IS2376B - Þíenópýrimidíndíón og notkun þeirra í breytingu ásjálfsnæmissjúkdómi - Google Patents

Þíenópýrimidíndíón og notkun þeirra í breytingu ásjálfsnæmissjúkdómi

Info

Publication number: IS2376B
Authority: IS; Iceland
Prior art keywords: thienopyrimidinedione; sup; self; development; hypersensitivity disease
Prior art date: 2003-01-17

Application number

IS7965A

Other languages

English (en)

Other versions

IS7965A (is

Inventor

David Guile Simon

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-01-17

Filing date

2005-07-29

Publication date

2008-07-15

2005-07-29 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2005-07-29 Publication of IS7965A publication Critical patent/IS7965A/is

2008-07-15 Publication of IS2376B publication Critical patent/IS2376B/is

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Transplantation (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

IS7965A 2003-01-17 2005-07-29 Þíenópýrimidíndíón og notkun þeirra í breytingu ásjálfsnæmissjúkdómi IS2376B (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE0300119A SE0300119D0 (sv)	2003-01-17	2003-01-17	Novel compounds
PCT/SE2004/000052 WO2004065394A1 (en)	2003-01-17	2004-01-15	Thienopyrimidinediones and their use in the modulation of autoimmune disease

Publications (2)

Publication Number	Publication Date
IS7965A IS7965A (is)	2005-07-29
IS2376B true IS2376B (is)	2008-07-15

Family

ID=20290154

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS7965A IS2376B (is)	2003-01-17	2005-07-29	Þíenópýrimidíndíón og notkun þeirra í breytingu ásjálfsnæmissjúkdómi

Country Status (23)

Country	Link
US (2)	US7384951B2 (is)
EP (1)	EP1587812B1 (is)
JP (1)	JP4519121B2 (is)
KR (2)	KR20110125256A (is)
CN (1)	CN100334093C (is)
AT (1)	ATE335748T1 (is)
AU (1)	AU2004206012B2 (is)
BR (1)	BRPI0406801B8 (is)
CA (1)	CA2512441C (is)
DE (1)	DE602004001857T2 (is)
EG (1)	EG25613A (is)
ES (1)	ES2270337T3 (is)
IL (1)	IL169370A (is)
IS (1)	IS2376B (is)
MX (1)	MXPA05007496A (is)
NO (1)	NO333702B1 (is)
NZ (1)	NZ541217A (is)
PL (1)	PL214682B1 (is)
RU (1)	RU2331647C2 (is)
SE (1)	SE0300119D0 (is)
UA (1)	UA81788C2 (is)
WO (1)	WO2004065394A1 (is)
ZA (1)	ZA200505364B (is)

