RU2018118399A3 - - Google Patents
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- Publication number
- RU2018118399A3 RU2018118399A3 RU2018118399A RU2018118399A RU2018118399A3 RU 2018118399 A3 RU2018118399 A3 RU 2018118399A3 RU 2018118399 A RU2018118399 A RU 2018118399A RU 2018118399 A RU2018118399 A RU 2018118399A RU 2018118399 A3 RU2018118399 A3 RU 2018118399A3
- Authority
- RU
- Russia
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15382523.7 | 2015-10-23 | ||
| EP15382523 | 2015-10-23 | ||
| PCT/EP2016/001742 WO2017067664A1 (en) | 2015-10-23 | 2016-10-21 | Oxa-diazaspiro compounds having activity against pain |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2018118399A RU2018118399A (ru) | 2019-11-25 |
| RU2018118399A3 true RU2018118399A3 (ru) | 2020-01-31 |
Family
ID=54364221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2018118399A RU2018118399A (ru) | 2015-10-23 | 2016-10-21 | Оксадиазаспиросоединения, обладающие активностью против боли |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US10689398B2 (ru) |
| EP (1) | EP3365346B1 (ru) |
| JP (1) | JP6884973B2 (ru) |
| KR (1) | KR20180073638A (ru) |
| CN (1) | CN108349998B (ru) |
| AR (1) | AR106448A1 (ru) |
| AU (1) | AU2016343551A1 (ru) |
| BR (1) | BR112018007269A2 (ru) |
| CA (1) | CA2999925A1 (ru) |
| CO (1) | CO2018004803A2 (ru) |
| CY (1) | CY1122708T1 (ru) |
| DK (1) | DK3365346T3 (ru) |
| ES (1) | ES2775522T3 (ru) |
| HR (1) | HRP20200309T1 (ru) |
| HU (1) | HUE047997T2 (ru) |
| IL (1) | IL258370A (ru) |
| LT (1) | LT3365346T (ru) |
| MA (1) | MA43158B1 (ru) |
| ME (1) | ME03636B (ru) |
| MX (1) | MX2018004777A (ru) |
| PH (1) | PH12018500682A1 (ru) |
| PL (1) | PL3365346T3 (ru) |
| PT (1) | PT3365346T (ru) |
| RS (1) | RS59956B1 (ru) |
| RU (1) | RU2018118399A (ru) |
| SG (1) | SG11201802988XA (ru) |
| SI (1) | SI3365346T1 (ru) |
| SM (1) | SMT202000128T1 (ru) |
| TN (1) | TN2018000091A1 (ru) |
| TW (1) | TW201731853A (ru) |
| WO (1) | WO2017067664A1 (ru) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201615643A (zh) | 2014-06-02 | 2016-05-01 | 伊史帝夫博士實驗室股份有限公司 | 具有多重模式抗疼痛活性之１－氧雜－４，９－二氮雜螺十一烷化合物之烷基與芳基衍生物 |
| SI3365346T1 (sl) | 2015-10-23 | 2020-04-30 | Esteve Pharmaceuticals, S.A. | Spojine oksa diazaspiro s protibolečinskim delovanjem |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3481942A (en) | 1968-09-06 | 1969-12-02 | Smithkline Corp | Oxa-diazaspiro(4.5)decane compounds |
| US4353900A (en) * | 1981-10-19 | 1982-10-12 | Syntex (U.S.A.) Inc. | 9-(Arylalkyl or aroylalkyl)-1-oxa-4,9-diazaspiro(5.5)undecan-3-ones |
| WO1993013101A1 (fr) * | 1991-12-27 | 1993-07-08 | Yoshitomi Pharmaceutical Industries, Ltd. | Compose de pyridonecarboxylate, son utilisation pharmaceutique et compose spiro |
