FI854035L - Farmaceutiska foereningar med antracyklinglykosider. - Google Patents

Farmaceutiska foereningar med antracyklinglykosider.

Info

Publication number: FI854035L
Authority: FI; Finland
Prior art keywords: antacacyclinglykosider; particulars; pharmaceutical; pharmaceutical particulars
Prior art date: 1984-10-22

Application number

FI854035A

Other languages

English (en)

Other versions

FI86252B (fi

FI86252C (fi

FI854035A0 (fi

Inventor

Gaetano Gatti

Diego Oldani

Carlo Confalonieri

Luciano Gambini

Original Assignee

Erba Farmitalia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-22

Filing date

1985-10-16

Publication date

1986-04-23

1985-10-16 Application filed by Erba Farmitalia filed Critical Erba Farmitalia

1985-10-16 Publication of FI854035A0 publication Critical patent/FI854035A0/fi

1986-04-23 Publication of FI854035L publication Critical patent/FI854035L/fi

1992-04-30 Publication of FI86252B publication Critical patent/FI86252B/fi

1992-08-10 Application granted granted Critical

1992-08-10 Publication of FI86252C publication Critical patent/FI86252C/fi

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oil, Petroleum & Natural Gas (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Saccharide Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

FI854035A 1984-10-22 1985-10-16 Foerfarande foer foerbaettring av en antracyklinglykosids upploesbarhet i en foer injektering laemplig loesningsmedelsblandning. FI86252C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB848426672A GB8426672D0 (en)	1984-10-22	1984-10-22	Pharmaceutical compositions
GB8426672		1984-10-22

Publications (4)

Publication Number	Publication Date
FI854035A0 FI854035A0 (fi)	1985-10-16
FI854035L true FI854035L (fi)	1986-04-23
FI86252B FI86252B (fi)	1992-04-30
FI86252C FI86252C (fi)	1992-08-10

Family

ID=10568553

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
FI853913A FI853913A7 (fi)	1984-10-22	1985-10-08	Farmaceutiska foereningar som antracyklinglykosider.
FI854035A FI86252C (fi)	1984-10-22	1985-10-16	Foerfarande foer foerbaettring av en antracyklinglykosids upploesbarhet i en foer injektering laemplig loesningsmedelsblandning.

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
FI853913A FI853913A7 (fi)	1984-10-22	1985-10-08	Farmaceutiska foereningar som antracyklinglykosider.

Country Status (35)

