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LT3140008T - Greitai veikiančios insulino kompozicijos - Google Patents

Greitai veikiančios insulino kompozicijos

Info

Publication number
LT3140008T
LT3140008T LTEP15723388.3T LT15723388T LT3140008T LT 3140008 T LT3140008 T LT 3140008T LT 15723388 T LT15723388 T LT 15723388T LT 3140008 T LT3140008 T LT 3140008T
Authority
LT
Lithuania
Prior art keywords
rapid
acting insulin
insulin compositions
compositions
acting
Prior art date
Application number
LTEP15723388.3T
Other languages
English (en)
Inventor
Michael Edward CHRISTE
Thomas Andrew HARDY
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53189204&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT3140008(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of LT3140008T publication Critical patent/LT3140008T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A61K31/5585Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes having five-membered rings containing oxygen as the only ring hetero atom, e.g. prostacyclin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
LTEP15723388.3T 2014-05-08 2015-05-04 Greitai veikiančios insulino kompozicijos LT3140008T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461990402P 2014-05-08 2014-05-08
PCT/US2015/029010 WO2015171484A1 (en) 2014-05-08 2015-05-04 Rapid-acting insulin compositions

Publications (1)

Publication Number Publication Date
LT3140008T true LT3140008T (lt) 2019-05-27

Family

ID=53189204

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP15723388.3T LT3140008T (lt) 2014-05-08 2015-05-04 Greitai veikiančios insulino kompozicijos
LTEP19161129.2T LT3536380T (lt) 2014-05-08 2015-05-04 Greitai veikiančios insulino kompozicijos

Family Applications After (1)

Application Number Title Priority Date Filing Date
LTEP19161129.2T LT3536380T (lt) 2014-05-08 2015-05-04 Greitai veikiančios insulino kompozicijos

Country Status (36)

