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PL3583943T3 - Kompozycja farmaceutyczna - Google Patents

Kompozycja farmaceutyczna

Info

Publication number
PL3583943T3
PL3583943T3 PL18755023.1T PL18755023T PL3583943T3 PL 3583943 T3 PL3583943 T3 PL 3583943T3 PL 18755023 T PL18755023 T PL 18755023T PL 3583943 T3 PL3583943 T3 PL 3583943T3
Authority
PL
Poland
Prior art keywords
pharmaceutical composition
pharmaceutical
composition
Prior art date
Application number
PL18755023.1T
Other languages
English (en)
Inventor
Shinji Okada
Original Assignee
Taiho Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co., Ltd. filed Critical Taiho Pharmaceutical Co., Ltd.
Publication of PL3583943T3 publication Critical patent/PL3583943T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1611Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/04Nitro compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
PL18755023.1T 2017-02-15 2018-02-14 Kompozycja farmaceutyczna PL3583943T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017026203 2017-02-15
PCT/JP2018/005140 WO2018151177A1 (ja) 2017-02-15 2018-02-14 医薬組成物

Publications (1)

Publication Number Publication Date
PL3583943T3 true PL3583943T3 (pl) 2024-11-25

Family

ID=63169269

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18755023.1T PL3583943T3 (pl) 2017-02-15 2018-02-14 Kompozycja farmaceutyczna

Country Status (20)

Country Link
US (2) US11110062B2 (pl)
EP (1) EP3583943B1 (pl)
JP (1) JP6771594B2 (pl)
KR (2) KR20210135354A (pl)
CN (2) CN110312511B (pl)
AU (1) AU2018222163C1 (pl)
CA (1) CA3053739C (pl)
DK (1) DK3583943T3 (pl)
ES (1) ES2991062T3 (pl)
FI (1) FI3583943T3 (pl)
HU (1) HUE068810T2 (pl)
MA (1) MA47516A (pl)
MX (2) MX383728B (pl)
MY (1) MY194278A (pl)
PH (1) PH12019501873A1 (pl)
PL (1) PL3583943T3 (pl)
PT (1) PT3583943T (pl)
SG (1) SG11201907433TA (pl)
TW (1) TWI702951B (pl)
WO (1) WO2018151177A1 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3583943B1 (en) 2017-02-15 2024-09-18 Taiho Pharmaceutical Co., Ltd. Pharmaceutical composition
MA50251A (fr) * 2017-09-08 2021-06-02 Taiho Pharmaceutical Co Ltd Agent antitumoral et potentialisateur d'effet antitumoral
AU2019342447B2 (en) 2018-09-18 2025-05-29 Taiho Pharmaceutical Co., Ltd. Combination therapy of acylthiourea compound and abiraterone
TWI872203B (zh) 2020-02-14 2025-02-11 日商大鵬藥品工業股份有限公司 醯基硫脲化合物的製造方法
WO2022191683A1 (ko) 2021-03-12 2022-09-15 주식회사 엘지에너지솔루션 버스바 어셈블리, 이러한 버스바 어셈블리를 포함하는 배터리 팩 및 이러한 배터리 팩을 포함하는 자동차
US20230114887A1 (en) 2021-10-12 2023-04-13 Lg Energy Solution, Ltd. Battery pack and vehicle including the same