| US6114541A (en) | 1997-03-10 | 2000-09-05 | Hoffmann-La Roche Inc. | Method for the preparation of α-Bromo-Lactam derivatives |
| EP1461339B1 (en) | 2001-12-28 | 2010-04-28 | Acadia Pharmaceuticals Inc. | Spiroazacyclic compounds as monoamine receptor modulators |
| EP1692085A4 (en) * | 2003-11-07 | 2010-10-13 | Novartis Vaccines & Diagnostic | INHIBITION OF FGFR3 AND TREATMENT OF MULTIPLE MYELOMA |
| EP1634873A1 (en) | 2004-08-27 | 2006-03-15 | Laboratorios Del Dr. Esteve, S.A. | Sigma receptor inhibitors |
| DE102005030051A1 (de) | 2005-06-27 | 2006-12-28 | Grünenthal GmbH | Substituierte 1-Oxa-3,8-diazaspiro[4,5]-decan-2-on-Verbindungen und deren Verwendung zur Herstellung von Arzneimitteln |
| DK1961744T3 (da) | 2005-11-18 | 2013-07-15 | Ono Pharmaceutical Co | Forbindelse indeholdende basiske grupper samt anvendelse deraf |
| EP1829869A1 (en) | 2006-03-02 | 2007-09-05 | Laboratorios Del Dr. Esteve, S.A. | 4,5,6,7-Tetrahydrobenzo[b]thiophene derivatives and their use as sigma receptor ligands |
| WO2007124136A1 (en) | 2006-04-19 | 2007-11-01 | Acadia Pharmaceuticals, Inc. | Use of 4-amino-piperidines for treating sleep disorders |
| EP1847542A1 (en) | 2006-04-21 | 2007-10-24 | Laboratorios del Dr. Esteve S.A. | Spiro[benzopyran] or spiro[benzofuran] derivatives which inhibit the sigma receptor |
| ES2541133T3 (es) | 2007-03-01 | 2015-07-16 | Mitsubishi Tanabe Pharma Corporation | Compuesto de bencimidazol y uso farmacéutico del mismo |
| EP1982714A1 (en) | 2007-04-16 | 2008-10-22 | Laboratorios del Dr. Esteve S.A. | Pyrano-pyrazole-amines |
| EP2020414A1 (en) | 2007-06-20 | 2009-02-04 | Laboratorios del Dr. Esteve S.A. | spiro[piperidine-4,4'-thieno[3,2-c]pyran] derivatives and related compounds as inhibitors of the sigma receptor for the treatment of psychosis |
| WO2009032667A1 (en) | 2007-08-29 | 2009-03-12 | Smithkline Beecham Corporation | Thiazole and oxazole kinase inhibitors |
| EP2070933A1 (en) | 2007-12-07 | 2009-06-17 | Laboratorios del Dr. Esteve S.A. | Tricyclic triazolic compounds |
| PT2242759E (pt) | 2008-02-06 | 2012-12-17 | Astrazeneca Ab | Compostos |
| EP2460347A4 (en) | 2009-10-25 | 2014-03-12 | Lg Electronics Inc | METHOD FOR PROCESSING BROADCAST AND BROADCAST RECEIVER PROGRAM INFORMATION |
| AU2012229187B2 (en) * | 2011-03-14 | 2016-11-10 | Vertex Pharmaceuticals Incorporated | Morpholine-spirocyclic piperidine amides as modulators of ion channels |
| WO2012125813A1 (en) | 2011-03-16 | 2012-09-20 | Access Business Group International Llc | Humidifier with ultraviolet disinfection |
| WO2013028447A1 (en) | 2011-08-19 | 2013-02-28 | Glaxosmithkline Llc | Fatty acid synthase inhibitors |
| WO2015017305A1 (en) | 2013-07-31 | 2015-02-05 | Merck Sharp & Dohme Corp | Inhibitors of the renal outer medullary potassium channel |
