SI1362864T1 - Nov postopek za sintezo perindoprila in njegovih farmacevtsko sprejemljivih soli - Google Patents
Nov postopek za sintezo perindoprila in njegovih farmacevtsko sprejemljivih soliInfo
- Publication number
- SI1362864T1 SI1362864T1 SI200330844T SI200330844T SI1362864T1 SI 1362864 T1 SI1362864 T1 SI 1362864T1 SI 200330844 T SI200330844 T SI 200330844T SI 200330844 T SI200330844 T SI 200330844T SI 1362864 T1 SI1362864 T1 SI 1362864T1
- Authority
- SI
- Slovenia
- Prior art keywords
- perindopril
- synthesis
- pharmaceutically acceptable
- acceptable salts
- salts
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- IPVQLZZIHOAWMC-QXKUPLGCSA-N perindopril Chemical compound C1CCC[C@H]2C[C@@H](C(O)=O)N(C(=O)[C@H](C)N[C@@H](CCC)C(=O)OCC)[C@H]21 IPVQLZZIHOAWMC-QXKUPLGCSA-N 0.000 title 1
- 229960002582 perindopril Drugs 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03291600A EP1362864B1 (fr) | 2003-06-30 | 2003-06-30 | Nouveau procédé de synthèse du perindopril et de ses sels pharmaceutiquement acceptables |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1362864T1 true SI1362864T1 (sl) | 2007-08-31 |
Family
ID=29266055
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200330844T SI1362864T1 (sl) | 2003-06-30 | 2003-06-30 | Nov postopek za sintezo perindoprila in njegovih farmacevtsko sprejemljivih soli |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7220776B2 (sl) |
| EP (1) | EP1362864B1 (sl) |
| JP (1) | JP4347342B2 (sl) |
| CN (1) | CN100383159C (sl) |
| AR (1) | AR044943A1 (sl) |
| AT (1) | ATE360638T1 (sl) |
| AU (1) | AU2004255899B2 (sl) |
| CY (1) | CY1106471T1 (sl) |
| DE (1) | DE60313391T2 (sl) |
| DK (1) | DK1362864T3 (sl) |
| EA (1) | EA009458B1 (sl) |
| ES (1) | ES2286393T3 (sl) |
| MY (1) | MY136938A (sl) |
| NZ (1) | NZ544004A (sl) |
| PL (1) | PL211491B1 (sl) |
| PT (1) | PT1362864E (sl) |
| SI (1) | SI1362864T1 (sl) |
| WO (1) | WO2005005461A2 (sl) |
| ZA (1) | ZA200510324B (sl) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2551952A1 (en) | 2003-12-29 | 2005-07-21 | Sepracor Inc. | Pyrrole and pyrazole daao inhibitors |
| EP1987828A1 (en) | 2005-01-06 | 2008-11-05 | IPCA Laboratories Limited | salts of perindopril and their use in the therapy of hypertension |
| EP1904066B1 (en) | 2005-07-06 | 2018-05-23 | Sunovion Pharmaceuticals Inc. | COMBINATIONS OF ESZOPICLONE AND TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPTHALENAMINE OR TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPTHALENAMINE, for treating MENOPAUSE, perimenopause AND COGNITIVE DISORDERS |
| CA2636324C (en) | 2006-01-06 | 2012-03-20 | Sepracor Inc. | Cycloalkylamines as monoamine reuptake inhibitors |
| WO2007081542A2 (en) | 2006-01-06 | 2007-07-19 | Sepracor Inc. | Tetralone-based monoamine reuptake inhibitors |
| DK2013835T3 (en) | 2006-03-31 | 2015-12-14 | Sunovion Pharmaceuticals Inc | Preparation of chiral amides and AMINES |
| US7884124B2 (en) | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
| JP2008019214A (ja) * | 2006-07-13 | 2008-01-31 | Shiono Chemical Co Ltd | ペリンドプリルまたはその誘導体の製造方法 |
| US7902252B2 (en) | 2007-01-18 | 2011-03-08 | Sepracor, Inc. | Inhibitors of D-amino acid oxidase |
| RU2470011C2 (ru) | 2007-05-31 | 2012-12-20 | Сепракор Инк. | Циклоалкиламины, содержащие в качестве заместителя фенил, как ингибиторы обратного захвата моноаминов |
| PH12018502155B1 (en) | 2016-04-20 | 2024-03-27 | Servier Lab | Pharmaceutical composition comprising a beta blocker, a converting enzyme inhibitor and an antihypertensive or an nsaid |
| CN111116709B (zh) * | 2019-12-31 | 2022-06-24 | 北京鑫开元医药科技有限公司 | 一种培哚普利制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2620709B1 (fr) * | 1987-09-17 | 1990-09-07 | Adir | Procede de synthese industrielle du perindopril et de ses principaux intermediaires de synthese |
| ATE294814T1 (de) * | 2003-03-12 | 2005-05-15 | Servier Lab | Verfahren für die synthese von perindopril und seiner pharmazeutischen annehmbaren salzen |
| SI1367061T1 (sl) * | 2003-06-30 | 2006-04-30 | Servier Lab | Nov postopek za sintezo perindoprila in njegovih farmacevtsko sprejemljivih soli |
-
2003
- 2003-06-30 PT PT03291600T patent/PT1362864E/pt unknown
- 2003-06-30 AT AT03291600T patent/ATE360638T1/de active
