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RU2018100967A3 - - Google Patents

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Publication number
RU2018100967A3
RU2018100967A3 RU2018100967A RU2018100967A RU2018100967A3 RU 2018100967 A3 RU2018100967 A3 RU 2018100967A3 RU 2018100967 A RU2018100967 A RU 2018100967A RU 2018100967 A RU2018100967 A RU 2018100967A RU 2018100967 A3 RU2018100967 A3 RU 2018100967A3
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RU
Russia
Application number
RU2018100967A
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RU2018100967A (ru
RU2717830C2 (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Publication of RU2018100967A publication Critical patent/RU2018100967A/ru
Publication of RU2018100967A3 publication Critical patent/RU2018100967A3/ru
Application granted granted Critical
Publication of RU2717830C2 publication Critical patent/RU2717830C2/ru

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
RU2018100967A 2015-07-15 2016-07-14 Способ получения азотсодержащего гетероциклического соединения и его промежуточного соединения RU2717830C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2015141034A JP6412471B2 (ja) 2015-07-15 2015-07-15 含窒素複素環化合物の製造方法およびその中間体
JP2015-141034 2015-07-15
PCT/JP2016/070758 WO2017010535A1 (ja) 2015-07-15 2016-07-14 含窒素複素環化合物の製造方法およびその中間体

Publications (3)

Publication Number Publication Date
RU2018100967A RU2018100967A (ru) 2019-08-16
RU2018100967A3 true RU2018100967A3 (ru) 2019-08-16
RU2717830C2 RU2717830C2 (ru) 2020-03-26

Family

ID=57758235

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2018100967A RU2717830C2 (ru) 2015-07-15 2016-07-14 Способ получения азотсодержащего гетероциклического соединения и его промежуточного соединения

Country Status (20)

Country Link
US (2) US10435377B2 (ru)
EP (1) EP3323811B1 (ru)
JP (1) JP6412471B2 (ru)
KR (1) KR102032140B1 (ru)
CN (1) CN107848987B (ru)
AU (1) AU2016294197B2 (ru)
BR (1) BR112018000759A2 (ru)
CA (1) CA2992403C (ru)
DK (1) DK3323811T3 (ru)
ES (1) ES2729958T3 (ru)
IL (1) IL256809B (ru)
MX (1) MX2018000459A (ru)
NZ (1) NZ738953A (ru)
PL (1) PL3323811T3 (ru)
RU (1) RU2717830C2 (ru)
SG (1) SG11201800245QA (ru)
TR (1) TR201909774T4 (ru)
TW (1) TWI711605B (ru)
WO (1) WO2017010535A1 (ru)
ZA (1) ZA201800269B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202027749A (zh) 2018-10-12 2020-08-01 日商富士軟片股份有限公司 急性骨髓性白血病用抗腫瘤劑
EP3875088A4 (en) * 2018-10-31 2021-12-29 FUJIFILM Corporation Package for medical composition containing anti-tumor agent
JPWO2020090968A1 (ja) * 2018-10-31 2021-09-16 富士フイルム株式会社 抗腫瘍剤を含む造粒物
TW202045174A (zh) 2019-02-28 2020-12-16 日商富士軟片股份有限公司 組合醫藥
IL313670A (en) 2021-12-30 2024-08-01 Biomea Fusion Inc Pyrazine compounds as inhibitors of FLT3

Family Cites Families (22)

