NO160205C - PROCEDURE FOR THE PREPARATION OF SILIBINE INGREDIENTS. - Google Patents

PROCEDURE FOR THE PREPARATION OF SILIBINE INGREDIENTS.

Info

Publication number: NO160205C
Authority: NO; Norway
Prior art keywords: silibine; ingredients; procedure; preparation; silibine ingredients
Prior art date: 1984-11-22

Application number

NO854655A

Other languages

Norwegian (no)

Other versions

NO160205B (en

NO854655L (en

Inventor

Reinhard Braatz

Klaus Goerler

Guenter Halbach

Hartwig Soicke

Karlheinz Schmidt

Original Assignee

Madaus & Co Dr

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-11-22

Filing date

1985-11-21

Publication date

1989-03-22

1985-11-21 Application filed by Madaus & Co Dr filed Critical Madaus & Co Dr

1986-05-23 Publication of NO854655L publication Critical patent/NO854655L/en

1988-12-12 Publication of NO160205B publication Critical patent/NO160205B/en

1989-03-22 Publication of NO160205C publication Critical patent/NO160205C/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Toxicology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Dermatology (AREA)
Gastroenterology & Hepatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Silicon Compounds (AREA)

NO854655A 1984-11-22 1985-11-21 PROCEDURE FOR THE PREPARATION OF SILIBINE INGREDIENTS. NO160205C (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19843442639 DE3442639A1 (en)	1984-11-22	1984-11-22	FLAVOLIGNANE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS

Publications (3)

Publication Number	Publication Date
NO854655L NO854655L (en)	1986-05-23
NO160205B NO160205B (en)	1988-12-12
NO160205C true NO160205C (en)	1989-03-22

Family

ID=6250903

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO854655A NO160205C (en)	1984-11-22	1985-11-21	PROCEDURE FOR THE PREPARATION OF SILIBINE INGREDIENTS.

Country Status (29)

Country	Link
JP (1)	JPS61143377A (en)
KR (1)	KR870001020B1 (en)
AR (1)	AR240931A1 (en)
AT (1)	AT393268B (en)
BE (1)	BE903693A (en)
CA (1)	CA1337124C (en)
CH (1)	CH659473A5 (en)
CS (1)	CS273610B2 (en)
DD (1)	DD259191A1 (en)
DE (1)	DE3442639A1 (en)
DK (1)	DK164865C (en)
EG (1)	EG19424A (en)
ES (1)	ES8609311A1 (en)
FI (1)	FI84064C (en)
FR (1)	FR2573427B1 (en)
GB (1)	GB2167414B (en)
HU (1)	HU195503B (en)
IE (1)	IE58791B1 (en)
IT (1)	IT1190426B (en)
LU (1)	LU86163A1 (en)
MX (1)	MX168415B (en)
NL (1)	NL192387C (en)
NO (1)	NO160205C (en)
PL (1)	PL146890B1 (en)
PT (1)	PT81532B (en)
SE (1)	SE465676B (en)
SU (1)	SU1436875A3 (en)
YU (1)	YU43689B (en)
ZA (1)	ZA858951B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8716918D0 (en) *	1987-07-17	1987-08-26	Inverni Della Beffa Spa	Soluble derivatives of silybin
US5262439A (en) *	1992-04-30	1993-11-16	The Regents Of The University Of California	Soluble analogs of probucol
CA2601028C (en) *	2005-03-11	2014-05-27	Howard Florey Institute Of Experimental Physiology And Medecine	Flavonoid compounds and uses thereof
CN102300570B (en) *	2007-11-15	2015-01-14	马道斯有限责任公司	Components of silibinin for the treatment of hepatitis
RU2482844C2 (en) *	2007-11-15	2013-05-27	Мадаус Гмбх	Silibilin component for treating hepatitis
PT2430017T (en)	2009-05-14	2016-10-12	Madaus Gmbh	A method for preparing amorphous silibinin
CA2877329C (en)	2012-07-05	2020-01-07	Nutramax Laboratories, Inc.	Compositions comprising sulforaphane or a sulforaphane precursor and magnesium
CN103172622B (en) *	2013-02-22	2015-11-04	西安安健药业有限公司	The active isomer of silybin bis-bias succinate
CN103193768B (en) *	2013-02-22	2016-03-30	西安安健药业有限公司	The silybin bis-bias succinate isomer for the treatment of hepatopathy
CN103113359B (en) *	2013-02-22	2016-01-06	西安安健药业有限公司	Silybin bis-bias succinate and pharmaceutical salts thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1963318A1 (en) *	1969-12-17	1971-06-24	Schwabe Willmar Gmbh & Co	Silybin esters with hepotoprotactant acti- - vity