- 2003-06-30 SI SI200330844T patent/SI1362864T1/sl unknown
- 2003-06-30 ES ES03291600T patent/ES2286393T3/es not_active Expired - Lifetime
- 2003-06-30 DE DE60313391T patent/DE60313391T2/de not_active Expired - Lifetime
- 2003-06-30 EP EP03291600A patent/EP1362864B1/fr not_active Expired - Lifetime
- 2003-06-30 DK DK03291600T patent/DK1362864T3/da active
-
2004
- 2004-06-28 AU AU2004255899A patent/AU2004255899B2/en not_active Ceased
- 2004-06-28 JP JP2006515296A patent/JP4347342B2/ja not_active Expired - Fee Related
- 2004-06-28 PL PL379630A patent/PL211491B1/pl unknown
- 2004-06-28 US US10/562,950 patent/US7220776B2/en not_active Expired - Fee Related
- 2004-06-28 WO PCT/FR2004/001638 patent/WO2005005461A2/fr not_active Ceased
- 2004-06-28 EA EA200501900A patent/EA009458B1/ru not_active IP Right Cessation
- 2004-06-28 MY MYPI20042539A patent/MY136938A/en unknown
- 2004-06-28 NZ NZ544004A patent/NZ544004A/xx not_active IP Right Cessation
- 2004-06-28 ZA ZA200510324A patent/ZA200510324B/xx unknown
- 2004-06-28 CN CNB2004800163249A patent/CN100383159C/zh not_active Expired - Fee Related
- 2004-06-29 AR ARP040102276A patent/AR044943A1/es not_active Application Discontinuation
-
2007
- 2007-05-16 CY CY20071100663T patent/CY1106471T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EA200501900A1 (ru) | 2006-06-30 |
| HK1089187A1 (zh) | 2006-11-24 |
| NZ544004A (en) | 2009-03-31 |
| US20060148884A1 (en) | 2006-07-06 |
| ES2286393T3 (es) | 2007-12-01 |
| CN100383159C (zh) | 2008-04-23 |
| PL379630A1 (pl) | 2006-10-30 |
| CY1106471T1 (el) | 2012-01-25 |
| US7220776B2 (en) | 2007-05-22 |
| AR044943A1 (es) | 2005-10-12 |
| DE60313391T2 (de) | 2008-01-17 |
| JP2008500263A (ja) | 2008-01-10 |
| CN1805972A (zh) | 2006-07-19 |
| EP1362864B1 (fr) | 2007-04-25 |
| ZA200510324B (en) | 2007-03-28 |
| PL211491B1 (pl) | 2012-05-31 |
| JP4347342B2 (ja) | 2009-10-21 |
| PT1362864E (pt) | 2007-07-23 |
| DK1362864T3 (da) | 2007-09-17 |
| WO2005005461A2 (fr) | 2005-01-20 |
| DE60313391D1 (de) | 2007-06-06 |
| AU2004255899A1 (en) | 2005-01-20 |
| WO2005005461A3 (fr) | 2005-03-31 |
| MY136938A (en) | 2008-11-28 |
| ATE360638T1 (de) | 2007-05-15 |
| EA009458B1 (ru) | 2007-12-28 |
| EP1362864A1 (fr) | 2003-11-19 |
| AU2004255899B2 (en) | 2008-03-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU4847001A (en) | Method for synthesis of perindopril and its pharmaceutically acceptable salts | |
| AU2001248470A1 (en) | Method for synthesis of perindopril and its pharmaceutically acceptable salts | |
| SI1420028T1 (sl) | Postopek za sintezo perindoprila in njegovih farmacevtsko sprejemljivih soli | |
| SI1362864T1 (sl) | Nov postopek za sintezo perindoprila in njegovih farmacevtsko sprejemljivih soli | |
| SI1367061T1 (sl) | Nov postopek za sintezo perindoprila in njegovih farmacevtsko sprejemljivih soli | |
| SI1348684T1 (sl) | Nov postopek sinteze (2s)-indolin-2-karboksilne kisline in uporaba pri sintezi perindoprila | |
| SI1380590T1 (sl) | Postopek za sintezo perindoprila in njenih farmacevtsko sprejemljivih soli | |
| SI1371659T1 (sl) | Nov postopek za sintezo perindoprila in njegovih farmacevtsko sprejemljivih soli | |
| SI1420029T1 (sl) | Postopek za sintezo perindoprila in njegovih farmacevtsko sprejemljivih soli | |
| SI1380591T1 (sl) | Nov postopek sinteze perindoprila in njegovih farmacevtsko sprejemljivih soli | |
| IL175657A0 (en) | Derivatives of dihydronepetalactone and method for preparation | |
| SI1367062T1 (sl) | Nov postopek sinteze perindoprila in njegovih farmacevtsko sprejemljivih soli | |
| SI1367063T1 (sl) | Nov postopek sinteze perindoprila in njegovih farmacevtsko sprejemljivih soli | |
| SI1422236T1 (sl) | Postopek za sintezo perindoprila in njegovih farmacevtsko sprejemljivih soli | |
| DK1321471T3 (da) | Ny syntesefremgangsmåde til perindopril og farmaceutisk acceptable salte heraf | |
| SI1403275T1 (sl) | Nov postopek sinteze perindoprila in njegovih farmacevtsko sprejemljivih soli | |
| SI1753720T1 (sl) | Postopek za pripravo perindoprila in njegovih soli | |
| SI1268424T1 (sl) | Postopek za sintezo perindoprila in njegovih farmacevtsko sprejemljivih soli | |
| HK1089179A (en) | Method for the synthesis of exocyclic derivatives of cycloalkyl-hydrazines and exocyclic derivatives of heterocycloalkyl-hydrazines |