[go: up one dir, main page]

TNSN98087A1 - Composition pharmaceutique en aerosol - Google Patents

Composition pharmaceutique en aerosol

Info

Publication number
TNSN98087A1
TNSN98087A1 TNTNSN98087A TNSN98087A TNSN98087A1 TN SN98087 A1 TNSN98087 A1 TN SN98087A1 TN TNSN98087 A TNTNSN98087 A TN TNSN98087A TN SN98087 A TNSN98087 A TN SN98087A TN SN98087 A1 TNSN98087 A1 TN SN98087A1
Authority
TN
Tunisia
Prior art keywords
aerosol
inhaler
aerosol particles
pharmaceutical composition
low volatility
Prior art date
Application number
TNTNSN98087A
Other languages
English (en)
Inventor
Gaetano Brambilla
Raffaella Garzia
Brian Meakin
David Lewis
Davis Ganderton
Paolo Ventura
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10814179&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TNSN98087(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of TNSN98087A1 publication Critical patent/TNSN98087A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

UNE COMPOSITION A UTILISER DANS UN INHALATEUR EN AEROSOL, COMPRENANT UNE SUBSTANCE ACTIVE, UN PROPULSEUR CONTENANT UN HYDROFLUOROALCANE ET UN COSOLVANT. LA COMPOSITION CONTIENT, EN OUTRE, UN COMPOSANT DE FAIBLE VOLATILITE QUI EST AJOUTE POUR AUGMENTER LE DIAMETRE AERODYNAMIQUE MASSIQUE MOYEN (MMADI) DES PARTICULES D'AEROSOL LORS DE L'EXPLOITATION DE L'INHALATEUR. AVEC L'ADJONCTION D'UN COMPOSANT DE FAIBLE VOLATILITE, LE DIAMETRE AERODYNAMIQUE MASSIQUE MOYEN (MMAD) DES PARTICULES D'AEROSOL PEUT ETRE COMPARABLE A CELUI DES PARTICULES D'AEROSOL D'UN INHALATEUR AYANT LE CFC COMME PROPULSEUR.
TNTNSN98087A 1997-06-13 1998-06-12 Composition pharmaceutique en aerosol TNSN98087A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9712434A GB2326334A (en) 1997-06-13 1997-06-13 Pharmaceutical aerosol compositions

Publications (1)

Publication Number Publication Date
TNSN98087A1 true TNSN98087A1 (fr) 2005-03-15

Family

ID=10814179

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN98087A TNSN98087A1 (fr) 1997-06-13 1998-06-12 Composition pharmaceutique en aerosol

Country Status (44)