1984
- 1984-11-22 DE DE19843442639 patent/DE3442639A1/en active Granted
1985
- 1985-11-11 IE IE280885A patent/IE58791B1/en not_active IP Right Cessation
- 1985-11-13 LU LU86163A patent/LU86163A1/en unknown
- 1985-11-14 YU YU1786/85A patent/YU43689B/en unknown
- 1985-11-14 AR AR302267A patent/AR240931A1/en active
- 1985-11-15 GB GB08528226A patent/GB2167414B/en not_active Expired
- 1985-11-18 NL NL8503171A patent/NL192387C/en not_active IP Right Cessation
- 1985-11-18 FI FI854535A patent/FI84064C/en not_active IP Right Cessation
- 1985-11-19 CH CH4935/85A patent/CH659473A5/en not_active IP Right Cessation
- 1985-11-19 AT AT3371/85A patent/AT393268B/en not_active IP Right Cessation
- 1985-11-20 CS CS837885A patent/CS273610B2/en unknown
- 1985-11-20 CA CA000495804A patent/CA1337124C/en not_active Expired - Fee Related
- 1985-11-20 SE SE8505487A patent/SE465676B/en not_active IP Right Cessation
- 1985-11-20 DD DD85283042A patent/DD259191A1/en not_active IP Right Cessation
- 1985-11-21 PT PT81532A patent/PT81532B/en not_active IP Right Cessation
- 1985-11-21 ZA ZA858951A patent/ZA858951B/en unknown
- 1985-11-21 DK DK537785A patent/DK164865C/en not_active IP Right Cessation
- 1985-11-21 PL PL1985256374A patent/PL146890B1/en unknown
- 1985-11-21 NO NO854655A patent/NO160205C/en not_active IP Right Cessation
- 1985-11-21 ES ES549116A patent/ES8609311A1/en not_active Expired
- 1985-11-21 EG EG74085A patent/EG19424A/en active
- 1985-11-21 IT IT22932/85A patent/IT1190426B/en active
- 1985-11-21 SU SU853985401A patent/SU1436875A3/en active
- 1985-11-21 HU HU854448A patent/HU195503B/en not_active IP Right Cessation
- 1985-11-22 JP JP60261629A patent/JPS61143377A/en active Granted
- 1985-11-22 FR FR858517321A patent/FR2573427B1/en not_active Expired
- 1985-11-22 KR KR1019850008733A patent/KR870001020B1/en not_active Expired
- 1985-11-22 BE BE2/60850A patent/BE903693A/en not_active IP Right Cessation
- 1985-11-22 MX MX009022A patent/MX168415B/en unknown

Also Published As

Publication number	Publication date
HU195503B (en)	1988-05-30
FR2573427A1 (en)	1986-05-23
NL8503171A (en)	1986-06-16
CH659473A5 (en)	1987-01-30
BE903693A (en)	1986-05-22
EG19424A (en)	1995-02-28
CS837885A2 (en)	1990-08-14
SE8505487D0 (en)	1985-11-20
YU178685A (en)	1988-02-29
DK164865B (en)	1992-08-31
FI854535A0 (en)	1985-11-18
CA1337124C (en)	1995-09-26
ES8609311A1 (en)	1986-09-01
ES549116A0 (en)	1986-09-01
DE3442639A1 (en)	1986-05-22
IE852808L (en)	1986-05-22
CS273610B2 (en)	1991-03-12
DK164865C (en)	1993-01-18
AR240931A1 (en)	1991-03-27
SU1436875A3 (en)	1988-11-07
GB2167414A (en)	1986-05-29
PL146890B1 (en)	1989-03-31
SE465676B (en)	1991-10-14
KR860004056A (en)	1986-06-16
DK537785A (en)	1986-05-23
YU43689B (en)	1989-10-31
DK537785D0 (en)	1985-11-21
LU86163A1 (en)	1986-03-24
JPS61143377A (en)	1986-07-01
NO160205B (en)	1988-12-12
GB8528226D0 (en)	1985-12-18
NL192387B (en)	1997-03-03
DE3442639C2 (en)	1989-08-10
PL256374A1 (en)	1986-12-02
ZA858951B (en)	1986-08-27
FR2573427B1 (en)	1989-03-10
AT393268B (en)	1991-09-25
JPH0432073B2 (en)	1992-05-28
KR870001020B1 (en)	1987-05-23
HUT40114A (en)	1986-11-28
GB2167414B (en)	1989-01-11
FI84064C (en)	1991-10-10
SE8505487L (en)	1986-05-23
MX168415B (en)	1993-05-24
NL192387C (en)	1997-07-04
FI854535A7 (en)	1986-05-23
AR240931A2 (en)	1991-03-27
PT81532A (en)	1985-12-01
PT81532B (en)	1987-11-11
DD259191A1 (en)	1988-08-17
IE58791B1 (en)	1993-11-17
IT1190426B (en)	1988-02-16
IT8522932A0 (en)	1985-11-21
ATA337185A (en)	1991-02-15
NO854655L (en)	1986-05-23
FI84064B (en)	1991-06-28

