[go: up one dir, main page]

PE20151300A1 - Composicion antifungica topica para el tratamiento de onicomicosis - Google Patents

Composicion antifungica topica para el tratamiento de onicomicosis

Info

Publication number
PE20151300A1
PE20151300A1 PE2015001580A PE2015001580A PE20151300A1 PE 20151300 A1 PE20151300 A1 PE 20151300A1 PE 2015001580 A PE2015001580 A PE 2015001580A PE 2015001580 A PE2015001580 A PE 2015001580A PE 20151300 A1 PE20151300 A1 PE 20151300A1
Authority
PE
Peru
Prior art keywords
treatment
onichomycosis
antifungal composition
composition
topical antifungal
Prior art date
Application number
PE2015001580A
Other languages
English (en)
Inventor
Federico Mailland
Michela Legora
Daniela Ceriani
Giuliana Iob
Original Assignee
Polichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50029007&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20151300(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Polichem Sa filed Critical Polichem Sa
Publication of PE20151300A1 publication Critical patent/PE20151300A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE REFIERE A UNA COMPOSICION QUE CONSISTE DE: (A) TERBINAFINA O UNA SAL FARMACEUTICAMENTE ACEPTABLE DEL MISMO, COMO AGENTE ANTIMICOTICO; (B) HIDROXIPROPIL QUITOSANO COMO UN AGENTE FORMADOR DE PELICULA; (C) AGUA; Y (D) POR LO MENOS UN ALCANOL INFERIOR COMO SOLVENTE. PREFERENTEMENTE, DICHA COMPOSICION ES UN ESMALTE DE UNAS, UTIL EN EL TRATAMIENTO DE ONICOMICOSIS POR ADMINISTRACION TOPICA DE DICHO ESMALTE DE UNAS A UN PACIENTE EN NECESIDAD DE TAL TRATAMIENTO
PE2015001580A 2013-02-07 2014-01-23 Composicion antifungica topica para el tratamiento de onicomicosis PE20151300A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361761953P 2013-02-07 2013-02-07
US201361781560P 2013-03-14 2013-03-14

Publications (1)

Publication Number Publication Date
PE20151300A1 true PE20151300A1 (es) 2015-09-16

Family

ID=50029007

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2015001580A PE20151300A1 (es) 2013-02-07 2014-01-23 Composicion antifungica topica para el tratamiento de onicomicosis

Country Status (34)

Country Link
US (3) US8697753B1 (es)
EP (1) EP2953621B1 (es)
JP (1) JP6420258B2 (es)
KR (1) KR102200788B1 (es)
CN (1) CN105050592B (es)
AU (1) AU2014214166B2 (es)
BR (1) BR112015018798B1 (es)
CA (1) CA2900127C (es)
CL (1) CL2015002191A1 (es)
CR (1) CR20150377A (es)
CY (1) CY1121841T1 (es)
DK (1) DK2953621T3 (es)
EA (1) EA036061B1 (es)
EC (1) ECSP15033898A (es)
ES (1) ES2729373T3 (es)
HR (1) HRP20191243T1 (es)
HU (1) HUE045000T2 (es)
IL (1) IL240334B (es)
LT (1) LT2953621T (es)
ME (1) ME03507B (es)
MX (1) MX361880B (es)
NZ (1) NZ709668A (es)
PE (1) PE20151300A1 (es)
PH (1) PH12015501739B1 (es)
PL (1) PL2953621T3 (es)
PT (1) PT2953621T (es)
RS (1) RS58990B1 (es)
SG (1) SG11201505275YA (es)
SI (1) SI2953621T1 (es)
TN (1) TN2015000316A1 (es)
TW (1) TWI658839B (es)
UY (1) UY35307A (es)
WO (1) WO2014122024A1 (es)
ZA (1) ZA201504880B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8697753B1 (en) * 2013-02-07 2014-04-15 Polichem Sa Method of treating onychomycosis
KR101580077B1 (ko) * 2015-03-28 2015-12-24 한국콜마주식회사 시크로피록스 함유 네일락카 조성물
GB201605127D0 (en) * 2016-03-25 2016-05-11 Blueberry Therapeutics Ltd Composition and methods of treatment
DE102019003486B4 (de) * 2019-05-17 2021-03-18 L/N Health And Beauty Aps Zusammensetzungen zur Behandlung der Onychomykose
KR20220118492A (ko) * 2019-12-20 2022-08-25 글락소스미스클라인 컨슈머 헬스케어 홀딩스 (유에스) 엘엘씨 조갑진균증을 치료하기 위한 국소 제약 조성물