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GB0117583D0 (en) *	2001-07-19	2001-09-12	Astrazeneca Ab	Novel compounds
GB0118479D0 (en) *	2001-07-28	2001-09-19	Astrazeneca Ab	Novel compounds
PL378221A1 (pl) *	2003-01-17	2006-03-20	Astrazeneca Ab	Tienopirydazynony i ich zastosowanie w modulacji choroby autoimmunologicznej
SE0300120D0 (sv)	2003-01-17	2003-01-17	Astrazeneca Ab	Novel compounds
PT1696920E (pt)	2003-12-19	2015-01-14	Plexxikon Inc	Compostos e métodos para o desenvolvimento de moduladores de ret
US7498342B2 (en)	2004-06-17	2009-03-03	Plexxikon, Inc.	Compounds modulating c-kit activity
KR20080027775A (ko)	2005-05-17	2008-03-28	플렉시콘, 인코퍼레이티드	피롤(２,３-ｂ)피리딘 유도체 단백질 키나제 억제제
PL1893612T3 (pl)	2005-06-22	2012-01-31	Plexxikon Inc	Pochodne pirolo-[2,3-b]pirydyny jako inhibitory kinazy białkowej
WO2008063888A2 (en)	2006-11-22	2008-05-29	Plexxikon, Inc.	Compounds modulating c-fms and/or c-kit activity and uses therefor
PE20121126A1 (es)	2006-12-21	2012-08-24	Plexxikon Inc	Compuestos pirrolo [2,3-b] piridinas como moduladores de quinasa
WO2008079909A1 (en)	2006-12-21	2008-07-03	Plexxikon, Inc.	Pyrrolo [2,3-b] pyridines as kinase modulators
JP2010514695A (ja)	2006-12-21	2010-05-06	プレキシコン，インコーポレーテッド	キナーゼ調節のための化合物および方法およびそのための適応症
GB0713479D0 (en) *	2007-07-11	2007-08-22	Syngenta Participations Ag	Substituted aromatic heterocyclic compounds as fungicides
BRPI0814423B1 (pt)	2007-07-17	2022-04-19	Plexxikon, Inc	Compostos que modulam quinase e composição farmacêutica compreendendo os mesmos
WO2010089580A1 (en)	2009-02-06	2010-08-12	Astrazeneca Ab	Use of a mct1 inhibitor in the treatment of cancers expressing mct1 over mct4
PL2411397T3 (pl) *	2009-03-23	2013-10-31	Glenmark Pharmaceuticals Sa	Pochodne izotiazolo-pirymidynodionu jako modulatory TRPA1
CA2756535A1 (en) *	2009-03-23	2010-09-30	Glenmark Pharmaceuticals, S.A.	Furopyrimidinedione derivatives as trpa1 modulators
MY160737A (en)	2009-04-03	2017-03-15	Hoffmann La Roche	Propane-i-sulfonic acid {3- [5-(4-chloro-phenyl) -1h -pyrrolo [2, 3-b] pyridine-3-carbonyl] -2,4 difluoro-phenyl} - amide compositions and uses thereof
US8329724B2 (en)	2009-08-03	2012-12-11	Hoffmann-La Roche Inc.	Process for the manufacture of pharmaceutically active compounds
SG10201407129SA (en)	2009-11-06	2014-12-30	Plexxikon Inc	Compounds and methods for kinase modulation, and indications therefor
CN103517710B (zh)	2011-02-07	2017-05-31	普莱希科公司	用于激酶调节的化合物
TWI558702B (zh)	2011-02-21	2016-11-21	普雷辛肯公司	醫藥活性物質的固態形式
US9296728B2 (en)	2012-01-20	2016-03-29	Regents Of The University Of Minnesota	Therapeutic compounds
WO2013112881A1 (en)	2012-01-27	2013-08-01	Thomas Jefferson University	Mct protein inhibitor-related prognostic and therapeutic methods
US9150570B2 (en)	2012-05-31	2015-10-06	Plexxikon Inc.	Synthesis of heterocyclic compounds
EP2986290A4 (en)	2013-04-19	2017-01-04	Thomas Jefferson University	Caveolin-1 related methods for treating glioblastoma with temozolomide
EP3060562B1 (en) *	2013-10-21	2021-07-28	Genosco	Substituted pyrimidine compounds and their use as syk inhibitors
JP6725519B2 (ja) *	2015-01-22	2020-07-22	ザスクリプスリサーチインスティテュート	複素環式のモノカルボン酸トランスポータ阻害薬
UY36586A (es) *	2015-03-26	2016-10-31	Bayer Pharma AG	Heterociclilmetiltienouracilos y uso de los mismos
KR101730536B1 (ko) *	2016-03-17	2017-05-02	주식회사 골프존	스크린 골프 시스템에서 구현되는 컨텐츠 전송 서비스 방법, 컨텐츠 전송 서비스를 위한 모바일 단말기의 제어방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록매체
KR101712836B1 (ko) *	2016-03-17	2017-03-22	주식회사 골프존	가상 골프 시뮬레이션 장치, 가상 골프를 위한 영상 구현 방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록 매체
KR101712838B1 (ko) *	2016-03-17	2017-03-07	주식회사 골프존	가상 골프 시뮬레이션 장치, 가상 골프를 위한 영상 구현 방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록 매체
TWI823932B (zh) *	2018-05-11	2023-12-01	中國大陸商迪哲（江蘇）醫藥有限公司	三唑并嘧啶化合物及其在治療癌症中之用途
CN119080799B (zh) *	2024-09-27	2025-12-05	山东大学	一种n-羟基噻吩并嘧啶二酮类衍生物及其制备方法与应用

