TR200002567T2 - Glisin naklini önleyiciler. - Google Patents
Glisin naklini önleyiciler.Info
- Publication number
- TR200002567T2 TR200002567T2 TR2000/02567T TR200002567T TR200002567T2 TR 200002567 T2 TR200002567 T2 TR 200002567T2 TR 2000/02567 T TR2000/02567 T TR 2000/02567T TR 200002567 T TR200002567 T TR 200002567T TR 200002567 T2 TR200002567 T2 TR 200002567T2
- Authority
- TR
- Turkey
- Prior art keywords
- transport inhibitors
- relates
- glycine transport
- glycine
- diseases
- Prior art date
Links
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 title abstract 4
- 239000004471 Glycine Substances 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 206010019196 Head injury Diseases 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 abstract 1
- 208000028017 Psychotic disease Diseases 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 201000006417 multiple sclerosis Diseases 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 208000027232 peripheral nervous system disease Diseases 0.000 abstract 1
- 125000004193 piperazinyl group Chemical group 0.000 abstract 1
- 125000003386 piperidinyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98200701 | 1998-03-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200002567T2 true TR200002567T2 (tr) | 2000-11-21 |
Family
ID=8233444
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2000/02567T TR200002567T2 (tr) | 1998-03-06 | 1999-02-26 | Glisin naklini önleyiciler. |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP1059922A2 (fr) |
| JP (1) | JP2002505277A (fr) |
| KR (1) | KR20010032968A (fr) |
| CN (1) | CN1292698A (fr) |
| AU (1) | AU3408999A (fr) |
| BG (1) | BG104685A (fr) |
| BR (1) | BR9907951A (fr) |
| CA (1) | CA2322164A1 (fr) |
| EE (1) | EE200000482A (fr) |
| HR (1) | HRP20000523A2 (fr) |
| HU (1) | HUP0101048A2 (fr) |
| IL (1) | IL138228A0 (fr) |
| NO (1) | NO20004431L (fr) |
| PL (1) | PL343435A1 (fr) |
| SK (1) | SK13082000A3 (fr) |
| TR (1) | TR200002567T2 (fr) |
| WO (1) | WO1999044596A2 (fr) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0011997A (pt) | 1999-06-28 | 2002-03-05 | Janssen Pharmaceutica Nv | Inibidores da replicação do vìrus sincicial respiratório |
| UA73749C2 (en) * | 1999-11-01 | 2005-09-15 | Diarylenines | |
| AU2001254546A1 (en) * | 2000-04-20 | 2001-11-07 | Nps Allelix Corp. | Aminopiperidines |
| DE10040016A1 (de) * | 2000-08-16 | 2002-02-28 | Boehringer Ingelheim Pharma | Neue beta-Amyloid Inhibitoren, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| WO2002019967A2 (fr) | 2000-09-08 | 2002-03-14 | Gliatech, Inc. | Derives hydraziniques substitues |
| US6946474B2 (en) | 2000-09-14 | 2005-09-20 | Merck & Co., Inc. | Nitrogen-containing compounds and their use as glycine transport inhibitors |
| AR032653A1 (es) | 2001-02-09 | 2003-11-19 | Telik Inc | Inhibidores heterociclicos del trasportador de glicina 2 composiciones farmaceuticas, uso y metodos. |
| US7030150B2 (en) | 2001-05-11 | 2006-04-18 | Trimeris, Inc. | Benzimidazole compounds and antiviral uses thereof |