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254541A (en) 1991-11-15 1993-10-19 Merck Frosst Canada, Inc. (Quinolin-2-ylmethoxy)indole/cyclodextrin complex
CN1154070A (zh) * 1994-05-27 1997-07-09 荷兰发马克有限公司 药物组合物
TWI281915B (en) 1999-12-24 2007-06-01 Kirin Brewery Quinoline and quinazoline derivatives and drugs containing the same
WO2002032872A1 (fr) 2000-10-20 2002-04-25 Eisai Co., Ltd. Composes a noyau aromatique azote
AU2002313249B2 (en) 2001-06-22 2008-08-21 Kirin Pharma Kabushiki Kaisha Quinoline derivative and quinazoline derivate inhibiting self-phosphorylation of hepatocytus proliferator receptor, and medicinal composition containing the same
SE520606C2 (sv) 2001-06-26 2003-07-29 Flir Systems Ab Förfarande för att åstadkomma en spegelyta, samt spegel med sådan spegelyta
JP2003238592A (ja) 2001-12-13 2003-08-27 Japan Tobacco Inc 組織及び血管の再生のための医薬及びその方法
CN1448053A (zh) * 2003-04-22 2003-10-15 西安敬业生物药物科技有限公司 甲基托布津包络物农药制剂
PT2213661E (pt) 2003-09-26 2011-12-15 Exelixis Inc Moduladores de c-met e métodos de uso
AU2005217325B2 (en) 2004-02-27 2007-11-29 Eisai R & D Management Co., Ltd. Novel pyridine derivative and pyrimidine derivative (1)
WO2005105044A1 (en) * 2004-04-30 2005-11-10 Ranbaxy Laboratories Limited Process for making inclusion complex of sulfonylureas having improved aqueous solubility
WO2005121125A1 (en) 2004-06-09 2005-12-22 Pfizer Inc. Ether-linked heteroaryl compounds
US7173031B2 (en) 2004-06-28 2007-02-06 Bristol-Myers Squibb Company Pyrrolotriazine kinase inhibitors
CN100448053C (zh) * 2004-08-31 2008-12-31 清华大学 含有屏蔽掩膜支撑体的有机电致发光器件及其制备方法
AU2006229343A1 (en) 2005-03-28 2006-10-05 Kirin Pharma Kabushiki Kaisha Thienopyridine derivative, or quinoline derivative, or quinazoline derivative, having c-Met autophosphorylation inhibiting potency
US20080161305A1 (en) 2005-04-06 2008-07-03 Exelixis, Inc. C-Met Modulators and Methods of Use
US7728017B2 (en) 2005-11-30 2010-06-01 Vertex Pharmaceuticals Incorporated Inhibitors of c-Met and uses thereof
AU2008315746A1 (en) 2007-10-25 2009-04-30 Astrazeneca Ab Pyridine and pyrazine derivatives useful in the treatment of cell proliferative disorders
CN101491240A (zh) * 2008-01-25 2009-07-29 国家农产品保鲜工程技术研究中心(天津) 提高纳他霉素作用效率的方法
BRPI0906576A2 (pt) 2008-01-29 2015-07-07 Eisai R&D Man Co Ltd Composição farmacêutica, kit, uso de um composto, e, agente terapêutico para câncer
JP2011513427A (ja) 2008-03-06 2011-04-28 ジェネンテック, インコーポレイテッド c−met及びEGFRアンタゴニストの併用療法
CA2720552C (en) 2008-04-10 2016-06-14 Taiho Pharmaceutical Co., Ltd. Acylthiourea compound or salt thereof, and use thereof
UY31800A (es) 2008-05-05 2009-11-10 Smithkline Beckman Corp Metodo de tratamiento de cancer usando un inhibidor de cmet y axl y un inhibidor de erbb
US20110104161A1 (en) 2008-05-14 2011-05-05 Burgess Teresa L Combinations vegf(r) inhibitors and hepatocyte growth factor (c-met) inhibitors for the treatment of cancer
UY32049A (es) 2008-08-14 2010-03-26 Takeda Pharmaceutical Inhibidores de cmet
AU2009314072C1 (en) * 2008-11-15 2016-11-10 Melinta Subsidiary Corp. Antimicrobial compositions
WO2010093789A2 (en) 2009-02-12 2010-08-19 Arqule, Inc. Combinational compositions and methods for treatment of cancer
CN101926808A (zh) 2009-06-25 2010-12-29 积华药业有限公司 氨基葡萄糖制剂
AU2011269788B2 (en) 2010-02-03 2015-12-10 Incyte Holdings Corporation Imidazo[1,2-b][1,2,4]triazines as c-Met inhibitors
EA201690998A1 (ru) 2010-05-17 2017-01-30 Инкозен Терапьютикс Пвт. Лтд. НОВЫЕ СОЕДИНЕНИЯ 3,5-ДИЗАМЕЩЕННОГО-3H-ИМИДАЗО[4,5-b]ПИРИДИНА И 3,5-ДИЗАМЕЩЕННОГО-3H-[1,2,3]ТРИАЗОЛО[4,5-b]ПИРИДИНА КАК МОДУЛЯТОРЫ ПРОТЕИНКИНАЗ
CN102274189A (zh) * 2011-07-21 2011-12-14 瑞普(天津)生物药业有限公司 一种含有癸氧喹酯的干混悬剂组方及其制备方法
TW201322979A (zh) 2011-10-18 2013-06-16 Raqualia Pharma Inc 醫藥組成物
TWI594986B (zh) 2011-12-28 2017-08-11 Taiho Pharmaceutical Co Ltd Antineoplastic agent effect enhancer
RU2494470C1 (ru) 2012-04-04 2013-09-27 Общество с ограниченной ответственностью "Саентифик Фьючер Менеджмент" (ООО "Саентифик Фьючер Менеджмент") Способ лечения фиброза легких
HRP20251029T1 (hr) 2013-07-19 2025-10-24 Boehringer Ingelheim Vetmedica Gmbh Konzervirani eterificirani derivati ciklodekstrina koji sadrže tekući vodeni farmaceutski pripravak
US9149471B2 (en) 2013-09-30 2015-10-06 National University Corporation Tokyo University Of Agriculture And Technology Therapeutic agent for osteoporosis
EP3572430A3 (en) 2014-03-05 2020-02-12 Bristol-Myers Squibb Company Treatment of renal cancer using a combination of an anti-pd-1 antibody and another anti-cancer agent
AU2015358384B2 (en) 2014-12-03 2021-03-04 Auckland Uniservices, Ltd. Kinase inhibitor prodrug for the treatment of cancer
JP2016196411A (ja) 2015-03-04 2016-11-24 エーザイ・アール・アンド・ディー・マネジメント株式会社 腫瘍治療剤
WO2016140717A1 (en) 2015-03-04 2016-09-09 Merck Sharp & Dohme Corp. Combination of a pd-1 antagonist and a vegfr/fgfr/ret tyrosine kinase inhibitor for treating cancer
WO2016175305A1 (ja) * 2015-04-30 2016-11-03 大鵬薬品工業株式会社 アシルチオウレア化合物のメシル酸塩及びその結晶並びにそれらの製造方法
CA2990791A1 (en) 2015-06-25 2016-12-29 Taiho Pharmaceutical Co., Ltd. Therapeutic agent for fibrosis
JP6804832B2 (ja) 2015-07-21 2020-12-23 東芝ライフスタイル株式会社 冷蔵庫
CN106551911A (zh) * 2015-09-21 2017-04-05 天津市汉康医药生物技术有限公司 一种稳定的乐伐替尼药物组合物及其制备方法
EP3583943B1 (en) 2017-02-15 2024-09-18 Taiho Pharmaceutical Co., Ltd. Pharmaceutical composition

