SMT201600031B - Composti eterociclici di fenossimetile - Google Patents

Composti eterociclici di fenossimetile

Info

Publication number: SMT201600031B
Authority: SM; San Marino
Prior art keywords: phenossimethyl; heterocyclic compounds; heterocyclic; compounds
Prior art date: 2009-05-07

Application number

SM201600031T

Other languages

English (en)

Inventor

Gideon Shapiro

Amy Ripka

Richard Chesworth

Original Assignee

Forum Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-05-07

Filing date

2016-02-04

Publication date

2016-02-25

2016-02-04 Application filed by Forum Pharmaceuticals Inc filed Critical Forum Pharmaceuticals Inc

2016-02-25 Publication of SMT201600031B publication Critical patent/SMT201600031B/it

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Psychiatry (AREA)
Obesity (AREA)
Hematology (AREA)
Psychology (AREA)
Endocrinology (AREA)
Addiction (AREA)
Emergency Medicine (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Child & Adolescent Psychology (AREA)
Reproductive Health (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Hydrogenated Pyridines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

SM201600031T 2009-05-07 2016-02-04 Composti eterociclici di fenossimetile SMT201600031B (it)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US17641309P	2009-05-07	2009-05-07
EP09796217A EP2427454B1 (en)	2009-05-07	2009-12-18	Phenoxymethyl heterocyclic compounds

Publications (1)

Publication Number	Publication Date
SMT201600031B true SMT201600031B (it)	2016-02-25

Family

ID=41549054

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SM201300070T SMT201300070B (it)	2009-05-07	2013-06-20	Composti eterociclici di fenossimetile
SM201600031T SMT201600031B (it)	2009-05-07	2016-02-04	Composti eterociclici di fenossimetile

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
SM201300070T SMT201300070B (it)	2009-05-07	2013-06-20	Composti eterociclici di fenossimetile

Country Status (32)

Country	Link
US (3)	US8343973B2 (it)
EP (3)	EP3020716A1 (it)
JP (2)	JP5628902B2 (it)
KR (1)	KR101662699B1 (it)
CN (2)	CN105125547A (it)
AU (1)	AU2009345802B2 (it)
BR (1)	BRPI0924617A8 (it)
CA (1)	CA2761032A1 (it)
CL (1)	CL2011002792A1 (it)
CO (1)	CO6460744A2 (it)
CR (1)	CR20110648A (it)
DK (2)	DK2427454T3 (it)
EC (1)	ECSP11011479A (it)
ES (2)	ES2554788T3 (it)
HR (2)	HRP20130482T1 (it)
HU (1)	HUE026238T2 (it)
IL (2)	IL216149A (it)
ME (1)	ME02375B (it)
MX (1)	MX2011011755A (it)
MY (1)	MY183910A (it)
NZ (1)	NZ596753A (it)
PE (1)	PE20120900A1 (it)
PH (1)	PH12013501321A1 (it)
PL (2)	PL2427454T3 (it)
PT (2)	PT2617420E (it)
RS (2)	RS54529B1 (it)
RU (1)	RU2531274C2 (it)
SG (1)	SG175900A1 (it)
SI (2)	SI2427454T1 (it)
SM (2)	SMT201300070B (it)
WO (1)	WO2010128995A1 (it)
ZA (1)	ZA201108920B (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2009262241B2 (en)	2008-06-25	2014-05-22	Forum Pharmaceuticals Inc.	1, 2 disubstituted heterocyclic compounds
RS54529B1 (sr)	2009-05-07	2016-06-30	Forum Pharmaceuticals Inc.	Fenoksimetil heterociklična jedinjenja
MX2013009575A (es)	2011-02-18	2014-10-14	Exonhit Therapeutics Sa	Derivados de 6, 7-dialcoxi-3-isoquinolinol sustituidos como inhibidores de fosfodiesterasa 10 (pdei0a).
WO2013185284A1 (en)	2012-06-12	2013-12-19	Abbott Laboratories	Pyridinone and pyridazinone derivatives
WO2014071044A1 (en)	2012-11-01	2014-05-08	Allergan, Inc.	Substituted 6,7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (pde10a)
ES2480341B1 (es)	2013-01-24	2015-01-22	Palobiofarma S.L	Nuevos derivados de pirimidina como inhibidores de la fosfodiesterasa 10 (PDE-10)
TW201512201A (zh) *	2013-03-14	2015-04-01	Forum Pharmaceuticals Inc	化合物的多晶型及鹽類
TWI634114B (zh) *	2013-05-08	2018-09-01	永恒生物科技公司	作為激酶抑制劑之呋喃酮化合物
WO2015006689A1 (en)	2013-07-12	2015-01-15	University Of South Alabama	Treatment and diagnosis of cancer and precancerous conditions using pde10a inhibitors and methods to measure pde10a expression
US9200016B2 (en)	2013-12-05	2015-12-01	Allergan, Inc.	Substituted 6, 7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (PDE 10A)
CA3121202A1 (en)	2018-11-30	2020-06-04	Nuvation Bio Inc.	Pyrrole and pyrazole compounds and methods of use thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL149177A0 (en) *	1999-11-05	2002-11-10	Sod Conseils Rech Applic	Novel heterocyclic compounds and their use as medicines
US20030032579A1 (en) *	2001-04-20	2003-02-13	Pfizer Inc.	Therapeutic use of selective PDE10 inhibitors
AU2003244080A1 (en)	2002-06-26	2004-01-19	Kyowa Hakko Kogyo Co., Ltd.	Phosphodiesterase inhibitor
AU2005323794B2 (en) *	2005-01-07	2012-07-19	Pfizer Products Inc.	Heteroaromatic quinoline compounds and their use as PDE10 inhibitors
NL2000397C2 (nl) *	2006-01-05	2007-10-30	Pfizer Prod Inc	Bicyclische heteroarylverbindingen als PDE10 inhibitoren.
EP1845098A1 (en) *	2006-03-29	2007-10-17	Ferrer Internacional, S.A.	Imidazo[1,2-b]pyridazines, their processes of preparation and their use as GABA receptor ligands
CA2650976A1 (en) *	2006-05-02	2007-11-15	Pfizer Products Inc.	Bicyclic heteroaryl compounds as pde10 inhibitors
WO2008033455A2 (en)	2006-09-13	2008-03-20	The Institutes For Pharmaceutical Discovery, Llc	Biphenyl and heteroaryl phenyl derivatives as protein tyrosine phosphatases inhibitors
FR2928924B1 (fr) *	2008-03-21	2010-04-23	Sanofi Aventis	Derives polysubstitues de 6-heteroaryle-imidazo°1,2-a! pyridines, leur preparation et leur application en therapeutique
AU2009262241B2 (en) *	2008-06-25	2014-05-22	Forum Pharmaceuticals Inc.	1, 2 disubstituted heterocyclic compounds
RS54529B1 (sr)	2009-05-07	2016-06-30	Forum Pharmaceuticals Inc.	Fenoksimetil heterociklična jedinjenja
AU2010289353B2 (en) *	2009-09-03	2016-12-08	Allergan, Inc.	Compounds as tyrosine kinase modulators
PT3311666T (pt) *	2010-08-18	2021-06-21	Biosplice Therapeutics Inc	Dicetonas e hidroxicetonas como ativadores da via de sinalização de catenina

