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HUE038620T2 - Eljárások RPE sejtek elõállítására - Google Patents

Eljárások RPE sejtek elõállítására

Info

Publication number
HUE038620T2
HUE038620T2 HUE13844534A HUE13844534A HUE038620T2 HU E038620 T2 HUE038620 T2 HU E038620T2 HU E13844534 A HUE13844534 A HU E13844534A HU E13844534 A HUE13844534 A HU E13844534A HU E038620 T2 HUE038620 T2 HU E038620T2
Authority
HU
Hungary
Prior art keywords
methods
rpe cells
producing rpe
producing
cells
Prior art date
Application number
HUE13844534A
Other languages
English (en)
Hungarian (hu)
Inventor
Outi Hovatta
Karl Tryggvason
Original Assignee
Biolamina Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biolamina Ab filed Critical Biolamina Ab
Publication of HUE038620T2 publication Critical patent/HUE038620T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0618Cells of the nervous system
    • C12N5/0621Eye cells, e.g. cornea, iris pigmented cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • C12N5/0056Xeno-free medium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components
    • C12N2500/92Medium free of human- or animal-derived components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/98Xeno-free medium and culture conditions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/115Basic fibroblast growth factor (bFGF, FGF-2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins
    • C12N2533/52Fibronectin; Laminin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
HUE13844534A 2012-12-03 2013-12-03 Eljárások RPE sejtek elõállítására HUE038620T2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261732764P 2012-12-03 2012-12-03
US201261733314P 2012-12-04 2012-12-04

Publications (1)

Publication Number Publication Date
HUE038620T2 true HUE038620T2 (hu) 2018-10-29

Family

ID=50439420

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE13844534A HUE038620T2 (hu) 2012-12-03 2013-12-03 Eljárások RPE sejtek elõállítására

Country Status (12)

Country Link
US (3) US10889801B2 (fr)
EP (1) EP2925856B1 (fr)
DK (1) DK2925856T3 (fr)
ES (1) ES2666668T3 (fr)
HR (1) HRP20180418T1 (fr)
HU (1) HUE038620T2 (fr)
PL (1) PL2925856T3 (fr)
PT (1) PT2925856T (fr)
RS (1) RS57257B1 (fr)
SI (1) SI2925856T1 (fr)
TR (1) TR201807259T4 (fr)
WO (1) WO2014087244A2 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL281453B (en) 2009-11-17 2022-07-01 Astellas Inst For Regenerative Medicine Methods for preparing human rpe cells and pharmaceutical preparations of human rpe cells
RS57257B1 (sr) * 2012-12-03 2018-08-31 Biolamina Ab Metodi proizvodnje rpe ćelija
CN105814195A (zh) 2013-11-27 2016-07-27 京都府公立大学法人 层粘连蛋白应用于角膜内皮细胞培养
WO2016067628A1 (fr) 2014-10-31 2016-05-06 京都府公立大学法人 Nouveau traitement de la cornée employant de la laminine
US11918630B2 (en) 2014-10-31 2024-03-05 Kyoto Prefectural Public University Corporation Treatment of retina and nerve using laminin
CN107406830A (zh) 2014-12-30 2017-11-28 细胞治疗神经科学有限公司 Rpe细胞群和制备它们的方法
DK3331994T3 (da) 2015-08-05 2022-11-21 Cell Cure Neurosciences Ltd Fremstilling af retinale pigmentepitelceller
ES3018474T3 (es) 2015-10-26 2025-05-16 Cell Cure Neurosciences Ltd Preparación de células del epitelio pigmentario de la retina
CA3028613A1 (fr) * 2016-06-30 2018-01-04 Sumitomo Dainippon Pharma Co., Ltd. Milieu de transplantation
WO2019078781A1 (fr) * 2017-10-17 2019-04-25 National University Of Singapore Systèmes et méthodes pour la production de progéniteurs de photorécepteurs
CN119410584A (zh) * 2018-06-20 2025-02-11 拜奥拉米那公司 用于产生视网膜色素上皮细胞的方法和组合物
JPWO2023176906A1 (fr) 2022-03-16 2023-09-21
JPWO2024172043A1 (fr) 2023-02-14 2024-08-22

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10829733B2 (en) * 2007-01-04 2020-11-10 Biolamina Ab Composition and method for enabling proliferation of pluripotent human stem cells
KR101966033B1 (ko) * 2010-12-17 2019-04-04 바이오라미나 에이비 재조합 라미닌-521
US9850463B2 (en) * 2012-02-01 2017-12-26 The Regents Of The University Of California Methods of culturing retinal pigmented epithelium cells, including xeno-free production, RPE enrichment, and cryopreservation
RS57257B1 (sr) * 2012-12-03 2018-08-31 Biolamina Ab Metodi proizvodnje rpe ćelija

Also Published As

Publication number Publication date
PT2925856T (pt) 2018-06-15
US10889801B2 (en) 2021-01-12
EP2925856A2 (fr) 2015-10-07
ES2666668T3 (es) 2018-05-07
US20150299653A1 (en) 2015-10-22
HRP20180418T1 (hr) 2018-04-20
DK2925856T3 (en) 2018-05-07
US12195757B2 (en) 2025-01-14
US20240228955A9 (en) 2024-07-11
WO2014087244A3 (fr) 2014-08-21
US20210139848A1 (en) 2021-05-13
US11767509B2 (en) 2023-09-26
PL2925856T3 (pl) 2018-07-31
US20240132838A1 (en) 2024-04-25
TR201807259T4 (tr) 2018-06-21
EP2925856B1 (fr) 2018-03-07
SI2925856T1 (en) 2018-06-29
RS57257B1 (sr) 2018-08-31
WO2014087244A2 (fr) 2014-06-12

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