GR3036571T3 - Pharmaceutical compositions for hardly soluble active substances - Google Patents

Pharmaceutical compositions for hardly soluble active substances

Info

Publication number: GR3036571T3
Authority: GR; Greece
Prior art keywords: active agent; component; pharmaceutical compositions; active substances; hardly soluble
Prior art date: 1993-07-08

Application number

GR20010401428T

Other languages

English (en)

Inventor

Ulrich Posanski

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-07-08

Filing date

2001-09-10

Publication date

2001-12-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6492300&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR3036571(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-09-10 Application filed by Sandoz Ag filed Critical Sandoz Ag

2001-12-31 Publication of GR3036571T3 publication Critical patent/GR3036571T3/el

Links

239000013543 active substance Substances 0.000 title abstract 5
239000008194 pharmaceutical composition Substances 0.000 title 1
-1 fatty acid ester Chemical class 0.000 abstract 3
235000014113 dietary fatty acids Nutrition 0.000 abstract 2
229930195729 fatty acid Natural products 0.000 abstract 2
239000000194 fatty acid Substances 0.000 abstract 2
AGBQKNBQESQNJD-UHFFFAOYSA-N lipoic acid Chemical compound OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 abstract 2
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
UIAGMCDKSXEBJQ-IBGZPJMESA-N 3-o-(2-methoxyethyl) 5-o-propan-2-yl (4s)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Chemical compound COCCOC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)C)[C@H]1C1=CC=CC([N+]([O-])=O)=C1 UIAGMCDKSXEBJQ-IBGZPJMESA-N 0.000 abstract 1
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 1
229930105110 Cyclosporin A Natural products 0.000 abstract 1
108010036949 Cyclosporine Proteins 0.000 abstract 1
HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 abstract 1
QJJXYPPXXYFBGM-LFZNUXCKSA-N Tacrolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1\C=C(/C)[C@@H]1[C@H](C)[C@@H](O)CC(=O)[C@H](CC=C)/C=C(C)/C[C@H](C)C[C@H](OC)[C@H]([C@H](C[C@H]2C)OC)O[C@@]2(O)C(=O)C(=O)N2CCCC[C@H]2C(=O)O1 QJJXYPPXXYFBGM-LFZNUXCKSA-N 0.000 abstract 1
229960001265 ciclosporin Drugs 0.000 abstract 1
229930182912 cyclosporin Natural products 0.000 abstract 1
239000012153 distilled water Substances 0.000 abstract 1
VJJPUSNTGOMMGY-MRVIYFEKSA-N etoposide Chemical compound COC1=C(O)C(OC)=CC([C@@H]2C3=CC=4OCOC=4C=C3[C@@H](O[C@H]3[C@@H]([C@@H](O)[C@@H]4O[C@H](C)OC[C@H]4O3)O)[C@@H]3[C@@H]2C(OC3)=O)=C1 VJJPUSNTGOMMGY-MRVIYFEKSA-N 0.000 abstract 1
229960005420 etoposide Drugs 0.000 abstract 1
229960001680 ibuprofen Drugs 0.000 abstract 1
235000019136 lipoic acid Nutrition 0.000 abstract 1
HYIMSNHJOBLJNT-UHFFFAOYSA-N nifedipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1[N+]([O-])=O HYIMSNHJOBLJNT-UHFFFAOYSA-N 0.000 abstract 1
229960001597 nifedipine Drugs 0.000 abstract 1
229960000715 nimodipine Drugs 0.000 abstract 1
239000002736 nonionic surfactant Substances 0.000 abstract 1
ZAHRKKWIAAJSAO-UHFFFAOYSA-N rapamycin Natural products COCC(O)C(=C/C(C)C(=O)CC(OC(=O)C1CCCCN1C(=O)C(=O)C2(O)OC(CC(OC)C(=CC=CC=CC(C)CC(C)C(=O)C)C)CCC2C)C(C)CC3CCC(O)C(C3)OC)C ZAHRKKWIAAJSAO-UHFFFAOYSA-N 0.000 abstract 1
229960002930 sirolimus Drugs 0.000 abstract 1
QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 abstract 1
229960001967 tacrolimus Drugs 0.000 abstract 1
QJJXYPPXXYFBGM-SHYZHZOCSA-N tacrolimus Natural products CO[C@H]1C[C@H](CC[C@@H]1O)C=C(C)[C@H]2OC(=O)[C@H]3CCCCN3C(=O)C(=O)[C@@]4(O)O[C@@H]([C@H](C[C@H]4C)OC)[C@@H](C[C@H](C)CC(=C[C@@H](CC=C)C(=O)C[C@H](O)[C@H]2C)C)OC QJJXYPPXXYFBGM-SHYZHZOCSA-N 0.000 abstract 1
229960002663 thioctic acid Drugs 0.000 abstract 1
UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Oil, Petroleum & Natural Gas (AREA)
Chemical Kinetics & Catalysis (AREA)
Transplantation (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

