IS5627A - Svefnlyfs ß-karbólín afleiður, aðferð til framleiðslu á þeim og notkun þeirra sem læknislyfja - Google Patents

Svefnlyfs ß-karbólín afleiður, aðferð til framleiðslu á þeim og notkun þeirra sem læknislyfja

Info

Publication number: IS5627A
Authority: IS; Iceland
Prior art keywords: hypnotic; preparation; medicinal products; carboline derivatives; carboline
Prior art date: 1998-03-17

Application number

IS5627A

Other languages

English (en)

Other versions

IS2199B (is

Inventor

Fourtillan Jean-Bernard

Fourtillan Marianne

Jacquesy Jean-Claude

Jouannetaud Marie-Paule

Violeau Bruno

Karam Omar

Original Assignee

Macef

Laboratoires Besins Iscovesco

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-17

Filing date

2000-09-12

Publication date

2000-09-12

1998-03-17 Priority claimed from US09/042,990 external-priority patent/US6048868A/en

2000-09-12 Application filed by Macef, Laboratoires Besins Iscovesco filed Critical Macef

2000-09-12 Publication of IS5627A publication Critical patent/IS5627A/is

2007-02-15 Publication of IS2199B publication Critical patent/IS2199B/is

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Anesthesiology (AREA)
Gynecology & Obstetrics (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)

IS5627A 1998-03-17 2000-09-12 Svæfandi ß-karbólín afleiður, aðferð til framleiðslu þeirra og notkun þeirra sem læknislyf IS2199B (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/042,990 US6048868A (en)	1994-09-14	1998-03-17	Melatonin-antagonist β-carboline derivatives and analogues thereof containing naphthalenic structure, process for their preparation and their use as medicinal products
PCT/IB1999/000494 WO1999047521A1 (en)	1998-03-17	1999-03-17	HYPNOTIC β-CARBOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINAL PRODUCTS

Publications (2)

Publication Number	Publication Date
IS5627A true IS5627A (is)	2000-09-12
IS2199B IS2199B (is)	2007-02-15

Family

ID=21924862

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS5627A IS2199B (is)	1998-03-17	2000-09-12	Svæfandi ß-karbólín afleiður, aðferð til framleiðslu þeirra og notkun þeirra sem læknislyf

Country Status (24)

Country	Link
EP (1)	EP1064284B1 (is)
JP (1)	JP4333036B2 (is)
CN (1)	CN1115342C (is)
AR (1)	AR018767A1 (is)
AT (1)	ATE215087T1 (is)
AU (1)	AU752364B2 (is)
BG (1)	BG63973B1 (is)
BR (1)	BR9908833A (is)
CA (1)	CA2324270A1 (is)
DE (1)	DE69901098T2 (is)
DK (1)	DK1064284T3 (is)
ES (1)	ES2174632T3 (is)
HU (1)	HUP0101234A3 (is)
IL (1)	IL138442A (is)
IS (1)	IS2199B (is)
NO (1)	NO317296B1 (is)
NZ (1)	NZ506913A (is)
PL (1)	PL193450B1 (is)
PT (1)	PT1064284E (is)
RU (1)	RU2210571C2 (is)
SK (1)	SK284387B6 (is)
TR (1)	TR200003596T2 (is)
UA (1)	UA71911C2 (is)
WO (1)	WO1999047521A1 (is)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2824829B1 (fr) *	2001-05-16	2005-06-03	Macef	Nouveaux derives de dihydroimidazo [5,1-a]-beta-carboline, leur procede de preparation et leur application a titre de medicament
FR2904973A1 (fr) *	2006-08-18	2008-02-22	Fourtillan Snc	Derives de 1-methylidene-pyrido[3,4-b]indole et leur utilisation en therapeutique.
FR2916200A1 (fr) *	2007-05-18	2008-11-21	Fourtillan Snc	Nouveaux derives des 1,2,3,4,6,7,12,12a-octahydro pyrazino[1',2':1,6]pyrido[3,4-b]indoles, leur preparation et leur utilisation en therapeutique
EP2240481A1 (en)	2008-01-11	2010-10-20	Albany Molecular Research, Inc.	(1-azinone) -substituted pyridoindoles as mch antagonists
US8629158B2 (en)	2009-07-01	2014-01-14	Albany Molecular Research, Inc.	Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof
WO2011003021A1 (en)	2009-07-01	2011-01-06	Albany Molecular Research, Inc.	Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
WO2011003012A1 (en)	2009-07-01	2011-01-06	Albany Molecular Research, Inc.	Azinone-substituted azapolycycle mch-1 antagonists, methods of making, and use thereof
WO2011003005A1 (en)	2009-07-01	2011-01-06	Albany Molecular Research, Inc.	Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine mch-1 antagonists, methods of making, and use thereof
WO2012088124A2 (en)	2010-12-21	2012-06-28	Albany Molecular Research, Inc.	Tetrahydro-azacarboline mch-1 antagonists, methods of making, and uses thereof
WO2012088038A2 (en)	2010-12-21	2012-06-28	Albany Molecular Research, Inc.	Piperazinone-substituted tetrahydro-carboline mch-1 antagonists, methods of making, and uses thereof
FI130627B (en) *	2021-03-31	2023-12-18	Equinorm Ltd	Novel heterocyclic compounds and their use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5283343A (en) *	1987-08-17	1994-02-01	Whitby Research, Inc.	2-aryl substituted N-acetyltryptamines and process of preparing such
HU207070B (en) *	1990-10-31	1993-03-01	Richter Gedeon Vegyeszet	Process for producing 1beta-ethyl-1alpha-hydroxymethyl-1,2,3,4,6,712,12balpha-octahydroindolo(2,3-a) quinolizine
RU2067980C1 (ru) *	1992-06-30	1996-10-20	Глэксо Груп Лимитед	Производные лактама и фармацевтическая композиция, являющаяся антагонистом 5-окситраптамина /5-нт/ на 5- нт3 -рецепторах или их физиологически приемлемые соли и соловаты
RU2068847C1 (ru) *	1994-05-18	1996-11-10	Всероссийский научный центр по безопасности биологически активных веществ	ПРОИЗВОДНЫЕ 3,4-ДИГИДРО- ИЛИ 1,2,3,4-ТЕТРАГИДРО- β -КАРБОЛИНОВ ИЛИ ИХ СОЛИ С ОРГАНИЧЕСКИМИ ИЛИ НЕОРГАНИЧЕСКИМИ КИСЛОТАМИ, ПРОЯВЛЯЮЩИЕ АНТИМИКРОБНУЮ АКТИВНОСТЬ
FR2724384B1 (fr) *	1994-09-14	1999-04-16	Cemaf	Nouveaux derives de la 3,4-dihydro beta-carboline agonistes de la melatonine, leur procede de preparation et leur utilisation a titre de medicament

