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ES2157005T3 - Uso del acido boswellico y sus derivados para la inhibicion de la actividad normal y elevada de la elastasa de leucocitos o de la plasmina. - Google Patents

Uso del acido boswellico y sus derivados para la inhibicion de la actividad normal y elevada de la elastasa de leucocitos o de la plasmina.

Info

Publication number
ES2157005T3
ES2157005T3 ES96929309T ES96929309T ES2157005T3 ES 2157005 T3 ES2157005 T3 ES 2157005T3 ES 96929309 T ES96929309 T ES 96929309T ES 96929309 T ES96929309 T ES 96929309T ES 2157005 T3 ES2157005 T3 ES 2157005T3
Authority
ES
Spain
Prior art keywords
inhibition
normal
derivative
acid
plasmina
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96929309T
Other languages
English (en)
Other versions
ES2157005T5 (es
Inventor
Hermann P T Ammon
Hasan Safayhi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7770222&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2157005(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of ES2157005T3 publication Critical patent/ES2157005T3/es
Application granted granted Critical
Publication of ES2157005T5 publication Critical patent/ES2157005T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/324—Boswellia, e.g. frankincense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Reproductive Health (AREA)
  • Biotechnology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LA INVENCION SE REFIERE AL USO DEL ACIDO BOSWELLICO PURO, UNA SAL FISIOLOGICAMENTE ACEPTABLE, UN DERIVADO, UNA SAL DEL DERIVADO O UNA PREPARACION VEGETAL QUE CONTIENE ACIDO BOSWELLICO PARA LA PROFILAXIS Y/O CONTROL DE ENFERMEDADES, QUE SON PRODUCIDAS POR UN INCREMENTO DE LA ACTIVIDAD DE LA LEUCOCITO ELASTASA O DE LA PLASMINA O QUE SE PUEDEN TRATAR MEDIANTE LA INHIBICION DE LA ACTIVIDAD NORMAL DE LA LEUCOCITO ELASTASA O DE LA PLASMINA, TANTO EN MEDICINA COMO EN VETERINARIA. LA INVENCION SE REFIERE ADEMAS AL USO DEL ACIDO BOSWELLICO PURO O DE UNA SAL FISIOLOGICAMENTE ACEPTABLE, UN DERIVADO, UNA SAL DEL DERIVADO O UNA PREPARACION VEGETAL QUE CONTIENE ACIDO BOSWELLICO PARA LA PREPARACION DE UN MEDICAMENTO PARA EL TRATAMIENTO DE ENFERMEDADES QUE SON PRODUCIDAS POR UN INCREMENTO DE LA ACTIVIDAD DE LA LEUCOCITO ELASTASA O DE LA PLASMINA O QUE SE PUEDEN TRATAR MEDIANTE LA INHIBICION DE LA ACTIVIDAD NORMAL DE LA LEUCOCITO ELASTASA O DE LA PLASMINA, TANTO EN MEDICINA COMO EN VETERINARIA.
ES96929309T 1995-08-23 1996-08-22 Uso del acido boswellico y sus derivados para la inhibicion de la actividad normal y elevada de la elastasa de leucocitos o de la plasmina. Expired - Lifetime ES2157005T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19531067 1995-08-23
DE19531067A DE19531067A1 (de) 1995-08-23 1995-08-23 Verwendung von Boswelliasäure und ihren Derivaten zur Hemmung der normalen und gesteigerten Leukozytenelastase- oder Plasminaktivität

Publications (2)

Publication Number Publication Date
ES2157005T3 true ES2157005T3 (es) 2001-08-01
ES2157005T5 ES2157005T5 (es) 2005-07-16

Family

ID=7770222

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96929309T Expired - Lifetime ES2157005T5 (es) 1995-08-23 1996-08-22 Uso del acido boswellico y sus derivados para la inhibicion de la actividad normal y elevada de la elastasa de leucocitos o de la plasmina.

Country Status (9)