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GB8928839D0 (en) 1989-12-21 1990-02-28 Beecham Group Plc Novel compounds
UY27487A1 (es) 2001-10-17 2003-05-30 Boehringer Ingelheim Pharma Derivados de pirimidina, medicamentos que contienen estos compuestos, su empleo y procedimiento para su preparación
SG137989A1 (en) 2005-06-08 2008-01-28 Rigel Pharmaceuticals Inc Compositions and methods for inhibition of the JAK pathway
US20060281755A1 (en) 2005-06-10 2006-12-14 Baumann Christian A Synergistic modulation of flt3 kinase using aminopyrimidines kinase modulators
US8071768B2 (en) * 2005-06-10 2011-12-06 Janssen Pharmaceutica, N.V. Alkylquinoline and alkylquinazoline kinase modulators
CA2833852C (en) 2005-11-11 2014-10-21 Boehringer Ingelheim International Gmbh Quinazoline derivatives for the treatment of cancer diseases
PL2001892T3 (pl) 2006-03-17 2013-09-30 Ambit Biosciences Corp Imidazolotiazolowe związki do leczenia chorób proliferacyjnych
EP2022785A1 (en) * 2007-06-20 2009-02-11 Bayer Schering Pharma Aktiengesellschaft Alkynylpyrimidines as Tie2 kinase inhibitors
CA2713553A1 (en) 2008-02-01 2009-08-06 Akinion Pharmaceuticals Ab Pyrazine derivatives and their use as protein kinase inhibitors
NZ588029A (en) 2008-03-14 2012-12-21 Allergan Inc Immuno-based botulinum toxin serotype a activity assays
BRPI0908637B8 (pt) 2008-05-21 2021-05-25 Ariad Pharma Inc composto e composição farmacêutica do mesmo
EP2440559B1 (en) 2009-05-05 2018-01-10 Dana-Farber Cancer Institute, Inc. Egfr inhibitors and methods of treating disorders
US9290485B2 (en) 2010-08-04 2016-03-22 Novartis Ag N-((6-amino-pyridin-3-yl)methyl)-heteroaryl-carboxamides
EP2635285B1 (en) 2010-11-01 2017-05-03 Celgene Avilomics Research, Inc. Heteroaryl compounds and uses thereof
JP5957003B2 (ja) 2010-11-10 2016-07-27 セルジーン アヴィロミクス リサーチ, インコーポレイテッド 変異体選択的egfr阻害剤およびその使用
EP2694486B1 (en) 2011-04-01 2018-01-10 University of Utah Research Foundation Substituted n-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs as tyrosine receptor kinase btk inhibitors
US9169209B2 (en) 2011-05-04 2015-10-27 Forma Tm, Llc Compounds and compositions for the inhibition of NAMPT
JP2013157540A (ja) 2012-01-31 2013-08-15 Toshiba Corp 半導体装置およびその製造方法
TWI596089B (zh) * 2012-04-17 2017-08-21 富士軟片股份有限公司 含氮雜環化合物或其鹽
DK3059227T3 (da) 2013-10-16 2019-08-26 Fujifilm Corp Salt af en nitrogen-holdig heterocyklisk forbindelse eller krystal deraf, farmaceutisk sammensætning og flt3-hæmmer
KR20150056683A (ko) 2013-11-15 2015-05-27 (주) 제일피앤티 대전 방지 필름 및 이를 이용한 쉴드 백
WO2016027904A1 (ja) 2014-08-22 2016-02-25 富士フイルム株式会社 Flt3変異陽性癌を処置するための医薬組成物、変異型flt3阻害剤およびそれらの応用

Also Published As

Publication number Publication date
ES2729958T3 (es) 2019-11-07
CA2992403C (en) 2019-12-31
HK1245268A1 (zh) 2018-08-24
IL256809A (en) 2018-03-29
SG11201800245QA (en) 2018-02-27
US20180127382A1 (en) 2018-05-10
JP6412471B2 (ja) 2018-10-24
EP3323811A1 (en) 2018-05-23
CN107848987B (zh) 2020-10-23
BR112018000759A2 (pt) 2018-09-04
RU2018100967A (ru) 2019-08-16
AU2016294197A1 (en) 2018-01-25
WO2017010535A1 (ja) 2017-01-19
US10562862B2 (en) 2020-02-18
MX2018000459A (es) 2018-09-07
TW201706254A (zh) 2017-02-16
CN107848987A (zh) 2018-03-27
KR20180011848A (ko) 2018-02-02
US10435377B2 (en) 2019-10-08
KR102032140B1 (ko) 2019-10-15
RU2717830C2 (ru) 2020-03-26
DK3323811T3 (da) 2019-07-22
ZA201800269B (en) 2019-05-29
EP3323811B1 (en) 2019-05-08
NZ738953A (en) 2019-06-28
AU2016294197B2 (en) 2018-07-26
TR201909774T4 (tr) 2019-07-22
CA2992403A1 (en) 2017-01-19
EP3323811A4 (en) 2018-05-23
PL3323811T3 (pl) 2019-09-30
IL256809B (en) 2019-06-30
US20190169133A1 (en) 2019-06-06
TWI711605B (zh) 2020-12-01
JP2017019760A (ja) 2017-01-26

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