PE20000702A1 - Formulaciones intranasales para tratar trastornos sexuales - Google Patents
Formulaciones intranasales para tratar trastornos sexualesInfo
- Publication number
- PE20000702A1 PE20000702A1 PE1999000543A PE00054399A PE20000702A1 PE 20000702 A1 PE20000702 A1 PE 20000702A1 PE 1999000543 A PE1999000543 A PE 1999000543A PE 00054399 A PE00054399 A PE 00054399A PE 20000702 A1 PE20000702 A1 PE 20000702A1
- Authority
- PE
- Peru
- Prior art keywords
- sexual disorders
- intranasal formulations
- formulation
- micrometers
- aqueous solution
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gynecology & Obstetrics (AREA)
- Otolaryngology (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE REFIERE A FORMULACIONES INTRANASALES EN SOLUCION ACUOSA O EN POLVO QUE COMPRENDEN a)UN INHIBIDOR DE LA GUANOSINA 3`,5'-MONOFOSFATO CICLICO FOSFODIESTERASA TIPO 5 (cGMP PDE5) TAL COMO MESILATO DE SILDENAFIL; b)UN DILUYENTE TAL COMO GLICEROL ACUOSO 5% (P/V); c)ADICIONALMENTE PUEDE COMPRENDER CAFEINA; LA FORMULACION SE CARACTERIZA POR UN TAMANO DE PARTICULA DE 5 MICROMETROS A 40 MICROMETROS. UNA FORMULACION PREFERIDA COMPRENDE 100 mg/ml DE MESILATO DE SILDENAFILO, 15 mg/ml DE CAFEINA EN SOLUCION ACUOSA TAMPONADA A UN pH DE 4,2. LA FORMULACION PUEDE SER UTIL PARA EL TRATAMIENTO DE LA DISFUNCION ERECTIL MASCULINA (IMPOTENCIA), TRASTORNOS SEXUALES FEMENINOS
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9813452.1A GB9813452D0 (en) | 1998-06-22 | 1998-06-22 | Pharmaceutical formulations |
| GBGB9820837.4A GB9820837D0 (en) | 1998-09-24 | 1998-09-24 | Pharmaceutical formulations |
| GBGB9903177.5A GB9903177D0 (en) | 1999-02-13 | 1999-02-13 | Pharmaceutical formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20000702A1 true PE20000702A1 (es) | 2000-08-16 |
Family
ID=27269368
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1999000543A PE20000702A1 (es) | 1998-06-22 | 1999-06-18 | Formulaciones intranasales para tratar trastornos sexuales |
Country Status (40)
| Country | Link |
|---|---|
| US (2) | US20020040139A1 (es) |
| EP (1) | EP0967214B1 (es) |
| JP (1) | JP3263379B2 (es) |
| KR (1) | KR100345824B1 (es) |
| AP (1) | AP1178A (es) |
| AR (1) | AR016993A1 (es) |
| AT (1) | ATE269866T1 (es) |
| AU (1) | AU746865B2 (es) |
| BG (1) | BG64372B1 (es) |
| BR (1) | BR9903273A (es) |
| CA (1) | CA2275554C (es) |
| CZ (1) | CZ294856B6 (es) |
| DE (1) | DE69918222T2 (es) |
| DK (1) | DK0967214T3 (es) |
| DZ (1) | DZ2826A1 (es) |
| EA (1) | EA001903B1 (es) |
| ES (1) | ES2221733T3 (es) |
| GT (1) | GT199900095A (es) |
| HN (1) | HN1999000096A (es) |
| HR (1) | HRP990195B1 (es) |
| HU (1) | HUP9902076A3 (es) |
| ID (1) | ID23554A (es) |
| IL (1) | IL130539A0 (es) |
| IS (1) | IS5085A (es) |
| MA (1) | MA25089A1 (es) |
| MY (1) | MY117967A (es) |
| NO (1) | NO317365B1 (es) |
| NZ (1) | NZ336382A (es) |
| OA (1) | OA11069A (es) |
| PA (1) | PA8476301A1 (es) |
| PE (1) | PE20000702A1 (es) |
| PT (1) | PT967214E (es) |
| SG (1) | SG77246A1 (es) |
| SI (1) | SI0967214T1 (es) |
| SK (1) | SK284574B6 (es) |
| TN (1) | TNSN99129A1 (es) |
| TR (1) | TR199901444A2 (es) |
| TW (1) | TWI223598B (es) |
| UA (1) | UA59385C2 (es) |