Country Link
US (4) US20020010168A1 (es)
EP (1) EP0854709B2 (es)
JP (1) JPH11511448A (es)
AT (1) ATE200422T1 (es)
DE (2) DE19531067A1 (es)
DK (1) DK0854709T4 (es)
ES (1) ES2157005T5 (es)
PT (1) PT854709E (es)
WO (1) WO1997007796A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI266760B (en) 2000-03-20 2006-11-21 Kvaerner Process Tech Ltd Process for the preparation of propane-1,3-diol
US6492429B1 (en) 2000-07-10 2002-12-10 N.V. Nutricia Composition for the treatment of osteoarthritis
DE10041217A1 (de) * 2000-08-22 2002-03-14 Henkel Kgaa Verwendung von Dihydroboswelliasäuren oder hydrierten Extrakten aus Boswellia zur prophylaktischen und/oder therapeutischen Behandlung von unerwünschten körperlichen oder seelischen Zuständen
WO2002024173A2 (de) * 2000-09-20 2002-03-28 R.P. Scherer Gmbh & Co. Kg Orale zubereitungsformen von extrakten aus boswellia
WO2002066491A1 (en) * 2001-02-15 2002-08-29 Sabinsa Corporation Water soluble boswellic acids, their preparation and use for treating imflammatory conditions
ITMI20031311A1 (it) * 2003-06-27 2004-12-28 Indena Spa Formulazioni per il trattamento di disturbi artrosici.
AU2005204685B2 (en) 2004-01-07 2007-06-21 E-L Management Corporation Cosmetic composition and method for retarding hair growth
JP4732454B2 (ja) * 2004-07-08 2011-07-27 ライラ ニュートラシューティカルズ 抗糖尿病性および抗炎症性を有するコロソリン酸の新規構造類似体
RU2266748C1 (ru) * 2004-11-16 2005-12-27 Открытое акционерное общество Завод экологической техники и экопитания "ДИОД" /ОАО "ДИОД"/ Средство, обладающее противовоспалительной активностью
EP2187968A4 (en) 2007-08-21 2013-02-20 Univ Texas THERMOKINETIC MIXING FOR PHARMACEUTICAL APPLICATIONS
WO2009092040A2 (en) * 2008-01-17 2009-07-23 Gary Dean Bennett Topical pain formulation
US20090298938A1 (en) * 2008-03-11 2009-12-03 Council Of Scientific & Industrial Research Use of semi synthetic analogues of boswellic acids for anticancer activity
DE102008017496A1 (de) 2008-04-04 2009-10-15 Medeon Pharmaceuticals Gmbh Verwendung von Boswelliasäure und Boswelliasäurederivaten zur Herstellung von Arzneimitteln zur Therapie von Multipler Sklerose
DE102008015607A1 (de) * 2008-03-26 2009-10-15 Universität Tübingen Verwendung von Boswelliasäuren und synthetischen Boswelliasäurederivaten zur Hemmung der mikrosomalen Prostaglandin E2 Synthase und des Cathepsin G
US20100112101A1 (en) * 2008-05-06 2010-05-06 Laila Impex Bio-availability/bio-efficacy enhancing activity of stevia rebaudiana and extracts and fractions and compounds thereof
DK3150198T3 (da) * 2010-04-07 2021-11-01 Vertex Pharma Farmaceutiske sammensætninger af 3-(6-(1-(2,2-difluorbenzo[d][1,3]dioxol-5-yl)-cyclopropancarboxamido)-3-methylpyriodin-2-yl)benzoesyre og indgivelse deraf
WO2012116238A1 (en) * 2011-02-23 2012-08-30 Dispersol Technologies, Llc PHARMACEUTICAL FORMULATIONS OF ACETYL-11-KETO-β-BOSWELLIC ACID, DIINDOLYLMETHANE, AND CURCUMIN FOR PHARMACEUTICAL APPLICATIONS
CN103889434B (zh) 2011-06-21 2017-02-15 Bvw控股公司 含有乳香酸的医疗装置
DE102017005429A1 (de) * 2017-06-08 2018-12-13 Adelheid Maria Zech Zubereitungen auf Basis Weihrauch zur Verwendung bei der Behandlung einer Erkrankung der Atmungswege eines Lebewesens
US9975917B1 (en) 2017-09-20 2018-05-22 King Saud University Pentacyclic triterpenoidal derivatives
CN116102611A (zh) * 2021-11-10 2023-05-12 中国医学科学院药物研究所 11-羰基-β-乙酰乳香酸治疗肺损伤及肺纤维化的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4501734A (en) * 1981-03-06 1985-02-26 Wakunaga Yakuhin Kabushiki Kaisha Promotion of absorption of drugs administered through the alimentary system
US5064823A (en) * 1988-08-24 1991-11-12 Research Triangle Institute Pentacyclic triterpenoid compounds as topoisomerase inhibitors or cell differentiation inducers
CA1330944C (en) † 1988-08-24 1994-07-26 De-Hua Li Pentacyclic triterpenoid compounds as topoisomerase inhibitors or cell differentiation inducers
DE4201903B4 (de) * 1992-01-24 2004-04-15 Hermann P.T. Prof. Dr.Med. Ammon Pharmazeutische Verwendung von Boswelliasäuren
US5494668A (en) * 1994-07-11 1996-02-27 Patwardhan; Bhushan Method of treating musculoskeletal disease and a novel composition therefor
DE4444288A1 (de) * 1994-12-13 1996-06-20 Rainer Dr Med Etzel Verwendung von Weihrauch zur Behandlung der Alzheimer-Krankheit
DE4445728A1 (de) † 1994-12-21 1996-06-27 Simmet Th Prof Dr Verwendung von Boswelliasäure zur Behandlung von Hirntumoren
US5629351A (en) * 1995-04-13 1997-05-13 Council Of Scientific & Industrial Research Boswellic acid compositions and preparation thereof
JPH10107808A (ja) * 1996-10-03 1998-04-24 Fujitsu Ltd セル交換システムにおける仮想コネクションの設定制御方式
US5888514A (en) * 1997-05-23 1999-03-30 Weisman; Bernard Natural composition for treating bone or joint inflammation

Also Published As

Publication number Publication date
US20100166670A1 (en) 2010-07-01
DK0854709T4 (da) 2005-04-11
WO1997007796A1 (de) 1997-03-06
PT854709E (pt) 2001-08-30
US20020010168A1 (en) 2002-01-24
DK0854709T3 (da) 2001-06-18
JPH11511448A (ja) 1999-10-05
US20050209169A1 (en) 2005-09-22
US20070129317A1 (en) 2007-06-07
DE19531067A1 (de) 1997-02-27
DE59606784D1 (de) 2001-05-17
EP0854709B2 (de) 2005-02-23
ATE200422T1 (de) 2001-04-15
EP0854709A1 (de) 1998-07-29
EP0854709B1 (de) 2001-04-11
ES2157005T5 (es) 2005-07-16

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