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PL2764008T3 - Sposób wytwarzania estetrolu - Google Patents

Sposób wytwarzania estetrolu

Info

Publication number
PL2764008T3
PL2764008T3 PL12778664T PL12778664T PL2764008T3 PL 2764008 T3 PL2764008 T3 PL 2764008T3 PL 12778664 T PL12778664 T PL 12778664T PL 12778664 T PL12778664 T PL 12778664T PL 2764008 T3 PL2764008 T3 PL 2764008T3
Authority
PL
Poland
Prior art keywords
estetrol
production
Prior art date
Application number
PL12778664T
Other languages
English (en)
Inventor
Jean-Claude Pascal
Original Assignee
Estetra S.P.R.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48043195&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2764008(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Estetra S.P.R.L. filed Critical Estetra S.P.R.L.
Publication of PL2764008T3 publication Critical patent/PL2764008T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0066Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL12778664T 2011-10-07 2012-10-05 Sposób wytwarzania estetrolu PL2764008T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161544591P 2011-10-07 2011-10-07
EP11184278 2011-10-07
EP12778664.8A EP2764008B1 (en) 2011-10-07 2012-10-05 Process for the production of estetrol

Publications (1)

Publication Number Publication Date
PL2764008T3 true PL2764008T3 (pl) 2017-04-28

Family

ID=48043195

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12778664T PL2764008T3 (pl) 2011-10-07 2012-10-05 Sposób wytwarzania estetrolu

Country Status (26)

Country Link
US (1) US8987484B2 (pl)
EP (1) EP2764008B1 (pl)
JP (1) JP6196625B2 (pl)
KR (1) KR102007874B1 (pl)
CN (1) CN103890001B (pl)
AU (1) AU2012320423C1 (pl)
BR (1) BR112014008196B8 (pl)
CA (1) CA2847813C (pl)
CL (1) CL2014000802A1 (pl)
CY (1) CY1118674T1 (pl)
DK (1) DK2764008T3 (pl)
EA (1) EA024003B1 (pl)
ES (1) ES2593316T3 (pl)
HR (1) HRP20161282T1 (pl)
HU (1) HUE028963T2 (pl)
IN (1) IN2014MN00841A (pl)
LT (1) LT2764008T (pl)
ME (1) ME02527B (pl)
MX (1) MX348917B (pl)
PL (1) PL2764008T3 (pl)
PT (1) PT2764008T (pl)
RS (1) RS55231B1 (pl)
SG (1) SG11201401282PA (pl)
SI (1) SI2764008T1 (pl)
SM (1) SMT201600375B (pl)
WO (1) WO2013050553A1 (pl)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2714712T3 (pl) 2011-06-01 2017-05-31 Estetra S.P.R.L. Metoda wytwarzania półproduktów estetrolu
CN107266514A (zh) 2011-06-01 2017-10-20 埃斯特拉私人有限责任公司 用于产生雌四醇中间体的方法
EP2383279A1 (en) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol
WO2013034780A2 (en) * 2012-12-20 2013-03-14 Crystal Pharma, S.A.U. Process for the preparation of estetrol and related compounds
CA2924255C (en) * 2013-09-18 2022-11-22 Crystal Pharma, S.A.U. Process for the preparation of estetrol
UA123098C2 (uk) 2015-06-18 2021-02-17 Естетра Спрл Диспергована у порожнині рота одиниця дозування, що містить естетрольний компонент
CA2988485A1 (en) 2015-06-18 2016-12-22 Mithra Pharmaceuticals S.A. Orodispersible tablet containing estetrol
PE20180522A1 (es) 2015-06-18 2018-03-14 Mithra Pharmaceuticals S A Unidad de dosificacion orodispersable que contiene un componente estetrol
EP3310346B1 (en) * 2015-06-18 2021-03-24 Estetra SPRL Orodispersible tablet containing estetrol
KR102712911B1 (ko) 2016-08-05 2024-10-04 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 월경통 및 생리통의 관리방법
JOP20200260A1 (ar) 2018-04-19 2019-10-19 Estetra Sprl مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
EP3647413A1 (en) * 2018-10-31 2020-05-06 Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas O.A., M.P. (CIEMAT) Improvements for performing and facilitating the recovery after hematopoietic stem cell transplantation
HU231240B1 (hu) 2019-09-03 2022-04-28 Richter Gedeon Nyrt. Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására
IT201900021879A1 (it) 2019-11-22 2021-05-22 Ind Chimica Srl PROCESSO PER LA PREPARAZIONE DI (15α,16α,17β)-ESTRA-1,3,5(10)-TRIENE-3,15,16,17-TETROLO (ESTETROLO) ED INTERMEDI DI DETTO PROCESSO
IT201900017414A1 (it) 2019-09-27 2021-03-27 Ind Chimica Srl Processo per la preparazione di (15α,16α,17β)-estra-1,3,5(10)-triene-3,15,16,17-tetrolo (Estetrolo) ed intermedi di detto processo
ES2915058B2 (es) 2019-09-27 2024-06-21 Ind Chimica Srl Proceso para preparar (15alfa,16alfa,17beta)-estra-1,3,5(10)-trieno-3,15,16,17-tetrol (Estetrol) e intermedios de dicho proceso
TWI893101B (zh) 2020-04-16 2025-08-11 比利時商埃斯特拉有限責任公司 具有降低之副作用之避孕組成物
IT202100019631A1 (it) 2021-07-23 2023-01-23 Newchem S P A Metodo per produrre estetrolo e i suoi intermedi
WO2023021026A1 (en) 2021-08-17 2023-02-23 Aspen Oss B.V. A synthetic pathway to estra-1,3,5(10)-triene-3,15a,16a,17b-tetrol
US20240391947A1 (en) 2021-10-01 2024-11-28 Industriale Chimica S.R.L. PROCESS FOR PREPARING (15alpha,16alpha,17beta)-ESTRA-1,3,5(10)-TRIENE-3,15,16,17-TETROL (ESTETROL) AND ESTETROL MONOHYDRATE
ES3036185A2 (es) 2023-02-02 2025-09-15 Ind Chimica Srl PROCESO DE PREPARACION DE MONOHIDRATO DE (15alfa,16alfa,17beta)-ESTRA-1,3,5(10)-TRIENO-3,15,16,17-TETROL (ESTETROL)
TW202517240A (zh) * 2023-08-30 2025-05-01 比利時商艾斯特答有限責任公司 雌四醇中間物之製造方法
HUP2400151A1 (hu) 2024-02-28 2025-09-28 Richter Gedeon Nyrt Ösztetrol-monohidrát kristályosítási eljárás
CL2025000553A1 (es) 2024-02-28 2025-08-29 Estetra Srl Forma polimórfica de estetrol y producción de la misma