Family Cites Families (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3883545A (en) 1968-08-31 1975-05-13 Hoechst Ag Certain 1-hydroxy-2-pyridones
AT354187B (de) 1976-11-22 1979-12-27 Hoffmann La Roche Fungizides mittel
CY1410A (en) 1979-08-22 1988-04-22 Sandoz Ag Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals
DE3045914A1 (de) 1980-12-05 1982-07-22 Bayer Ag, 5090 Leverkusen Antimykotische mittel mit hoher wirkstoff-freisetzung in form von elastischen fluessig-pflastern
DE3045915A1 (de) 1980-12-05 1982-07-08 Bayer Ag, 5090 Leverkusen Antimykotische mittel mit hoher wirkstoff-freisetzung in form von elastischen fluessig-pflastern
DE3245784A1 (de) 1982-12-10 1984-06-14 Wella Ag, 6100 Darmstadt Kosmetisches mittel auf der basis von quaternaeren chitosanderivaten, neue quaternaere chitosanderivate sowie verfahren zu ihrer herstellung
DE3502833A1 (de) 1985-01-29 1986-07-31 Wella Ag, 6100 Darmstadt Kosmetische mittel auf der basis von quaternaeren chitosanderivaten, neue quaternaere hydroxyethyl-substituierte chitosanderivate sowie verfahren zu ihrer herstellung
DE3513277A1 (de) 1985-04-13 1986-10-23 Wella Ag, 6100 Darmstadt Kosmetische mittel auf der basis von quaternaeren hydroxyalkyl-substituierten chitosanderivaten
AU599064B2 (en) 1985-11-04 1990-07-12 Dermatological Products Of Texas Film-forming, pharmaceutical vehicles for application of medicaments to nails, pharmaceutical compositions based on those vehicles, and methods of using same
DE3541305A1 (de) 1985-11-22 1987-05-27 Wella Ag Kosmetische mittel auf der basis von n-hydroxypropylchitosanen, neue n-hydroxypropyl-chitosane sowie verfahren zu ihrer herstellung
DE3544983A1 (de) 1985-12-19 1987-06-25 Hoechst Ag Antimykotisch wirksamer nagellack
DE3545929A1 (de) 1985-12-23 1987-06-25 Ceag Licht & Strom Gehaeuse
SE460713B (sv) 1986-04-22 1989-11-13 Atlas Copco Ab Hydrauliskt momentimpulsverk
US4946870A (en) 1986-06-06 1990-08-07 Union Carbide Chemicals And Plastics Company Inc. Delivery systems for pharmaceutical or therapeutic actives
DE3703760A1 (de) 1987-02-07 1988-08-18 Wella Ag Kosmetisches mittel auf der basis von n-hydroxypropylisopropyletherchitosanen, sowie neue n-hydroxypropylisopropyletherderivate des chitosans
HU200914B (en) 1987-03-09 1990-09-28 Horvath Gyoengyi Lengyelne Process for producing new medical dosage unit suitable for local treatment of fungus infection of nails
DE3720147A1 (de) 1987-06-16 1988-12-29 Hoechst Ag Antimykotisch wirksamer nagellack sowie verfahren zu dessen herstellung
DE3723811A1 (de) 1987-07-18 1989-01-26 Wella Ag Nagellack auf der basis von o-benzyl-n-hydroxyalkylchitosanen sowie neue o-benzyl-n-hydroxyalkylderivate des chitosans
CA2008775C (en) 1989-02-24 1998-12-22 Alberto Ferro Nail lacquer
FR2673537B1 (fr) 1991-03-08 1993-06-11 Oreal Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes.
DE4108664C2 (de) 1991-03-16 1995-03-09 Scheller Cosmetics Gmbh Dr Nagellack und Verwendung desselben
HU223343B1 (hu) 1991-05-20 2004-06-28 Novartis Ag. Allil-amin-származékot tartalmazó gyógyászati készítmények és eljárás azok előállítására
US6005001A (en) 1991-05-20 1999-12-21 Novartis Ag (Formerly Sandoz Ag) Pharmaceutical composition
HU219480B (hu) 1991-05-23 2001-04-28 Novartis Ag. Eljárás gombás körömmegbetegségek ellen helyileg alkalmazható, allil-amin-származékot tartalmazó gyógyászati készítmények előállítására
