PL337606A1 - Derivatives of erythromycin 9-oxime - Google Patents

Derivatives of erythromycin 9-oxime

Info

Publication number: PL337606A1
Authority: PL; Poland
Prior art keywords: erythromycin; oxime; derivatives
Prior art date: 1997-06-11

Application number

PL98337606A

Other languages

English (en)

Inventor

Young-Jin Wu

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-11

Filing date

1998-05-15

Publication date

2000-08-28

1998-05-15 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2000-08-28 Publication of PL337606A1 publication Critical patent/PL337606A1/xx

Links

KYTWXIARANQMCA-PGYIPVOXSA-N (3r,4s,5s,6r,7r,9r,10z,11s,12r,13s,14r)-6-[(2s,3r,4s,6r)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-10-hydroxyimino-4-[(2r,4r,5s,6s)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradec Chemical class O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=N\O)/[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 KYTWXIARANQMCA-PGYIPVOXSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Molecular Biology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Tropical Medicine & Parasitology (AREA)
Epidemiology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

PL98337606A 1997-06-11 1998-05-15 Derivatives of erythromycin 9-oxime PL337606A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US4934997P	1997-06-11	1997-06-11
PCT/IB1998/000741 WO1998056800A1 (fr)	1997-06-11	1998-05-15	Derives de 9-oxime erythromycine

Publications (1)

Publication Number	Publication Date
PL337606A1 true PL337606A1 (en)	2000-08-28

Family

ID=21959341

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL98337606A PL337606A1 (en)	1997-06-11	1998-05-15	Derivatives of erythromycin 9-oxime

Country Status (31)

Country	Link
EP (1)	EP0988308A1 (fr)
JP (1)	JP2000513026A (fr)
KR (1)	KR20010013660A (fr)
CN (1)	CN1259135A (fr)
AP (1)	AP9801253A0 (fr)
AR (1)	AR012244A1 (fr)
AU (1)	AU7226798A (fr)
BG (1)	BG103947A (fr)
BR (1)	BR9810021A (fr)
CA (1)	CA2293335A1 (fr)
CO (1)	CO4940506A1 (fr)
CZ (1)	CZ9904388A3 (fr)
EA (1)	EA199901016A1 (fr)
GT (1)	GT199800074A (fr)
HN (1)	HN1998000073A (fr)
HR (1)	HRP980316A2 (fr)
HU (1)	HUP0002252A3 (fr)
ID (1)	ID24529A (fr)
IL (1)	IL132767A0 (fr)
IS (1)	IS5251A (fr)
MA (1)	MA26505A1 (fr)
NO (1)	NO996108L (fr)
OA (1)	OA11225A (fr)
PA (1)	PA8451801A1 (fr)
PE (1)	PE79899A1 (fr)
PL (1)	PL337606A1 (fr)
TN (1)	TNSN98083A1 (fr)
TR (1)	TR199902995T2 (fr)
TW (1)	TW448174B (fr)
WO (1)	WO1998056800A1 (fr)
ZA (1)	ZA985018B (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HN1998000159A (es) *	1997-10-29	1999-02-09	Monsanto Co	Derivados de 9- amino - 3 ceto eritromicina
ES2243066T3 (es)	1998-09-22	2005-11-16	Pfizer Products Inc.	Antibioticos de carbamato y carbazato cetolida.
FR2786188B1 (fr) *	1998-11-24	2002-10-31	Hoechst Marion Roussel Inc	Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
US6258785B1 (en)	1998-12-02	2001-07-10	Pfizer Inc.	Crystalline 9-E-(O-methyl)oxime of 11, 12-dideoxy-3-de(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribohexopyranosyloxy)-6-O-methyl-12,11-(iminocarbonyl-(2-(3-(4-(3-pyridinyl)1H-imadazol-1-yl)propyl)hydrazono))-3-oxoerythromycin