Country Link
EP (2) EP1219293A3 (fr)
JP (1) JP4380802B2 (fr)
KR (1) KR100546239B1 (fr)
CN (1) CN1138532C (fr)
AR (1) AR012977A1 (fr)
AT (1) ATE222751T1 (fr)
AU (1) AU729966B2 (fr)
BG (1) BG63906B1 (fr)
BR (1) BR9805993B1 (fr)
CA (1) CA2263445C (fr)
CO (1) CO4940408A1 (fr)
CZ (1) CZ295521B6 (fr)
DE (1) DE69807420T3 (fr)
DK (1) DK0920302T4 (fr)
DZ (1) DZ2516A1 (fr)
EA (1) EA001259B1 (fr)
EE (1) EE03664B1 (fr)
ES (1) ES2182351T5 (fr)
GB (1) GB2326334A (fr)
GE (1) GEP20012462B (fr)
HR (1) HRP980317B1 (fr)
HU (1) HU228487B1 (fr)
ID (1) ID21491A (fr)
IL (1) IL128484A (fr)
IN (1) IN189317B (fr)
IS (1) IS2435B (fr)
IT (1) IT1293803B1 (fr)
MA (1) MA26507A1 (fr)
ME (2) ME00333B (fr)
MY (1) MY119074A (fr)
NO (1) NO327775B1 (fr)
NZ (1) NZ334149A (fr)
PL (1) PL193721B1 (fr)
PT (1) PT920302E (fr)
RS (1) RS51274B (fr)
SA (1) SA98190821B1 (fr)
SI (1) SI0920302T2 (fr)
SK (1) SK284430B6 (fr)
TN (1) TNSN98087A1 (fr)
TR (1) TR199900288T1 (fr)
TW (1) TW555570B (fr)
UA (1) UA70289C2 (fr)
WO (1) WO1998056349A1 (fr)
ZA (1) ZA985136B (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9616237D0 (en) 1996-08-01 1996-09-11 Norton Healthcare Ltd Aerosol formulations
US20010031244A1 (en) 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
DZ2947A1 (fr) * 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
IT1303788B1 (it) * 1998-11-25 2001-02-23 Chiesi Farma Spa Formulazioni di aerosol medicinali.
IT1313553B1 (it) 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
WO2001019342A2 (fr) 1999-09-11 2001-03-22 Glaxo Group Limited Preparation pharmaceutique renfermant du propionate de fluticasone
ES2234694T3 (es) * 1999-11-23 2005-07-01 Glaxo Group Limited Formulaciones farmaceuticas de salmeterol.
JP2003518484A (ja) * 1999-12-24 2003-06-10 グラクソ グループ リミテッド サルメテロールおよびプロピオン酸フルチカゾンの医薬用エアゾル製剤
IT1317846B1 (it) * 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
IT1318514B1 (it) * 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
BR0015884A (pt) 2000-05-22 2003-07-08 Chiesi Farma Spa Formulações de soluções farmacêuticas estáveis para inaladores de dose medida pressurizados
WO2002072067A2 (fr) * 2001-03-12 2002-09-19 Glaxo Group Limited Formulation aerosol pharmaceutique
ATE267591T1 (de) 2001-07-02 2004-06-15 Chiesi Farma Spa Optimierte tobramycin-formulierung zur aerosolbildung
KR100947409B1 (ko) 2002-03-01 2010-03-12 키에시 파르마슈티시 엣스. 피. 에이. 포모테롤 초미세 조성물
EP1340492A1 (fr) * 2002-03-01 2003-09-03 CHIESI FARMACEUTICI S.p.A. Formulations d'aérosol pour l'administration par voie pulmonaire de medicaments avec effet systémique
EP1340503A1 (fr) * 2002-03-01 2003-09-03 CHIESI FARMACEUTICI S.p.A. Formule d'une solution pour aerosol contenant des dérivés d'esters de 3,17 estratrien pour administration pulmonale
DE10214263A1 (de) * 2002-03-28 2003-10-16 Boehringer Ingelheim Pharma HFA-Suspensionsformulierungen enthaltend ein Anticholinergikum
DE60216242T2 (de) * 2002-06-06 2007-05-24 Chiesi Farmaceutici S.P.A. Lösung von Wirkstoffen in HFA-Treibgasen mittels Emulsionen
WO2004071488A1 (fr) * 2003-02-04 2004-08-26 Chrysalis Technologies Incorporated Preparations de perfluorocarbure et d'hydrofluorocarbure et procedes de fabrication et d'utilisation de celles-ci
MXPA05009920A (es) * 2003-03-20 2005-11-04 Boehringer Ingelheim Pharma Formulacion para un inhalador con dosis medida que emplea hidrofluoroalcanos como propulsores.
EP1915985A1 (fr) * 2003-03-20 2008-04-30 Boehringer Ingelheim Pharmaceuticals Inc. Formulation pour une dose mesurée utilisant des hydro-fluoro-alcanes en tant que propulseurs
SE0303179D0 (sv) * 2003-11-26 2003-11-26 Astrazeneca Ab Novel compounds
EP1595531A1 (fr) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Formulation d'une solution pharmaceutique stable pour aérosols doseurs sous pression
EP1809243B2 (fr) 2004-07-02 2022-06-08 Boehringer Ingelheim International GmbH Formulations de suspensions aerosol contenant tg 227 ea en tant qu'agent propulseur
DE102006017320A1 (de) 2006-04-11 2007-10-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel
GB0621707D0 (en) * 2006-10-31 2006-12-13 Univ London Pharmacy Formulations for delivery via pressurised metered dose inhalers
GB0712454D0 (en) 2007-06-27 2007-08-08 Generics Uk Ltd Pharmaceutical compositions
MX2010005036A (es) * 2007-11-07 2010-05-27 Astrazeneca Ab Formulaciones de polvo seco que comprenden derivados del acido ascorbico.
EP2613829B1 (fr) * 2010-09-06 2022-06-29 Chiesi Farmaceutici S.p.A. Aérosol-doseur
JP5409594B2 (ja) * 2010-12-22 2014-02-05 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ 加圧式定量吸入器のための安定な製薬学的溶液製剤
JP6335798B2 (ja) 2012-02-28 2018-05-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規噴射剤含有チオトロピウム製剤
RU2504402C1 (ru) * 2012-11-20 2014-01-20 Шолекс Девелопмент Гмбх Ингаляционный состав в форме аэрозоля для лечения бронхиальной астмы и хронической обструктивной болезни легких
GB201402513D0 (en) 2014-02-13 2014-04-02 Cardiff Scintigraphics Ltd Pressurised metered dose inhalers and method of manufacture
WO2016018892A1 (fr) 2014-07-29 2016-02-04 3M Innovative Properties Company Procédé de préparation d'une composition pharmaceutique
EP3436115B1 (fr) 2016-03-31 2021-07-28 Chiesi Farmaceutici S.p.A. Dispositif d'inhalation d'aérosol
ES2841649T5 (es) * 2016-09-19 2024-04-24 Mexichem Fluor Sa De Cv Composición farmacéutica
WO2025039045A1 (fr) * 2023-08-23 2025-02-27 Inhaler Supplies Pty Ltd Formulation inhalable pour actifs volatils

