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PE20191841A1 - Procesos para la produccion de linfocitos infiltrantes de tumores y usos de ellos en inmunoterapia - Google Patents

Procesos para la produccion de linfocitos infiltrantes de tumores y usos de ellos en inmunoterapia

Info

Publication number
PE20191841A1
PE20191841A1 PE2019001976A PE2019001976A PE20191841A1 PE 20191841 A1 PE20191841 A1 PE 20191841A1 PE 2019001976 A PE2019001976 A PE 2019001976A PE 2019001976 A PE2019001976 A PE 2019001976A PE 20191841 A1 PE20191841 A1 PE 20191841A1
Authority
PE
Peru
Prior art keywords
tils
infiltrating lymphocytes
immunotherapy
tumors
processes
Prior art date
Application number
PE2019001976A
Other languages
English (en)
Inventor
Seth Wardell
James Bender
Michael T Lotze
Original Assignee
Iovance Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=61569356&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20191841(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Iovance Biotherapeutics Inc filed Critical Iovance Biotherapeutics Inc
Publication of PE20191841A1 publication Critical patent/PE20191841A1/es

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    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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Abstract

La presente invencion proporciona mejores metodos y/o metodos acortados para expandir linfocitos infiltrantes de tumores (TILs) y producir poblaciones terapeuticas de TILs, incluyendo nuevos metodos para expandir las poblaciones de TILs en un sistema cerrado que llevan a una mayor eficacia, mayor fenotipo y mayor salud metabolica de los TILs en un periodo de tiempo mas corto, mientras permite una contaminacion microbiana reducida asi como menores costos. Estos TILs se usan en regimenes de tratamiento terapeuticos
PE2019001976A 2017-03-29 2018-01-05 Procesos para la produccion de linfocitos infiltrantes de tumores y usos de ellos en inmunoterapia PE20191841A1 (es)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US201762478506P 2017-03-29 2017-03-29
US201762539410P 2017-07-31 2017-07-31
US201762548306P 2017-08-21 2017-08-21
US201762554538P 2017-09-05 2017-09-05
US201762559374P 2017-09-15 2017-09-15
US201762567121P 2017-10-02 2017-10-02
US201762577655P 2017-10-26 2017-10-26
US201762582874P 2017-11-07 2017-11-07
US201762596374P 2017-12-08 2017-12-08
PCT/US2018/012633 WO2018182817A1 (en) 2017-03-29 2018-01-05 Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy

Publications (1)

Publication Number Publication Date
PE20191841A1 true PE20191841A1 (es) 2019-12-31

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PE2019001976A PE20191841A1 (es) 2017-03-29 2018-01-05 Procesos para la produccion de linfocitos infiltrantes de tumores y usos de ellos en inmunoterapia

Country Status (35)

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US (60) US10894063B2 (es)
EP (6) EP3601533B1 (es)
JP (6) JP7169291B2 (es)
KR (2) KR20240114787A (es)
CN (1) CN110785486A (es)
AU (2) AU2018243355B2 (es)
BR (1) BR112019020326A2 (es)
CA (1) CA3057975A1 (es)
CL (2) CL2019002769A1 (es)
CO (1) CO2019011995A2 (es)
CR (1) CR20190487A (es)
CY (1) CY1124136T1 (es)
DK (3) DK3730608T3 (es)
EC (1) ECSP19077884A (es)
ES (3) ES3008832T3 (es)
FI (2) FI3722415T3 (es)
HR (3) HRP20210677T1 (es)
HU (3) HUE070176T2 (es)
IL (2) IL305198A (es)
JO (1) JOP20190224A1 (es)
LT (3) LT3722415T (es)
MA (2) MA68598B1 (es)
MD (3) MD3601533T2 (es)
MX (2) MX2019011768A (es)
PE (1) PE20191841A1 (es)
PH (1) PH12019502247A1 (es)
PL (3) PL3601533T3 (es)
PT (3) PT3601533T (es)
RS (3) RS61863B1 (es)
SG (1) SG11201908994RA (es)
SI (3) SI3730608T1 (es)
SM (3) SMT202100298T1 (es)
TN (1) TN2019000273A1 (es)
TW (1) TWI799402B (es)
WO (1) WO2018182817A1 (es)

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