| YU (1) | YU29699A (es) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6200591B1 (en) | 1998-06-25 | 2001-03-13 | Anwar A. Hussain | Method of administration of sildenafil to produce instantaneous response for the treatment of erectile dysfunction |
| GB9828340D0 (en) * | 1998-12-22 | 1999-02-17 | Novartis Ag | Organic compounds |
| EP1237538A2 (en) * | 1999-11-18 | 2002-09-11 | Natco Pharma Limited | An improved pharmaceutical composition for treating male erectile dysfunction |
| KR20010016165A (ko) * | 2000-11-16 | 2001-03-05 | 정순학 | 성기능 장애 치료를 위한 피부에 적용하는 제제 |
| DE10118306A1 (de) * | 2001-04-12 | 2002-10-17 | Bayer Ag | Imidazotriazinonhaltige Zusammensetzungen zur nasalen Applikation |
| DE10118305A1 (de) * | 2001-04-12 | 2002-10-17 | Bayer Ag | Zusammensetzungen zur nasalen Applikation |
| US20070122353A1 (en) | 2001-05-24 | 2007-05-31 | Hale Ron L | Drug condensation aerosols and kits |
| AU2002310086B2 (en) * | 2001-05-24 | 2008-09-04 | Alexza Pharmaceuticals, Inc. | Delivery of erectile dysfunction drugs through an inhalation route |
| CA2446904A1 (en) | 2001-05-24 | 2003-04-03 | Alexza Molecular Delivery Corporation | Delivery of drug esters through an inhalation route |
| US7585493B2 (en) | 2001-05-24 | 2009-09-08 | Alexza Pharmaceuticals, Inc. | Thin-film drug delivery article and method of use |
| US7766013B2 (en) | 2001-06-05 | 2010-08-03 | Alexza Pharmaceuticals, Inc. | Aerosol generating method and device |
| US7458374B2 (en) | 2002-05-13 | 2008-12-02 | Alexza Pharmaceuticals, Inc. | Method and apparatus for vaporizing a compound |
| US7645442B2 (en) | 2001-05-24 | 2010-01-12 | Alexza Pharmaceuticals, Inc. | Rapid-heating drug delivery article and method of use |
| US7090830B2 (en) | 2001-05-24 | 2006-08-15 | Alexza Pharmaceuticals, Inc. | Drug condensation aerosols and kits |
| DE10248601B4 (de) * | 2002-10-17 | 2006-05-24 | Goldstein, Naum, Dr.habil.nat. | Pharmazeutisches Mittel zur endonasalen Applikation bei der Behandlung von Krankheiten und Störungen des zentralen Nervensystems |
| US20040105818A1 (en) | 2002-11-26 | 2004-06-03 | Alexza Molecular Delivery Corporation | Diuretic aerosols and methods of making and using them |
| US7913688B2 (en) | 2002-11-27 | 2011-03-29 | Alexza Pharmaceuticals, Inc. | Inhalation device for producing a drug aerosol |
| US7138107B2 (en) * | 2003-02-18 | 2006-11-21 | Compellis Pharmaceuticals | Inhibition of olfactory neurosensory function to treat eating disorders and obesity |
| US7638138B2 (en) | 2003-02-21 | 2009-12-29 | Translational Research, Ltd. | Compositions for nasal administration of pharmaceuticals |
| US7278982B2 (en) | 2003-03-27 | 2007-10-09 | Bioactis Limited | Powder medicine applicator for nasal cavity |
| AR043880A1 (es) * | 2003-04-22 | 2005-08-17 | Solvay Pharm Gmbh | Mesilato acido de 4-(4.trans-hidroxiciclohexil) amino-2-fenil-7h-pirrolo (2,3-d) pirimidina y sus formas polimorfas |
| JP2007516404A (ja) | 2003-05-21 | 2007-06-21 | アレックザ ファーマシューティカルズ， インコーポレイテッド | 光学点火されたかまたは電気点火された内蔵式加熱ユニットおよびそれを使用する薬剤供給ユニット |
| US7540286B2 (en) | 2004-06-03 | 2009-06-02 | Alexza Pharmaceuticals, Inc. | Multiple dose condensation aerosol devices and methods of forming condensation aerosols |