DE4212105A1 (de) 1992-04-10 1993-10-14 Roehm Pharma Gmbh Nagellack zur Behandlung von Onychomykosen
JPH05339152A (ja) 1992-06-09 1993-12-21 Nippon Soda Co Ltd 皮膚病変局所投与薬剤含有キトサン誘導体フィルム剤
JPH06211651A (ja) 1993-01-12 1994-08-02 Hisamitsu Pharmaceut Co Inc 爪白癬治療用組成物
DE19518262A1 (de) 1995-05-18 1996-11-21 Hoechst Ag Die Verwendung von Glyceryltriacetat zur Behandlung von Onychomykosen
US5391367A (en) 1993-07-28 1995-02-21 Pfizer Inc. Antifungal nail solution
US5487776A (en) 1994-03-17 1996-01-30 Nimni; Marcel Anti-fungal nail lacquer and method therefor
WO1996011710A1 (en) 1994-10-13 1996-04-25 Hisamitsu Pharmaceutical Co., Inc. External preparation for nail ringworm
JP2951725B2 (ja) 1994-10-13 1999-09-20 久光製薬株式会社 爪白癬用外用組成物
US5696164A (en) 1994-12-22 1997-12-09 Johnson & Johnson Consumer Products, Inc. Antifungal treatment of nails
DE19503423A1 (de) 1995-02-03 1996-08-08 Beiersdorf Ag Antiadhäsive Wirkstoffe
AU697742B2 (en) 1995-03-03 1998-10-15 Intermune, Inc. Treatment of cytokine growth factor caused disorders
DE19604190A1 (de) 1996-02-06 1997-08-07 Hoechst Ag Nagelwachstumsfördernde Zubereitungen
ATE443755T1 (de) 1996-08-01 2009-10-15 Dale Wallis Erkennung, vorbeugung und behandlung papillomatöser digitaler dermatitis
JP4253047B2 (ja) 1996-09-27 2009-04-08 杏林製薬株式会社 被膜形成性抗真菌剤組成物
JP4227677B2 (ja) 1996-12-10 2009-02-18 杏林製薬株式会社 被膜形成性抗真菌剤組成物
FR2761886B1 (fr) 1997-04-14 2000-05-05 Virbac Sa Compositions contenant au moins un polymere cationique et au moins une molecule active contenue dans au moins un vecteur micro ou nanoparticulaire, et leur utilisation pour le traitement de surfaces vivantes ou inertes
US5991438A (en) 1997-07-31 1999-11-23 Hewlett-Packard Company Color halftone error-diffusion with local brightness variation reduction
US6224887B1 (en) 1998-02-09 2001-05-01 Macrochem Corporation Antifungal nail lacquer and method using same
JP2002506820A (ja) 1998-03-17 2002-03-05 ビー マーゴリン、ソロモン 局所用防腐組成物および方法
US6231875B1 (en) 1998-03-31 2001-05-15 Johnson & Johnson Consumer Companies, Inc. Acidified composition for topical treatment of nail and skin conditions
ATE269067T1 (de) 1998-04-17 2004-07-15 Bertek Pharm Inc Topische formulierungen zur behandlung von nagel pilzerkrankungen
US6306375B1 (en) 1998-05-01 2001-10-23 The Procter & Gamble Company Long wear nail polish having defined surface properties
US5965111A (en) 1998-05-01 1999-10-12 The Procter & Gamble Company Fast drying water-borne nail polish
US6284234B1 (en) 1998-08-04 2001-09-04 Johnson & Johnson Consumer Companies, Inc. Topical delivery systems for active agents
DE59911740D1 (de) 1998-09-10 2005-04-14 Bioequal Ag Muttenz Topisch anwendbare mittel gegen nagelpilzerkrankungen
DE19841796A1 (de) 1998-09-12 2000-03-16 Beiersdorf Ag Kombinationen von Antiadhäsiva (Kohlenhydrate) und Mikrobiziden
US6159977A (en) 1998-11-16 2000-12-12 Astan, Inc. Therapeutic anti-fungal nail preparation
ATE249811T1 (de) 1999-02-09 2003-10-15 Cognis Deutschland Gmbh Verwendung von nanoskaligen chitosanen
ES2199094T1 (es) 1999-08-19 2004-02-16 Lavipharm Sa Polimeros formadores de pelicula, procedimientos de uso y aplicaciones de los mismos.
DE19960632A1 (de) 1999-12-16 2001-07-05 Cognis Deutschland Gmbh Kosmetische Mittel enthaltend natürliche Chitosane
DE10061801A1 (de) 2000-01-03 2001-07-12 Karl Kraemer Zubereitungen zur atraumatischen Nagelentfernung
NZ520749A (en) 2000-02-16 2004-06-25 Bentley Pharmaceuticals Inc Pharmaceutical composition comprising a drug, a membrane-compatible permeation enhancer and a polymeric film-forming agent
