ZA985018B - 9-oxime erythromycin derivatives. - Google Patents

9-oxime erythromycin derivatives.

Info

Publication number: ZA985018B
Authority: ZA; South Africa
Prior art keywords: erythromycin derivatives; oxime erythromycin; oxime; derivatives; erythromycin
Prior art date: 1997-06-11

Application number

ZA9805018A

Other languages

English (en)

Inventor

Yong-Jin Wu

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-11

Filing date

1998-06-10

Publication date

1999-12-10

1998-06-10 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

1999-12-10 Publication of ZA985018B publication Critical patent/ZA985018B/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Molecular Biology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Genetics & Genomics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Tropical Medicine & Parasitology (AREA)
Epidemiology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

ZA9805018A 1997-06-11 1998-06-10 9-oxime erythromycin derivatives. ZA985018B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US4934997P	1997-06-11	1997-06-11

Publications (1)

Publication Number	Publication Date
ZA985018B true ZA985018B (en)	1999-12-10

Family

ID=21959341

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9805018A ZA985018B (en)	1997-06-11	1998-06-10	9-oxime erythromycin derivatives.

Country Status (31)

Country	Link
EP (1)	EP0988308A1 (xx)
JP (1)	JP2000513026A (xx)
KR (1)	KR20010013660A (xx)
CN (1)	CN1259135A (xx)
AP (1)	AP9801253A0 (xx)
AR (1)	AR012244A1 (xx)
AU (1)	AU7226798A (xx)
BG (1)	BG103947A (xx)
BR (1)	BR9810021A (xx)
CA (1)	CA2293335A1 (xx)
CO (1)	CO4940506A1 (xx)
CZ (1)	CZ9904388A3 (xx)
EA (1)	EA199901016A1 (xx)
GT (1)	GT199800074A (xx)
HN (1)	HN1998000073A (xx)
HR (1)	HRP980316A2 (xx)
HU (1)	HUP0002252A3 (xx)
ID (1)	ID24529A (xx)
IL (1)	IL132767A0 (xx)
IS (1)	IS5251A (xx)
MA (1)	MA26505A1 (xx)
NO (1)	NO996108L (xx)
OA (1)	OA11225A (xx)
PA (1)	PA8451801A1 (xx)
PE (1)	PE79899A1 (xx)
PL (1)	PL337606A1 (xx)
TN (1)	TNSN98083A1 (xx)
TR (1)	TR199902995T2 (xx)
TW (1)	TW448174B (xx)
WO (1)	WO1998056800A1 (xx)
ZA (1)	ZA985018B (xx)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HN1998000159A (es) *	1997-10-29	1999-02-09	Monsanto Co	Derivados de 9- amino - 3 ceto eritromicina
ES2243066T3 (es) *	1998-09-22	2005-11-16	Pfizer Products Inc.	Antibioticos de carbamato y carbazato cetolida.
FR2786188B1 (fr) *	1998-11-24	2002-10-31	Hoechst Marion Roussel Inc	Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
US6258785B1 (en)	1998-12-02	2001-07-10	Pfizer Inc.	Crystalline 9-E-(O-methyl)oxime of 11, 12-dideoxy-3-de(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribohexopyranosyloxy)-6-O-methyl-12,11-(iminocarbonyl-(2-(3-(4-(3-pyridinyl)1H-imadazol-1-yl)propyl)hydrazono))-3-oxoerythromycin
EP1298138B1 (en) *	1998-12-10	2006-11-02	Pfizer Products Inc.	Carbamate and Carbazate Ketolide Antibiotics
US6284732B1 (en) *	1998-12-18	2001-09-04	Bio-Rad Laboratories, Inc.	Peptides and peptide analogues designed from HFE protein and their uses in the treatment of iron overload diseases
US6395710B1 (en) *	1999-04-16	2002-05-28	Kosan Biosciences, Inc.	Macrolide antiinfective agents
KR20020016799A (ko)	1999-05-24	2002-03-06	데이비드 존 우드	13-메틸-에리트로마이신 유도체
MXPA01012661A (es) *	1999-06-07	2002-07-22	Abbott Lab	Derivados de 6-o-carbamato quetolida.
ID27331A (id) *	1999-09-29	2001-03-29	Pfizer Prod Inc	Pembuatan antibiotik-antibiotik ketolida karbamat
EP1114826A3 (en) *	1999-12-29	2001-10-31	Pfizer Products Inc.	Novel antibacterial and prokinetic macrolides
EP1439186A3 (en) *	1999-12-29	2004-11-03	Pfizer Products Inc.	Intermediates for novel antibacterial and prokinetic macrolides
US6946446B2 (en)	2000-02-24	2005-09-20	Abbott Laboratories	Anti-infective agents useful against multidrug-resistant strains of bacteria
US6403776B1 (en)	2000-07-05	2002-06-11	Pfizer Inc.	Synthesis of carbamate ketolide antibiotics
WO2003090761A1 (en) *	2002-04-25	2003-11-06	Abbott Laboratories	9-oxime macrolide antibacterials
AR043050A1 (es)	2002-09-26	2005-07-13	Rib X Pharmaceuticals Inc	Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
CA2529817C (en)	2003-03-10	2013-02-12	Optimer Pharmaceuticals, Inc.	Novel antibacterial agents
JP5383037B2 (ja)	2004-02-27	2014-01-08	リブ−エックスファーマシューティカルズ，インコーポレイテッド	大環状化合物およびそれらを製造し使用する方法
AU2008316830B2 (en)	2007-10-25	2016-03-17	Cempra Pharmaceuticals, Inc.	Process for the preparation of macrolide antibacterial agents
WO2010048600A1 (en)	2008-10-24	2010-04-29	Cempra Pharmaceuticals, Inc.	Methods for treating resistant diseases using triazole containing macrolides
US9937194B1 (en)	2009-06-12	2018-04-10	Cempra Pharmaceuticals, Inc.	Compounds and methods for treating inflammatory diseases
US9480679B2 (en)	2009-09-10	2016-11-01	Cempra Pharmaceuticals, Inc.	Methods for treating malaria, tuberculosis and MAC diseases
CN102146085B (zh) *	2010-02-09	2014-03-26	北京理工大学	一种9-肟醚酮内酯衍生物、制备方法及其药物组合物
HRP20160168T1 (hr)	2010-03-22	2016-03-25	Cempra Pharmaceuticals Inc	Kristalne forme makrolida i njihova uporaba
EP2571506B1 (en)	2010-05-20	2017-05-10	Cempra Pharmaceuticals, Inc.	Processes for preparing macrolides and ketolides and intermediates therefor
KR20130120458A (ko)	2010-09-10	2013-11-04	셈프라 파마슈티컬스, 인크.	질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
WO2013148891A1 (en)	2012-03-27	2013-10-03	Cempra Pharmaceuticals, Inc.	Parenteral formulations for administering macrolide antibiotics
EP2968801B1 (en)	2013-03-14	2018-09-26	Cempra Pharmaceuticals, Inc.	Methods for treating respiratory diseases and formulations therefor
MX356772B (es)	2013-03-15	2018-06-13	Cempra Pharmaceuticals Inc	Procesos convergentes para la preparacion de agentes antibacterianos macrolidos.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL114589A (en) *	1990-11-21	1999-12-22	Roussel Uclaf	Intermediates for the preparation of erythromycin derivatives
US5527780A (en) *	1992-11-05	1996-06-18	Roussel Uclaf	Erythromycin derivatives
FR2718450B1 (fr) *	1994-04-08	1997-01-10	Roussel Uclaf	Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