EP1298138B1 (fr) *	1998-12-10	2006-11-02	Pfizer Products Inc.	Dérivés anitiobiotiques de Carbamate et de Carbazate Kètolides
US6284732B1 (en) *	1998-12-18	2001-09-04	Bio-Rad Laboratories, Inc.	Peptides and peptide analogues designed from HFE protein and their uses in the treatment of iron overload diseases
KR20020007374A (ko) *	1999-04-16	2002-01-26	추후제출	매크롤라이드 항감염제
IL145739A0 (en)	1999-05-24	2002-07-25	Pfizer Prod Inc	13-methyl-erythromycin derivatives
ES2208334T3 (es) *	1999-06-07	2004-06-16	Abbott Laboratories	Derivados cetolida de 6-0 carbamato.
ID27331A (id) *	1999-09-29	2001-03-29	Pfizer Prod Inc	Pembuatan antibiotik-antibiotik ketolida karbamat
EP1114826A3 (fr) *	1999-12-29	2001-10-31	Pfizer Products Inc.	Macrolides antibactériennes et prokinétiques
EP1439186A3 (fr) *	1999-12-29	2004-11-03	Pfizer Products Inc.	Intermédiaires pour macrolides antibactérielles et procinétiques
US6946446B2 (en)	2000-02-24	2005-09-20	Abbott Laboratories	Anti-infective agents useful against multidrug-resistant strains of bacteria
US6403776B1 (en)	2000-07-05	2002-06-11	Pfizer Inc.	Synthesis of carbamate ketolide antibiotics
WO2003090761A1 (fr) *	2002-04-25	2003-11-06	Abbott Laboratories	Antibacteriens 9-oxime macrolide
TW200420573A (en)	2002-09-26	2004-10-16	Rib X Pharmaceuticals Inc	Bifunctional heterocyclic compounds and methods of making and using same
EP3738591A3 (fr)	2003-03-10	2021-03-24	Merck Sharp & Dohme Corp.	Nouveaux agents antibactériens
US8202843B2 (en)	2004-02-27	2012-06-19	Rib-X Pharmaceuticals, Inc.	Macrocyclic compounds and methods of making and using the same
AU2008316830B2 (en)	2007-10-25	2016-03-17	Cempra Pharmaceuticals, Inc.	Process for the preparation of macrolide antibacterial agents
US9072759B2 (en)	2008-10-24	2015-07-07	Cempra Pharmaceuticals, Inc.	Biodefenses using triazole-containing macrolides
US9937194B1 (en)	2009-06-12	2018-04-10	Cempra Pharmaceuticals, Inc.	Compounds and methods for treating inflammatory diseases
ES2608285T3 (es)	2009-09-10	2017-04-07	Cempra Pharmaceuticals, Inc.	Procedimientos para el tratamiento de paludismo, tuberculosis y enfermedades por MAC
CN102146085B (zh) *	2010-02-09	2014-03-26	北京理工大学	一种9-肟醚酮内酯衍生物、制备方法及其药物组合物
ES2564097T3 (es)	2010-03-22	2016-03-17	Cempra Pharmaceuticals, Inc.	Formas cristalinas de un macrólido, y usos de las mismas
ES2636948T3 (es)	2010-05-20	2017-10-10	Cempra Pharmaceuticals, Inc.	Procesos para preparar macrólidos y cetólidos e intermediarios para los mismos
WO2012034058A1 (fr)	2010-09-10	2012-03-15	Cempra Pharmaceuticals, Inc.	Fluorocétolides formant des liaisons hydrogène pour traiter les maladies
IN2014DN08939A (fr)	2012-03-27	2015-05-22	Cempra Pharmaceuticals Inc
CN105163785A (zh)	2013-03-14	2015-12-16	森普拉制药公司	用于治疗呼吸道疾病的方法及其制剂
RU2015138797A (ru)	2013-03-15	2017-04-24	Семпра Фармасьютикалс, Инк.	Конвергентные способы получения макролидных антибактериальных агентов