Country	Link
US (4)	US4675311A (fi)
JP (1)	JPH0611700B2 (fi)
KR (1)	KR920005813B1 (fi)
CN (1)	CN85107562B (fi)
AT (1)	AT401345B (fi)
AU (1)	AU572003B2 (fi)
BE (1)	BE903484A (fi)
BG (1)	BG60934B2 (fi)
CA (1)	CA1248453A (fi)
CH (1)	CH667594A5 (fi)
CS (1)	CS270421B2 (fi)
DE (1)	DE3536896C2 (fi)
DK (1)	DK165620C (fi)
ES (1)	ES8605374A1 (fi)
FI (2)	FI853913A7 (fi)
FR (1)	FR2571966B1 (fi)
GB (2)	GB8426672D0 (fi)
GR (1)	GR852549B (fi)
HK (1)	HK94390A (fi)
HU (1)	HU197988B (fi)
IE (1)	IE56992B1 (fi)
IL (1)	IL76732A (fi)
IT (1)	IT1186779B (fi)
MY (1)	MY103956A (fi)
NL (1)	NL191308C (fi)
NO (1)	NO170616C (fi)
NZ (1)	NZ213885A (fi)
PH (1)	PH23982A (fi)
PT (1)	PT81347B (fi)
RU (2)	RU1836088C (fi)
SE (1)	SE467520B (fi)
SG (1)	SG80290G (fi)
UA (2)	UA34419C2 (fi)
YU (1)	YU46160B (fi)
ZA (1)	ZA858033B (fi)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
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US5124318A (en) *	1985-08-02	1992-06-23	Farmitalia Carlo Erba S.R.L.	Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5977082A (en) *	1985-08-02	1999-11-02	Pharmacia & Upjohn Company	Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5124317A (en) *	1985-08-02	1992-06-23	Farmitalia Carlo Erba S.P.A.	Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
FR2607702B1 (fr) *	1986-12-05	1991-08-16	Erba Farmitalia	Solutions injectables pretes a l'emploi contenant un agent anti-tumeur du type anthracycline-glucoside
JP2603480B2 (ja) *	1987-08-05	1997-04-23	住友製薬株式会社	安定化されたアンスラサイクリン系製剤
DE3801178A1 (de) *	1988-01-18	1989-07-27	Hoechst Ag	Stabilisierte trockenzubereitung zytostatisch wirksamer anthracyclin-antibiotika und verfahren zu ihrer herstellung
US6300362B1 (en)	1990-07-25	2001-10-09	Novartis Ag (Formerly Sandoz Ltd.)	Stabilized pharmaceutical compositions comprising acid donors
NZ336381A (en)	1996-12-30	2000-11-24	Battelle Memorial Institute	Formulation and method for treating neoplasms by inhalation
US5942508A (en) *	1997-02-04	1999-08-24	Senju Pharmaceutical Co., Ltd.	Method for solubilizing pyridonecarboxylic acid solubilizer thereof and aqueous solution containing solubilized pyridonecarboxylic acid
RU2292216C2 (ru) *	2000-10-31	2007-01-27	Фарма Мар, С.А.	Кахалалид f
NZ534378A (en)	2002-02-22	2006-10-27	Schering Corp	Pharmaceutical formulations of antineoplastic agents, in particular temozolomide, processes of making and using the same
EP1474995B1 (en) *	2003-05-06	2012-11-14	Gumlink A/S	A method for producing chewing gum granules, a gum composition extruder and granulating system, and a chewing gum product
US20090099346A1 (en) *	2003-07-02	2009-04-16	Victor Matvienko	Thermally stable crystalline epirubicin hydrochloride
RU2341530C2 (ru) *	2003-07-02	2008-12-20	Солакс Корпорейшн	Термостойкий кристаллический гидрохлорид эпирубицина и способ его получения
ES2344899T3 (es) *	2003-09-25	2010-09-09	Astellas Pharma Inc.	Agente antitumoral que comprende un inhibidor de histona desacetilasa y un inhibidor de topoisomerasa ii.
RU2262923C2 (ru) *	2003-12-25	2005-10-27	Государственное образовательное учреждение высшего профессионального образования Курский государственный медицинский университет Министерства здравоохранения Российской Федерации	Иммобилизованная форма доксорубицина
US7388083B2 (en) *	2005-03-07	2008-06-17	Solux Corporation	Epimerization of 4′-C bond and modification of 14-CH3-(CO)-fragment in anthracyclin antibiotics
KR20070088447A (ko) *	2005-05-11	2007-08-29	시코르, 인크.	안정한 동결건조된 안트라사이클린 글리코시드
WO2007011743A2 (en)	2005-07-14	2007-01-25	Lipothera, Inc.	Sustained release enhanced lipolytic formulation for regional adipose tissue treatment
US9035032B2 (en) *	2005-12-13	2015-05-19	Solux Corporation	Method for preparing 4-demethyldaunorubicin
US8802830B2 (en) *	2005-12-20	2014-08-12	Solux Corporation	Synthesis of epirubicin from 13-dihydrodaunorubicine
US8148338B2 (en) *	2006-02-22	2012-04-03	Supratek Pharma Inc.	Doxorubicin formulations for anti-cancer use
US7470672B2 (en) *	2006-07-31	2008-12-30	Savvipharm Inc.	Compositions and methods of reducing tissue levels of drugs when given as orotate derivatives
KR20100029764A (ko) *	2007-05-16	2010-03-17	케이티비 투머포슝스케쉘샤프트 엠비에이치	저점성 안트라사이클린 제제
JP4456177B2 (ja)	2007-09-04	2010-04-28	明治製菓株式会社	注射剤、注射液および注射用キット製剤
MX2010004457A (es) *	2007-10-26	2010-05-03	Pfizer Prod Inc	Idarubicina para el tratamiento de linfoma en un perro.
US8357785B2 (en) *	2008-01-08	2013-01-22	Solux Corporation	Method of aralkylation of 4′-hydroxyl group of anthracylins
US9132084B2 (en)	2009-05-27	2015-09-15	Neothetics, Inc.	Methods for administration and formulations for the treatment of regional adipose tissue
KR20120113267A (ko) *	2010-01-15	2012-10-12	리쎄라 인코오포레이티드	동결건조 케이크 제제
EP2646012A4 (en)	2010-11-24	2014-12-10	Neothetics Inc	MONOTHERAPEUTIC FORMULATIONS OF SELECTIVE, LIPOPHILIC AND PROLONGED BETA AGONISTS AND METHODS OF COSMETIC TREATMENT OF SILHOUETTE ADPOSITY AND REINFORCEMENT
DE102011103751A1 (de)	2011-05-31	2012-12-06	Heraeus Precious Metals Gmbh & Co. Kg	Kristallisierung von Epirubicinhydrochlorid
DE102011111991A1 (de) *	2011-08-30	2013-02-28	Lead Discovery Center Gmbh	Neue Cyclosporin-Derivate
EP3915369A1 (en)	2012-12-13	2021-12-01	CytRx Corporation	Anthracycline formulations
CN113842392A (zh)	2013-06-05	2021-12-28	西特克斯公司	用于治疗癌症的细胞毒素剂