GR20010401428T 1993-07-08 2001-09-10 Pharmaceutical compositions for hardly soluble active substances GR3036571T3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE4322826A DE4322826A1 (de)	1993-07-08	1993-07-08	Pharmazeutisches Präparat
PCT/EP1994/002238 WO1995001785A1 (de)	1993-07-08	1994-07-08	Pharmazeutische präparate für schwerlösliche wirkstoffe

Publications (1)

Publication Number	Publication Date
GR3036571T3 true GR3036571T3 (en)	2001-12-31

Family

ID=6492300

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GR20010401428T GR3036571T3 (en)	1993-07-08	2001-09-10	Pharmaceutical compositions for hardly soluble active substances

Country Status (24)

Country	Link
EP (3)	EP0710103B1 (el)
JP (4)	JPH08512301A (el)
KR (2)	KR100359044B1 (el)
CN (2)	CN1313154C (el)
AT (3)	ATE172876T1 (el)
AU (2)	AU689486B2 (el)
BR (1)	BR9407002A (el)
CA (2)	CA2166204C (el)
CY (2)	CY2308B1 (el)
CZ (1)	CZ291401B6 (el)
DE (6)	DE4322826A1 (el)
DK (3)	DK1092429T3 (el)
ES (3)	ES2218046T3 (el)
FI (2)	FI116197B (el)
GR (1)	GR3036571T3 (el)
HU (2)	HU223073B1 (el)
NO (2)	NO306929B1 (el)
NZ (2)	NZ269808A (el)
PL (1)	PL179717B1 (el)
PT (2)	PT1092429E (el)
RU (1)	RU2140291C1 (el)
SI (1)	SI1092429T1 (el)
SK (1)	SK280615B6 (el)
WO (2)	WO1995001786A1 (el)

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Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1132518A (en) *	1965-02-18	1968-11-06	Richardson Merrell Inc	Medicinal composition
IT1090703B (it) *	1976-12-03	1985-06-26	Scherer Ltd R P	Perfezionamento nelle composizioni utili quali veicolo per farmaci
GB8903804D0 (en) *	1989-02-20	1989-04-05	Sandoz Ltd	Improvements in or relating to organic compounds
GB8630273D0 (en) *	1986-12-18	1987-01-28	Til Medical Ltd	Pharmaceutical delivery systems
DE68900991D1 (de) *	1988-01-29	1992-04-23	Sankyo Co	Cyclosporin-zusammensetzungen.
GB2222770B (en) *	1988-09-16	1992-07-29	Sandoz Ltd	Pharmaceutical compositions containing cyclosporins
WO1990014837A1 (en) *	1989-05-25	1990-12-13	Chiron Corporation	Adjuvant formulation comprising a submicron oil droplet emulsion
DK0448091T3 (da) *	1990-03-23	1999-05-03	Yoshitomi Pharmaceutical	Farmaceutisk præparat indeholdende et i ringe grad vandopløseligt medikament
GB9113872D0 (en) *	1991-06-27	1991-08-14	Sandoz Ag	Improvements in or relating to organic compounds
JPH0525037A (ja) *	1991-07-01	1993-02-02	Upjohn Co:The	経口投与酵素感受性腸溶製剤
RU2053764C1 (ru) *	1991-07-19	1996-02-10	Эгиш Дьедьсердьяр	Мягкая желатиновая капсула и способ ее получения
DE4322826A1 (de) *	1993-07-08	1995-01-12	Galenik Labor Freiburg Gmbh	Pharmazeutisches Präparat

