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SI2734536T1 - Postopek za pripravo estetrola - Google Patents

Postopek za pripravo estetrola

Info

Publication number
SI2734536T1
SI2734536T1 SI201230773A SI201230773A SI2734536T1 SI 2734536 T1 SI2734536 T1 SI 2734536T1 SI 201230773 A SI201230773 A SI 201230773A SI 201230773 A SI201230773 A SI 201230773A SI 2734536 T1 SI2734536 T1 SI 2734536T1
Authority
SI
Slovenia
Prior art keywords
estetrol
preparation
Prior art date
Application number
SI201230773A
Other languages
English (en)
Inventor
Johannes Jan Platteeuw
Bennink Herman Jan Tijmen Coelingh
Franciscus Wilhelmus Petrus Damen
Vliet Michiel Christian Alexander Van
Original Assignee
Donesta Bioscience B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44582248&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2734536(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Donesta Bioscience B.V. filed Critical Donesta Bioscience B.V.
Publication of SI2734536T1 publication Critical patent/SI2734536T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
SI201230773A 2011-07-19 2012-07-18 Postopek za pripravo estetrola SI2734536T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161509168P 2011-07-19 2011-07-19
EP11174509A EP2383279A1 (en) 2011-07-19 2011-07-19 Process for the preparation of estetrol
PCT/NL2012/050514 WO2013012328A1 (en) 2011-07-19 2012-07-18 Process for the preparation of estetrol
EP12742968.6A EP2734536B1 (en) 2011-07-19 2012-07-18 Process for the preparation of estetrol

Publications (1)

Publication Number Publication Date
SI2734536T1 true SI2734536T1 (sl) 2017-01-31

Family

ID=44582248

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201230773A SI2734536T1 (sl) 2011-07-19 2012-07-18 Postopek za pripravo estetrola

Country Status (16)

Country Link
US (2) US20140235882A1 (sl)
EP (2) EP2383279A1 (sl)
CN (1) CN103781795B (sl)
CA (1) CA2842035C (sl)
CY (1) CY1118288T1 (sl)
DK (1) DK2734536T3 (sl)
ES (1) ES2602227T3 (sl)
HR (1) HRP20161467T1 (sl)
HU (1) HUE029783T2 (sl)
LT (1) LT2734536T (sl)
PL (1) PL2734536T3 (sl)
PT (1) PT2734536T (sl)
RS (1) RS55384B1 (sl)
SI (1) SI2734536T1 (sl)
SM (2) SMT201600464T1 (sl)
WO (1) WO2013012328A1 (sl)

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* Cited by examiner, † Cited by third party
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EP2714712B1 (en) 2011-06-01 2016-08-24 Estetra S.P.R.L. Process for the production of estetrol intermediates
JP6425540B2 (ja) * 2011-06-01 2018-11-21 エステトラ エス．ペ．エール．エル． エステトロール中間体を製造するための方法
EP2383279A1 (en) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol
SI2764008T1 (sl) * 2011-10-07 2016-10-28 Estetra S.P.R.L. Postopek za pripravo estetrola
WO2013034780A2 (en) 2012-12-20 2013-03-14 Crystal Pharma, S.A.U. Process for the preparation of estetrol and related compounds
JP6254289B2 (ja) * 2013-09-18 2017-12-27 クリスタル ファルマ、エセ、ア、ウＣｒｙｓｔａｌ Ｐｈａｒｍａ，Ｓ．Ａ．Ｕ． エステトロールの製造プロセス
NZ737948A (en) 2015-06-18 2023-03-31 Estetra Sprl Orodispersible dosage unit containing an estetrol component
LT3310345T (lt) 2015-06-18 2021-06-25 Estetra Sprl Burnoje disperguojama tabletė, turinti estetrolio
KR102662025B1 (ko) 2015-06-18 2024-05-02 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 에스테트롤 성분을 함유하는 구강분해성 투여 단위
HUE054551T2 (hu) 2015-06-18 2021-09-28 Estetra Sprl Ösztetrolt tartalmazó, szájban diszpergálódó tabletta
CA3178291A1 (en) 2016-08-05 2018-04-12 Estetra Srl Method for the management of dysmenorrhea and menstrual pain
JOP20200260A1 (ar) 2018-04-19 2019-10-19 Estetra Sprl مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
HU231240B1 (hu) 2019-09-03 2022-04-28 Richter Gedeon Nyrt. Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására
UY38895A (es) * 2019-09-27 2021-04-30 Ind Chimica Srl PROCESO PARA PREPARAR (15a,16a,17ß)-ESTRA-1,3,5(10)-TRIENO-3,15,16,17-TETROL (ESTETROL) E INTERMEDIOS DE DICHO PROCESO
TWI893101B (zh) 2020-04-16 2025-08-11 比利時商埃斯特拉有限責任公司 具有降低之副作用之避孕組成物
US20220406595A1 (en) * 2021-06-22 2022-12-22 Applied Materials, Inc. Novel oxidants and strained-ring precursors
IT202100019631A1 (it) 2021-07-23 2023-01-23 Newchem S P A Metodo per produrre estetrolo e i suoi intermedi
WO2023021026A1 (en) 2021-08-17 2023-02-23 Aspen Oss B.V. A synthetic pathway to estra-1,3,5(10)-triene-3,15a,16a,17b-tetrol
HUP2400151A1 (hu) 2024-02-28 2025-09-28 Richter Gedeon Nyrt Ösztetrol-monohidrát kristályosítási eljárás

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Also Published As

Publication number Publication date
SMT201600464T1 (it) 2017-03-08
HUE029783T2 (en) 2017-04-28
PT2734536T (pt) 2017-01-02
CA2842035A1 (en) 2013-01-24
DK2734536T3 (en) 2016-12-12
CN103781795A (zh) 2014-05-07
ES2602227T3 (es) 2017-02-20
CN103781795B (zh) 2016-08-17
LT2734536T (lt) 2016-12-27
CY1118288T1 (el) 2017-06-28
HRP20161467T1 (hr) 2017-01-27
WO2013012328A1 (en) 2013-01-24
RS55384B1 (sr) 2017-03-31
SMT201600464B (it) 2017-03-08
US20140235882A1 (en) 2014-08-21
EP2383279A1 (en) 2011-11-02
EP2734536A1 (en) 2014-05-28
US10844088B2 (en) 2020-11-24
CA2842035C (en) 2020-06-23
PL2734536T3 (pl) 2017-03-31
EP2734536B1 (en) 2016-09-28
US20170369521A1 (en) 2017-12-28

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