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SK120895A3 - Pyridine derivatives, process for preparing the same and intermediate products in this process and pharmaceutical compositions containing them - Google Patents

Pyridine derivatives, process for preparing the same and intermediate products in this process and pharmaceutical compositions containing them Download PDF

Info

Publication number
SK120895A3
SK120895A3 SK1208-95A SK120895A SK120895A3 SK 120895 A3 SK120895 A3 SK 120895A3 SK 120895 A SK120895 A SK 120895A SK 120895 A3 SK120895 A3 SK 120895A3
Authority
SK
Slovakia
Prior art keywords
group
carbon atoms
formula
alkylene
pyridyl
Prior art date
Application number
SK1208-95A
Other languages
English (en)
Slovak (sk)
Inventor
Michael G Wayne
Michael J Smithers
John W Rayner
Alan W Faull
Robert J Pearce
Andrew G Brewster
Richard E Shute
Stuart D Mills
Peter W R Caulkett
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939306453A external-priority patent/GB9306453D0/en
Priority claimed from GB939325605A external-priority patent/GB9325605D0/en
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of SK120895A3 publication Critical patent/SK120895A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Electroluminescent Light Sources (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrrole Compounds (AREA)
  • Peptides Or Proteins (AREA)
SK1208-95A 1993-03-29 1994-03-28 Pyridine derivatives, process for preparing the same and intermediate products in this process and pharmaceutical compositions containing them SK120895A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939306453A GB9306453D0 (en) 1993-03-29 1993-03-29 Heterocyclic derivatives
GB939325605A GB9325605D0 (en) 1993-12-15 1993-12-15 Heterocyclic derivatives
PCT/GB1994/000647 WO1994022834A1 (fr) 1993-03-29 1994-03-28 Derives heterocycliques utilises comme inhibiteurs d'agregation plaquettaire

Publications (1)

Publication Number Publication Date
SK120895A3 true SK120895A3 (en) 1996-06-05

Family

ID=26302668

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1208-95A SK120895A3 (en) 1993-03-29 1994-03-28 Pyridine derivatives, process for preparing the same and intermediate products in this process and pharmaceutical compositions containing them

Country Status (26)

Country Link
US (1) US5556977A (fr)
EP (2) EP0825184B1 (fr)
JP (1) JPH08508291A (fr)
KR (1) KR100231089B1 (fr)
CN (1) CN1120334A (fr)
AT (2) ATE202345T1 (fr)
AU (1) AU692438B2 (fr)
BR (1) BR9406613A (fr)
CA (1) CA2156070A1 (fr)
CZ (1) CZ250995A3 (fr)
DE (2) DE69427548T2 (fr)
DK (2) DK0825184T3 (fr)
ES (2) ES2119184T3 (fr)
FI (1) FI954616A7 (fr)
GB (1) GB9406143D0 (fr)
GR (2) GR3027751T3 (fr)
HU (2) HUT72088A (fr)
IL (1) IL109144A (fr)
NO (1) NO305244B1 (fr)
NZ (1) NZ262941A (fr)
PL (1) PL310889A1 (fr)
PT (1) PT825184E (fr)
SK (1) SK120895A3 (fr)
TW (1) TW276254B (fr)
WO (1) WO1994022834A1 (fr)
ZW (1) ZW4294A1 (fr)

