[go: up one dir, main page]

WO2013104892A8 - Application of high dose compounds via inhalation - Google Patents

Application of high dose compounds via inhalation Download PDF

Info

Publication number
WO2013104892A8
WO2013104892A8 PCT/GB2013/000015 GB2013000015W WO2013104892A8 WO 2013104892 A8 WO2013104892 A8 WO 2013104892A8 GB 2013000015 W GB2013000015 W GB 2013000015W WO 2013104892 A8 WO2013104892 A8 WO 2013104892A8
Authority
WO
WIPO (PCT)
Prior art keywords
application
via inhalation
compounds via
high dose
dose compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2013/000015
Other languages
French (fr)
Other versions
WO2013104892A1 (en
Inventor
Pedro Mendes
Ana GONÇALVES
Isabel Sequeira Lopes
Jason SUGGETT
Phillip Nelson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hovione Inter AG
Original Assignee
Hovione Inter AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hovione Inter AG filed Critical Hovione Inter AG
Publication of WO2013104892A1 publication Critical patent/WO2013104892A1/en
Publication of WO2013104892A8 publication Critical patent/WO2013104892A8/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

This invention concerns the delivery of high doses of active pharmaceutical compounds via inhalation. A pharmaceutical formulation in the form of a powder suitable for inhalation comprises one or more active pharmaceutical ingredients and a mucolytic agent and/or a buffer, wherein the formulation is free of carrier.
PCT/GB2013/000015 2012-01-13 2013-01-14 Application of high dose compounds via inhalation Ceased WO2013104892A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PT106094A PT106094A (en) 2012-01-13 2012-01-13 ADMINISTRATION BY INHALATION OF FORMULATIONS WITH HIGH DOSE
PT106094 2012-01-13

Publications (2)

Publication Number Publication Date
WO2013104892A1 WO2013104892A1 (en) 2013-07-18
WO2013104892A8 true WO2013104892A8 (en) 2013-09-19

Family

ID=47605587

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2013/000015 Ceased WO2013104892A1 (en) 2012-01-13 2013-01-14 Application of high dose compounds via inhalation

Country Status (2)

Country Link
PT (1) PT106094A (en)
WO (1) WO2013104892A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2410981T (en) 2009-03-26 2017-05-25 Pulmatrix Inc Dry powder formulations and methods for treating pulmonary diseases
AU2011296343B2 (en) 2010-08-30 2015-12-10 Pulmatrix Operating Company, Inc. Dry powder formulations and methods for treating pulmonary diseases
CA3086367A1 (en) 2010-09-29 2012-04-05 Pulmatrix Operating Company, Inc. Monovalent metal cation dry powders for inhalation
PT2621488T (en) 2010-09-29 2019-02-12 Pulmatrix Operating Co Inc Cationic dry powders
CN104487075A (en) 2012-02-29 2015-04-01 普马特里克斯公司 respirable dry powder
AU2014248455B2 (en) 2013-04-01 2018-12-06 Pulmatrix Operating Company, Inc. Tiotropium dry powders
SG11201700621XA (en) 2014-07-25 2017-02-27 Agency Science Tech & Res Antibiotic compositions for treating bacterial infections
CN114796168A (en) * 2017-11-08 2022-07-29 北京盈科瑞创新药物研究有限公司 Carbocisteine aerosol inhalation solution preparation and preparation method thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1242211A (en) 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Pharmaceutical composition
US20030113273A1 (en) * 1996-06-17 2003-06-19 Patton John S. Methods and compositions for pulmonary delivery of insulin
US6858199B1 (en) 2000-06-09 2005-02-22 Advanced Inhalation Research, Inc. High efficient delivery of a large therapeutic mass aerosol
PL2486942T3 (en) * 2004-11-24 2019-05-31 Meda Pharmaceuticals Inc Compositions comprising azelastine and methods of use thereof
US8758816B2 (en) * 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
US20070123449A1 (en) * 2005-11-01 2007-05-31 Advanced Inhalation Research, Inc. High load particles for inhalation having rapid release properties
WO2007061454A1 (en) * 2005-11-22 2007-05-31 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
US20090098207A1 (en) * 2007-07-24 2009-04-16 Nexbio, Inc. Technology for the Preparation of Microparticles
US20120083531A1 (en) * 2009-03-26 2012-04-05 Clarke Robert W Calcium citrate and calcium lactate formulations for alteration of biophysical properties of mucosal lining
PT105065B (en) * 2010-04-26 2012-07-31 Hovione Farmaciencia S A A SIMPLE INHALER OF CAPSULES
GB201021186D0 (en) 2010-12-14 2011-01-26 Novabiotics Ltd Composition

Also Published As

Publication number Publication date
WO2013104892A1 (en) 2013-07-18
PT106094A (en) 2013-07-15

Similar Documents

Publication Publication Date Title
WO2013104892A8 (en) Application of high dose compounds via inhalation
PH12014502778A1 (en) Antibody formulation
WO2015054124A3 (en) Dry powder inhaler
HK1221653A1 (en) Compositions, methods & systems for respiratory delivery of three or more active agents
EA201590805A1 (en) COMPOSITION WITH IMMEDIATE AND PROLONGED DELIVERY
MY165888A (en) Dry powder formulation comprising a corticosteroid and a beta-adrenergic for administration by inhalation
MX2015015132A (en) Inhalable pharmaceutical compositions and the inhaler devices containing them.
MX370890B (en) Composition comprising salbutamol sulphate.
WO2014028796A3 (en) Preparation of liposome compressible delivery systems
MX2015005762A (en) Co-micronisation product comprising ulipristal acetate.
WO2014007772A3 (en) Inhalation compositions comprising glucose anhydrous
MX2014002780A (en) Pharmaceutical compositions comprising an aromatase inhibitor.
WO2014007770A3 (en) Inhalation compositions comprising corticosteroid and sorbitol
PH12014502619A1 (en) Novel dosage and formulation
WO2014007781A3 (en) Inhalation compositions
MX2016001422A (en) Pharmaceutical compositions of fingolimod.
MX2018010065A (en) Oral dosage form comprising rifaximin in form beta.
MX2015015150A (en) Inhalable pharmaceutical compositions and the inhaler devices containing them.
MX2015009891A (en) Pharmaceutical compositions comprising multi-component crystalline particles suitable for use in inhalation therapy.
MX2017013634A (en) FIXED DOSE COMBINATION RESISTANT TO HANDLING THAT PROVIDES A QUICK RELEASE OF TWO DRUGS FROM PARTICLES AND A POWDER.
LV15003A (en) A pharmaceutical composition for the control of weight gain
PH12015501179A1 (en) Fixed dose pharmaceutical composition comprising mometasone and azelastine
WO2013127539A3 (en) Pharmaceutical formulation containing flupirtin
PT2617451T (en) Drug delivery assembly, and single dose inhaler for dry powder drug delivery having such assembly
IN2013MU03567A (en)

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 13701499

Country of ref document: EP

Kind code of ref document: A1

DPE1 Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101)
NENP Non-entry into the national phase in:

Ref country code: DE

122 Ep: pct app. not ent. europ. phase

Ref document number: 13701499

Country of ref document: EP

Kind code of ref document: A1