| DK1703909T3 (da) * | 2003-09-09 | 2009-06-22 | Hoffmann La Roche | 1-benzoyl-piperazinderivater som glycinoptagelsesinhibitorer til behandling af psykoser |
| WO2005023260A1 (fr) * | 2003-09-09 | 2005-03-17 | F. Hoffmann-La Roche Ag | Derives de 1-(2-amino-benzol)-piperazine en tant qu'inhibiteurs de l'absorption du glycocolle pour traiter des psychoses |
| WO2005058885A2 (fr) * | 2003-12-18 | 2005-06-30 | Glaxo Group Limited | Composes |
| TW200630337A (en) | 2004-10-14 | 2006-09-01 | Euro Celtique Sa | Piperidinyl compounds and the use thereof |
| CN101072762B (zh) * | 2004-12-09 | 2010-06-23 | 弗·哈夫曼-拉罗切有限公司 | 苯基-哌嗪甲酮衍生物 |
| BRPI0519054A2 (pt) | 2004-12-15 | 2008-12-23 | Hoffmann La Roche | fenil metanonas bi e tricÍclicas substituÍdas como inibidores de transportador i de glicina (glyt-1) para o tratamento de doenÇa de alzheimer |
| PE20061156A1 (es) | 2004-12-23 | 2006-12-16 | Glaxo Group Ltd | Derivados de benzamida como agentes inhibidores del transportador de glicina |
| GB0428233D0 (en) * | 2004-12-23 | 2005-01-26 | Glaxo Group Ltd | Compounds |
| US7485637B2 (en) | 2005-01-04 | 2009-02-03 | Hoffmann-La Roche Inc. | Benzoyl-tetrahydropiperidine derivatives |
| RU2007125380A (ru) * | 2005-01-06 | 2009-02-20 | Ф. Хоффманн-Ля Рош Аг (Ch) | Сульфанил-замещенные фенилметаноны в качестве ингибиторов переносчика глицина 1 (glyt-1) для лечения неврологических и психоневрологических заболеваний |
| DE602005022113D1 (de) * | 2005-01-07 | 2010-08-12 | Hoffmann La Roche | Phenyl)methanon-derivate als glycin-transporter 1 (glyt-1) hemmer zur behandlung von neurologischen und neuropsychiatrischen erkrankungen |
| BRPI0606730A2 (pt) * | 2005-01-18 | 2009-07-14 | Hoffmann La Roche | derivados de fenil metanona 2,5-di-substituìdos como inibidores do transportador de glicina 1 (glyt-1) para o tratamento de distúbios neurológicos e neuropsiquiátricos |
| ATE447572T1 (de) | 2005-01-26 | 2009-11-15 | Hoffmann La Roche | Phenylmethanonderivate und ihre verwendung als glycin-transporter-1-hemmer |
| HRP20100076T1 (hr) * | 2005-02-07 | 2010-03-31 | F. Hoffmann - La Roche Ag | Heterociklički supstituirani fenil metanoni kao inhibitori glicin transportera 1 |
| CN100341871C (zh) * | 2005-06-03 | 2007-10-10 | 复旦大学 | 含哌啶结构的有机硫化合物，制备方法和应用 |
| WO2007110449A1 (fr) | 2006-03-29 | 2007-10-04 | Euro-Celtique S.A. | Composés de benzènesulfonamide et utilisation de ceux-ci |
| TW200812963A (en) | 2006-04-13 | 2008-03-16 | Euro Celtique Sa | Benzenesulfonamide compounds and the use thereof |
| US8791264B2 (en) | 2006-04-13 | 2014-07-29 | Purdue Pharma L.P. | Benzenesulfonamide compounds and their use as blockers of calcium channels |
| MX2009004822A (es) * | 2006-11-01 | 2009-10-19 | Purdue Pharma Lp | Compuestos de fenilpropionamida y usos de los mismos. |
| FR2910320B1 (fr) * | 2006-12-21 | 2009-02-13 | Galderma Res & Dev S N C Snc | Emulsion comprenant au moins un retinoide et du peroxyde de benzole |