2009
- 2009-12-18 RS RS20150803A patent/RS54529B1/sr unknown
- 2009-12-18 BR BRPI0924617A patent/BRPI0924617A8/pt not_active IP Right Cessation
- 2009-12-18 CN CN201510438849.1A patent/CN105125547A/zh active Pending
- 2009-12-18 PT PT131503229T patent/PT2617420E/pt unknown
- 2009-12-18 DK DK09796217.9T patent/DK2427454T3/da active
- 2009-12-18 NZ NZ596753A patent/NZ596753A/xx not_active IP Right Cessation
- 2009-12-18 MY MYPI2011005358A patent/MY183910A/en unknown
- 2009-12-18 PT PT97962179T patent/PT2427454E/pt unknown
- 2009-12-18 CN CN200980159735.6A patent/CN102459242B/zh not_active Expired - Fee Related
- 2009-12-18 SG SG2011081437A patent/SG175900A1/en unknown
- 2009-12-18 EP EP15184753.0A patent/EP3020716A1/en not_active Withdrawn
- 2009-12-18 ME MEP-2015-210A patent/ME02375B/me unknown
- 2009-12-18 KR KR1020117028223A patent/KR101662699B1/ko not_active Expired - Fee Related
- 2009-12-18 AU AU2009345802A patent/AU2009345802B2/en not_active Ceased
- 2009-12-18 DK DK13150322.9T patent/DK2617420T3/da active
- 2009-12-18 SI SI200930609T patent/SI2427454T1/sl unknown
- 2009-12-18 EP EP09796217A patent/EP2427454B1/en active Active
- 2009-12-18 CA CA2761032A patent/CA2761032A1/en not_active Abandoned
- 2009-12-18 RU RU2011149637/04A patent/RU2531274C2/ru not_active IP Right Cessation
- 2009-12-18 PL PL09796217T patent/PL2427454T3/pl unknown
- 2009-12-18 WO PCT/US2009/068644 patent/WO2010128995A1/en not_active Ceased
- 2009-12-18 ES ES13150322.9T patent/ES2554788T3/es active Active
- 2009-12-18 MX MX2011011755A patent/MX2011011755A/es active IP Right Grant
- 2009-12-18 HU HUE13150322A patent/HUE026238T2/en unknown
- 2009-12-18 HR HRP20130482AT patent/HRP20130482T1/hr unknown
- 2009-12-18 JP JP2012509778A patent/JP5628902B2/ja not_active Expired - Fee Related
- 2009-12-18 SI SI200931314T patent/SI2617420T1/sl unknown
- 2009-12-18 PE PE2011001918A patent/PE20120900A1/es not_active Application Discontinuation
- 2009-12-18 RS RS20130218A patent/RS52838B/sr unknown
- 2009-12-18 US US12/642,026 patent/US8343973B2/en not_active Expired - Fee Related
- 2009-12-18 PL PL13150322T patent/PL2617420T3/pl unknown
- 2009-12-18 ES ES09796217T patent/ES2409404T3/es active Active
- 2009-12-18 EP EP13150322.9A patent/EP2617420B1/en active Active
2011
- 2011-11-03 IL IL216149A patent/IL216149A/en not_active IP Right Cessation
- 2011-11-07 CL CL2011002792A patent/CL2011002792A1/es unknown
- 2011-11-11 CO CO11153626A patent/CO6460744A2/es active IP Right Grant
- 2011-11-24 EC EC2011011479A patent/ECSP11011479A/es unknown
- 2011-12-05 ZA ZA2011/08920A patent/ZA201108920B/en unknown
- 2011-12-05 CR CR20110648A patent/CR20110648A/es unknown
2012
- 2012-12-20 US US13/722,595 patent/US8946222B2/en not_active Expired - Fee Related
2013
- 2013-06-20 SM SM201300070T patent/SMT201300070B/it unknown
- 2013-06-20 PH PH12013501321A patent/PH12013501321A1/en unknown
2014
- 2014-10-02 JP JP2014204220A patent/JP5943053B2/ja not_active Expired - Fee Related
- 2014-12-09 US US14/564,507 patent/US20150322069A1/en not_active Abandoned
2015
- 2015-11-25 HR HRP20151273TT patent/HRP20151273T1/hr unknown
2016
- 2016-02-04 SM SM201600031T patent/SMT201600031B/it unknown
- 2016-02-10 IL IL244059A patent/IL244059A0/en unknown

