FR2573427B1 - FLAVOLIGNAN DERIVATIVES, METHODS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS - Google Patents

FLAVOLIGNAN DERIVATIVES, METHODS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS

Info

Publication number: FR2573427B1
Authority: FR; France
Prior art keywords: flavolignan; derivatives; compounds; preparation; methods
Prior art date: 1984-11-22
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

FR858517321A

Other languages

French (fr)

Other versions

FR2573427A1 (en

Inventor

Reinhard Braatz

Klaus Gorler

Gunter Halbach

Hartwig Soicke

Karlheinz Schmidt

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Madaus Holding GmbH

Madaus GmbH

Original Assignee

Dr Madaus GmbH and Co

Madaus GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-11-22

Filing date

1985-11-22

Publication date

1989-03-10

1985-11-22 Application filed by Dr Madaus GmbH and Co, Madaus GmbH filed Critical Dr Madaus GmbH and Co

1986-05-23 Publication of FR2573427A1 publication Critical patent/FR2573427A1/en

1989-03-10 Application granted granted Critical

1989-03-10 Publication of FR2573427B1 publication Critical patent/FR2573427B1/en

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Toxicology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Dermatology (AREA)
Gastroenterology & Hepatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Silicon Compounds (AREA)

FR858517321A 1984-11-22 1985-11-22 FLAVOLIGNAN DERIVATIVES, METHODS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS Expired FR2573427B1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19843442639 DE3442639A1 (en)	1984-11-22	1984-11-22	FLAVOLIGNANE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS

Publications (2)

Publication Number	Publication Date
FR2573427A1 FR2573427A1 (en)	1986-05-23
FR2573427B1 true FR2573427B1 (en)	1989-03-10

Family

ID=6250903

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FR858517321A Expired FR2573427B1 (en)	1984-11-22	1985-11-22	FLAVOLIGNAN DERIVATIVES, METHODS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS

Country Status (29)

Country	Link
JP (1)	JPS61143377A (en)
KR (1)	KR870001020B1 (en)
AR (1)	AR240931A1 (en)
AT (1)	AT393268B (en)
BE (1)	BE903693A (en)
CA (1)	CA1337124C (en)
CH (1)	CH659473A5 (en)
CS (1)	CS273610B2 (en)
DD (1)	DD259191A1 (en)
DE (1)	DE3442639A1 (en)
DK (1)	DK164865C (en)
EG (1)	EG19424A (en)
ES (1)	ES8609311A1 (en)
FI (1)	FI84064C (en)
FR (1)	FR2573427B1 (en)
GB (1)	GB2167414B (en)
HU (1)	HU195503B (en)
IE (1)	IE58791B1 (en)
IT (1)	IT1190426B (en)
LU (1)	LU86163A1 (en)
MX (1)	MX168415B (en)
NL (1)	NL192387C (en)
NO (1)	NO160205C (en)
PL (1)	PL146890B1 (en)
PT (1)	PT81532B (en)
SE (1)	SE465676B (en)
SU (1)	SU1436875A3 (en)
YU (1)	YU43689B (en)
ZA (1)	ZA858951B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8716918D0 (en) *	1987-07-17	1987-08-26	Inverni Della Beffa Spa	Soluble derivatives of silybin
US5262439A (en) *	1992-04-30	1993-11-16	The Regents Of The University Of California	Soluble analogs of probucol
CA2601028C (en) *	2005-03-11	2014-05-27	Howard Florey Institute Of Experimental Physiology And Medecine	Flavonoid compounds and uses thereof
CN102300570B (en) *	2007-11-15	2015-01-14	马道斯有限责任公司	Components of silibinin for the treatment of hepatitis
RU2482844C2 (en) *	2007-11-15	2013-05-27	Мадаус Гмбх	Silibilin component for treating hepatitis
PT2430017T (en)	2009-05-14	2016-10-12	Madaus Gmbh	A method for preparing amorphous silibinin
CA2877329C (en)	2012-07-05	2020-01-07	Nutramax Laboratories, Inc.	Compositions comprising sulforaphane or a sulforaphane precursor and magnesium
CN103172622B (en) *	2013-02-22	2015-11-04	西安安健药业有限公司	The active isomer of silybin bis-bias succinate
CN103193768B (en) *	2013-02-22	2016-03-30	西安安健药业有限公司	The silybin bis-bias succinate isomer for the treatment of hepatopathy
CN103113359B (en) *	2013-02-22	2016-01-06	西安安健药业有限公司	Silybin bis-bias succinate and pharmaceutical salts thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1963318A1 (en) *	1969-12-17	1971-06-24	Schwabe Willmar Gmbh & Co	Silybin esters with hepotoprotactant acti- - vity

