PE32899A1 - Nuevas preparaciones medicamentosas acuosas para la produccion de aerosoles libres de gas propulsor - Google Patents
Nuevas preparaciones medicamentosas acuosas para la produccion de aerosoles libres de gas propulsorInfo
- Publication number
- PE32899A1 PE32899A1 PE1997001120A PE00112097A PE32899A1 PE 32899 A1 PE32899 A1 PE 32899A1 PE 1997001120 A PE1997001120 A PE 1997001120A PE 00112097 A PE00112097 A PE 00112097A PE 32899 A1 PE32899 A1 PE 32899A1
- Authority
- PE
- Peru
- Prior art keywords
- production
- medicine preparations
- new aqueous
- aqueous medicine
- gas propeller
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000007921 spray Substances 0.000 title 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 239000000443 aerosol Substances 0.000 abstract 1
- 229960005070 ascorbic acid Drugs 0.000 abstract 1
- 235000010323 ascorbic acid Nutrition 0.000 abstract 1
- 239000011668 ascorbic acid Substances 0.000 abstract 1
- 230000003454 betamimetic effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- MGFYIUFZLHCRTH-UHFFFAOYSA-N nitrilotriacetic acid Chemical compound OC(=O)CN(CC(O)=O)CC(O)=O MGFYIUFZLHCRTH-UHFFFAOYSA-N 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Otolaryngology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
Abstract
QUE COMPRENDEN A) UN PRINCIPIO ACTIVO FARMACOLOGICAMENTE EFICAZ, DESTINADO PARA LA ADMINISTRACION INHALATIVA, ESPECIALMENTE PARA EL TRATAMIENTO DE ENFERMEDADES RESPIRATORIAS, EL CUAL SE SELECCIONA A PARTIR DEL GRUPO DE LOS BETAMIMETICOS, ANTICOLINERGICOS, ANTIALERGICOS Y/O ANTIHISTAMINICOS; TENIENDO UNA CONCENTRACION DE 0,001 g/100 ml A 2 g/100 ml DE SOLUCION; Y B) UN FORMADOR DE COMPLEJOS QUE PUEDE SER ACIDO NITRILOTRIACETICO, ACIDO CITRICO, ACIDO ASCORBICO O SUS SALES, SIENDO SU CONCENTRACION ENTRE 10 mg/100 ml Y 100 mg/100 ml DE SOLUCION; DICHAS PREPARACIONES MEDICAMENTOSAS CONTIENEN ADEMAS SUSTANCIAS AUXILIARES Y SABOREANTES, FARMACOLOGICAMENTE INOCUAS Y SE USAN PARA LA PRODUCCION DE AEROSOLES LIBRES DE GAS PROPULSOR, PARA INHALACION
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19653969A DE19653969A1 (de) | 1996-12-20 | 1996-12-20 | Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE32899A1 true PE32899A1 (es) | 1999-04-23 |
Family
ID=7815979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1997001120A PE32899A1 (es) | 1996-12-20 | 1997-12-16 | Nuevas preparaciones medicamentosas acuosas para la produccion de aerosoles libres de gas propulsor |
Country Status (38)
| Country | Link |
|---|---|
| US (3) | US20010008632A1 (es) |
| EP (2) | EP0946146B1 (es) |
| JP (1) | JP4659160B2 (es) |
| KR (1) | KR100496723B1 (es) |
| CN (1) | CN1097455C (es) |
| AR (1) | AR008721A1 (es) |
| AT (1) | ATE235887T1 (es) |
| AU (1) | AU740543B2 (es) |
| BG (1) | BG64433B1 (es) |
| BR (1) | BRPI9713596C1 (es) |
| CA (1) | CA2275392C (es) |
| CO (1) | CO4920211A1 (es) |
| DE (2) | DE19653969A1 (es) |
| DK (1) | DK0946146T3 (es) |
| EE (1) | EE03949B1 (es) |
| EG (1) | EG23981A (es) |
| ES (1) | ES2196388T3 (es) |
| HR (1) | HRP970694B1 (es) |
| HU (2) | HU228494B1 (es) |
| ID (1) | ID22481A (es) |
| IL (1) | IL130464A (es) |
| MY (1) | MY124547A (es) |
| NO (1) | NO320652B1 (es) |
| NZ (1) | NZ336825A (es) |
| PE (1) | PE32899A1 (es) |
| PL (1) | PL189511B1 (es) |
| PT (1) | PT946146E (es) |
| RS (1) | RS49803B (es) |
| RU (1) | RU2219906C2 (es) |
| SA (1) | SA97180756B1 (es) |
| SI (1) | SI0946146T1 (es) |
| SK (1) | SK282910B6 (es) |
| TR (1) | TR199901408T2 (es) |