Also Published As

Publication number	Publication date
PL2427454T3 (pl)	2013-09-30
EP2427454B1 (en)	2013-03-20
MX2011011755A (es)	2012-03-16
PT2617420E (pt)	2015-12-18
CR20110648A (es)	2012-03-28
US20130143888A1 (en)	2013-06-06
MY183910A (en)	2021-03-17
DK2427454T3 (da)	2013-06-17
ZA201108920B (en)	2012-08-29
JP5628902B2 (ja)	2014-11-19
HRP20151273T1 (hr)	2016-01-29
IL216149A0 (en)	2012-01-31
EP2427454A1 (en)	2012-03-14
JP5943053B2 (ja)	2016-06-29
RS52838B (sr)	2013-10-31
US8343973B2 (en)	2013-01-01
DK2617420T3 (da)	2015-12-07
WO2010128995A1 (en)	2010-11-11
SI2427454T1 (sl)	2013-08-30
BRPI0924617A8 (pt)	2017-10-03
ME02375B (me)	2016-06-20
RU2011149637A (ru)	2013-06-20
NZ596753A (en)	2013-09-27
CN102459242A (zh)	2012-05-16
RS54529B1 (sr)	2016-06-30
HK1186981A1 (en)	2014-03-28
IL244059A0 (en)	2016-04-21
CN102459242B (zh)	2015-08-26
HRP20130482T1 (en)	2013-08-31
AU2009345802B2 (en)	2016-05-26
HUE026238T2 (en)	2016-06-28
US20150322069A1 (en)	2015-11-12
PH12013501321B1 (en)	2014-08-27
EP3020716A1 (en)	2016-05-18
BRPI0924617A2 (it)	2017-07-11
PE20120900A1 (es)	2012-08-14
HK1167402A1 (en)	2012-11-30
CO6460744A2 (es)	2012-06-15
ES2554788T3 (es)	2015-12-23
JP2015038112A (ja)	2015-02-26
EP2617420A1 (en)	2013-07-24
ES2409404T3 (es)	2013-06-26
CL2011002792A1 (es)	2012-06-01
US8946222B2 (en)	2015-02-03
KR20120027268A (ko)	2012-03-21
SI2617420T1 (sl)	2016-02-29
JP2012526107A (ja)	2012-10-25
US20100292238A1 (en)	2010-11-18
SMT201300070B (it)	2013-09-06
PL2617420T3 (pl)	2016-04-29
PT2427454E (pt)	2013-06-20
RU2531274C2 (ru)	2014-10-20
KR101662699B1 (ko)	2016-10-05
SG175900A1 (en)	2011-12-29
AU2009345802A1 (en)	2011-12-15
CN105125547A (zh)	2015-12-09
PH12013501321A1 (en)	2014-08-27
IL216149A (en)	2016-02-29
ECSP11011479A (es)	2011-12-30
EP2617420B1 (en)	2015-09-23
CA2761032A1 (en)	2010-11-11

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DOP2012000114A (es)	2012-08-15	Inhibidor bromodominio de benzodiazepina
BR112012005616A2 (pt)	2016-06-21	compostos antivirais heterocíclicos
EP2485589A4 (en)	2013-02-06	HETEROARYL-BTK INHIBITORS
SMT201600291B (it)	2016-11-10	Inibitori di proteasi hcv
SMT201600031B (it)	2016-02-25	Composti eterociclici di fenossimetile
BRPI1010852A2 (pt)	2019-09-24	compostos antivirais heterocíclicos
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