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PE20130045A1 - FORMULACIONES INTRAVENOSAS DE COENZIMA Q10 (CoQ10) Y METODOS DE USO DE LAS MISMAS - Google Patents

FORMULACIONES INTRAVENOSAS DE COENZIMA Q10 (CoQ10) Y METODOS DE USO DE LAS MISMAS

Info

Publication number
PE20130045A1
PE20130045A1 PE2012001544A PE2012001544A PE20130045A1 PE 20130045 A1 PE20130045 A1 PE 20130045A1 PE 2012001544 A PE2012001544 A PE 2012001544A PE 2012001544 A PE2012001544 A PE 2012001544A PE 20130045 A1 PE20130045 A1 PE 20130045A1
Authority
PE
Peru
Prior art keywords
amount
coq10
coenzyme
methods
same
Prior art date
Application number
PE2012001544A
Other languages
English (en)
Inventor
John Patrick Mccook
Niven Rajin Narain
Original Assignee
Berg Pharma Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44564137&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20130045(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Berg Pharma Llc filed Critical Berg Pharma Llc
Publication of PE20130045A1 publication Critical patent/PE20130045A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE REFIERE A UNA FORMULACION FARMACEUTICA QUE CONTIENE: A) UNA SOLUCION ACUOSA; B) UN AGENTE HIDROFOBICO ACTIVO TAL COMO COENZIMA Q10 (CoQ10) DISPERSADO EN UNA CANTIDAD DE 4% PARA FORMAR UNA NANO-DISPERSION COLOIDAL DE PARTICULAS TAL COMO UNA SUSPENSION O UNA EMULSION CUYO TAMANO MEDIO DE LAS PARTICULAS ES DE 10-NM A 200-NM; C) UN AGENTE ESTABILIZANTE DE DISPERSION TAL COMO DIMIRISTOILFOSFATIDIL COLINA (DMPC) EN UNA CANTIDAD DE 3%; D) UN REDUCTOR DE OPSONIZACION TAL COMO POLOXAMERO 188 EN UNA CANTIDAD DE 1.5%. TAMBIEN SE REFIERE A UN PROCEDIMIENTO DE PREPARACION. DICHA COMPOSICION ES DE ADMINISTRACION INTRAVENOSA SIENDO UTIL EN EL TRATAMIENTO DE CARCINOMA PANCREATICO, CANCER DE MAMA, MELANOMA, CANCER DE PULMON
PE2012001544A 2010-03-12 2011-03-11 FORMULACIONES INTRAVENOSAS DE COENZIMA Q10 (CoQ10) Y METODOS DE USO DE LAS MISMAS PE20130045A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31363210P 2010-03-12 2010-03-12
US38510710P 2010-09-21 2010-09-21

Publications (1)

Publication Number Publication Date
PE20130045A1 true PE20130045A1 (es) 2013-01-28

Family

ID=44564137

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2012001544A PE20130045A1 (es) 2010-03-12 2011-03-11 FORMULACIONES INTRAVENOSAS DE COENZIMA Q10 (CoQ10) Y METODOS DE USO DE LAS MISMAS

Country Status (27)

Country Link
US (2) US11400058B2 (es)
EP (2) EP3366280A1 (es)
JP (4) JP5968231B2 (es)
KR (2) KR102008658B1 (es)
CN (2) CN105168135A (es)
AU (4) AU2011224207B2 (es)
BR (1) BR112012022916B1 (es)
CA (2) CA2791693C (es)
CL (1) CL2012002507A1 (es)
CO (1) CO6620033A2 (es)
CR (1) CR20120507A (es)
CY (1) CY1120290T1 (es)
DK (1) DK2544663T3 (es)
EA (1) EA032941B1 (es)
ES (1) ES2664793T3 (es)
HK (1) HK1219055A1 (es)
IL (1) IL221675B (es)
MX (2) MX344078B (es)
MY (1) MY163995A (es)
NZ (3) NZ720022A (es)
PE (1) PE20130045A1 (es)
PH (1) PH12012501806B1 (es)
PL (1) PL2544663T3 (es)
PT (1) PT2544663T (es)
SG (3) SG10202010355PA (es)
TW (2) TWI610671B (es)
WO (1) WO2011112900A2 (es)

Families Citing this family (20)

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WO2010132507A2 (en) 2009-05-11 2010-11-18 Cytotech Labs, Llc Methods for treatment of disease using an epimetabolic shifter (coenzyme q10)
NZ720022A (en) 2010-03-12 2018-07-27 Berg Llc Intravenous formulations of coenzyme q10 (coq10) and methods of use thereof
ES2762451T3 (es) * 2011-04-04 2020-05-25 Berg Llc Tratamiento de tumores del sistema nervioso central con coenzima Q10
MY183615A (en) 2011-06-17 2021-03-03 Berg Llc Inhalable pharmaceutical compositions
NZ702369A (en) 2012-06-01 2016-12-23 Berg Llc Treatment of solid tumors using coenzyme q10
EP2983654B1 (en) * 2013-04-08 2025-11-12 BPGbio, Inc. Treatment of cancer using coenzyme q10 combination therapies
AU2014315186B2 (en) * 2013-09-04 2020-02-27 Berg Llc Methods of treatment of cancer by continuous infusion of coenzyme Q10
EA038458B1 (ru) * 2014-04-09 2021-08-31 Палс Фармасьютикалс Пвт. Лтд. Стабильная водная нанодисперсия водонерастворимых биоактивных соединений и способ ее получения
GB2544843B (en) * 2015-07-14 2022-08-03 Professional Compounding Centers Of America Pcca Poloxamer-based intralesional injections for the delivery of chemotherapeutic agents
US20170189350A1 (en) 2015-11-16 2017-07-06 Berg Llc Methods of treatment of temozolomide-resistant glioma using coenzyme q10
KR102682716B1 (ko) 2017-05-17 2024-07-08 비피지바이오, 인크. 수포성 표피박리증의 치료 및 예방에서 조효소 q10 제형의 용도
US12053441B2 (en) 2018-02-01 2024-08-06 The Royal Institution For The Advancement Of Learning/Mcgill University Formulations for improving the delivery of hydrophobic agents
KR20200141080A (ko) * 2018-04-09 2020-12-17 오르제네시스 인코포레이티드 바이옥솜 입자, 레독솜, 방법 및 조성물
WO2020081601A1 (en) * 2018-10-15 2020-04-23 Berg Llc Methods of treating pancreatic cancer using coenzyme q10
IL268457B (en) * 2019-08-04 2022-05-01 Omega 3 Galilee Ltd Oil- suspension of edible solids and methods of preparing the same
US20210322339A1 (en) 2019-11-20 2021-10-21 Berg Llc Combination therapy of coenzyme q10 and radiation for treatment of glioma
JPWO2023120553A1 (es) * 2021-12-24 2023-06-29
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