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FR2734818B1 (fr) * 1995-06-01 1998-07-10 Zeneca Ltd Acide (-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazine-1-yl- phenoxy}-butyrique, procede pour sa preparation et composition pharmaceutique le contenant
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US5990107A (en) * 1996-06-28 1999-11-23 Merck & Co., Inc. Fibrinogen receptor antagonist prodrugs
US5854245A (en) * 1996-06-28 1998-12-29 Merck & Co., Inc. Fibrinogen receptor antagonists
US5932582A (en) * 1996-06-28 1999-08-03 Merck & Co., Inc. Fibrinogen receptor antagonist prodrugs
EP0912182A4 (fr) * 1996-06-28 1999-12-29 Merck & Co Inc Promedicaments antagonistes du recepteur de fibrinogene
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GB9821483D0 (en) 1998-10-03 1998-11-25 Glaxo Group Ltd Chemical compounds
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US6440972B1 (en) 1997-02-13 2002-08-27 Zeneca Limited Heterocyclic compounds useful as oxido-squalene cyclase inhibitors
DK0966462T3 (da) 1997-02-13 2003-09-22 Astrazeneca Ab Heterocykliske forbindelser, der er egnede som oxidosqualencyklaseinhibitorer
GB9715895D0 (en) 1997-07-29 1997-10-01 Zeneca Ltd Heterocyclic compounds
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CA2331056A1 (fr) 1998-05-12 1999-12-02 Wyeth Diphenyles 2,3,5-substitues utiles pour le traitement de la resistance insulinique et de l'hyperglycemie
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US6110963A (en) * 1998-05-12 2000-08-29 American Home Products Corporation Aryl-oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
US6699896B1 (en) 1998-05-12 2004-03-02 Wyeth Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
US6232322B1 (en) 1998-05-12 2001-05-15 American Home Products Corporation Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
DE69917278T2 (de) 1998-07-31 2005-05-19 Eli Lilly And Co., Indianapolis Heterocyclyl sulphonamid derivate
GB9902989D0 (en) 1999-02-11 1999-03-31 Zeneca Ltd Heterocyclic derivatives
WO2000063161A1 (fr) * 1999-04-19 2000-10-26 Coelacanth Corporation Agonistes ppar-(gamma) en tant qu'agents de traitement du diabete de type ii
US6310081B1 (en) 1999-05-10 2001-10-30 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
ATE502928T1 (de) 2000-11-01 2011-04-15 Millennium Pharm Inc Stickstoffhaltige heterozyklische verbindungen und verfahren zu deren herstellung
DE202011000090U1 (de) 2011-01-14 2011-04-21 E-LEAD ELECTRONIC CO., LTD., Shengang Shiang Fahrzeug-Audiosystem mit auswechselbarem Plug-In-Computer
JP7065951B2 (ja) 2017-09-22 2022-05-12 ジュビラント エピパッド エルエルシー Ｐａｄ阻害剤としての複素環式化合物
WO2019077631A1 (fr) 2017-10-18 2019-04-25 Jubilant Biosys Limited Composés imidazo-pyridine à utiliser en tant qu'inhibiteurs de pad
EP3707135A1 (fr) 2017-11-06 2020-09-16 Jubilant Prodel LLC Dérivés de pyrimidine utilisés en tant qu'inhibiteurs de l'activation de pd1/pd-l1
IL274762B2 (en) 2017-11-24 2023-10-01 Jubilant Episcribe Llc Novel heterocyclic compounds as prmt5 inhibitors
WO2019175897A1 (fr) 2018-03-13 2019-09-19 Jubilant Biosys Limited Composés bicycliques utilisés en tant qu'inhibiteurs de l'interaction/activation de pd1/pd-l1

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Also Published As

Publication number Publication date
IL109144A (en) 2000-02-29
CN1120334A (zh) 1996-04-10
NO953837D0 (no) 1995-09-28
GB9406143D0 (en) 1994-05-18
ES2119184T3 (es) 1998-10-01
DK0825184T3 (da) 2001-09-10
PL310889A1 (en) 1996-01-08
TW276254B (fr) 1996-05-21
DE69411900D1 (de) 1998-08-27
AU692438B2 (en) 1998-06-11
DE69427548D1 (de) 2001-07-26
PT825184E (pt) 2001-11-30
FI954616A0 (fi) 1995-09-28
EP0691959B1 (fr) 1998-07-22
ES2159798T3 (es) 2001-10-16
ATE168678T1 (de) 1998-08-15
EP0825184A1 (fr) 1998-02-25
EP0825184B1 (fr) 2001-06-20
GR3027751T3 (en) 1998-11-30
DK0691959T3 (da) 1999-04-26
GR3036640T3 (en) 2001-12-31
ZW4294A1 (en) 1994-12-21
NO953837L (no) 1995-09-28
EP0691959A1 (fr) 1996-01-17
FI954616L (fi) 1995-09-28
US5556977A (en) 1996-09-17
IL109144A0 (en) 1994-06-24
KR100231089B1 (ko) 1999-11-15
BR9406613A (pt) 1996-02-06
DE69427548T2 (de) 2002-04-18
FI954616A7 (fi) 1995-09-28
HU211336A9 (en) 1995-11-28
HUT72088A (en) 1996-03-28
CZ250995A3 (en) 1996-01-17
JPH08508291A (ja) 1996-09-03
DE69411900T2 (de) 1998-12-10
NO305244B1 (no) 1999-04-26
CA2156070A1 (fr) 1994-10-13
AU6288994A (en) 1994-10-24
NZ262941A (en) 1997-07-27
HU9502290D0 (en) 1995-10-30
WO1994022834A1 (fr) 1994-10-13
ATE202345T1 (de) 2001-07-15

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