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CL2016002772A1 - Composiciones de insulina de rápida acción - Google Patents

Composiciones de insulina de rápida acción

Info

Publication number
CL2016002772A1
CL2016002772A1 CL2016002772A CL2016002772A CL2016002772A1 CL 2016002772 A1 CL2016002772 A1 CL 2016002772A1 CL 2016002772 A CL2016002772 A CL 2016002772A CL 2016002772 A CL2016002772 A CL 2016002772A CL 2016002772 A1 CL2016002772 A1 CL 2016002772A1
Authority
CL
Chile
Prior art keywords
fast
acting insulin
insulin compositions
compositions
acting
Prior art date
Application number
CL2016002772A
Other languages
English (en)
Inventor
Michael Edward Christe
Thomas Andrew Hardy
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53189204&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2016002772(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CL2016002772A1 publication Critical patent/CL2016002772A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A61K31/5585Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes having five-membered rings containing oxygen as the only ring hetero atom, e.g. prostacyclin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

<p>COMPOSICION FARMACÉUTICA QUE COMPRENDE INSULINA Y TREPROSTINIL.</p>
CL2016002772A 2014-05-08 2016-11-02 Composiciones de insulina de rápida acción CL2016002772A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201461990402P 2014-05-08 2014-05-08

Publications (1)

Publication Number Publication Date
CL2016002772A1 true CL2016002772A1 (es) 2017-06-09

Family

ID=53189204

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2016002772A CL2016002772A1 (es) 2014-05-08 2016-11-02 Composiciones de insulina de rápida acción

Country Status (36)

Country Link
US (2) US9439952B2 (es)
EP (3) EP3140008B1 (es)
JP (1) JP6050902B2 (es)
KR (1) KR101858890B1 (es)
CN (1) CN106456717B (es)
AP (1) AP2016009525A0 (es)
AR (1) AR100155A1 (es)
AU (1) AU2015256355B2 (es)
BR (1) BR112016024357B1 (es)
CA (1) CA2945188C (es)
CL (1) CL2016002772A1 (es)
CY (2) CY1121669T1 (es)
DK (2) DK3140008T3 (es)
EA (1) EA031134B1 (es)
ES (2) ES2733639T3 (es)
HR (2) HRP20190777T1 (es)
HU (2) HUE055742T2 (es)
IL (1) IL248350B (es)
JO (1) JO3624B1 (es)
LT (2) LT3140008T (es)
MA (1) MA39441A1 (es)
ME (1) ME03384B (es)
MX (1) MX367521B (es)
NZ (1) NZ724919A (es)
PE (1) PE20161408A1 (es)
PH (1) PH12016502195B1 (es)
PL (2) PL3140008T3 (es)
PT (2) PT3140008T (es)
RS (2) RS58726B1 (es)
SG (1) SG11201608424WA (es)
SI (2) SI3536380T1 (es)
TN (1) TN2016000443A1 (es)
TR (1) TR201906843T4 (es)
TW (1) TWI685348B (es)
UA (1) UA124919C2 (es)
WO (1) WO2015171484A1 (es)