| WO2006016530A1 (ja) * | 2004-08-10 | 2006-02-16 | Translational Research, Ltd. | 速効性でかつ高い吸収性を可能とする経鼻投与用組成物 |
| EP2246086A3 (en) | 2004-08-12 | 2012-11-21 | Alexza Pharmaceuticals, Inc. | Aerosol drug delivery device incorporating percussively activated heating unit |
| US20060046962A1 (en) * | 2004-08-25 | 2006-03-02 | Aegis Therapeutics Llc | Absorption enhancers for drug administration |
| US8268791B2 (en) * | 2004-08-25 | 2012-09-18 | Aegis Therapeutics, Llc. | Alkylglycoside compositions for drug administration |
| US20140162965A1 (en) | 2004-08-25 | 2014-06-12 | Aegis Therapeutics, Inc. | Compositions for oral drug administration |
| US20090047347A1 (en) * | 2005-07-29 | 2009-02-19 | Aegis Therapeutics, Inc. | Compositions for Drug Administration |
| US9895444B2 (en) | 2004-08-25 | 2018-02-20 | Aegis Therapeutics, Llc | Compositions for drug administration |
| KR101289917B1 (ko) | 2004-10-18 | 2013-07-25 | 폴리문 사이언티픽 임무노이비오로기쉐 포르슝 게엠베하 | 평활근을 이완시키기 위한 활성 성분을 함유하는 리포좀조성물, 이런 조성물의 생산 및 이의 치료적 용도 |
| JP2008532973A (ja) * | 2005-03-09 | 2008-08-21 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 抗コリン作用薬とｐｄｅ５−阻害剤に基づく新規な医薬組成物 |
| EP2366393B1 (en) | 2005-04-19 | 2013-08-07 | Takeda GmbH | Roflumilast for the treatment of pulmonary hypertension |
| US8506934B2 (en) | 2005-04-29 | 2013-08-13 | Robert I. Henkin | Methods for detection of biological substances |
| WO2007027612A2 (en) * | 2005-08-29 | 2007-03-08 | Teva Pharmaceutical Industries Ltd. | Solid particulate tadalafil having a bimodal particle size distribution |
| GB0526283D0 (en) * | 2005-12-23 | 2006-02-01 | Givaudan Sa | Compositions |
| GB0606234D0 (en) * | 2006-03-29 | 2006-05-10 | Pliva Istrazivanje I Razvoj D | Pharmaceutically acceptable salts and polymorphic forms |
| US8226949B2 (en) | 2006-06-23 | 2012-07-24 | Aegis Therapeutics Llc | Stabilizing alkylglycoside compositions and methods thereof |
| CN101668544B (zh) * | 2006-12-26 | 2013-04-24 | 株式会社新日本科学 | 经鼻投用制剂 |
| US8293489B2 (en) | 2007-01-31 | 2012-10-23 | Henkin Robert I | Methods for detection of biological substances |
| EP2121088B1 (en) | 2007-03-09 | 2016-07-13 | Alexza Pharmaceuticals, Inc. | Heating unit for use in a drug delivery device |
| DE102008004893A1 (de) | 2008-01-17 | 2009-07-23 | Add Technologies Ltd. | Trägerpellets, Verfahren zu deren Herstellung und deren Verwendung |
| US20110033506A1 (en) * | 2008-02-08 | 2011-02-10 | Adel Penhasi | Combination dosage form of low-dose modafinil and low-dose sildenafil |
| AU2009228093B2 (en) | 2008-03-28 | 2014-08-07 | Neurelis, Inc. | Administration of benzodiazepine compositions |
| WO2009148442A1 (en) | 2008-06-04 | 2009-12-10 | Colgate-Palmolive Company | Oral care implement with cavitation system |
| WO2009152344A2 (en) * | 2008-06-11 | 2009-12-17 | Comgenrx, Inc. | Combination therapy using phosphodiesterase inhibitors |
| US8580801B2 (en) | 2008-07-23 | 2013-11-12 | Robert I. Henkin | Phosphodiesterase inhibitor treatment |
| US8440631B2 (en) | 2008-12-22 | 2013-05-14 | Aegis Therapeutics, Llc | Compositions for drug administration |
| JP2012526726A (ja) * | 2009-05-15 | 2012-11-01 | 株式会社新日本科学 | 薬物動態が改善された鼻腔内用薬学的組成物 |
| JP2011001317A (ja) * | 2009-06-19 | 2011-01-06 | Fumakilla Ltd | 鼻用洗浄剤 |
