[go: up one dir, main page]

PL3323811T3 - Sposób wytwarzania heterocyklicznego związku zawierającego azot oraz związku pośredniego heterocyklicznego związku zawierającego azot - Google Patents

Sposób wytwarzania heterocyklicznego związku zawierającego azot oraz związku pośredniego heterocyklicznego związku zawierającego azot

Info

Publication number
PL3323811T3
PL3323811T3 PL16824515T PL16824515T PL3323811T3 PL 3323811 T3 PL3323811 T3 PL 3323811T3 PL 16824515 T PL16824515 T PL 16824515T PL 16824515 T PL16824515 T PL 16824515T PL 3323811 T3 PL3323811 T3 PL 3323811T3
Authority
PL
Poland
Prior art keywords
nitrogen
heterocyclic compound
containing heterocyclic
production method
compound
Prior art date
Application number
PL16824515T
Other languages
English (en)
Inventor
Yusuke Nagato
Shinsuke Mizumoto
Tatsuya Murakami
Tomoyuki Tanaka
Original Assignee
Fujifilm Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Corporation filed Critical Fujifilm Corporation
Publication of PL3323811T3 publication Critical patent/PL3323811T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL16824515T 2015-07-15 2016-07-14 Sposób wytwarzania heterocyklicznego związku zawierającego azot oraz związku pośredniego heterocyklicznego związku zawierającego azot PL3323811T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2015141034A JP6412471B2 (ja) 2015-07-15 2015-07-15 含窒素複素環化合物の製造方法およびその中間体
EP16824515.7A EP3323811B1 (en) 2015-07-15 2016-07-14 Production method for nitrogen-containing heterocyclic compound, and intermediate of said nitrogen-containing heterocyclic compound
PCT/JP2016/070758 WO2017010535A1 (ja) 2015-07-15 2016-07-14 含窒素複素環化合物の製造方法およびその中間体

Publications (1)

Publication Number Publication Date
PL3323811T3 true PL3323811T3 (pl) 2019-09-30

Family

ID=57758235

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16824515T PL3323811T3 (pl) 2015-07-15 2016-07-14 Sposób wytwarzania heterocyklicznego związku zawierającego azot oraz związku pośredniego heterocyklicznego związku zawierającego azot

Country Status (20)

Country Link
US (2) US10435377B2 (pl)
EP (1) EP3323811B1 (pl)
JP (1) JP6412471B2 (pl)
KR (1) KR102032140B1 (pl)
CN (1) CN107848987B (pl)
AU (1) AU2016294197B2 (pl)
BR (1) BR112018000759A2 (pl)
CA (1) CA2992403C (pl)
DK (1) DK3323811T3 (pl)
ES (1) ES2729958T3 (pl)
IL (1) IL256809B (pl)
MX (1) MX2018000459A (pl)
NZ (1) NZ738953A (pl)
PL (1) PL3323811T3 (pl)
RU (1) RU2717830C2 (pl)
SG (1) SG11201800245QA (pl)
TR (1) TR201909774T4 (pl)
TW (1) TWI711605B (pl)
WO (1) WO2017010535A1 (pl)
ZA (1) ZA201800269B (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202027749A (zh) 2018-10-12 2020-08-01 日商富士軟片股份有限公司 急性骨髓性白血病用抗腫瘤劑
WO2020090969A1 (ja) * 2018-10-31 2020-05-07 富士フイルム株式会社 抗腫瘍剤を含む医薬組成物の包装体
WO2020090968A1 (ja) * 2018-10-31 2020-05-07 富士フイルム株式会社 抗腫瘍剤を含む造粒物
TW202045174A (zh) 2019-02-28 2020-12-16 日商富士軟片股份有限公司 組合醫藥
US11945785B2 (en) 2021-12-30 2024-04-02 Biomea Fusion, Inc. Pyrazine compounds as inhibitors of FLT3