1998
- 1998-05-15 PL PL98337606A patent/PL337606A1/xx unknown
- 1998-05-15 KR KR1019997011672A patent/KR20010013660A/ko not_active Ceased
- 1998-05-15 BR BR9810021-1A patent/BR9810021A/pt not_active IP Right Cessation
- 1998-05-15 EP EP98919394A patent/EP0988308A1/en not_active Withdrawn
- 1998-05-15 IL IL13276798A patent/IL132767A0/xx unknown
- 1998-05-15 AU AU72267/98A patent/AU7226798A/en not_active Abandoned
- 1998-05-15 EA EA199901016A patent/EA199901016A1/ru unknown
- 1998-05-15 JP JP11501928A patent/JP2000513026A/ja active Pending
- 1998-05-15 WO PCT/IB1998/000741 patent/WO1998056800A1/en not_active Ceased
- 1998-05-15 HU HU0002252A patent/HUP0002252A3/hu unknown
- 1998-05-15 CA CA002293335A patent/CA2293335A1/en not_active Abandoned
- 1998-05-15 CZ CZ19994388A patent/CZ9904388A3/cs unknown
- 1998-05-15 TR TR1999/02995T patent/TR199902995T2/xx unknown
- 1998-05-15 ID IDW991570A patent/ID24529A/id unknown
- 1998-05-15 CN CN98805848A patent/CN1259135A/zh active Pending
- 1998-05-19 HN HN1998000073A patent/HN1998000073A/es unknown
- 1998-05-21 PA PA19988451801A patent/PA8451801A1/es unknown
- 1998-06-04 AP APAP/P/1998/001253A patent/AP9801253A0/en unknown
- 1998-06-05 GT GT199800074A patent/GT199800074A/es unknown
- 1998-06-08 TW TW087109086A patent/TW448174B/zh active
- 1998-06-08 PE PE1998000470A patent/PE79899A1/es not_active Application Discontinuation
- 1998-06-09 AR ARP980102703A patent/AR012244A1/es unknown
- 1998-06-10 ZA ZA9805018A patent/ZA985018B/xx unknown
- 1998-06-10 MA MA25105A patent/MA26505A1/fr unknown
- 1998-06-10 TN TNTNSN98083A patent/TNSN98083A1/fr unknown
- 1998-06-11 HR HR60/049,349A patent/HRP980316A2/hr not_active Application Discontinuation
- 1998-06-11 CO CO98033538A patent/CO4940506A1/es unknown
1999
- 1999-11-16 IS IS5251A patent/IS5251A/is unknown
- 1999-12-03 BG BG103947A patent/BG103947A/xx unknown
- 1999-12-03 OA OA9900269A patent/OA11225A/en unknown
- 1999-12-10 NO NO996108A patent/NO996108L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
PL337606A1 (en)	2000-08-28
BR9810021A (pt)	2000-09-19
CA2293335A1 (en)	1998-12-17
PA8451801A1 (es)	2000-05-24
PE79899A1 (es)	1999-08-25
NO996108D0 (no)	1999-12-10
IS5251A (is)	1999-11-16
JP2000513026A (ja)	2000-10-03
HUP0002252A2 (hu)	2000-12-28
BG103947A (en)	2000-07-31
IL132767A0 (en)	2001-03-19
ID24529A (id)	2000-07-20
AU7226798A (en)	1998-12-30
WO1998056800A1 (en)	1998-12-17
EP0988308A1 (en)	2000-03-29
TW448174B (en)	2001-08-01
AR012244A1 (es)	2000-09-27
AP9801253A0 (en)	1999-12-04
MA26505A1 (fr)	2004-12-20
CN1259135A (zh)	2000-07-05
HRP980316A2 (en)	1999-04-30
GT199800074A (es)	1999-11-27
TNSN98083A1 (fr)	2005-03-15
HUP0002252A3 (en)	2002-01-28
CZ9904388A3 (cs)	2002-10-16
CO4940506A1 (es)	2000-07-24
NO996108L (no)	2000-02-10
TR199902995T2 (xx)	2000-02-21
OA11225A (en)	2003-07-17
KR20010013660A (ko)	2001-02-26
HN1998000073A (es)	1999-01-08
EA199901016A1 (ru)	2000-06-26