DE10011081A1 (de) 2000-03-09 2001-09-13 Aventis Pharma Gmbh Antiinfektive Wirkstoffkombinationen und ihre Verwendung zur topischen Behandlung von Pilzerkrankungen der Fuß- und Fingernägel
US7074392B1 (en) 2000-03-27 2006-07-11 Taro Pharmaceutical Industries Limited Controllled delivery system of antifungal and keratolytic agents for local treatment of fungal infections
DE10035991A1 (de) * 2000-07-24 2002-02-14 Polichem Sa Nagellackzusammensetzung
GB0019283D0 (en) 2000-08-04 2000-09-27 Novartis Ag Organic compounds
JP4899139B2 (ja) 2000-08-10 2012-03-21 株式会社ポーラファルマ 抗真菌医薬組成物
US6676953B2 (en) 2001-01-26 2004-01-13 Don L. Hexamer Antifungal composition and method for human nails
US20030118655A1 (en) 2001-12-21 2003-06-26 Nikhil Kundel Film forming liquid composition
US6921529B2 (en) 2002-07-29 2005-07-26 Joseph C. Maley Treatment modality and method for fungal nail infection
US8404751B2 (en) 2002-09-27 2013-03-26 Hallux, Inc. Subunguicide, and method for treating onychomycosis
EP1635770B1 (en) 2003-03-21 2009-05-27 Nexmed Holdings, Inc. Antifungal nail coat and method of use
EP1491202A1 (en) 2003-06-23 2004-12-29 Polichem S.A. Nail restructuring compositions for topical application
WO2005011565A2 (fr) 2003-07-29 2005-02-10 Pierre Fabre Dermo-Cosmetique Vernis a ongles a action antimycosique
AR045241A1 (es) 2003-08-12 2005-10-19 Novartis Consumer Health Sa Composicion topica que comprende terbinafina e hidrocortisona
US20050238672A1 (en) 2004-04-27 2005-10-27 Nimni Marcel E Antifungal drug delivery
EP1763341A2 (en) 2004-07-02 2007-03-21 Warner-Lambert Company LLC Compositions and methods for treating pathological infections
FR2892023B1 (fr) 2005-10-14 2009-09-25 Galderma Sa Composition pharmaceutique a base d'amorolfine et d'agent filmogene hydrosoluble pour application ungueale et peri-ungueale
EP1958638A1 (en) 2007-02-14 2008-08-20 Polichem S.A. Use of chitosans to increase nail growth rate
EP1958639A1 (en) 2007-02-14 2008-08-20 Polichem S.A. Use of chitosans for the treatment of nail inflammatory diseases
EP1958613A1 (en) * 2007-02-15 2008-08-20 Polichem S.A. Dermal film-forming liquid formulations for drug release to skin
WO2008121709A1 (en) 2007-03-30 2008-10-09 Transport Pharmaceuticals, Inc. Pharmaceutical formulations for iontophoretic delivery of an anti-fungal drug
CN102159202A (zh) 2008-07-23 2011-08-17 靶向递送技术有限公司 施用局部抗真菌制剂治疗真菌感染的方法
US7903569B2 (en) 2008-11-25 2011-03-08 At&T Intellectual Property I, L.P. Diagnosing network problems in an IPV6 dual stack network
EP2434892B1 (en) 2009-05-29 2015-08-19 Palau Pharma, S.A. Azole antifungal compositions
FR2954163B1 (fr) 2009-12-18 2012-03-16 Galderma Pharma Sa Utilisation d'un tensioactif cationique, avantageu-sement amphotere, pour la preparation d'une composition antifongique applicable sur l'ongle
JP5339152B2 (ja) 2009-12-18 2013-11-13 横河電機株式会社 電空変換器
WO2011079234A2 (en) 2009-12-23 2011-06-30 Nuvo Research Inc. Highly permeating terbinafine formulation
EP2345643A1 (en) 2009-12-29 2011-07-20 Polichem S.A. New tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof
RU2432158C1 (ru) 2010-07-28 2011-10-27 Закрытое акционерное общество "Институт прикладной нанотехнологии" Профилактический бактерицидный лак для обработки ногтей
US8697753B1 (en) * 2013-02-07 2014-04-15 Polichem Sa Method of treating onychomycosis