1993
- 1993-07-08 DE DE4322826A patent/DE4322826A1/de not_active Withdrawn
1994
- 1994-07-08 SI SI9430465T patent/SI1092429T1/xx unknown
- 1994-07-08 AU AU73457/94A patent/AU689486B2/en not_active Expired
- 1994-07-08 AT AT94923715T patent/ATE172876T1/de not_active IP Right Cessation
- 1994-07-08 EP EP94922269A patent/EP0710103B1/de not_active Expired - Lifetime
- 1994-07-08 DK DK00122248T patent/DK1092429T3/da active
- 1994-07-08 CN CNB031522890A patent/CN1313154C/zh not_active Expired - Lifetime
- 1994-07-08 CZ CZ199645A patent/CZ291401B6/cs not_active IP Right Cessation
- 1994-07-08 JP JP7503830A patent/JPH08512301A/ja active Pending
- 1994-07-08 ES ES00122248T patent/ES2218046T3/es not_active Expired - Lifetime
- 1994-07-08 EP EP00122248A patent/EP1092429B1/de not_active Expired - Lifetime
- 1994-07-08 DE DE4494850T patent/DE4494850D2/de not_active Expired - Fee Related
- 1994-07-08 DK DK94923715T patent/DK0710104T3/da active
- 1994-07-08 JP JP7503833A patent/JPH08512303A/ja active Pending
- 1994-07-08 DK DK94922269T patent/DK0710103T3/da active
- 1994-07-08 HU HU9503868A patent/HU223073B1/hu active IP Right Grant
- 1994-07-08 KR KR1019960700042A patent/KR100359044B1/ko not_active Expired - Fee Related
- 1994-07-08 AT AT00122248T patent/ATE261720T1/de active
- 1994-07-08 BR BR9407002A patent/BR9407002A/pt not_active Application Discontinuation
- 1994-07-08 EP EP94923715A patent/EP0710104B1/de not_active Expired - Lifetime
- 1994-07-08 WO PCT/EP1994/002248 patent/WO1995001786A1/de not_active Ceased
- 1994-07-08 CA CA002166204A patent/CA2166204C/en not_active Expired - Fee Related
- 1994-07-08 CA CA002164100A patent/CA2164100A1/en not_active Abandoned
- 1994-07-08 NZ NZ269808A patent/NZ269808A/xx not_active IP Right Cessation
- 1994-07-08 HU HU9503965A patent/HU228127B1/hu not_active IP Right Cessation
- 1994-07-08 AT AT94922269T patent/ATE201985T1/de active
- 1994-07-08 RU RU96102012A patent/RU2140291C1/ru active
- 1994-07-08 DE DE59407239T patent/DE59407239D1/de not_active Expired - Fee Related
- 1994-07-08 CN CN94192714A patent/CN1121853C/zh not_active Expired - Lifetime
- 1994-07-08 SK SK19-96A patent/SK280615B6/sk not_active IP Right Cessation
- 1994-07-08 PL PL94312255A patent/PL179717B1/pl unknown
- 1994-07-08 AU AU73850/94A patent/AU7385094A/en not_active Abandoned
- 1994-07-08 PT PT00122248T patent/PT1092429E/pt unknown
- 1994-07-08 KR KR1019960700026A patent/KR100386533B1/ko not_active Expired - Lifetime
- 1994-07-08 DE DE59409787T patent/DE59409787D1/de not_active Expired - Lifetime
- 1994-07-08 DE DE59410365T patent/DE59410365D1/de not_active Expired - Lifetime
- 1994-07-08 PT PT94922269T patent/PT710103E/pt unknown
- 1994-07-08 ES ES94922269T patent/ES2159564T3/es not_active Expired - Lifetime
- 1994-07-08 ES ES94923715T patent/ES2124420T3/es not_active Expired - Lifetime
- 1994-07-08 DE DE4494851T patent/DE4494851D2/de not_active Expired - Fee Related
- 1994-07-08 WO PCT/EP1994/002238 patent/WO1995001785A1/de not_active Ceased
- 1994-07-08 NZ NZ269552A patent/NZ269552A/xx not_active IP Right Cessation
1996
- 1996-01-03 FI FI960032A patent/FI116197B/fi active IP Right Grant
- 1996-01-04 FI FI960042A patent/FI116714B/fi not_active IP Right Cessation
- 1996-01-05 NO NO960062A patent/NO306929B1/no not_active IP Right Cessation
- 1996-01-05 NO NO960069A patent/NO306763B1/no not_active IP Right Cessation
2001
- 2001-09-10 GR GR20010401428T patent/GR3036571T3/el unknown
2002
- 2002-12-12 CY CY0200068A patent/CY2308B1/xx unknown
2005
- 2005-09-08 CY CY0500049A patent/CY2604B2/el unknown
2009
- 2009-02-04 JP JP2009023837A patent/JP2009138008A/ja not_active Withdrawn
2011
- 2011-03-24 JP JP2011066324A patent/JP2011153150A/ja active Pending