| JP2017100951A (ja) | 2014-04-04 | 2017-06-08 | 大正製薬株式会社 | オキサゾリジノン及びオキサジナノン誘導体 |
| TW201615642A (zh) | 2014-06-02 | 2016-05-01 | 伊史帝夫博士實驗室股份有限公司 | 具有多重模式抗疼痛活性的１－氧雜－４，９－二氮雜螺十一烷化合物之醯胺衍生物 |
| TW201615643A (zh) * | 2014-06-02 | 2016-05-01 | 伊史帝夫博士實驗室股份有限公司 | 具有多重模式抗疼痛活性之１－氧雜－４，９－二氮雜螺十一烷化合物之烷基與芳基衍生物 |
| TWI685497B (zh) | 2014-06-02 | 2020-02-21 | 西班牙商伊史帝夫製藥公司 | 具有多重模式抗疼痛活性的１-氧雜-４,９-二氮雜螺十一烷化合物之烷基衍生物 |
| US10022359B2 (en) | 2014-11-21 | 2018-07-17 | Esteve Pharmaceuticals, S.A. | 1,9-diazaspiro undecane compounds having multimodal activity against pain |
| SI3365346T1 (sl) | 2015-10-23 | 2020-04-30 | Esteve Pharmaceuticals, S.A. | Spojine oksa diazaspiro s protibolečinskim delovanjem |
-
2016
- 2016-10-21 SI SI201630655T patent/SI3365346T1/sl unknown
- 2016-10-21 ES ES16784795T patent/ES2775522T3/es active Active
- 2016-10-21 RS RS20200216A patent/RS59956B1/sr unknown
- 2016-10-21 PL PL16784795T patent/PL3365346T3/pl unknown
- 2016-10-21 ME MEP-2020-39A patent/ME03636B/me unknown
- 2016-10-21 EP EP16784795.3A patent/EP3365346B1/en active Active
- 2016-10-21 DK DK16784795.3T patent/DK3365346T3/da active
- 2016-10-21 RU RU2018118399A patent/RU2018118399A/ru not_active Application Discontinuation
- 2016-10-21 AU AU2016343551A patent/AU2016343551A1/en not_active Abandoned
- 2016-10-21 LT LTEP16784795.3T patent/LT3365346T/lt unknown
- 2016-10-21 CA CA2999925A patent/CA2999925A1/en not_active Abandoned
- 2016-10-21 WO PCT/EP2016/001742 patent/WO2017067664A1/en not_active Ceased
- 2016-10-21 AR ARP160103229A patent/AR106448A1/es unknown
- 2016-10-21 SM SM20200128T patent/SMT202000128T1/it unknown
- 2016-10-21 MA MA43158A patent/MA43158B1/fr unknown
- 2016-10-21 BR BR112018007269-9A patent/BR112018007269A2/pt not_active Application Discontinuation
- 2016-10-21 CN CN201680061752.6A patent/CN108349998B/zh active Active
- 2016-10-21 TW TW105134203A patent/TW201731853A/zh unknown
- 2016-10-21 PT PT167847953T patent/PT3365346T/pt unknown
- 2016-10-21 HU HUE16784795A patent/HUE047997T2/hu unknown
- 2016-10-21 TN TNP/2018/000091A patent/TN2018000091A1/en unknown
- 2016-10-21 KR KR1020187014463A patent/KR20180073638A/ko not_active Withdrawn
- 2016-10-21 HR HRP20200309TT patent/HRP20200309T1/hr unknown
- 2016-10-21 MX MX2018004777A patent/MX2018004777A/es unknown
- 2016-10-21 US US15/769,754 patent/US10689398B2/en active Active
- 2016-10-21 SG SG11201802988XA patent/SG11201802988XA/en unknown
- 2016-10-21 JP JP2018519862A patent/JP6884973B2/ja active Active
-
2018
- 2018-03-26 IL IL258370A patent/IL258370A/en unknown
- 2018-03-27 PH PH12018500682A patent/PH12018500682A1/en unknown
- 2018-05-04 CO CONC2018/0004803A patent/CO2018004803A2/es unknown
-
2020
- 2020-02-27 CY CY20201100183T patent/CY1122708T1/el unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20200813 |