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MX2010009850A (es) 2008-03-18 2010-09-30 Novo Nordisk As Analogos de insulina acilados y etabilizados contra proteasas.
EP2919804B1 (fr) 2012-11-13 2018-01-31 Adocia Formulation à action rapide d'insuline comprenant un composé anionique substitué
JP6542128B2 (ja) 2013-01-11 2019-07-10 コルセア ファーマ インコーポレイテッド トレプロスチニルのプロドラッグ
US9505737B2 (en) 2013-01-11 2016-11-29 Corsair Pharma, Inc. Treprostinil derivative compounds and methods of using same
EP3328388B1 (en) * 2015-07-28 2023-12-27 Eli Lilly and Company A pharmaceutical preparation for improving absorption and postprandial hypoglycemic action of insulin
JO3749B1 (ar) * 2015-08-27 2021-01-31 Lilly Co Eli تركيبات إنسولين سريعة المفعول
EP4079291A1 (en) * 2016-01-29 2022-10-26 MannKind Corporation Dry powder inhaler
GB201607918D0 (en) 2016-05-06 2016-06-22 Arecor Ltd Novel formulations
CA3038276A1 (en) 2016-09-26 2018-03-29 United Therapeutics Corporation Treprostinil prodrugs
DK3518892T5 (da) 2016-09-29 2024-09-02 Arecor Ltd Farmaceutisk formulering, der indeholder en insulinforbindelse
AU2017378102B2 (en) 2016-12-16 2022-10-13 Novo Nordisk A/S Insulin containing pharmaceutical compositions
GB201707189D0 (en) 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
GB201707188D0 (en) 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
GB201707187D0 (en) 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
WO2018222787A1 (en) 2017-06-01 2018-12-06 Eli Lilly And Company Rapid-acting insulin compositions
CN112040928A (zh) 2018-04-04 2020-12-04 艾瑞克有限公司 用于递送胰岛素化合物的医用输注泵系统
IL277721B2 (en) 2018-04-04 2024-03-01 Arecor Ltd Medical infusion pump system for the delivery of an insulin compound
IL277731B2 (en) * 2018-04-04 2024-03-01 Arecor Ltd Medical infusion pump system for the delivery of an insulin compound
FR3083985A1 (fr) 2018-07-23 2020-01-24 Adocia Dispositif pour injecter une solution d'insuline(s)
WO2019243627A1 (fr) 2018-06-23 2019-12-26 Adocia Dispositif pour injecter une solution d'insuline(s)
IL280891B1 (en) 2018-09-18 2025-09-01 Lilly Co Eli Treprostinil erbumine salt
US10799564B1 (en) 2019-05-06 2020-10-13 Baxter International Inc. Insulin premix formulation and product, methods of preparing same, and methods of using same
JP7518149B2 (ja) * 2019-07-12 2024-07-17 ノヴォ ノルディスク アー/エス 高濃度インスリン製剤
CN114616225A (zh) 2019-08-23 2022-06-10 联合治疗公司 曲前列环素前药
GB202004814D0 (en) 2020-04-01 2020-05-13 Arecor Ltd Novel formulations
WO2021211916A1 (en) 2020-04-17 2021-10-21 United Therapeutics Corporation Treprostinil for use in the treatment of intersitial lung disease
US11793780B2 (en) 2020-06-09 2023-10-24 United Therapeutics Corporation Prodrugs of treprosiinil
TW202214292A (zh) * 2020-06-30 2022-04-16 大陸商江蘇恆瑞醫藥股份有限公司 速效胰島素組成物及其醫藥用途
WO2022132655A1 (en) 2020-12-14 2022-06-23 United Therapeutics Corporation Methods of treating disease with treprostinil prodrugs
EP4301372A1 (en) 2021-03-03 2024-01-10 United Therapeutics Corporation A dry powder composition of trestinil and its prodrug thereof and further comprising comprising (e)-3,6-bis[4-(n-carbonyl-2-propenyl)amidobutyl]-2,5-diketopiperazine (fdkp)
KR20250002687A (ko) * 2022-04-29 2025-01-07 자오커 파마슈티컬 (광저우) 컴퍼니., 리미티드 트레프로스티닐 소프트 미스트 흡입제