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL114589A (en) *	1990-11-21	1999-12-22	Roussel Uclaf	Intermediates for the preparation of erythromycin derivatives
US5527780A (en) *	1992-11-05	1996-06-18	Roussel Uclaf	Erythromycin derivatives
FR2718450B1 (fr) *	1994-04-08	1997-01-10	Roussel Uclaf	Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

1998
- 1998-05-15 TR TR1999/02995T patent/TR199902995T2/xx unknown
- 1998-05-15 ID IDW991570A patent/ID24529A/id unknown
- 1998-05-15 KR KR1019997011672A patent/KR20010013660A/ko not_active Ceased
- 1998-05-15 CZ CZ19994388A patent/CZ9904388A3/cs unknown
- 1998-05-15 CA CA002293335A patent/CA2293335A1/fr not_active Abandoned
- 1998-05-15 EP EP98919394A patent/EP0988308A1/fr not_active Withdrawn
- 1998-05-15 PL PL98337606A patent/PL337606A1/xx unknown
- 1998-05-15 HU HU0002252A patent/HUP0002252A3/hu unknown
- 1998-05-15 AU AU72267/98A patent/AU7226798A/en not_active Abandoned
- 1998-05-15 IL IL13276798A patent/IL132767A0/xx unknown
- 1998-05-15 EA EA199901016A patent/EA199901016A1/ru unknown
- 1998-05-15 JP JP11501928A patent/JP2000513026A/ja active Pending
- 1998-05-15 WO PCT/IB1998/000741 patent/WO1998056800A1/fr not_active Ceased
- 1998-05-15 CN CN98805848A patent/CN1259135A/zh active Pending
- 1998-05-15 BR BR9810021-1A patent/BR9810021A/pt not_active IP Right Cessation
- 1998-05-19 HN HN1998000073A patent/HN1998000073A/es unknown
- 1998-05-21 PA PA19988451801A patent/PA8451801A1/es unknown
- 1998-06-04 AP APAP/P/1998/001253A patent/AP9801253A0/en unknown
- 1998-06-05 GT GT199800074A patent/GT199800074A/es unknown
- 1998-06-08 TW TW087109086A patent/TW448174B/zh active
- 1998-06-08 PE PE1998000470A patent/PE79899A1/es not_active Application Discontinuation
- 1998-06-09 AR ARP980102703A patent/AR012244A1/es unknown
- 1998-06-10 TN TNTNSN98083A patent/TNSN98083A1/fr unknown
- 1998-06-10 MA MA25105A patent/MA26505A1/fr unknown
- 1998-06-10 ZA ZA9805018A patent/ZA985018B/xx unknown
- 1998-06-11 CO CO98033538A patent/CO4940506A1/es unknown
- 1998-06-11 HR HR60/049,349A patent/HRP980316A2/hr not_active Application Discontinuation
1999
- 1999-11-16 IS IS5251A patent/IS5251A/is unknown
- 1999-12-03 OA OA9900269A patent/OA11225A/en unknown
- 1999-12-03 BG BG103947A patent/BG103947A/xx unknown
- 1999-12-10 NO NO996108A patent/NO996108L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO996108L (no)	2000-02-10
NO996108D0 (no)	1999-12-10
EA199901016A1 (ru)	2000-06-26
BR9810021A (pt)	2000-09-19
OA11225A (en)	2003-07-17
HUP0002252A2 (hu)	2000-12-28
ID24529A (id)	2000-07-20
GT199800074A (es)	1999-11-27
WO1998056800A1 (fr)	1998-12-17
CZ9904388A3 (cs)	2002-10-16
TNSN98083A1 (fr)	2005-03-15
IS5251A (is)	1999-11-16
PA8451801A1 (es)	2000-05-24
TR199902995T2 (xx)	2000-02-21
BG103947A (en)	2000-07-31
KR20010013660A (ko)	2001-02-26
MA26505A1 (fr)	2004-12-20
CO4940506A1 (es)	2000-07-24
PE79899A1 (es)	1999-08-25
HUP0002252A3 (en)	2002-01-28
ZA985018B (en)	1999-12-10
AU7226798A (en)	1998-12-30
HRP980316A2 (en)	1999-04-30
CA2293335A1 (fr)	1998-12-17
HN1998000073A (es)	1999-01-08
AR012244A1 (es)	2000-09-27
AP9801253A0 (en)	1999-12-04
JP2000513026A (ja)	2000-10-03
CN1259135A (zh)	2000-07-05
EP0988308A1 (fr)	2000-03-29
IL132767A0 (en)	2001-03-19
TW448174B (en)	2001-08-01

Publication	Publication Date	Title
PL337606A1 (en)	2000-08-28	Derivatives of erythromycin 9-oxime
IL130328A0 (en)	2000-06-01	Tricyclic erythromycin derivatives
PL341647A1 (en)	2001-04-23	Novel derivatives of erythromycin
AU9277698A (en)	1999-05-17	9-amino-3-keto erythromycin derivatives
PL348333A1 (en)	2002-05-20	Macrolides
IL137024A0 (en)	2001-06-14	Novel macrolides
PL348114A1 (en)	2002-05-06	Novel macrolide antibiotics
PL340290A1 (en)	2001-01-29	2-halogeno-6-0-substituted derivatives of ketolide
PL339137A1 (en)	2000-12-04	6,9-bridged derivatives of erythromycin
PL340253A1 (en)	2001-01-29	6,11-bridged derivatives of erythromycin
PL324346A1 (en)	1998-05-25	Macrolides
ZA985655B (en)	1998-12-30	Crystalline macrolides
IL145256A0 (en)	2002-06-30	Erythromycin derivatives
AU8925398A (en)	1999-03-22	3-descladinose 6-o-substituded erythromycin derivatives
AU6932098A (en)	1998-12-08	Erythromycin derivatives
IL115312A0 (en)	1995-12-31	Antibiotic macrolides
AU1504899A (en)	1999-06-28	Erythromycin derivatives
PL337066A1 (en)	2000-07-31	Polycyclic derivatives of erythromycin
GB9700702D0 (en)	1997-03-05	Erythromycin derivatives
ZA951845B (en)	1996-03-15	Acid-stabile erythromycin derivatives
HK1031384A (en)	2001-06-15	3-descladinose 6-o-substituted erythromycin derivatives
ZA989845B (en)	1999-04-29	2-halo-6-O-substituted ketolide derivatives
SI1027362T1 (sl)	2005-12-31	2-halo-6-O-substituirani derivati ketolidov
AU3634397A (en)	1998-02-10	Erythromycin derivatives
PL319678A1 (en)	1998-10-26	Method of biosynthesising erythromycin c