1999
- 1999-03-17 PL PL99342929A patent/PL193450B1/pl not_active IP Right Cessation
- 1999-03-17 NZ NZ506913A patent/NZ506913A/en unknown
- 1999-03-17 ES ES99939844T patent/ES2174632T3/es not_active Expired - Lifetime
- 1999-03-17 AT AT99939844T patent/ATE215087T1/de not_active IP Right Cessation
- 1999-03-17 SK SK1385-2000A patent/SK284387B6/sk not_active IP Right Cessation
- 1999-03-17 BR BR9908833-9A patent/BR9908833A/pt not_active Application Discontinuation
- 1999-03-17 RU RU2000126288/04A patent/RU2210571C2/ru not_active IP Right Cessation
- 1999-03-17 AR ARP990101166A patent/AR018767A1/es active IP Right Grant
- 1999-03-17 IL IL138442A patent/IL138442A/en not_active IP Right Cessation
- 1999-03-17 AU AU32707/99A patent/AU752364B2/en not_active Ceased
- 1999-03-17 WO PCT/IB1999/000494 patent/WO1999047521A1/en not_active Ceased
- 1999-03-17 DE DE69901098T patent/DE69901098T2/de not_active Expired - Lifetime
- 1999-03-17 UA UA2000105839A patent/UA71911C2/uk unknown
- 1999-03-17 TR TR2000/03596T patent/TR200003596T2/xx unknown
- 1999-03-17 DK DK99939844T patent/DK1064284T3/da active
- 1999-03-17 CA CA002324270A patent/CA2324270A1/en not_active Abandoned
- 1999-03-17 EP EP99939844A patent/EP1064284B1/en not_active Expired - Lifetime
- 1999-03-17 HU HU0101234A patent/HUP0101234A3/hu unknown
- 1999-03-17 PT PT99939844T patent/PT1064284E/pt unknown
- 1999-03-17 CN CN99805687A patent/CN1115342C/zh not_active Expired - Fee Related
- 1999-03-17 JP JP2000536716A patent/JP4333036B2/ja not_active Expired - Fee Related
2000
- 2000-09-12 IS IS5627A patent/IS2199B/is unknown
- 2000-09-14 BG BG104768A patent/BG63973B1/bg unknown
- 2000-09-15 NO NO20004638A patent/NO317296B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
TR200003596T2 (tr)	2001-04-20
NO20004638L (no)	2000-11-16
IL138442A (en)	2006-12-10
RU2210571C2 (ru)	2003-08-20
ES2174632T3 (es)	2002-11-01
NO20004638D0 (no)	2000-09-15
UA71911C2 (en)	2005-01-17
AU3270799A (en)	1999-10-11
PL342929A1 (en)	2001-07-16
NZ506913A (en)	2003-07-25
PT1064284E (pt)	2002-09-30
PL193450B1 (pl)	2007-02-28
IL138442A0 (en)	2001-10-31
HUP0101234A2 (hu)	2001-12-28
AU752364B2 (en)	2002-09-19
DK1064284T3 (da)	2002-07-22
BG63973B1 (bg)	2003-08-29
HUP0101234A3 (en)	2002-12-28
DE69901098T2 (de)	2002-11-21
DE69901098D1 (de)	2002-05-02
BG104768A (en)	2001-05-31
NO317296B1 (no)	2004-10-04
JP2002506867A (ja)	2002-03-05
CN1299361A (zh)	2001-06-13
AR018767A1 (es)	2001-12-12
JP4333036B2 (ja)	2009-09-16
SK13852000A3 (sk)	2001-09-11
SK284387B6 (sk)	2005-02-04
CA2324270A1 (en)	1999-09-23
IS2199B (is)	2007-02-15
BR9908833A (pt)	2000-11-21
WO1999047521A1 (en)	1999-09-23
CN1115342C (zh)	2003-07-23
EP1064284A1 (en)	2001-01-03
ATE215087T1 (de)	2002-04-15
EP1064284B1 (en)	2002-03-27