Publication	Publication Date	Title
NO852124L (en)	1985-12-02	PROCEDURE FOR THE PREPARATION OF QUINOLO DERIVATIVES.
NO851400L (en)	1985-10-07	PROCEDURE FOR THE PREPARATION OF PHYSIOLOGICALLY ACTIVE POLYPEPTIDES.
NO852994L (en)	1986-01-31	PROCEDURE FOR THE PREPARATION OF GLUTARAMIDE DERIVATIVES.
NO167515C (en)	1991-11-13	PROCEDURE FOR THE PREPARATION OF BASIC NUTRIAL OILS.
NO170071C (en)	1992-09-09	PROCEDURE FOR THE PREPARATION OF CHLORODIOXIDE.
NO160206C (en)	1989-03-22	PROCEDURE FOR THE PREPARATION OF ISOSILYBIN-FREE SILIBININ.
NO165755C (en)	1991-04-10	PROCEDURE FOR THE PREPARATION OF TETRAFLUOROBENZOIC ACID.
NO884665D0 (en)	1988-10-20	PROCEDURE FOR THE PREPARATION OF 9-OH-ALCOXYGUANINE.
NO855067L (en)	1986-06-18	PROCEDURE FOR THE PREPARATION OF N-FORMYL-ALFA-ASPARTYL-PHENYLALANINE.
NO853066L (en)	1986-02-07	PROCEDURE FOR THE PREPARATION OF 3-CARBONYL-1-AMINOALKYL-1H-INDOLES.
NO160205C (en)	1989-03-22	PROCEDURE FOR THE PREPARATION OF SILIBINE INGREDIENTS.
NO165676C (en)	1991-03-20	PROCEDURE FOR THE PREPARATION OF PYRROLIDO DERIVATIVES.
NO852810L (en)	1986-01-14	PROCEDURE FOR THE PREPARATION OF FLUORALLYLAMINE DERIVATIVES.
NO166931C (en)	1991-09-18	PROCEDURE FOR THE PREPARATION OF CHLORODIOXIDE.
NO853172L (en)	1986-02-14	PROCEDURE FOR THE PREPARATION OF TIXOTROPIC DETERGENTS.
NO872809L (en)	1988-01-08	PROCEDURE FOR THE PREPARATION OF 5-AMINO-ALICYLIC ACID.
NO164417C (en)	1990-10-10	ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE IMINOTHIAZOLIDE INGREDIENTS.
NO165637C (en)	1991-03-13	PROCEDURE FOR THE PREPARATION OF ETHOXYLED LIGINITE.
NO872094D0 (en)	1987-05-19	PROCEDURE FOR THE PREPARATION OF DBH-INHIBITIVE COMPOUNDS.
NO165538C (en)	1991-02-27	PROCEDURE FOR THE PREPARATION OF CHLORODIOXIDE.
NO864386D0 (en)	1986-11-03	PROCEDURE FOR THE PREPARATION OF URETANES.
NO161353C (en)	1989-08-09	PROCEDURE FOR PREPARATION OF PASTILLS.
NO166709C (en)	1991-08-28	PROCEDURE FOR THE PREPARATION OF ACRYLAMIDS.
NO870543L (en)	1987-08-13	PROCEDURE FOR THE PREPARATION OF 4-ACETYLISOKINOLINONE COMPOUNDS.
NO161911C (en)	1989-10-11	PROCEDURE FOR THE PREPARATION OF SULPHONATES.

Legal Events

Date	Code	Title	Description
2002-07-08	MM1K	Lapsed by not paying the annual fees	Free format text: LAPSED IN MAY 2002