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YU33730B (en) *	1967-04-18	1978-02-28	Farmaceutici Italia	Process for preparing a novel antibiotic substance and salts thereof
US4039663A (en) *	1975-03-19	1977-08-02	Societa' Farmaceutici Italia S.P.A.	Daunomycins, process for their uses and intermediates
GB1506200A (en) *	1975-04-30	1978-04-05	Farmaceutici Italia	Glycosides
GB1567456A (en) *	1976-11-16	1980-05-14	Farmaceutici Italia	Daunomycin derivatives
US4177264A (en) *	1977-10-17	1979-12-04	Sri International	N-benzyl anthracyclines
GB2007645B (en) *	1977-10-17	1982-05-12	Stanford Res Inst Int	Benzyl anthracyclines and pharmaceutical compositions containing them
JPS563851A (en) *	1979-06-22	1981-01-16	Matsushita Electric Works Ltd	Fireplace in floor
JPS5756494A (en) *	1980-09-22	1982-04-05	Microbial Chem Res Found	New anthracyclin derivative
US4325947A (en) *	1981-05-12	1982-04-20	Farmitalia Carlo Erba S.P.A.	4-Demethoxy-4'-deoxydoxorubicin
IT1210476B (it) *	1981-05-28	1989-09-14	Erba Farmitalia	Antracicline.
US4438105A (en) *	1982-04-19	1984-03-20	Farmaitalia Carlo Erba S.P.A	4'-Iododerivatives of anthracycline glycosides
FI75834C (fi) *	1982-05-24	1988-08-08	Erba Farmitalia	Foerfarande foer framstaellning av antracyklinglykosidfoereningar.
US4464529A (en) *	1982-07-20	1984-08-07	Sri International	Analogues of morpholinyl daunorubicin and morpholinyl doxorubicin
CA1248944A (en) *	1982-09-28	1989-01-17	Gareth J. Thomas	Anthracycline glycosides
JPS5982395A (ja) *	1982-11-02	1984-05-12	Microbial Chem Res Found	アントラサイクリン化合物、その製造法およびその用途
GR79729B (fi) *	1982-12-20	1984-10-31	Univ Ohio State Res Found
JPS6092212A (ja) *	1983-10-26	1985-05-23	Kyowa Hakko Kogyo Co Ltd	ドキソルビシン塩の製剤
US4537882A (en) *	1984-05-10	1985-08-27	Ohio State University	4-Demethoxy-3'-desamino-2'-halo-anthracycline and pharmaceutical composition containing same