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8928839D0 (en) 1989-12-21 1990-02-28 Beecham Group Plc Novel compounds
ES2314106T3 (es) 2001-10-17 2009-03-16 BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG Derivados de pirimidina, agentes farmaceuticos que contiene dichos compuestos, uso y metodo para su obtencion.
RU2485106C2 (ru) 2005-06-08 2013-06-20 Райджел Фамэсьютикэлз, Инк. Соединения, проявляющие активность в отношении jak-киназы (варианты), способ лечения заболеваний, опосредованных jak-киназой, способ ингибирования активности jak-киназы (варианты), фармацевтическая композиция на основе указанных соединений
US8071768B2 (en) * 2005-06-10 2011-12-06 Janssen Pharmaceutica, N.V. Alkylquinoline and alkylquinazoline kinase modulators
US20060281755A1 (en) 2005-06-10 2006-12-14 Baumann Christian A Synergistic modulation of flt3 kinase using aminopyrimidines kinase modulators
JP5688877B2 (ja) 2005-11-11 2015-03-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 癌疾患の治療用キナゾリン誘導体
TWI409267B (zh) 2006-03-17 2013-09-21 Ambit Biosciences Corp 治療疾病用之咪唑并噻唑化合物
EP2022785A1 (en) * 2007-06-20 2009-02-11 Bayer Schering Pharma Aktiengesellschaft Alkynylpyrimidines as Tie2 kinase inhibitors
AU2009209633C1 (en) 2008-02-01 2014-01-23 Akinion Pharmaceuticals Ab Pyrazine derivatives and their use as protein kinase inhbitors
KR101609894B1 (ko) 2008-03-14 2016-04-08 알러간, 인코포레이티드 면역-기반 보툴리눔 독소 세로타입 a 활성 검정
PT2300013T (pt) 2008-05-21 2017-10-31 Ariad Pharma Inc Derivados de fósforo como inibidores de cinases
JP5918693B2 (ja) 2009-05-05 2016-05-18 ダナ ファーバー キャンサー インスティテュート インコーポレイテッド Egfr阻害剤及び疾患の治療方法
US9290485B2 (en) 2010-08-04 2016-03-22 Novartis Ag N-((6-amino-pyridin-3-yl)methyl)-heteroaryl-carboxamides
EP2635285B1 (en) 2010-11-01 2017-05-03 Celgene Avilomics Research, Inc. Heteroaryl compounds and uses thereof
US8796255B2 (en) 2010-11-10 2014-08-05 Celgene Avilomics Research, Inc Mutant-selective EGFR inhibitors and uses thereof
CN103889962B (zh) 2011-04-01 2017-05-03 犹他大学研究基金会 作为受体酪氨酸激酶btk抑制剂的取代的n‑(3‑(嘧啶‑4‑基)苯基)丙烯酰胺类似物
RU2616612C2 (ru) 2011-05-04 2017-04-18 ФОРМА ТиЭм, ЭлЭлСИ Новые соединения и композиции для ингибирования nampt
JP2013157540A (ja) 2012-01-31 2013-08-15 Toshiba Corp 半導体装置およびその製造方法
SI2840080T1 (en) * 2012-04-17 2018-03-30 Fujifilm Corporation Nitrogen-containing heterocyclic compound or salt thereof
PL3059227T3 (pl) * 2013-10-16 2019-11-29 Fujifilm Corp Sól heterocyklicznego związku zawierającego azot lub jej kryształ, kompozycja farmaceutyczna i inhibitor flt3
KR20150056683A (ko) 2013-11-15 2015-05-27 (주) 제일피앤티 대전 방지 필름 및 이를 이용한 쉴드 백
RU2727195C2 (ru) 2014-08-22 2020-07-21 Фуджифилм Корпорэйшн Фармацевтическая композиция для лечения злокачественной опухоли, положительной по мутации flt3, ингибитор мутантного flt3 и их применение

Also Published As

Publication number Publication date
SG11201800245QA (en) 2018-02-27
WO2017010535A1 (ja) 2017-01-19
CA2992403C (en) 2019-12-31
CN107848987B (zh) 2020-10-23
RU2018100967A (ru) 2019-08-16
DK3323811T3 (da) 2019-07-22
JP6412471B2 (ja) 2018-10-24
TW201706254A (zh) 2017-02-16
ZA201800269B (en) 2019-05-29
KR20180011848A (ko) 2018-02-02
US20180127382A1 (en) 2018-05-10
EP3323811B1 (en) 2019-05-08
US10562862B2 (en) 2020-02-18
AU2016294197A1 (en) 2018-01-25
EP3323811A1 (en) 2018-05-23
CN107848987A (zh) 2018-03-27
EP3323811A4 (en) 2018-05-23
NZ738953A (en) 2019-06-28
TWI711605B (zh) 2020-12-01
KR102032140B1 (ko) 2019-10-15
RU2717830C2 (ru) 2020-03-26
AU2016294197B2 (en) 2018-07-26
TR201909774T4 (tr) 2019-07-22
US10435377B2 (en) 2019-10-08
JP2017019760A (ja) 2017-01-26
US20190169133A1 (en) 2019-06-06
CA2992403A1 (en) 2017-01-19
IL256809B (en) 2019-06-30
MX2018000459A (es) 2018-09-07
ES2729958T3 (es) 2019-11-07
BR112018000759A2 (pt) 2018-09-04
HK1245268A1 (zh) 2018-08-24
IL256809A (en) 2018-03-29
RU2018100967A3 (pl) 2019-08-16

Similar Documents

Publication Publication Date Title
IL249009A0 (en) A method for making a fused heterocyclic compound
IL283289B (en) A method for the production of a new nitrogen-containing compound or a salt thereof and the production of an intermediate of a new nitrogen-containing compound or a salt thereof
EP3156397A4 (en) Nitrogen-containing heterocyclic compound
GB2557741B (en) Icariside compound, preperation method thereof, and application thereof
EP3144308A4 (en) Nitrogen-containing heterocyclic compound
PL3309138T3 (pl) Sposób koprodukcji 2,3,3,3-tetrafluoropropylenu i 1,3,3,3-tetrafluoropropylenu
ZA201800269B (en) Production method for nitrogen-containing heterocyclic compound, and intermediate of said nitrogen-containing heterocyclic compound
EP3153496A4 (en) Method for preparing azetidinone compound and intermediate of azetidinone compound
IL264307B (en) Production method for a pyrazole-amide compound
GB201904142D0 (en) Improved method of FT-IMS
SG11202004021RA (en) Production method for dihydroxyindoles
ZA201800967B (en) Nitrogen-containing heterocyclic compound
IL254890A0 (en) The tercyclic compound
IL250223B (en) A method for the preparation of the pyrimidine-1-ol compound, and its intermediates
GB2555726B (en) Urea production method
HUE057149T2 (hu) Mikromolekula vegyület, eljárás szintézisére és alkalmazására
GB201710285D0 (en) Method for producing nitrogen-containing pentafluorosulfanylbenzene compound
PL3307895T3 (pl) Sposób jednoczesnego wytwarzania biogazu i co najmniej jednego związku organicznego
EP3246322A4 (en) Furoxan compound, and manufacturing method for same
IL263091B (en) A method for the production of heterocyclic compounds
IL266902A (en) A method for the reduction of oxo-halogen compounds
PL3184872T3 (pl) Armatura do nawiercania i odpowiedni sposób wytwarzania
EP3130581A4 (en) Method for producing heterocyclic compound