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WO2013104892A8 - Application de composés à fortes doses par inhalation - Google Patents

Application de composés à fortes doses par inhalation Download PDF

Info

Publication number
WO2013104892A8
WO2013104892A8 PCT/GB2013/000015 GB2013000015W WO2013104892A8 WO 2013104892 A8 WO2013104892 A8 WO 2013104892A8 GB 2013000015 W GB2013000015 W GB 2013000015W WO 2013104892 A8 WO2013104892 A8 WO 2013104892A8
Authority
WO
WIPO (PCT)
Prior art keywords
application
via inhalation
compounds via
high dose
dose compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2013/000015
Other languages
English (en)
Other versions
WO2013104892A1 (fr
Inventor
Pedro Mendes
Ana GONÇALVES
Isabel Sequeira Lopes
Jason SUGGETT
Phillip Nelson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hovione Inter AG
Original Assignee
Hovione Inter AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hovione Inter AG filed Critical Hovione Inter AG
Publication of WO2013104892A1 publication Critical patent/WO2013104892A1/fr
Publication of WO2013104892A8 publication Critical patent/WO2013104892A8/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Cette invention concerne l'administration de fortes doses de principes pharmaceutiquement actifs par inhalation. Une formulation pharmaceutique sous la forme d'une poudre se prêtant à l'inhalation qui comprend un ou plusieurs principes pharmaceutiquement actifs et un agent mucolytique et/ou un tampon, ladite formulation étant dépourvue de véhicule, est décrite.
PCT/GB2013/000015 2012-01-13 2013-01-14 Application de composés à fortes doses par inhalation Ceased WO2013104892A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PT106094A PT106094A (pt) 2012-01-13 2012-01-13 Administração por inalação de formulações com dose elevada
PT106094 2012-01-13

Publications (2)

Publication Number Publication Date
WO2013104892A1 WO2013104892A1 (fr) 2013-07-18
WO2013104892A8 true WO2013104892A8 (fr) 2013-09-19

Family

ID=47605587

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2013/000015 Ceased WO2013104892A1 (fr) 2012-01-13 2013-01-14 Application de composés à fortes doses par inhalation

Country Status (2)

Country Link
PT (1) PT106094A (fr)
WO (1) WO2013104892A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2410981T (pt) 2009-03-26 2017-05-25 Pulmatrix Inc Formulações em pó seco e métodos para tratar doenças pulmonares
AU2011296343B2 (en) 2010-08-30 2015-12-10 Pulmatrix Operating Company, Inc. Dry powder formulations and methods for treating pulmonary diseases
CA3086367A1 (fr) 2010-09-29 2012-04-05 Pulmatrix Operating Company, Inc. Poudres seches a cations metalliques monovalents pour inhalation
PT2621488T (pt) 2010-09-29 2019-02-12 Pulmatrix Operating Co Inc Pós secos catiónicos
CN104487075A (zh) 2012-02-29 2015-04-01 普马特里克斯公司 可吸入干粉剂
AU2014248455B2 (en) 2013-04-01 2018-12-06 Pulmatrix Operating Company, Inc. Tiotropium dry powders
SG11201700621XA (en) 2014-07-25 2017-02-27 Agency Science Tech & Res Antibiotic compositions for treating bacterial infections
CN114796168A (zh) * 2017-11-08 2022-07-29 北京盈科瑞创新药物研究有限公司 一种羧甲司坦雾化吸入用溶液制剂及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1242211A (en) 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Pharmaceutical composition
US20030113273A1 (en) * 1996-06-17 2003-06-19 Patton John S. Methods and compositions for pulmonary delivery of insulin
US6858199B1 (en) 2000-06-09 2005-02-22 Advanced Inhalation Research, Inc. High efficient delivery of a large therapeutic mass aerosol
PL2486942T3 (pl) * 2004-11-24 2019-05-31 Meda Pharmaceuticals Inc Kompozycje zawierające azelastynę oraz sposoby ich stosowania
US8758816B2 (en) * 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
US20070123449A1 (en) * 2005-11-01 2007-05-31 Advanced Inhalation Research, Inc. High load particles for inhalation having rapid release properties
WO2007061454A1 (fr) * 2005-11-22 2007-05-31 Medpointe Healthcare Inc. Compositions comprenant de l'azelastine et procedes d'utilisation de celles-ci
US20090098207A1 (en) * 2007-07-24 2009-04-16 Nexbio, Inc. Technology for the Preparation of Microparticles
US20120083531A1 (en) * 2009-03-26 2012-04-05 Clarke Robert W Calcium citrate and calcium lactate formulations for alteration of biophysical properties of mucosal lining
PT105065B (pt) * 2010-04-26 2012-07-31 Hovione Farmaciencia S A Um inalador simples de cápsulas
GB201021186D0 (en) 2010-12-14 2011-01-26 Novabiotics Ltd Composition

Also Published As

Publication number Publication date
WO2013104892A1 (fr) 2013-07-18
PT106094A (pt) 2013-07-15

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