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW548277B (en) * 1999-07-16 2003-08-21 Akzo Nobel Nv Orally active androgens
IL149424A (en) * 1999-12-02 2007-05-15 Organon Nv Androgens are converted to methylene at positions 15,14
DE60332754D1 (de) 2002-11-08 2010-07-08 Pantarhei Bioscience Bv Synthese von oestetrol aus von oestron abgeleiteten steroiden
UA89964C2 (ru) * 2004-09-08 2010-03-25 Н.В. Органон 15β-ЗАМЕЩЕННЫЕ СТЕРОИДЫ, КОТОРЫЕ ИМЕЮТ СЕЛЕКТИВНУЮ ЭСТРОГЕННУЮ АКТИВНОСТЬ
PL2714712T3 (pl) 2011-06-01 2017-05-31 Estetra S.P.R.L. Metoda wytwarzania półproduktów estetrolu
CN107266514A (zh) 2011-06-01 2017-10-20 埃斯特拉私人有限责任公司 用于产生雌四醇中间体的方法
EP2383279A1 (en) * 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol

Also Published As

Publication number Publication date
DK2764008T3 (en) 2016-11-07
HRP20161282T1 (hr) 2016-11-18
MX348917B (es) 2017-07-04
RS55231B1 (sr) 2017-02-28
BR112014008196A2 (pt) 2017-04-18
BR112014008196B1 (pt) 2020-10-20
AU2012320423B2 (en) 2017-02-09
ME02527B (me) 2017-02-20
WO2013050553A1 (en) 2013-04-11
JP2014528438A (ja) 2014-10-27
EP2764008B1 (en) 2016-08-17
HK1199882A1 (zh) 2015-07-24
BR112014008196B8 (pt) 2020-12-15
SI2764008T1 (sl) 2016-10-28
MX2014003723A (es) 2014-10-13
EA024003B1 (ru) 2016-08-31
US20140243539A1 (en) 2014-08-28
AU2012320423A1 (en) 2014-03-20
AU2012320423C1 (en) 2018-01-25
CL2014000802A1 (es) 2014-11-14
US8987484B2 (en) 2015-03-24
SMT201600375B (it) 2017-01-10
IN2014MN00841A (pl) 2015-07-03
EA201490713A1 (ru) 2014-07-30
CA2847813C (en) 2018-12-11
HUE028963T2 (en) 2017-01-30
JP6196625B2 (ja) 2017-09-13
LT2764008T (lt) 2016-11-10
KR102007874B1 (ko) 2019-08-06
ES2593316T3 (es) 2016-12-07
CA2847813A1 (en) 2013-04-11
PT2764008T (pt) 2016-11-10
KR20140083994A (ko) 2014-07-04
NZ621973A (en) 2015-08-28
EP2764008A1 (en) 2014-08-13
CY1118674T1 (el) 2017-07-12
CN103890001B (zh) 2016-05-04
CN103890001A (zh) 2014-06-25
SG11201401282PA (en) 2014-05-29

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