Family Cites Families (11)

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US738495A (en) *	1902-12-26	1903-09-08	William E Sherwood	Thill-coupling.
US6469014B1 (en) *	1997-05-28	2002-10-22	Astrazeneca Ab	Thieno[2,3-d] pyrimidinediones, their preparation and use in therapy
SE9702001D0 (sv)	1997-05-28	1997-05-28	Astra Pharma Prod	Novel compounds
EP1036076B1 (en)	1997-12-05	2002-09-04	AstraZeneca UK Limited	Novel compounds
US6232320B1 (en)	1998-06-04	2001-05-15	Abbott Laboratories	Cell adhesion-inhibiting antiinflammatory compounds
CA2339664A1 (en) *	1998-08-28	2000-03-09	Astrazeneca Ab	Thieno{2,3,-d}pyrimidinedione derivatives and their use as immunosuppressants
WO2001083489A1 (en) *	2000-05-04	2001-11-08	Astrazeneca Ab	THIENO[2,3-d]PYRIMIDINEDIONES AND THEIR USE AS PHARMACEUTICALS
GB0117583D0 (en)	2001-07-19	2001-09-12	Astrazeneca Ab	Novel compounds
GB0118479D0 (en)	2001-07-28	2001-09-19	Astrazeneca Ab	Novel compounds
PL378221A1 (pl)	2003-01-17	2006-03-20	Astrazeneca Ab	Tienopirydazynony i ich zastosowanie w modulacji choroby autoimmunologicznej
SE0300120D0 (sv)	2003-01-17	2003-01-17	Astrazeneca Ab	Novel compounds

2003
- 2003-01-17 SE SE0300119A patent/SE0300119D0/xx unknown
2004
- 2004-01-15 BR BRPI0406801A patent/BRPI0406801B8/pt not_active IP Right Cessation
- 2004-01-15 KR KR1020117022785A patent/KR20110125256A/ko not_active Withdrawn
- 2004-01-15 CN CNB2004800071073A patent/CN100334093C/zh not_active Expired - Fee Related
- 2004-01-15 UA UAA200506377A patent/UA81788C2/uk unknown
- 2004-01-15 KR KR1020057013126A patent/KR101107486B1/ko not_active Expired - Fee Related
- 2004-01-15 WO PCT/SE2004/000052 patent/WO2004065394A1/en not_active Ceased
- 2004-01-15 JP JP2006500750A patent/JP4519121B2/ja not_active Expired - Fee Related
- 2004-01-15 CA CA2512441A patent/CA2512441C/en not_active Expired - Lifetime
- 2004-01-15 EP EP04702477A patent/EP1587812B1/en not_active Expired - Lifetime
- 2004-01-15 ES ES04702477T patent/ES2270337T3/es not_active Expired - Lifetime
- 2004-01-15 MX MXPA05007496A patent/MXPA05007496A/es active IP Right Grant
- 2004-01-15 NZ NZ541217A patent/NZ541217A/en not_active IP Right Cessation
- 2004-01-15 RU RU2005121494/04A patent/RU2331647C2/ru not_active IP Right Cessation
- 2004-01-15 AU AU2004206012A patent/AU2004206012B2/en not_active Ceased
- 2004-01-15 PL PL378222A patent/PL214682B1/pl unknown
- 2004-01-15 US US10/542,197 patent/US7384951B2/en not_active Expired - Lifetime
- 2004-01-15 DE DE602004001857T patent/DE602004001857T2/de not_active Expired - Lifetime
- 2004-01-15 AT AT04702477T patent/ATE335748T1/de not_active IP Right Cessation
2005
- 2005-06-23 IL IL169370A patent/IL169370A/en active IP Right Grant
- 2005-07-01 ZA ZA2005/05364A patent/ZA200505364B/en unknown
- 2005-07-12 EG EGNA2005000380 patent/EG25613A/xx active
- 2005-07-29 IS IS7965A patent/IS2376B/is unknown
- 2005-08-15 NO NO20053826A patent/NO333702B1/no not_active IP Right Cessation
2008
- 2008-05-05 US US12/115,171 patent/US20080214579A1/en not_active Abandoned