Publication	Publication Date	Title
ZA985018B (en)	1999-12-10	9-oxime erythromycin derivatives.
ZA9811940B (en)	2000-06-30	Novel erythromycin derivatives.
ZA9811939B (en)	2000-06-30	Novel macrolides.
PL348333A1 (en)	2002-05-20	Macrolides
AU9277698A (en)	1999-05-17	9-amino-3-keto erythromycin derivatives
ZA985016B (en)	1999-12-10	C-4"-substituted macrolide derivatives.
ZA98986B (en)	1998-08-05	3'-n-oxide,3'-N-dimethylamine, 9-oxime erythromycin A derivatives
ZA200103289B (en)	2002-08-28	Novel macrolide antibiotics.
ZA9710648B (en)	1998-06-23	Erythromycin A derivatives.
IL134220A0 (en)	2001-04-30	6,9-bridged erythromycin derivatives
IL134996A0 (en)	2001-05-20	6,11-bridged erythromycin derivatives
HUP0004282A3 (en)	2001-10-29	2-halo-6-0-substituted ketolide derivatives
ZA200107346B (en)	2002-11-27	Erythromycin derivatives.
AU8925398A (en)	1999-03-22	3-descladinose 6-o-substituded erythromycin derivatives
ZA983902B (en)	1999-11-08	Erythromycin derivatives.
AU1504899A (en)	1999-06-28	Erythromycin derivatives
ZA978546B (en)	1998-04-01	Erythromycin A derivatives.
MXPA99011001A (es)	2003-09-10	Derivados de eritromicina multiciclicos.
ZA989848B (en)	1999-04-29	6,11-bridged erythromycin derivatives
SI1027361T1 (en)	2004-02-29	6,11-bridged erythromycin derivatives
SI1015467T1 (en)	2004-06-30	6,9-bridged erythromycin derivatives
GB9700702D0 (en)	1997-03-05	Erythromycin derivatives
HK1031384A (en)	2001-06-15	3-descladinose 6-o-substituted erythromycin derivatives
SI0966477T1 (en)	2004-02-29	3'-n-oxide, 3'-n-dimethylamine, 9-oxime erythromycin a derivatives
ZA965692B (en)	1998-01-05	Macrolides.