1984
- 1984-10-22 GB GB848426672A patent/GB8426672D0/en active Pending
1985
- 1985-10-03 ES ES547578A patent/ES8605374A1/es not_active Expired
- 1985-10-08 FI FI853913A patent/FI853913A7/fi not_active Application Discontinuation
- 1985-10-15 CN CN85107562A patent/CN85107562B/zh not_active Expired
- 1985-10-15 HU HU853988A patent/HU197988B/hu unknown
- 1985-10-16 DE DE3536896A patent/DE3536896C2/de not_active Expired - Lifetime
- 1985-10-16 US US06/788,158 patent/US4675311A/en not_active Expired - Lifetime
- 1985-10-16 IT IT22507/85A patent/IT1186779B/it active Protection Beyond IP Right Term
- 1985-10-16 FI FI854035A patent/FI86252C/fi not_active IP Right Cessation
- 1985-10-16 YU YU164485A patent/YU46160B/sh unknown
- 1985-10-17 AU AU48805/85A patent/AU572003B2/en not_active Expired
- 1985-10-17 IL IL76732A patent/IL76732A/xx not_active IP Right Cessation
- 1985-10-17 CH CH4476/85A patent/CH667594A5/de not_active IP Right Cessation
- 1985-10-17 JP JP60230055A patent/JPH0611700B2/ja not_active Expired - Lifetime
- 1985-10-18 UA UA5010680A patent/UA34419C2/uk unknown
- 1985-10-18 NZ NZ213885A patent/NZ213885A/en unknown
- 1985-10-18 GB GB08525709A patent/GB2165751B/en not_active Expired
- 1985-10-18 RU SU853964940A patent/RU1836088C/ru active
- 1985-10-18 AT AT0303285A patent/AT401345B/de not_active IP Right Cessation
- 1985-10-18 ZA ZA858033A patent/ZA858033B/xx unknown
- 1985-10-18 UA UA3964940A patent/UA19169A/uk unknown
- 1985-10-18 PH PH32947A patent/PH23982A/en unknown
- 1985-10-21 SE SE8504945A patent/SE467520B/sv not_active IP Right Cessation
- 1985-10-21 CA CA000493459A patent/CA1248453A/en not_active Expired
- 1985-10-21 BE BE0/215752A patent/BE903484A/fr not_active IP Right Cessation
- 1985-10-21 DK DK481585A patent/DK165620C/da not_active IP Right Cessation
- 1985-10-21 FR FR8515596A patent/FR2571966B1/fr not_active Expired
- 1985-10-21 KR KR1019850007740A patent/KR920005813B1/ko not_active Expired
- 1985-10-21 PT PT81347A patent/PT81347B/pt unknown
- 1985-10-21 NL NL8502869A patent/NL191308C/xx not_active IP Right Cessation
- 1985-10-21 IE IE2593/85A patent/IE56992B1/en not_active IP Right Cessation
- 1985-10-21 NO NO854194A patent/NO170616C/no not_active IP Right Cessation
- 1985-10-22 GR GR852549A patent/GR852549B/el unknown
- 1985-10-22 CS CS857565A patent/CS270421B2/cs not_active IP Right Cessation
1986
- 1986-08-06 US US06/893,613 patent/US4840938A/en not_active Expired - Lifetime
1988
- 1988-12-30 MY MYPI88001588A patent/MY103956A/en unknown
1990
- 1990-09-26 US US07/588,526 patent/US5091372A/en not_active Expired - Lifetime
- 1990-09-28 US US07/590,536 patent/US5091373A/en not_active Expired - Lifetime
- 1990-10-03 SG SG802/90A patent/SG80290G/en unknown
- 1990-11-15 HK HK943/90A patent/HK94390A/xx not_active IP Right Cessation
1992
- 1992-01-30 RU SU5010680A patent/RU2101018C1/ru active
1994
- 1994-02-23 BG BG098530A patent/BG60934B2/bg unknown

Also Published As

Publication number	Publication date
DK165620C (da)	1993-06-01
FI86252B (fi)	1992-04-30
AT401345B (de)	1996-08-26
NL191308B (nl)	1994-12-16
IT1186779B (it)	1987-12-16
NO854194L (no)	1986-04-23
NO170616B (no)	1992-08-03
FI86252C (fi)	1992-08-10
UA19169A (uk)	1997-12-25
CS756585A2 (en)	1989-11-14
NL191308C (nl)	1995-05-16
GB2165751A (en)	1986-04-23
SG80290G (en)	1990-11-23
UA34419C2 (uk)	2001-03-15
SE8504945L (sv)	1986-04-23
US4675311A (en)	1987-06-23
GB8525709D0 (en)	1985-11-20
HU197988B (en)	1989-07-28
GB8426672D0 (en)	1984-11-28
GR852549B (fi)	1986-02-24
IE852593L (en)	1986-04-22
IL76732A (en)	1989-07-31
FI854035A0 (fi)	1985-10-16
AU572003B2 (en)	1988-04-28
CS270421B2 (en)	1990-06-13
CN85107562A (zh)	1986-07-23
YU46160B (sh)	1993-05-28
FR2571966A1 (fr)	1986-04-25
AU4880585A (en)	1986-05-01
KR920005813B1 (ko)	1992-07-20
US4840938A (en)	1989-06-20
YU164485A (en)	1987-10-31
FI853913A7 (fi)	1986-04-23
PT81347A (en)	1985-11-01
RU2101018C1 (ru)	1998-01-10
NO170616C (no)	1992-11-11
NZ213885A (en)	1988-05-30
US5091373A (en)	1992-02-25
MY103956A (en)	1993-10-30
JPH0611700B2 (ja)	1994-02-16
DK165620B (da)	1992-12-28
FI853913A0 (fi)	1985-10-08
SE467520B (sv)	1992-08-03
ZA858033B (en)	1986-06-25
ES547578A0 (es)	1986-03-16
DE3536896A1 (de)	1986-04-24
DK481585D0 (da)	1985-10-21
PH23982A (en)	1990-02-09
ES8605374A1 (es)	1986-03-16
US5091372A (en)	1992-02-25
NL8502869A (nl)	1986-05-16
BG60934B2 (bg)	1996-06-28
DE3536896C2 (de)	1996-11-14
CA1248453A (en)	1989-01-10
IL76732A0 (en)	1986-02-28
ATA303285A (de)	1996-01-15
CH667594A5 (de)	1988-10-31
RU1836088C (ru)	1993-08-23
HK94390A (en)	1990-11-23
PT81347B (pt)	1987-11-11
GB2165751B (en)	1988-08-17
CN85107562B (zh)	1988-06-01
BE903484A (fr)	1986-04-21
KR860003014A (ko)	1986-05-19
IT8522507A0 (it)	1985-10-16
FR2571966B1 (fr)	1988-04-15
DK481585A (da)	1986-04-23
JPS61246129A (ja)	1986-11-01
HUT40759A (en)	1987-02-27
SE8504945D0 (sv)	1985-10-21
IE56992B1 (en)	1992-02-26