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DE2740953A1 (de) 1977-09-12 1979-03-22 Thera Ges Fuer Patente Verwendung von prostaglandinen zur senkung des blutzuckerspiegels
JPH10251146A (ja) * 1997-03-11 1998-09-22 Toray Ind Inc 糖尿病性神経障害の治療方法
CA2452044A1 (en) * 2001-08-28 2003-03-13 Eli Lilly And Company Pre-mixes of glp-1 and basal insulin
ES2360182T3 (es) 2002-05-07 2011-06-01 Novo Nordisk A/S Formulaciones solubles que comprenden insulina monomérica e insulina acilada.
JP2007532663A (ja) * 2004-04-12 2007-11-15 ユナイテッド セラピューティクス インコーポレイテッド ニューロパシー性の糖尿病性足潰瘍を治療するためのトレプロスチニルの使用
CA2697057A1 (en) * 2007-08-22 2009-02-26 Gilead Colorado, Inc. Therapy for complications of diabetes
DK2626093T3 (en) 2008-08-28 2014-02-24 Hoffmann La Roche DEVICE FOR INCREASING HYPODERMIC insulin absorption
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BRPI1014760B8 (pt) * 2009-06-26 2021-05-25 Novo Nordisk As preparação compreendendo insulina, nicotinamida e arginina
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US9381247B2 (en) * 2012-04-16 2016-07-05 Biodel Inc. Magnesium compositions for modulating the pharmacokinetics and pharmacodynamics of insulin and insulin analogs, and injection site pain
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US20150273022A1 (en) 2014-02-10 2015-10-01 Biodel Inc. Stabilized ultra-rapid-acting insulin formulations

Also Published As

Publication number Publication date
SI3536380T1 (sl) 2021-09-30
CA2945188A1 (en) 2015-11-12
TN2016000443A1 (en) 2018-04-04
SI3140008T1 (sl) 2019-06-28
CA2945188C (en) 2018-12-11
MX367521B (es) 2019-08-26
HUE044370T2 (hu) 2019-10-28
TR201906843T4 (tr) 2019-05-21
AU2015256355A1 (en) 2016-10-27
BR112016024357B1 (pt) 2022-08-23
CY1121669T1 (el) 2020-07-31
EP3140008B1 (en) 2019-04-17
CN106456717B (zh) 2020-01-17
HRP20211415T1 (hr) 2021-12-10
LT3536380T (lt) 2021-08-10
NZ724919A (en) 2018-01-26
AU2015256355B2 (en) 2017-09-14
MX2016014643A (es) 2017-03-06
TW201625291A (zh) 2016-07-16
US20160129087A1 (en) 2016-05-12
US20160367640A1 (en) 2016-12-22
EP3943155A1 (en) 2022-01-26
KR20160133567A (ko) 2016-11-22
ME03384B (me) 2020-01-20
IL248350B (en) 2020-03-31
EP3536380A1 (en) 2019-09-11
CN106456717A (zh) 2017-02-22
CY1124454T1 (el) 2022-07-22
EA201691911A1 (ru) 2017-02-28
AR100155A1 (es) 2016-09-14
RS58726B1 (sr) 2019-06-28
EP3536380B8 (en) 2021-09-22
EP3536380B1 (en) 2021-07-07
IL248350A0 (en) 2016-11-30
US9439952B2 (en) 2016-09-13
PL3536380T3 (pl) 2021-12-27
UA124919C2 (uk) 2021-12-15
EA031134B1 (ru) 2018-11-30
MA39441A1 (fr) 2017-06-30
WO2015171484A1 (en) 2015-11-12
SG11201608424WA (en) 2016-11-29
BR112016024357A2 (pt) 2017-10-10
ES2891983T3 (es) 2022-02-01
EP3140008A1 (en) 2017-03-15
JP2016523807A (ja) 2016-08-12
US10172922B2 (en) 2019-01-08
PE20161408A1 (es) 2016-12-28
JO3624B1 (ar) 2020-08-27
LT3140008T (lt) 2019-05-27
RS62291B1 (sr) 2021-09-30
TWI685348B (zh) 2020-02-21
JP6050902B2 (ja) 2016-12-21
PT3536380T (pt) 2021-09-02
DK3140008T3 (da) 2019-06-24
KR101858890B1 (ko) 2018-05-16
AP2016009525A0 (en) 2016-10-31
PH12016502195A1 (en) 2017-02-06
PH12016502195B1 (en) 2017-02-06
PL3140008T3 (pl) 2019-09-30
PT3140008T (pt) 2019-06-25
ES2733639T3 (es) 2019-12-02
HRP20190777T1 (hr) 2019-08-23
DK3536380T3 (da) 2021-08-02
HUE055742T2 (hu) 2021-12-28

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