Also Published As

Publication number Publication date
KR20190113831A (ko) 2019-10-08
AU2018222163B2 (en) 2021-01-28
TW201836608A (zh) 2018-10-16
RU2019125612A (ru) 2021-03-16
CN117137915A (zh) 2023-12-01
MX2019009717A (es) 2019-10-02
EP3583943A4 (en) 2020-12-30
DK3583943T3 (da) 2024-10-14
EP3583943B1 (en) 2024-09-18
KR102323255B1 (ko) 2021-11-08
US11110062B2 (en) 2021-09-07
CN110312511B (zh) 2023-10-27
JP6771594B2 (ja) 2020-10-21
MX383728B (es) 2025-03-14
CA3053739A1 (en) 2018-08-23
HUE068810T2 (hu) 2025-01-28
CA3053739C (en) 2023-02-14
RU2019125612A3 (pl) 2021-03-16
AU2018222163C1 (en) 2021-08-12
US12144892B2 (en) 2024-11-19
PT3583943T (pt) 2024-10-15
KR20210135354A (ko) 2021-11-12
MY194278A (en) 2022-11-25
EP3583943A1 (en) 2019-12-25
AU2018222163A1 (en) 2019-09-05
CN110312511A (zh) 2019-10-08
US20210308056A1 (en) 2021-10-07
BR112019016764A2 (pt) 2020-03-31
TWI702951B (zh) 2020-09-01
US20200060973A1 (en) 2020-02-27
FI3583943T3 (fi) 2024-10-29
PH12019501873A1 (en) 2020-06-15
JPWO2018151177A1 (ja) 2019-11-07
MA47516A (fr) 2021-03-31
ES2991062T3 (es) 2024-12-02
WO2018151177A1 (ja) 2018-08-23
MX2021007061A (es) 2022-10-07
SG11201907433TA (en) 2019-09-27

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