| US8827946B2 (en) * | 2009-07-31 | 2014-09-09 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal granisetron and nasal applicator |
| MX340188B (es) | 2010-05-10 | 2016-06-30 | Euro-Celtique S A * | Elaboracion de granulos sin activos y tabletas que comprenden los mismos. |
| JP5840201B2 (ja) | 2010-05-10 | 2016-01-06 | ユーロ−セルティーク エス．エイ． | 活性剤を負荷した顆粒と追加の活性剤の組合せ |
| PT3415139T (pt) | 2011-06-14 | 2022-06-20 | Neurelis Inc | Administração de benzodiazepina |
| CN102952138B (zh) * | 2011-08-17 | 2016-07-06 | 上海特化医药科技有限公司 | 一种吡唑并嘧啶酮化合物的盐、多晶型物及其药物组合物、制备方法和应用 |
| GB2497933B (en) * | 2011-12-21 | 2014-12-24 | Londonpharma Ltd | Drug delivery technology |
| EP2903619B1 (en) * | 2012-10-05 | 2019-06-05 | Robert I. Henkin | Phosphodiesterase inhibitors for treating taste and smell disorders |
| CA2881144A1 (en) * | 2012-11-09 | 2014-05-09 | Purdue Pharma | Pharmaceutical compositions comprising hydromorphone and naloxone |
| RU2536425C2 (ru) * | 2013-01-17 | 2014-12-20 | Общество с ограниченной ответственностью "Фармамед" | Фармацевтическая композиция, содержащая силденафил цитрат, и способ ее приготовления |
| WO2014143453A1 (en) * | 2013-03-15 | 2014-09-18 | Henkin Robert I | Phosphodiesterase inhibitor treatment |
| NZ719087A (en) | 2013-11-13 | 2017-12-22 | Euro Celtique Sa | Hydromorphone and naloxone for treatment of pain and opioid bowel dysfunction syndrome |
| CN106233141B (zh) | 2014-02-18 | 2018-08-21 | 罗伯特·I·汉金 | 用于诊断和治疗味觉或嗅觉的损失和/或失真的方法和组合物 |
| NO2723977T3 (es) | 2014-03-19 | 2018-03-10 | ||
| EP3331888A4 (en) * | 2015-08-03 | 2019-03-20 | Synergistic Therapeutics, LLC | THERAPEUTIC GEL FOR SEXUAL DYSFUNCTION |
| EP3532068A4 (en) * | 2016-10-31 | 2020-04-29 | Suda Ltd | ADMINISTRATION OF ACTIVE INGREDIENTS BY MUCOSA |
| CN110603033A (zh) * | 2017-03-02 | 2019-12-20 | 荷兰可再生能源公司 | 生理活性物质的鼻内给药 |
| US11744967B2 (en) | 2017-09-26 | 2023-09-05 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal delivery devices |
| CA3086881A1 (en) * | 2017-12-26 | 2019-07-04 | Ftf Pharma Private Limited | Liquid oral formulations for pde v inhibitors |
| KR102852740B1 (ko) | 2018-02-02 | 2025-08-29 | 알렉스자 파마스티칼즈, 인크. | 전기적 응축 에어로졸 디바이스 |
| WO2019157099A1 (en) | 2018-02-06 | 2019-08-15 | Aegis Therapeutics, Llc | Intranasal epinephrine formulations and methods for the treatment of disease |
| EP3781191A4 (en) * | 2018-04-16 | 2022-01-19 | Barista Mist Pty Ltd | CAFFEINE COMPOSITIONS AND METHODS OF USE |
| SE542968C2 (en) * | 2018-10-26 | 2020-09-22 | Lindahl Anders | Treatment of osteoarthritis |
| WO2022026762A1 (en) * | 2020-07-29 | 2022-02-03 | Lido Ventures Llc | Apparatus, system, and method for facilitating intranasal treatment of a patient |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5250534A (en) * | 1990-06-20 | 1993-10-05 | Pfizer Inc. | Pyrazolopyrimidinone antianginal agents |
| GB9311920D0 (en) * | 1993-06-09 | 1993-07-28 | Pfizer Ltd | Therapeutic agents |
| US5565466A (en) * | 1993-08-13 | 1996-10-15 | Zonagen, Inc. | Methods for modulating the human sexual response |
| EA000967B1 (ru) * | 1995-11-20 | 2000-08-28 | Эли Лилли Энд Компани | Ингибитор протеинкиназы c |