Also Published As

Publication number	Publication date
BR9407002A (pt)	1996-09-03
DE4494851D2 (de)	1996-12-19
CZ291401B6 (cs)	2003-03-12
CZ4596A3 (en)	1996-04-17
FI960042A0 (fi)	1996-01-04
EP0710104A1 (de)	1996-05-08
WO1995001786A1 (de)	1995-01-19
EP1092429B1 (de)	2004-03-17
NO960062D0 (no)	1996-01-05
DE4322826A1 (de)	1995-01-12
NO960062L (no)	1996-01-05
JP2009138008A (ja)	2009-06-25
EP0710103A1 (de)	1996-05-08
EP0710103B1 (de)	2001-06-13
PT710103E (pt)	2001-11-30
CN1121853C (zh)	2003-09-24
HUT73661A (en)	1996-09-30
CN1128495A (zh)	1996-08-07
HU9503965D0 (en)	1996-03-28
EP0710104B1 (de)	1998-11-04
FI960042L (fi)	1996-01-04
HU223073B1 (hu)	2004-03-01
AU7345794A (en)	1995-02-06
ATE201985T1 (de)	2001-06-15
DE59410365D1 (de)	2004-04-22
ES2218046T3 (es)	2004-11-16
CY2604B2 (el)	2010-04-28
RU2140291C1 (ru)	1999-10-27
AU689486B2 (en)	1998-04-02
SK280615B6 (sk)	2000-05-16
NO960069D0 (no)	1996-01-05
KR100359044B1 (ko)	2003-02-05
NZ269808A (en)	1996-07-26
DE59407239D1 (de)	1998-12-10
HU228127B1 (en)	2012-12-28
CN1313154C (zh)	2007-05-02
NZ269552A (en)	1996-07-26
DE59409787D1 (de)	2001-07-19
ES2124420T3 (es)	1999-02-01
DK1092429T3 (da)	2004-07-19
HUT73427A (en)	1996-07-29
SK1996A3 (en)	1997-04-09
PT1092429E (pt)	2004-08-31
NO306929B1 (no)	2000-01-17
ATE172876T1 (de)	1998-11-15
PL312255A1 (en)	1996-04-01
JPH08512303A (ja)	1996-12-24
FI960032L (fi)	1996-02-09
DE4494850D2 (de)	1996-08-22
SI1092429T1 (en)	2004-08-31
KR100386533B1 (ko)	2003-08-21
JPH08512301A (ja)	1996-12-24
CA2166204A1 (en)	1995-01-19
NO960069L (no)	1996-01-05
EP1092429A1 (de)	2001-04-18
ES2159564T3 (es)	2001-10-16
WO1995001785A1 (de)	1995-01-19
PL179717B1 (pl)	2000-10-31
JP2011153150A (ja)	2011-08-11
CA2166204C (en)	2009-04-14
FI960032A0 (fi)	1996-01-03
NO306763B1 (no)	1999-12-20
DK0710103T3 (da)	2001-09-24
AU7385094A (en)	1995-02-06
HU9503868D0 (en)	1996-02-28
CN1496743A (zh)	2004-05-19
FI116197B (fi)	2005-10-14
DK0710104T3 (da)	1999-07-19
CY2308B1 (en)	2003-11-14
ATE261720T1 (de)	2004-04-15
FI116714B (fi)	2006-02-15
CA2164100A1 (en)	1995-01-19

Publication	Publication Date	Title
GR3036571T3 (en)	2001-12-31	Pharmaceutical compositions for hardly soluble active substances
TR199501321A2 (tr)	1996-06-21	Farmasötik bilesimler.
NZ512287A (en)	2002-12-20	Pharmaceutical compositions comprising a lipophilic drug in a propylene glycol ester of a higher fatty acid carrier, where 60% of the ester is a monoester
ATE265847T1 (de)	2004-05-15	Selbstemulgierbare formulierung enthaltend lipophile verbindungen
EA200200415A1 (ru)	2002-10-31	Композиция фармацевтического носителя
EP0913390A3 (en)	2001-02-07	Nonionic surfactant
KR960033448A (ko)	1996-10-22	도코사헥사엔산(dha) 함유 수용액 조성물