Publication	Publication Date	Title
FI854035A0 (fi)	1985-10-16	Farmaceutiska foereningar med antracyklinglykosider.
MX9202933A (es)	1992-06-30	Derivados de tiazolidindiona.
FI863429A0 (fi)	1986-08-25	Tablett med styrd frigivning av aktivaemne.
FI862907A0 (fi)	1986-07-10	Foerfarande foer framstaellning av fenyletanolamintetraliner med lypolytisk aktivitet.
FI863077A0 (fi)	1986-07-28	Farmaceutisk dosenhet.
FI860447L (fi)	1986-08-02	Foerfarande foer behandling av luftpermeabla underlag med skum.
FI854573A0 (fi)	1985-11-20	Farmaceutiska kapslar med foerdroejd frigoering.
FI862544A7 (fi)	1986-12-18	Kretssystem foer modifiering av dynamisk baervidd med anvaendning av verkningssubstitutions- och superponeringsteknik.
FI861186A0 (fi)	1986-03-20	Foerbaettringar av anordningar foer framstaellning av mineralfibrer med hjaelp av centrifugalhjul.
FI861218L (fi)	1986-09-23	Foerfarande foer behandling av vaott papper med skum.
FI862393L (fi)	1986-12-19	Silanordning med anordning foer reduktion av rejekt.
IT1209615B (it)	1989-08-30	Composizione farmaceutica
DK288686D0 (da)	1986-06-19	Farmaceutiske praeparater
FI852658L (fi)	1986-01-07	Farmaceutiska aemnen.
MX9203229A (es)	1992-07-01	Derivados de lankacidina.
FI852772A0 (fi)	1985-07-15	Formsten.
FI854670L (fi)	1987-05-27	Saett foer framstaellande av borstelement med plaststomme.
FI862338A7 (fi)	1986-12-04	Foerfarande foer vaord av haor med trialkylaettiksyraamider.
FI863883A0 (fi)	1986-09-25	Anordning foer tillslutning av flaskhals.
DK453785D0 (da)	1985-10-04	Laegemiddel med grf-virkning
FI853523A0 (fi)	1985-09-13	Foerfarande foer utfoering av immunobestaemningar med hjaelp av enzymstaempel.
FI852876A0 (fi)	1985-07-24	Anordning foer undervattensarbete.
FI862472L (fi)	1987-03-01	Ampullhaollare med en luftoeppning foer reducering av statisk elektricitet.
RO90578A2 (ro)	1986-12-10	Produs medicamentos fitoterapeutic hepatoprotector
SE8404468D0 (sv)	1984-09-06	Farmaceutisk beredning

Legal Events

Date	Code	Title	Description
1995-11-27	PC	Transfer of assignment of patent	Owner name: PHARMACIA & UPJOHN S.P.A.
1996-11-29	PC	Transfer of assignment of patent	Owner name: PHARMACIA & UPJOHN S.P.A.
2004-08-31	FG	Patent granted	Owner name: PHARMACIA ITALIA S.P.A.
2005-11-15	MA	Patent expired