Also Published As

Publication number	Publication date
JP4519121B2 (ja)	2010-08-04
JP2006516974A (ja)	2006-07-13
RU2005121494A (ru)	2006-02-10
DE602004001857T2 (de)	2007-05-24
AU2004206012B2 (en)	2007-06-14
AU2004206012A1 (en)	2004-08-05
IS7965A (is)	2005-07-29
NO20053826D0 (no)	2005-08-15
WO2004065394A1 (en)	2004-08-05
NO20053826L (no)	2005-10-17
MXPA05007496A (es)	2005-09-21
IL169370A (en)	2011-05-31
DE602004001857D1 (de)	2006-09-21
CA2512441A1 (en)	2004-08-05
UA81788C2 (uk)	2008-02-11
KR20110125256A (ko)	2011-11-18
EG25613A (en)	2012-03-22
NO333702B1 (no)	2013-08-26
CA2512441C (en)	2012-01-03
RU2331647C2 (ru)	2008-08-20
IL169370A0 (en)	2007-07-04
US7384951B2 (en)	2008-06-10
US20080214579A1 (en)	2008-09-04
ES2270337T3 (es)	2007-04-01
ATE335748T1 (de)	2006-09-15
CN1761672A (zh)	2006-04-19
KR101107486B1 (ko)	2012-01-19
NZ541217A (en)	2008-05-30
HK1081959A1 (en)	2006-05-26
CN100334093C (zh)	2007-08-29
BRPI0406801B8 (pt)	2021-05-25
ZA200505364B (en)	2006-09-27
BRPI0406801A (pt)	2006-01-17
KR20050092760A (ko)	2005-09-22
PL214682B1 (pl)	2013-09-30
BRPI0406801B1 (pt)	2018-04-03
PL378222A1 (pl)	2006-03-20
EP1587812B1 (en)	2006-08-09
EP1587812A1 (en)	2005-10-26
US20060052400A1 (en)	2006-03-09
SE0300119D0 (sv)	2003-01-17

Publication	Publication Date	Title
IS7965A (is)	2005-07-29	Þíenópýrimidíndíón og notkun þeirra í breytingu ásjálfsnæmissjúkdómi
SE0301700D0 (sv)	2003-06-10	Novel compounds
NO20070224L (no)	2007-04-02	2-karbamid-4-fenyltiazolderivater, fremstilling og terapeutisk anvendelse derav
SE0200920D0 (sv)	2002-03-25	Novel compounds
PT1263725E (pt)	2005-02-28	Novos compostos
IS6658A (is)	2002-12-17	Ný efnasambönd
SE0302139D0 (sv)	2003-07-28	Novel compounds
TW200613243A (en)	2006-05-01	Novel compounds
UA84208C2 (en)	2008-09-25	Tetraazabenzo(e)azulene derivatives and analogs thereof
SE0300480D0 (sv)	2003-02-21	Novel compounds
WO2003086306A3 (en)	2004-02-19	5ht2c receptor modulators
GB0112348D0 (en)	2001-07-11	Compounds
EA200401526A1 (ru)	2005-04-28	Новые соединения и их применение
SE0401762D0 (sv)	2004-07-05	Novel compounds
DK1517890T3 (da)	2008-11-10	Kationisk substituerede diphenylazetidinoner, fremgangsmåde til deres fremstilling, lægemidler indeholdende disse forbindelser og deres anvendelse
TW200604197A (en)	2006-02-01	New compounds
SE0402925D0 (sv)	2004-11-30	Novel Compounds
SE0101038D0 (sv)	2001-03-23	Novel compounds
SE0303280D0 (sv)	2003-12-05	Novel compounds
SE0401763D0 (sv)	2004-07-05	Compounds
EA200600992A1 (ru)	2006-10-27	Амиды тиазолидинона, амиды тиазолидинкарбоновой кислоты, способы их получения и их применение
DK1727817T3 (da)	2011-01-10	Azabicyclooctan-3-onderivativer og anvendelse heraf
SE0302755D0 (sv)	2003-10-17	Novel compounds
SE0202693D0 (sv)	2002-09-11	Compounds
IL172538A0 (en)	2006-04-10	Depsipeptide compounds, pharmaceutical compositions containing the same and processes for the preparation thereof