Country Link
US (2) US9439952B2 (lt)
EP (3) EP3140008B1 (lt)
JP (1) JP6050902B2 (lt)
KR (1) KR101858890B1 (lt)
CN (1) CN106456717B (lt)
AP (1) AP2016009525A0 (lt)
AR (1) AR100155A1 (lt)
AU (1) AU2015256355B2 (lt)
BR (1) BR112016024357B1 (lt)
CA (1) CA2945188C (lt)
CL (1) CL2016002772A1 (lt)
CY (2) CY1121669T1 (lt)
DK (2) DK3536380T3 (lt)
EA (1) EA031134B1 (lt)
ES (2) ES2733639T3 (lt)
HR (2) HRP20190777T1 (lt)
HU (2) HUE044370T2 (lt)
IL (1) IL248350B (lt)
JO (1) JO3624B1 (lt)
LT (2) LT3140008T (lt)
MA (1) MA39441A1 (lt)
ME (1) ME03384B (lt)
MX (1) MX367521B (lt)
NZ (1) NZ724919A (lt)
PE (1) PE20161408A1 (lt)
PH (1) PH12016502195B1 (lt)
PL (2) PL3140008T3 (lt)
PT (2) PT3536380T (lt)
RS (2) RS58726B1 (lt)
SG (1) SG11201608424WA (lt)
SI (2) SI3536380T1 (lt)
TN (1) TN2016000443A1 (lt)
TR (1) TR201906843T4 (lt)
TW (1) TWI685348B (lt)
UA (1) UA124919C2 (lt)
WO (1) WO2015171484A1 (lt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2910570T3 (en) 2008-03-18 2017-01-30 Novo Nordisk As Protease-stabilized acylated insulin analogues.
EP2919804B1 (fr) 2012-11-13 2018-01-31 Adocia Formulation à action rapide d'insuline comprenant un composé anionique substitué
JP6542128B2 (ja) 2013-01-11 2019-07-10 コルセア ファーマ インコーポレイテッド トレプロスチニルのプロドラッグ
US9505737B2 (en) 2013-01-11 2016-11-29 Corsair Pharma, Inc. Treprostinil derivative compounds and methods of using same
WO2017015760A1 (en) * 2015-07-28 2017-02-02 Societe De Commercialisation Des Produits De La Recherche Appliquee Socpra Sciences Sante Et Humaines, S.E.C. A pharmaceutical preparation for improving absorption and postprandial hypoglycemic action of insulin
JO3749B1 (ar) * 2015-08-27 2021-01-31 Lilly Co Eli تركيبات إنسولين سريعة المفعول
IL260823B2 (en) * 2016-01-29 2024-08-01 Mannkind Corp Dry powder inhaler
GB201607918D0 (en) 2016-05-06 2016-06-22 Arecor Ltd Novel formulations
EP3515430A1 (en) 2016-09-26 2019-07-31 United Therapeutics Corporation Treprostinil prodrugs
WO2018060735A1 (en) 2016-09-29 2018-04-05 Arecor Limited Novel formulations
TWI700091B (zh) 2016-12-16 2020-08-01 丹麥商諾佛 儂迪克股份有限公司 含胰島素醫藥組成物
GB201707188D0 (en) 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
GB201707189D0 (en) 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
GB201707187D0 (en) 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
IL270975B2 (en) 2017-06-01 2024-02-01 Lilly Co Eli Fast-acting insulin preparations
IL277721B2 (en) 2018-04-04 2024-03-01 Arecor Ltd Medical infusion pump system for the delivery of an insulin compound
CA3094304A1 (en) 2018-04-04 2019-10-10 Arecor Limited Medical infusion pump system for the delivery of an insulin compound
CN112040928A (zh) 2018-04-04 2020-12-04 艾瑞克有限公司 用于递送胰岛素化合物的医用输注泵系统
WO2019243627A1 (fr) 2018-06-23 2019-12-26 Adocia Dispositif pour injecter une solution d'insuline(s)
FR3083985A1 (fr) 2018-07-23 2020-01-24 Adocia Dispositif pour injecter une solution d'insuline(s)
EA202190552A1 (ru) 2018-09-18 2021-06-18 Эли Лилли Энд Компани Эрбуминовая соль трепростинила
US10799564B1 (en) * 2019-05-06 2020-10-13 Baxter International Inc. Insulin premix formulation and product, methods of preparing same, and methods of using same
WO2021009027A1 (en) 2019-07-12 2021-01-21 Novo Nordisk A/S High concentration insulin formulation
EP4017588A1 (en) 2019-08-23 2022-06-29 United Therapeutics Corporation Treprostinil prodrugs
GB202004814D0 (en) 2020-04-01 2020-05-13 Arecor Ltd Novel formulations
CN115916212A (zh) 2020-04-17 2023-04-04 联合治疗公司 曲前列尼尔用于治疗间质性肺病
AU2021289336B2 (en) 2020-06-09 2025-08-28 Mannkind Corporation Fumaryl diketopiperidine prodrugs of treprostinil
CN115697379A (zh) * 2020-06-30 2023-02-03 江苏恒瑞医药股份有限公司 速效胰岛素组合物及其医药用途
CN117062605A (zh) 2020-12-14 2023-11-14 联合治疗公司 使用曲前列环素前药治疗疾病的方法
CN117479946A (zh) 2021-03-03 2024-01-30 联合治疗公司 含曲前列环素及其前药并还包含(e)-3,6-双[4-(n-羰基-2-丙烯基)酰胺丁基]-2,5-二酮哌嗪(fdkp)的干粉组合物
JP2025515512A (ja) * 2022-04-29 2025-05-15 兆科薬業(広州)有限公司 トレプロスチニルソフトミスト吸入剤

