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PE20000632A1 - Formulaciones de ziprasidona - Google Patents

Formulaciones de ziprasidona

Info

Publication number
PE20000632A1
PE20000632A1 PE1999000523A PE00052399A PE20000632A1 PE 20000632 A1 PE20000632 A1 PE 20000632A1 PE 1999000523 A PE1999000523 A PE 1999000523A PE 00052399 A PE00052399 A PE 00052399A PE 20000632 A1 PE20000632 A1 PE 20000632A1
Authority
PE
Peru
Prior art keywords
ziprasidone
auc
refers
composition
particle size
Prior art date
Application number
PE1999000523A
Other languages
English (en)
Inventor
Frank Robert Busch
Angela Carol Gatlin Hausberger
Daniel Ray Arenson
Bijan Rasadi
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22216447&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20000632(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of PE20000632A1 publication Critical patent/PE20000632A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Detergent Compositions (AREA)
  • Feeding Of Articles By Means Other Than Belts Or Rollers (AREA)
  • Polyamides (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

SE REFIERE A UNA COMPOSICION QUE COMPRENDE PARTICULAS DE LA BASE O HIDROCLORURO DE ZIPRASIDONA CRISTALINA DE PREFERENCIA MONOHIDRATADO, QUE SE CARACTERIZA POR UN TAMANO MEDIO DE PARTICULAS IGUAL O MENOR DE 85µm, EXHIBE UNA AUC O CONCENTRACION MAXIMA DE POR LO MENOS EL 80% DE LA AUC O LA CONCENTRACION MAXIMA MEDIA OBSERVADA EN UNA FORMULACION DE HIDROCLORURO DE ZIPRASIDONA CON UN TAMANO DE PARTICULAS DE 20 µm. TAMBIEN SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION. LA COMPOSICION PUEDE SER UTIL PARA EL TRATAMIENTO DE PSICOSIS, ESQUIZOFRENIA
PE1999000523A 1998-06-15 1999-06-11 Formulaciones de ziprasidona PE20000632A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8922998P 1998-06-15 1998-06-15

Publications (1)

Publication Number Publication Date
PE20000632A1 true PE20000632A1 (es) 2000-07-26

Family

ID=22216447

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1999000523A PE20000632A1 (es) 1998-06-15 1999-06-11 Formulaciones de ziprasidona

Country Status (44)

Country Link
US (1) US6150366A (es)
EP (1) EP0965343B1 (es)
JP (2) JP3441676B2 (es)
KR (1) KR100338915B1 (es)
CN (1) CN1307994C (es)
AP (1) AP1216A (es)
AR (1) AR015553A1 (es)
AT (1) ATE240732T1 (es)
AU (1) AU753820B2 (es)
BG (1) BG64691B1 (es)
BR (1) BR9902268A (es)
CA (1) CA2274338C (es)
CO (1) CO5070579A1 (es)
CY (1) CY2003002I1 (es)
CZ (1) CZ297954B6 (es)
DE (1) DE69908021T2 (es)
DK (1) DK0965343T3 (es)
EA (1) EA002223B1 (es)
ES (1) ES2197581T3 (es)
GT (1) GT199900080A (es)
HN (1) HN1999000089A (es)
HR (1) HRP990193B1 (es)
HU (1) HU226487B1 (es)
ID (1) ID23546A (es)
IL (1) IL130424A (es)
IS (1) IS2182B (es)
MA (1) MA26647A1 (es)
MY (1) MY121397A (es)
NO (1) NO316713B1 (es)
NZ (1) NZ336271A (es)
OA (1) OA11064A (es)
PA (1) PA8475601A1 (es)
PE (1) PE20000632A1 (es)
PL (2) PL195209B1 (es)
PT (1) PT965343E (es)
RS (1) RS49611B (es)
SG (1) SG77243A1 (es)
SI (1) SI0965343T1 (es)
SK (1) SK286245B6 (es)
TR (1) TR199901379A2 (es)
TW (1) TW590774B (es)
UA (1) UA59383C2 (es)
UY (1) UY25649A1 (es)
ZA (1) ZA993938B (es)

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Also Published As

Publication number Publication date
GT199900080A (es) 2000-11-29
IS2182B (is) 2006-12-15
AP9901579A0 (en) 1999-06-30
IS5079A (is) 1999-12-16
HU226487B1 (en) 2009-03-02
DE69908021T2 (de) 2003-11-27
CN1307994C (zh) 2007-04-04
KR20000006143A (ko) 2000-01-25
EA199900467A3 (ru) 2000-04-24
IL130424A0 (en) 2000-06-01
UA59383C2 (uk) 2003-09-15
DE69908021D1 (de) 2003-06-26
CY2003002I1 (el) 2009-11-04
HUP9901960A2 (hu) 2000-08-28
NO992892D0 (no) 1999-06-14
MY121397A (en) 2006-01-28
EP0965343A2 (en) 1999-12-22
MA26647A1 (fr) 2004-12-20
EA002223B1 (ru) 2002-02-28
PL333737A1 (en) 1999-12-20
BG64691B1 (bg) 2005-12-30
TW590774B (en) 2004-06-11
SG77243A1 (en) 2000-12-19
CZ297954B6 (cs) 2007-05-09
AP1216A (en) 2003-10-19
HUP9901960A3 (en) 2000-09-28
DK0965343T3 (da) 2003-08-04
HU9901960D0 (en) 1999-08-30
JP3441676B2 (ja) 2003-09-02
JP2002003492A (ja) 2002-01-09
ID23546A (id) 2000-05-04
CO5070579A1 (es) 2001-08-28
EP0965343B1 (en) 2003-05-21
PT965343E (pt) 2003-08-29
CN1242987A (zh) 2000-02-02
KR100338915B1 (ko) 2002-05-30
CZ212799A3 (cs) 2000-09-13
AR015553A1 (es) 2001-05-02
HRP990193A2 (en) 2000-02-29
HK1024184A1 (en) 2000-10-05
US6150366A (en) 2000-11-21
PA8475601A1 (es) 2000-09-29
UY25649A1 (es) 2000-02-23
BR9902268A (pt) 2000-05-02
HN1999000089A (es) 1999-11-03
PL195606B1 (pl) 2007-10-31
JP2000007566A (ja) 2000-01-11
AU753820B2 (en) 2002-10-31
AU3398399A (en) 1999-12-23
SK76999A3 (en) 2000-12-11
SK286245B6 (sk) 2008-06-06
SI0965343T1 (en) 2003-10-31
ES2197581T3 (es) 2004-01-01
NO992892L (no) 1999-12-16
EP0965343A3 (en) 2000-02-23
OA11064A (en) 2002-03-13
ATE240732T1 (de) 2003-06-15
NO316713B1 (no) 2004-04-13
HRP990193B1 (en) 2003-08-31
BG103489A (en) 2000-07-31
CA2274338A1 (en) 1999-12-15
RS49611B (sr) 2007-06-04
NZ336271A (en) 2000-10-27
IL130424A (en) 2003-10-31
EA199900467A2 (ru) 1999-12-29
JP4187423B2 (ja) 2008-11-26
TR199901379A2 (xx) 2000-01-21
ZA993938B (en) 2000-12-14
YU27199A (sh) 2002-12-10
PL195209B1 (pl) 2007-08-31
CA2274338C (en) 2003-04-15

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