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE60226T1 (de) † 1986-03-10 1991-02-15 Kurt Burghart Pharmazeutikum sowie verfahren zu seiner herstellung.
PT84439B (pt) † 1986-03-10 1989-10-04 Burghart Kurt Processo de preparacao de composicoes farmaceuticas a base de nifedipina
US4899874A (en) † 1988-04-26 1990-02-13 Rehrig-Pacific Company, Inc. Stackable low depth bottle case
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
US5225183A (en) † 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
DE3905726A1 (de) * 1989-02-24 1990-08-30 Hoechst Ag Druckgaspackung und treibmittel fuer aerosole
AU658854B2 (en) † 1990-10-18 1995-05-04 Minnesota Mining And Manufacturing Company Aerosol formulation comprising beclomethasone 17,21 dipropionate
GB9024365D0 (en) * 1990-11-09 1991-01-02 Glaxo Group Ltd Medicaments
EP0504112A3 (en) * 1991-03-14 1993-04-21 Ciba-Geigy Ag Pharmaceutical aerosol formulations
SK140493A3 (en) † 1991-06-10 1994-10-05 Schering Corp Non-chlorofluorocarbon aerosol formulations
ATE226067T1 (de) * 1991-06-10 2002-11-15 Schering Corp Fluorchlorkohlenwasserstofffreie aerosolformulierungen
DE4123663A1 (de) * 1991-07-17 1993-01-21 Schwabe Willmar Gmbh & Co Aerosol-zubereitung und verwendung eines treibmittels dafuer
DE4123668A1 (de) * 1991-07-17 1993-01-21 Rovema Gmbh Verfahren und vorrichtung zur zufuehrung von folienmaterial zu einer intermittierend arbeitenden schlauchbeutelmaschine
ES2079210T3 (es) * 1991-12-12 1996-01-01 Glaxo Group Ltd Formulacion farmaceutica de aerosol.
NZ246421A (en) * 1991-12-18 1996-05-28 Minnesota Mining & Mfg Aerosol formulation containing a drug and a propellant and which is substantially free of surfactant
WO1994013263A1 (fr) * 1992-12-09 1994-06-23 Jager Paul D Formulations en aerosol de solutions medicinales stabilisees
US5502076A (en) * 1994-03-08 1996-03-26 Hoffmann-La Roche Inc. Dispersing agents for use with hydrofluoroalkane propellants
US5508023A (en) * 1994-04-11 1996-04-16 The Center For Innovative Technology Pharmaceutically acceptable agents for solubilizing, wetting, emulsifying, or lubricating in metered dose inhaler formulations which use HFC-227 propellant
US5534242A (en) † 1994-05-02 1996-07-09 Henry; Richard A. Lidocaine-vasoconstrictor aerosol preparation
EP0759744B1 (fr) † 1994-05-13 2001-10-17 Aradigm Corporation Formulation en aerosol contenant un narcotique
US5653961A (en) † 1995-03-31 1997-08-05 Minnesota Mining And Manufacturing Company Butixocort aerosol formulations in hydrofluorocarbon propellant
US5635161A (en) † 1995-06-07 1997-06-03 Abbott Laboratories Aerosol drug formulations containing vegetable oils
GB9517998D0 (en) † 1995-09-04 1995-11-08 Bioglan Lab Ltd Compositions and device for their administration
AU3453897A (en) * 1996-07-08 1998-02-02 Rhone-Poulenc Rorer Limited Medicinal cyclosporin-a aerosol solution formulation
AU726510B2 (en) † 1996-12-04 2000-11-09 Consort Medical Plc Pharmaceutical compositions and devices for their administration
EP1014943B1 (fr) † 1997-02-05 2002-06-19 Jago Research Ag Formulations medicales pour aerosols