| FR2910321B1 (fr) | 2006-12-21 | 2009-07-10 | Galderma Res & Dev S N C Snc | Gel creme comprenant au moins un retinoide et du peroxyde de benzole |
| WO2008124118A1 (fr) | 2007-04-09 | 2008-10-16 | Purdue Pharma L.P. | Composés benzènesulfonylés et leur utilisation |
| US8765736B2 (en) | 2007-09-28 | 2014-07-01 | Purdue Pharma L.P. | Benzenesulfonamide compounds and the use thereof |
| JP2011506441A (ja) * | 2007-12-12 | 2011-03-03 | アムジエン・インコーポレーテツド | グリシン輸送体−１阻害薬 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4219559A (en) * | 1979-01-10 | 1980-08-26 | Janssen Pharmaceutica N.V. | N-Heterocyclyl-4-piperidinamines |
| CA1140119A (fr) * | 1978-04-03 | 1983-01-25 | Joseph Torremans | Nouvelles n-heterocycle-4-piperidinamines |
| US4695575A (en) * | 1984-11-13 | 1987-09-22 | Janssen Pharmaceutica, N.V. | 4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines |
| PH23995A (en) * | 1984-01-09 | 1990-02-09 | Janssen Pharmaceutica Nv | 4((bicycle heterocyclyl)-methyl and hetero)piperidines |
| AU1041599A (en) * | 1997-11-13 | 1999-06-07 | Jose Luis Castro Pineiro | Therapeutic uses of triazolo-pyridazine derivatives |
-
1999
- 1999-02-26 WO PCT/EP1999/001309 patent/WO1999044596A2/fr not_active Ceased
- 1999-02-26 JP JP2000534198A patent/JP2002505277A/ja not_active Withdrawn
- 1999-02-26 AU AU34089/99A patent/AU3408999A/en not_active Abandoned
- 1999-02-26 CN CN998036471A patent/CN1292698A/zh active Pending
- 1999-02-26 KR KR1020007006315A patent/KR20010032968A/ko not_active Withdrawn
- 1999-02-26 TR TR2000/02567T patent/TR200002567T2/xx unknown
- 1999-02-26 HU HU0101048A patent/HUP0101048A2/hu unknown
- 1999-02-26 EP EP99915541A patent/EP1059922A2/fr not_active Withdrawn
- 1999-02-26 SK SK1308-2000A patent/SK13082000A3/sk unknown
- 1999-02-26 PL PL99343435A patent/PL343435A1/xx not_active Application Discontinuation
- 1999-02-26 EE EEP200000482A patent/EE200000482A/xx unknown
- 1999-02-26 HR HR20000523A patent/HRP20000523A2/hr not_active Application Discontinuation
- 1999-02-26 CA CA002322164A patent/CA2322164A1/fr not_active Abandoned
- 1999-02-26 BR BR9907951-8A patent/BR9907951A/pt not_active Application Discontinuation
- 1999-02-26 IL IL13822899A patent/IL138228A0/xx unknown
-
2000
- 2000-08-11 BG BG104685A patent/BG104685A/xx unknown
- 2000-09-05 NO NO20004431A patent/NO20004431L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EE200000482A (et) | 2002-02-15 |
| KR20010032968A (ko) | 2001-04-25 |
| JP2002505277A (ja) | 2002-02-19 |
| WO1999044596A3 (fr) | 2000-02-17 |
| BG104685A (en) | 2001-04-30 |
| PL343435A1 (en) | 2001-08-13 |
| BR9907951A (pt) | 2001-01-30 |
| HRP20000523A2 (en) | 2001-02-28 |
| WO1999044596A2 (fr) | 1999-09-10 |
| CA2322164A1 (fr) | 1999-09-10 |
| NO20004431D0 (no) | 2000-09-05 |
| NO20004431L (no) | 2000-10-30 |
| EP1059922A2 (fr) | 2000-12-20 |
| SK13082000A3 (sk) | 2001-03-12 |
| AU3408999A (en) | 1999-09-20 |
| HUP0101048A2 (hu) | 2001-10-28 |
| IL138228A0 (en) | 2001-10-31 |
| CN1292698A (zh) | 2001-04-25 |
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