| TW (1) | TW438605B (es) |
| UA (1) | UA64736C2 (es) |
| UY (1) | UY24813A1 (es) |
| WO (1) | WO1998027959A2 (es) |
| ZA (1) | ZA9711370B (es) |
Families Citing this family (92)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19615422A1 (de) | 1996-04-19 | 1997-11-20 | Boehringer Ingelheim Kg | Zweikammer-Kartusche für treibgasfreie Dosieraerosole |
| DE19733651A1 (de) * | 1997-08-04 | 1999-02-18 | Boehringer Ingelheim Pharma | Wässrige Aerosolzubereitungen enthaltend biologisch aktive Markomoleküle und Verfahren zur Erzeugung entsprechender Aerosole |
| DE19808295A1 (de) | 1998-02-27 | 1999-11-11 | Boehringer Ingelheim Int | Behälter für eine medizinische Flüssigkeit |
| DE19847968A1 (de) * | 1998-10-17 | 2000-04-20 | Boehringer Ingelheim Pharma | Verschlußkappe und Behälter als Zweikammer-Kartusche für Vernebler zur Erzeugung von Aerosolen |
| SE9803770D0 (sv) * | 1998-11-05 | 1998-11-05 | Astra Ab | Dry powder pharmaceutical formulation |
| DE19940713A1 (de) | 1999-02-23 | 2001-03-01 | Boehringer Ingelheim Int | Kartusche für eine Flüssigkeit |
| DE19921693A1 (de) * | 1999-05-12 | 2000-11-16 | Boehringer Ingelheim Pharma | Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika |
| US20040002548A1 (en) * | 1999-05-12 | 2004-01-01 | Boehringer Ingelheim Pharma Kg | Medicament compositions containing anticholinergically-effective compounds and betamimetics |
| US20100197719A1 (en) * | 1999-05-12 | 2010-08-05 | Boehringer Ingelheim Pharma Kg | Medicament compositions containing anticholinergically-effective compounds and betamimetics |
| DE19954516A1 (de) * | 1999-11-12 | 2001-05-17 | Boehringer Ingelheim Int | Epinastin-haltige Lösungen |
| JP2004509920A (ja) * | 2000-09-29 | 2004-04-02 | ボード オブ トラスティーズ オペレーティング ミシガン ステート ユニヴァーシティ | カテコールアミン医薬組成物および方法 |
| UA78690C2 (uk) * | 2000-10-31 | 2007-04-25 | Boehringer Ingelheim Pharma | Лікарська композиція для інгаляційного застосування у вигляді розчину із сіллю тіотропію |
| DE10062712A1 (de) * | 2000-12-15 | 2002-06-20 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Corticosteroiden |
| US20020137764A1 (en) | 2000-10-31 | 2002-09-26 | Karin Drechsel | Inhalable formulation of a solution containing a tiotropium salt |
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| US20020193392A1 (en) * | 2000-11-13 | 2002-12-19 | Christel Schmelzer | Pharmaceutical compositions based on tiotropium salts of salts of salmeterol |
| DE10111843A1 (de) * | 2001-03-13 | 2002-09-19 | Boehringer Ingelheim Pharma | Verbindungen zur Behandlung von inflammatorischen Erkrankungen |
| GB2375958B (en) * | 2001-04-09 | 2005-03-02 | George Margetts | The use of steroids to lower the levels of cortisol |
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| PL208686B1 (pl) * | 2001-09-18 | 2011-05-31 | Nycomed Danmark Aps | Kompozycja w postaci roztworu wodnego do leczenia przeziębienia oraz zastosowanie połączenia ipratropium lub jego soli i ksylometazoliny lub jej soli |
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| JP2006513129A (ja) * | 2001-10-26 | 2006-04-20 | デイ エルピー | 小児喘息の症状を緩和するためのアルブテロール吸入溶液、システム、キット及び方法 |
| AU3297402A (en) * | 2001-10-26 | 2003-10-30 | Dey, L.P. | An albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease |
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| EP1531795A4 (en) | 2002-05-02 | 2011-02-23 | Harvard College | FORMULATIONS FOR LIMITING THE RETENTION OF LUNG INFECTIONS |
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| CN109925300A (zh) * | 2017-12-19 | 2019-06-25 | 北京盈科瑞创新药物研究有限公司 | 一种福多司坦雾化吸入用溶液制剂及其制备方法 |