Also Published As

Publication number Publication date
NO990594L (no) 1999-04-13
EA001259B1 (ru) 2000-12-25
ZA985136B (en) 1999-01-07
EA199900201A1 (ru) 1999-06-24
CZ46299A3 (cs) 1999-07-14
ID21491A (id) 1999-06-17
HUP0001339A3 (en) 2000-10-30
IS2435B (is) 2008-10-15
JP2000516965A (ja) 2000-12-19
ITMI971798A1 (it) 1999-01-28
ME00333B (me) 2011-02-10
CN1229355A (zh) 1999-09-22
HK1022271A1 (en) 2000-08-04
DE69807420D1 (de) 2002-10-02
GEP20012462B (en) 2001-06-25
IL128484A (en) 2004-09-27
NO990594D0 (no) 1999-02-09
PL331531A1 (en) 1999-07-19
IS4974A (is) 1999-02-11
EE9900055A (et) 1999-08-16
ES2182351T3 (es) 2003-03-01
UA70289C2 (uk) 2004-10-15
MA26507A1 (fr) 2004-12-20
SI0920302T1 (en) 2002-12-31
EP0920302A1 (fr) 1999-06-09
TW555570B (en) 2003-10-01
KR20000068171A (ko) 2000-11-25
EE03664B1 (et) 2002-04-15
SI0920302T2 (sl) 2006-10-31
WO1998056349A1 (fr) 1998-12-17
SA98190821B1 (ar) 2006-11-19
PL193721B1 (pl) 2007-03-30
EP0920302B2 (fr) 2006-06-21
HUP0001339A2 (hu) 2000-09-28
RS51274B (sr) 2010-12-31
MEP44008A (en) 2011-02-10
DK0920302T4 (da) 2006-10-09
EP1219293A3 (fr) 2003-05-28
KR100546239B1 (ko) 2006-01-26
HRP980317B1 (en) 2002-06-30
CA2263445A1 (fr) 1998-12-17
DE69807420T2 (de) 2003-05-08
SK284430B6 (sk) 2005-04-01
BR9805993A (pt) 1999-08-31
GB9712434D0 (en) 1997-08-13
NZ334149A (en) 2000-07-28
BG63906B1 (bg) 2003-06-30
BG103221A (en) 1999-09-30
CA2263445C (fr) 2008-09-09
IL128484A0 (en) 2000-01-31
MY119074A (en) 2005-03-31
IN189317B (fr) 2003-02-08
SK17699A3 (en) 1999-07-12
NO327775B1 (no) 2009-09-21
AR012977A1 (es) 2000-11-22
EP0920302B1 (fr) 2002-08-28
EP1219293A2 (fr) 2002-07-03
PT920302E (pt) 2002-11-29
IT1293803B1 (it) 1999-03-10
DE69807420T3 (de) 2006-11-16
CZ295521B6 (cs) 2005-08-17
DK0920302T3 (da) 2002-12-23
ES2182351T5 (es) 2007-03-16
JP4380802B2 (ja) 2009-12-09
ATE222751T1 (de) 2002-09-15
CN1138532C (zh) 2004-02-18
CO4940408A1 (es) 2000-07-24
AU8626298A (en) 1998-12-30
AU729966B2 (en) 2001-02-15
GB2326334A (en) 1998-12-23
HU228487B1 (en) 2013-03-28
YU6999A (sh) 2000-03-21
TR199900288T1 (xx) 1999-09-21
BR9805993B1 (pt) 2009-05-05
DZ2516A1 (fr) 2004-11-08
HRP980317A2 (en) 1999-04-30