Also Published As

Publication number Publication date
US9107877B2 (en) 2015-08-18
AU2014214166B2 (en) 2018-07-26
HRP20191243T1 (hr) 2019-11-01
US8697753B1 (en) 2014-04-15
EP2953621B1 (en) 2019-05-01
IL240334A0 (en) 2015-09-24
LT2953621T (lt) 2019-06-10
PT2953621T (pt) 2019-06-07
AU2014214166A2 (en) 2015-09-03
IL240334B (en) 2019-11-28
DK2953621T3 (da) 2019-06-17
TWI658839B (zh) 2019-05-11
CY1121841T1 (el) 2020-07-31
US10172811B2 (en) 2019-01-08
TW201440810A (zh) 2014-11-01
PH12015501739A1 (en) 2015-10-19
US20150366822A1 (en) 2015-12-24
JP2016507540A (ja) 2016-03-10
MX361880B (es) 2018-12-18
JP6420258B2 (ja) 2018-11-07
RS58990B1 (sr) 2019-08-30
ES2729373T3 (es) 2019-11-04
PH12015501739B1 (en) 2015-10-19
ME03507B (me) 2020-04-20
MX2015010203A (es) 2016-04-28
BR112015018798A2 (pt) 2017-07-18
UY35307A (es) 2014-06-30
CA2900127A1 (en) 2014-08-14
CN105050592A (zh) 2015-11-11
HUE045000T2 (hu) 2019-11-28
EA036061B1 (ru) 2020-09-22
US20140296347A1 (en) 2014-10-02
ZA201504880B (en) 2016-12-21
EA201500830A1 (ru) 2016-05-31
AU2014214166A1 (en) 2015-08-13
SG11201505275YA (en) 2015-08-28
TN2015000316A1 (en) 2017-01-03
CR20150377A (es) 2015-09-24
WO2014122024A1 (en) 2014-08-14
BR112015018798B1 (pt) 2022-03-29
CL2015002191A1 (es) 2016-05-20
KR102200788B1 (ko) 2021-01-13
CN105050592B (zh) 2018-04-24
HK1212904A1 (en) 2016-06-24
SI2953621T1 (sl) 2019-07-31
ECSP15033898A (es) 2015-11-30
CA2900127C (en) 2021-02-09
KR20150112969A (ko) 2015-10-07
NZ709668A (en) 2020-06-26
PL2953621T3 (pl) 2019-09-30
EP2953621A1 (en) 2015-12-16

Similar Documents

Publication Publication Date Title
SV2017005461A (es) Benzamidas sustituidas con 1,3-tiazol-2-ilo
GT201500053A (es) Composicion farmaceutica recubierta que contiene regorafenib
PE20150200A1 (es) Formulacion de anticuerpos
CL2017000240A1 (es) Compuestos activos hacia bromodominios
AR090456A1 (es) Combinaciones farmaceuticas que comprenden un analogo de tionucleotidos
SV2015005115A (es) Derivados de la pirazolopirrolidina y su uso en el tratamiento de enfermedades
MX2015015500A (es) Composiciones de cenicriviroc y metodos para elaborarlas y usarlas.
CL2018000739A1 (es) Terapia adjuntiva con 25-hidroxi vitamina d y artículos de la misma.
CL2016000008A1 (es) Tratamiento de lesiones inflamatorias de rosacea con ivermectina.
PE20140255A1 (es) Tableta dispersable en forma oral
CO2018004206A2 (es) Formulación farmacéutica para administración oral que comprende un compuesto de 25-hidroxi vitamina d”
MX2015011316A (es) Imidazopiridazinas sustituidas.
MX2016008429A (es) Derivado de piranocromenil fenol, y composicion farmaceutica para tratar un sindrome metabolico o enfermedad inflamatoria.
AR085616A1 (es) Composicion farmaceutica inhalable que comprende glicopirrolato, uso
CO2017006898A2 (es) Formulación de relación fija de insulina glargina/lixisenatida
DOP2016000007A (es) Pirazolpiridinas sustituidas
MX2016015437A (es) Combinacion que comprende un glucocorticoide y edo-s101.
MX2017003780A (es) Composicion farmaceutica para tratar colitis ulcerativa.
AR091039A1 (es) Composiciones farmaceuticas topicas que comprenden terbinafina, uso y metodo de tratamiento
CL2016002879A1 (es) Composiciones farmacéuticas para tratar enfermedades infecciosas
PE20151300A1 (es) Composicion antifungica topica para el tratamiento de onicomicosis
UY35848A (es) Tienopirimidinas
MX2018007296A (es) Compuestos de isoindol.
CL2016002318A1 (es) Composición farmacéutica en forma de solución que comprende un portador líquido que comprende agua y entre 20% y 95% de uno o mas alcoholes y citrato de sildenafil disuelto en dicho portador líquido a una concentración de entre 7 y 125 mg/ml; métodos para obtenerla; forma de dosificación oral; forma de dosificación bucal; kits.
CL2015002627A1 (es) Composiciones para el uso en el tratamiento de trastornos oculares que usan dipiridamol

Legal Events

Date Code Title Description
FD Application declared void or lapsed