| US20230270754A1 (en) | 2020-07-31 | 2023-08-31 | Chemo Research, S.L. | Combination therapy for inhalation administration |
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| JPH0645538B2 (ja) * | 1987-09-30 | 1994-06-15 | 日本化薬株式会社 | ニトログリセリンスプレー剤 |
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| EP0726075A1 (en) * | 1995-02-08 | 1996-08-14 | Therapicon Srl | Pharmaceutical non-inorganic saline solutions for endonasal administration |
| PT835098E (pt) * | 1995-06-27 | 2002-12-31 | Boehringer Ingelheim Pharma | Nova composicao farmaceutica estavel para a producao de aerossois sem gas propulsante |
| DE19536902A1 (de) * | 1995-10-04 | 1997-04-10 | Boehringer Ingelheim Int | Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung |
| DE19536916A1 (de) * | 1995-10-04 | 1997-04-10 | Boehringer Ingelheim Kg | Inhalative Applikation von 2-Amino-6n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol, insbesondere seines (-)-Enantiomeren, sowie deren pharmakologisch verträgliche Säureadditionssalze |
| EP0808627A2 (de) * | 1996-05-22 | 1997-11-26 | Hoechst Aktiengesellschaft | Verwendung nicht-peptidischer Bradykinin-Antagonisten zur Behandlung und Prävention von chronisch-fibrogenetischen Lebererkrankungen, akuten Lebererkrankungen und den damit verbundenen Komplikationen |
| DE19620509A1 (de) * | 1996-05-22 | 1997-11-27 | Hoechst Ag | Verwendung nicht-peptidischer Bradykinin-Antagonisten zur Behandlung und Prävention von chronisch-fibrogenetischen Lebererkrankungen, akuten Lebererkrankungen und den damit verbundenen Komplikationen |
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| US20030215396A1 (en) * | 1999-09-15 | 2003-11-20 | Boehringer Ingelheim Pharma Kg | Method for the production of propellant gas-free aerosols from aqueous medicament preparations |
| US20060239930A1 (en) * | 1997-08-04 | 2006-10-26 | Herbert Lamche | Process for nebulizing aqueous compositions containing highly concentrated insulin |
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-
1996
- 1996-12-20 DE DE19653969A patent/DE19653969A1/de not_active Ceased
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1997
- 1997-12-16 US US09/331,023 patent/US20010008632A1/en not_active Abandoned
- 1997-12-16 EP EP97952949A patent/EP0946146B1/de not_active Expired - Lifetime
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- 1997-12-16 RU RU99116025/15A patent/RU2219906C2/ru active
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- 1997-12-16 DK DK97952949T patent/DK0946146T3/da active
- 1997-12-16 HU HU0600044A patent/HU228494B1/hu unknown
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- 1997-12-16 TR TR1999/01408T patent/TR199901408T2/xx unknown
- 1997-12-16 AT AT97952949T patent/ATE235887T1/de active
- 1997-12-16 EP EP02010785A patent/EP1230916A3/de not_active Withdrawn
- 1997-12-16 CN CN97180735A patent/CN1097455C/zh not_active Expired - Lifetime
- 1997-12-16 WO PCT/EP1997/007062 patent/WO1998027959A2/de not_active Ceased
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- 1997-12-16 RS YUP-284/99A patent/RS49803B/sr unknown
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- 1997-12-18 EG EG135397A patent/EG23981A/xx active
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- 1997-12-20 TW TW086119428A patent/TW438605B/zh not_active IP Right Cessation
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2008
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