Similar Documents

Publication Publication Date Title
TNSN98087A1 (fr) Composition pharmaceutique en aerosol
TNSN01074A1 (fr) Formulations pharmaceutiques stables en solution pour inhalateurs sous pression a comptage de dose
Kennedy Jr Dermal toxicity of ammonium perfluorooctanoate
Gowen et al. Stimulation of bone resorption in vitro by a non-prostanoid factor released by human monocytes in culture
CA2067754A1 (fr) Preparation visant l'application d'agents sous forme de mini- gouttelettes
FR2730637B1 (fr) Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
KR950010907A (ko) 생리 활성 펩티드 조성물
PT814793E (pt) Preparacoes de aerossol de prilocaina e hidrofluorocarboneto
JP2002536315A5 (fr)
ATE314092T1 (de) Biologische kleber und verfahren zur topischen verabreichung von wirkstoffen
FR2779648B1 (fr) Composition cosmetique ou pharmaceutique se presentant sous forme de solide et pouvant etre deformable
EA200101266A1 (ru) Новый препарат и форма для введения, включающие неустойчивое в кислой среде действующее вещество
WO2003032953A1 (fr) Granules contenant un agent chimique instable en milieu acide, en concentration elevee
BR0013919A (pt) Suspensão estável concentrada de pesticida
BR0007201A (pt) Composições incluindo agentes de preservação demalto-oligossacarìdeos reduzidos, e métodospara preservar um material
Samuel et al. Lead exposure in American black ducks after implementation of non-toxic shot
EP0904837A3 (fr) Catalyseur d'hydrosilylation et méthode d'hydrosilylation
TR200200841T2 (tr) Mukozaya uygulama için, siklesonid içeren farmasötik kompozisyon
WO2002011538A3 (fr) Formulation de type flottant d'agents agricoles
KR970701535A (ko) 비타민 E를 함유하는 에어로졸 약물 제형(Aerosol drug formulations containing vitamin'E)
JPS5653608A (en) Emulsified stick cosmetic
EP0374796A3 (fr) Formulations d'émulsions stables de pesticides organiques insolubles dans l'eau
JPS57185254A (en) Novel carcinostatic substances and their preparation
FR2406998A1 (fr) Batonnet deodorant contenant un bicarbonate
JPS5572110A (en) Transfusion fluid for oxygen transfer