| AU739417B2 (en) * | 1997-05-29 | 2001-10-11 | Mochida Pharmaceutical Co., Ltd. | Therapeutic agent for erection dysfunction |
| WO1999027905A1 (en) * | 1997-12-02 | 1999-06-10 | West Pharmaceutical Services Drug Delivery & Clinical Research Centre Limited | Compositions for nasal administration |
| US6087368A (en) * | 1998-06-08 | 2000-07-11 | Bristol-Myers Squibb Company | Quinazolinone inhibitors of cGMP phosphodiesterase |
-
1999
- 1999-05-29 TW TW088108934A patent/TWI223598B/zh active
- 1999-06-08 ES ES99304425T patent/ES2221733T3/es not_active Expired - Lifetime
- 1999-06-08 SI SI9930594T patent/SI0967214T1/xx unknown
- 1999-06-08 AT AT99304425T patent/ATE269866T1/de not_active IP Right Cessation
- 1999-06-08 DK DK99304425T patent/DK0967214T3/da active
- 1999-06-08 PT PT99304425T patent/PT967214E/pt unknown
- 1999-06-08 DE DE69918222T patent/DE69918222T2/de not_active Expired - Fee Related
- 1999-06-08 EP EP99304425A patent/EP0967214B1/en not_active Expired - Lifetime
- 1999-06-15 HN HN1999000096A patent/HN1999000096A/es unknown
- 1999-06-17 AP APAP/P/1999/001585A patent/AP1178A/en active
- 1999-06-17 SG SG1999002935A patent/SG77246A1/en unknown
- 1999-06-17 SK SK819-99A patent/SK284574B6/sk unknown
- 1999-06-17 IL IL13053999A patent/IL130539A0/xx unknown
- 1999-06-18 AR ARP990102946A patent/AR016993A1/es unknown
- 1999-06-18 US US09/335,628 patent/US20020040139A1/en not_active Abandoned
- 1999-06-18 MY MYPI99002521A patent/MY117967A/en unknown
- 1999-06-18 OA OA9900137A patent/OA11069A/en unknown
- 1999-06-18 IS IS5085A patent/IS5085A/is unknown
- 1999-06-18 HR HR990195A patent/HRP990195B1/xx not_active IP Right Cessation
- 1999-06-18 PE PE1999000543A patent/PE20000702A1/es not_active Application Discontinuation
- 1999-06-18 CA CA002275554A patent/CA2275554C/en not_active Expired - Fee Related
- 1999-06-21 PA PA19998476301A patent/PA8476301A1/es unknown
- 1999-06-21 JP JP17392599A patent/JP3263379B2/ja not_active Expired - Fee Related
- 1999-06-21 UA UA99063463A patent/UA59385C2/uk unknown
- 1999-06-21 EA EA199900487A patent/EA001903B1/ru not_active IP Right Cessation
- 1999-06-21 AU AU35794/99A patent/AU746865B2/en not_active Ceased
- 1999-06-21 ID IDP990592D patent/ID23554A/id unknown
- 1999-06-21 HU HU9902076A patent/HUP9902076A3/hu unknown
- 1999-06-21 TN TNTNSN99129A patent/TNSN99129A1/fr unknown
- 1999-06-21 NZ NZ336382A patent/NZ336382A/xx unknown
- 1999-06-21 CZ CZ19992257A patent/CZ294856B6/cs not_active IP Right Cessation
- 1999-06-21 MA MA25639A patent/MA25089A1/fr unknown
- 1999-06-21 NO NO19993051A patent/NO317365B1/no unknown
- 1999-06-21 BG BG103510A patent/BG64372B1/bg unknown
- 1999-06-21 KR KR1019990023169A patent/KR100345824B1/ko not_active Expired - Fee Related
- 1999-06-21 DZ DZ990126A patent/DZ2826A1/xx active
- 1999-06-22 BR BR9903273-2A patent/BR9903273A/pt not_active IP Right Cessation
- 1999-06-22 TR TR1999/01444A patent/TR199901444A2/xx unknown
- 1999-06-22 YU YU29699A patent/YU29699A/sh unknown
- 1999-06-22 GT GT199900095A patent/GT199900095A/es unknown
-
2003
- 2003-03-14 US US10/389,127 patent/US20030158206A1/en not_active Abandoned
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| FG | Grant, registration | ||
| FD | Application declared void or lapsed |