A patent/JP4195191B2/ja not_active Expired - Fee Related
- 1999-03-15 AR ARP990101116A patent/AR018161A1/es unknown
- 1999-03-15 PE PE1999000202A patent/PE20000346A1/es not_active Application Discontinuation
- 1999-03-15 MA MA25495A patent/MA26033A1/fr unknown
- 1999-03-15 DZ DZ990045A patent/DZ2744A1/xx active
- 1999-03-15 UY UY25432A patent/UY25432A1/es not_active Application Discontinuation
- 1999-03-15 TW TW088103965A patent/TWI228998B/zh not_active IP Right Cessation
- 1999-03-15 TN TNTNSN99038A patent/TNSN99038A1/fr unknown
- 1999-03-15 MY MYPI99000957A patent/MY131803A/en unknown
- 1999-03-16 HR HR60/078,214A patent/HRP990081A2/hr not_active Application Discontinuation
- 1999-03-16 HN HN1999000028A patent/HN1999000028A/es unknown
- 1999-03-16 CO CO99016181A patent/CO5060522A1/es unknown
- 1999-03-16 PA PA19998468901A patent/PA8468901A1/es unknown
- 1999-05-31 SA SA99200198A patent/SA99200198B1/ar unknown
-
2000
- 2000-08-22 IS IS5595A patent/IS5595A/is unknown
- 2000-08-28 BG BG104720A patent/BG65091B1/bg unknown
- 2000-09-15 NO NO20004627A patent/NO20004627L/no not_active Application Discontinuation
- 2000-09-22 LV LVP-00-129A patent/LV12586B/en unknown
-
2003
- 2003-07-25 US US10/627,591 patent/US20050090798A1/en not_active Abandoned
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