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2740953A1 (de) 1977-09-12 1979-03-22 Thera Ges Fuer Patente Verwendung von prostaglandinen zur senkung des blutzuckerspiegels
JPH10251146A (ja) * 1997-03-11 1998-09-22 Toray Ind Inc 糖尿病性神経障害の治療方法
WO2003020201A2 (en) * 2001-08-28 2003-03-13 Eli Lilly And Company Pre-mixes of glp-1 and basal insulin
ATE496064T1 (de) 2002-05-07 2011-02-15 Novo Nordisk As Lösliche formulierungen, die monomeres insulin und acyliertes insulin enthalten
DE602005020269D1 (de) * 2004-04-12 2010-05-12 United Therapeutics Corp Verwendung von treprostinil zur behandlung von neuropathischen diabetischen fussgeschwüren
WO2009026517A2 (en) * 2007-08-22 2009-02-26 Gilead Colorado, Inc. Therapy for complications of diabetes
US9387033B2 (en) 2008-08-28 2016-07-12 Roche Diabetes Care, Inc. Device and method for enhanced subcutaneous insulin absorption
WO2010036798A1 (en) * 2008-09-25 2010-04-01 Aradigm Corporation Deep lung pulmonary delivery of treprostinil
MX2011012764A (es) * 2009-06-26 2012-01-20 Novo Nordisk As Preparacion que comprende insulina, nicotinamida y un aminoacido.
KR101701943B1 (ko) * 2009-11-13 2017-02-02 도레이 카부시키가이샤 당뇨병의 치료 또는 예방약
CA2821613A1 (en) 2010-12-14 2012-06-21 Novo Nordisk A/S Preparation comprising insulin, nicotinamide and an amino acid
CA2843883C (en) * 2011-08-12 2020-04-28 Ascendis Pharma A/S Carrier-linked treprostinil prodrugs
US9381247B2 (en) * 2012-04-16 2016-07-05 Biodel Inc. Magnesium compositions for modulating the pharmacokinetics and pharmacodynamics of insulin and insulin analogs, and injection site pain
US20150065423A1 (en) 2013-08-30 2015-03-05 Perosphere, Inc. Rapid acting injectable formulations
US20150273022A1 (en) 2014-02-10 2015-10-01 Biodel Inc. Stabilized ultra-rapid-acting insulin formulations

Also Published As

Publication number Publication date
EP3536380B8 (en) 2021-09-22
WO2015171484A1 (en) 2015-11-12
CN106456717B (zh) 2020-01-17
TN2016000443A1 (en) 2018-04-04
MX367521B (es) 2019-08-26
SG11201608424WA (en) 2016-11-29
HUE055742T2 (hu) 2021-12-28
EP3536380B1 (en) 2021-07-07
IL248350B (en) 2020-03-31
US9439952B2 (en) 2016-09-13
CL2016002772A1 (es) 2017-06-09
DK3140008T3 (da) 2019-06-24
HRP20211415T1 (hr) 2021-12-10
SI3536380T1 (sl) 2021-09-30
MX2016014643A (es) 2017-03-06
ES2733639T3 (es) 2019-12-02
PE20161408A1 (es) 2016-12-28
US20160367640A1 (en) 2016-12-22
PL3536380T3 (pl) 2021-12-27
MA39441A1 (fr) 2017-06-30
US20160129087A1 (en) 2016-05-12
TR201906843T4 (tr) 2019-05-21
IL248350A0 (en) 2016-11-30
AP2016009525A0 (en) 2016-10-31
PT3536380T (pt) 2021-09-02
DK3536380T3 (da) 2021-08-02
TW201625291A (zh) 2016-07-16
AU2015256355B2 (en) 2017-09-14
KR101858890B1 (ko) 2018-05-16
PH12016502195A1 (en) 2017-02-06
UA124919C2 (uk) 2021-12-15
US10172922B2 (en) 2019-01-08
AU2015256355A1 (en) 2016-10-27
JP6050902B2 (ja) 2016-12-21
PT3140008T (pt) 2019-06-25
CA2945188A1 (en) 2015-11-12
EP3943155A1 (en) 2022-01-26
CN106456717A (zh) 2017-02-22
EA201691911A1 (ru) 2017-02-28
TWI685348B (zh) 2020-02-21
CY1124454T1 (el) 2022-07-22
JO3624B1 (ar) 2020-08-27
EP3536380A1 (en) 2019-09-11
EP3140008B1 (en) 2019-04-17
CY1121669T1 (el) 2020-07-31
BR112016024357B1 (pt) 2022-08-23
KR20160133567A (ko) 2016-11-22
BR112016024357A2 (pt) 2017-10-10
HRP20190777T1 (hr) 2019-08-23
AR100155A1 (es) 2016-09-14
NZ724919A (en) 2018-01-26
ME03384B (me) 2020-01-20
PL3140008T3 (pl) 2019-09-30
EA031134B1 (ru) 2018-11-30
LT3536380T (lt) 2021-08-10
ES2891983T3 (es) 2022-02-01
HUE044370T2 (hu) 2019-10-28
RS58726B1 (sr) 2019-06-28
PH12016502195B1 (en) 2017-02-06
SI3140008T1 (sl) 2019-06-28
EP3140008A1 (en) 2017-03-15
JP2016523807A (ja) 2016-08-12
RS62291B1 (sr) 2021-09-30
CA2945188C (en) 2018-12-11

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