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IS2156B (is)	2006-11-15	Settar bensensúlfonamíðafleiður sem forlyf fyrir COX-2 tálma, aðferð til þess að búa þær til, lyfjasamsetningar sem innihalda þær og notkun þeirra við framleiðslu lyfja
NO20014013L (no)	2001-10-18	16-halogen-epotilonderivater, fremgangsmåter for fremstilling av disse og farmasöytisk anvendelse av dem
IS6724A (is)	2003-02-20	Aðferð til framleiðslu á N-arýl-anþranilískum sýrum og afleiðum þeirra
HUP0104204A3 (en)	2002-06-28	Pyrazolopyridine derivatives as cox-2 inhibitors, process for their preparation and pharmaceutical compositions thereof
NO20001409D0 (no)	2000-03-17	Karboksamidotiazolderivater, fremgangsmåte for fremstilling derav og farmasøytiske blandinger
HUP0201711A3 (en)	2005-05-30	N-indanyl-benzamide derivatives, method for their production, their use and pharmaceutical preparations containing them
HUP0204410A3 (en)	2003-07-28	Pyrimidine-4-one derivatives, process for their preparation, pharmaceutical compositions containing them and their use
IS2076B (is)	2006-02-15	Asýl-píperasínil-pýrimídínafleiður, framleiðsla og notkun þeirra sem lyfja
IL214387A (en)	2015-09-24	History of tryptamine, method for their preparation and use for the preparation of pharmaceuticals and for the preparation of tryptamine
NO20032332D0 (no)	2003-05-22	Benzodiazepinderivatforbindelser, fremgangsmåte til fremstilling og anvendelse derav
NO20015542L (no)	2002-01-14	Fremgangsmåte for fremstilling og anvendelse av N- desmetylzopikloner
NO20022021D0 (no)	2002-04-29	Indeno-, nafto- og benzocyklohepta-dihydrotiazolderivater, fremstilling av de samme og deres anvendelse somanoreksilegemidler
NO20015659D0 (no)	2001-11-20	Purinderivater, fremstillingsmetode og farmasöytiske preparater inneholdende disse
NO20013900L (no)	2001-10-11	Epotilonderivater, fremgangsmåter for fremstilling av disse og farmasöytisk anvendelse av dem
IS5627A (is)	2000-09-12	Svefnlyfs ß-karbólín afleiður, aðferð til framleiðslu á þeim og notkun þeirra sem læknislyfja
HUP0204354A3 (en)	2006-01-30	Novel heterocyclic derivatives, preparation method and pharmaceutical compositions containing same and their use
PL352280A1 (en)	2003-08-11	Derivatives of naphthyridine, method of making same, use of same and pharmaceutical compositions containing these derivatives
DK1275647T3 (da)	2004-03-15	Octahydro-1H-pyrido[1,2-a]pyrazinderivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse
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PL342453A1 (en)	2001-06-04	Biphenylsulphonylcyanamides, method of obtaining them and their application as drugs
IS5654A (is)	2001-04-12	Aðferð til framleiðslu á pýrazóló[4,3-d]pýrimidín-7-ón-3-pýridýlsúlfónýl efnasamböndum og milliefnum af þeim
NO20013141D0 (no)	2001-06-22	Arylalkanoylderivater, fremgangsmåte for fremstilling derav, deres anvendelse og farmasöytiske produkter inneholdende disse
DE60000646D1 (de)	2002-11-28	Pyrrolo[3,4-b]chinolinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
AU2795202A (en)	2002-06-18	Klainetin and derivatives thereof, method for their production and the use of the same