1984
- 1984-11-22 DE DE19843442639 patent/DE3442639A1/en active Granted
1985
- 1985-11-11 IE IE280885A patent/IE58791B1/en not_active IP Right Cessation
- 1985-11-13 LU LU86163A patent/LU86163A1/en unknown
- 1985-11-14 YU YU1786/85A patent/YU43689B/en unknown
- 1985-11-14 AR AR302267A patent/AR240931A1/en active
- 1985-11-15 GB GB08528226A patent/GB2167414B/en not_active Expired
- 1985-11-18 NL NL8503171A patent/NL192387C/en not_active IP Right Cessation
- 1985-11-18 FI FI854535A patent/FI84064C/en not_active IP Right Cessation
- 1985-11-19 CH CH4935/85A patent/CH659473A5/en not_active IP Right Cessation
- 1985-11-19 AT AT3371/85A patent/AT393268B/en not_active IP Right Cessation
- 1985-11-20 CS CS837885A patent/CS273610B2/en unknown
- 1985-11-20 CA CA000495804A patent/CA1337124C/en not_active Expired - Fee Related
- 1985-11-20 SE SE8505487A patent/SE465676B/en not_active IP Right Cessation
- 1985-11-20 DD DD85283042A patent/DD259191A1/en not_active IP Right Cessation
- 1985-11-21 PT PT81532A patent/PT81532B/en not_active IP Right Cessation
- 1985-11-21 ZA ZA858951A patent/ZA858951B/en unknown
- 1985-11-21 DK DK537785A patent/DK164865C/en not_active IP Right Cessation
- 1985-11-21 PL PL1985256374A patent/PL146890B1/en unknown
- 1985-11-21 NO NO854655A patent/NO160205C/en not_active IP Right Cessation
- 1985-11-21 ES ES549116A patent/ES8609311A1/en not_active Expired
- 1985-11-21 EG EG74085A patent/EG19424A/en active
- 1985-11-21 IT IT22932/85A patent/IT1190426B/en active
- 1985-11-21 SU SU853985401A patent/SU1436875A3/en active
- 1985-11-21 HU HU854448A patent/HU195503B/en not_active IP Right Cessation
- 1985-11-22 JP JP60261629A patent/JPS61143377A/en active Granted
- 1985-11-22 FR FR858517321A patent/FR2573427B1/en not_active Expired
- 1985-11-22 KR KR1019850008733A patent/KR870001020B1/en not_active Expired
- 1985-11-22 BE BE2/60850A patent/BE903693A/en not_active IP Right Cessation
- 1985-11-22 MX MX009022A patent/MX168415B/en unknown

Also Published As

Publication number	Publication date
HU195503B (en)	1988-05-30
FR2573427A1 (en)	1986-05-23
NL8503171A (en)	1986-06-16
CH659473A5 (en)	1987-01-30
BE903693A (en)	1986-05-22
EG19424A (en)	1995-02-28
CS837885A2 (en)	1990-08-14
SE8505487D0 (en)	1985-11-20
YU178685A (en)	1988-02-29
DK164865B (en)	1992-08-31
FI854535A0 (en)	1985-11-18
CA1337124C (en)	1995-09-26
ES8609311A1 (en)	1986-09-01
ES549116A0 (en)	1986-09-01
DE3442639A1 (en)	1986-05-22
IE852808L (en)	1986-05-22
CS273610B2 (en)	1991-03-12
DK164865C (en)	1993-01-18
AR240931A1 (en)	1991-03-27
NO160205C (en)	1989-03-22
SU1436875A3 (en)	1988-11-07
GB2167414A (en)	1986-05-29
PL146890B1 (en)	1989-03-31
SE465676B (en)	1991-10-14
KR860004056A (en)	1986-06-16
DK537785A (en)	1986-05-23
YU43689B (en)	1989-10-31
DK537785D0 (en)	1985-11-21
LU86163A1 (en)	1986-03-24
JPS61143377A (en)	1986-07-01
NO160205B (en)	1988-12-12
GB8528226D0 (en)	1985-12-18
NL192387B (en)	1997-03-03
DE3442639C2 (en)	1989-08-10
PL256374A1 (en)	1986-12-02
ZA858951B (en)	1986-08-27
AT393268B (en)	1991-09-25
JPH0432073B2 (en)	1992-05-28
KR870001020B1 (en)	1987-05-23
HUT40114A (en)	1986-11-28
GB2167414B (en)	1989-01-11
FI84064C (en)	1991-10-10
SE8505487L (en)	1986-05-23
MX168415B (en)	1993-05-24
NL192387C (en)	1997-07-04
FI854535A7 (en)	1986-05-23
AR240931A2 (en)	1991-03-27
PT81532A (en)	1985-12-01
PT81532B (en)	1987-11-11
DD259191A1 (en)	1988-08-17
IE58791B1 (en)	1993-11-17
IT1190426B (en)	1988-02-16
IT8522932A0 (en)	1985-11-21
ATA337185A (en)	1991-02-15
NO854655L (en)	1986-05-23
FI84064B (en)	1991-06-28

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Legal Events

Date	Code	Title
1990-05-04	TP	Transmission of property
2002-08-30	ST	Notification of lapse
2002-09-06	ST	Notification of lapse