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ES2058047T3 - Resolucion de acido arilalcanoico. - Google Patents

Resolucion de acido arilalcanoico.

Info

Publication number
ES2058047T3
ES2058047T3 ES92918204T ES92918204T ES2058047T3 ES 2058047 T3 ES2058047 T3 ES 2058047T3 ES 92918204 T ES92918204 T ES 92918204T ES 92918204 T ES92918204 T ES 92918204T ES 2058047 T3 ES2058047 T3 ES 2058047T3
Authority
ES
Spain
Prior art keywords
arilalcanoic
resolution
acid
rethemic
ketoprophene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92918204T
Other languages
English (en)
Other versions
ES2058047T1 (es
Inventor
Christopher Thomas Evans
Richard Anthony Wisdom
Peter Joseph Stabler
Germano Carganico
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Menarini SA
Original Assignee
Laboratorios Menarini SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Menarini SA filed Critical Laboratorios Menarini SA
Publication of ES2058047T1 publication Critical patent/ES2058047T1/es
Application granted granted Critical
Publication of ES2058047T3 publication Critical patent/ES2058047T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE PRODUCEN ACIDOS ARILOALCANOICOS POR BIOTRANSFORMACION USANDO MICROORGANISMOS ADECUADOS Y, EN PARTICULAR, (S)-QUETOPROFENO DE PUREZA SUPERIOR AL 95% A PARTIR DE ESTER DE ETILO QUETOPROFENO RACEMICO.
ES92918204T 1991-08-22 1992-08-19 Resolucion de acido arilalcanoico. Expired - Lifetime ES2058047T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919118149A GB9118149D0 (en) 1991-08-22 1991-08-22 Araylalkanoic acid resolution

Publications (2)

Publication Number Publication Date
ES2058047T1 ES2058047T1 (es) 1994-11-01
ES2058047T3 true ES2058047T3 (es) 1998-01-16

Family

ID=10700381

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92918204T Expired - Lifetime ES2058047T3 (es) 1991-08-22 1992-08-19 Resolucion de acido arilalcanoico.

Country Status (22)

Country Link
US (1) US5516690A (es)
EP (1) EP0599967B1 (es)
JP (1) JP3174328B2 (es)
KR (1) KR100240696B1 (es)
AT (1) ATE161053T1 (es)
AU (1) AU662556B2 (es)
BG (1) BG62056B1 (es)
CA (1) CA2116003C (es)
CZ (1) CZ283141B6 (es)
DE (2) DE69223516T2 (es)
DK (1) DK0599967T3 (es)
ES (1) ES2058047T3 (es)
FI (1) FI103807B (es)
GB (1) GB9118149D0 (es)
GR (2) GR940300068T1 (es)
HU (1) HU213748B (es)
NO (1) NO315750B1 (es)
RO (1) RO115970B1 (es)
RU (1) RU2119955C1 (es)
SK (1) SK280179B6 (es)
UA (1) UA27817C2 (es)
WO (1) WO1993004189A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9304351D0 (en) * 1993-03-03 1993-04-21 Chiros Ltd Arylalkanoic acid resolution and microorganisms for use therein
US5912164A (en) * 1993-03-03 1999-06-15 Laboratorios Menarini S.A. Stereoselective hydrolysis of chiral carboxylic acid esters using esterase from ophiostoma or ceratocystis
GB9304256D0 (en) * 1993-03-03 1993-04-21 Chiros Ltd Arylalkanoic acid resolution
US6242243B1 (en) * 1998-03-30 2001-06-05 Council Of Scientific & Industrial Research Trichosporon sp RRLY-15 (DSM 11829) and its use to prepare S(+)-6-methoxy-methyl-2-naphthalene acetic acid
US20030059903A1 (en) * 2001-04-03 2003-03-27 Degussa Ag Process for the production of L-amino acids using strains of the family enterobacteriaceae that contain an attenuated aceA gene
US7223582B2 (en) * 2002-01-17 2007-05-29 Korea Research Institute Of Bioscience And Biotechnology Esterase, its DNA, its overexpression and production of optically active aryl propionic acids using the same
RU2290758C1 (ru) * 2005-04-25 2006-12-27 Федеральное государственное унитарное предприятие "Воронежский научно-исследовательский институт связи" Способ передачи дискретной информации в радиолинии со скачкообразной перестройкой рабочей частоты
RU2364442C1 (ru) * 2008-06-30 2009-08-20 Государственное образовательное учреждение высшего профессионального образования "Тверской государственный технический университет" Способ приготовления модифицированного платинового катализатора для энантиоселективного гидрирования сложных эфиров альфа-кетокарбоновых кислот
CN105848638A (zh) * 2013-12-16 2016-08-10 硕腾服务有限责任公司 长效酮洛芬组合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0197474B1 (en) * 1985-04-01 1991-07-10 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for preparing optically active indoline-2-carboxylic acid
US5322791A (en) * 1985-12-20 1994-06-21 Wisconsin Alumni Research Foundation Process for preparing (S)-α-methylarylacetic acids
KR880007428A (ko) * 1985-12-20 1988-08-27 존 알. 파이크 (S)-α-메틸 아릴 아세트산의 제조방법
US4857469A (en) * 1987-04-09 1989-08-15 Toyo Jozo Co., Ltd. Process for preparing optically active mercapto compound
US5108916A (en) * 1989-06-05 1992-04-28 Rhone-Poulenc Rorer, S.A. Process for stereoselectively hydrolyzing, transesterifying or esterifying with immobilized isozyme of lipase from candida rugosa
WO1991013163A1 (en) * 1990-02-26 1991-09-05 Rhone-Poulenc Inc. Stereospecific resolution by hydrolysis of esters of 2-arylpropionic acids by liver enzymes

Also Published As

Publication number Publication date
KR100240696B1 (ko) 2000-01-15
FI103807B1 (fi) 1999-09-30
JPH06510182A (ja) 1994-11-17
DK0599967T3 (da) 1998-08-24
BG98484A (bg) 1994-01-03
NO940570L (no) 1994-02-18
CA2116003A1 (en) 1993-03-04
AU662556B2 (en) 1995-09-07
RU2119955C1 (ru) 1998-10-10
NO315750B1 (no) 2003-10-20
RU94015601A (ru) 1996-07-10
CZ36494A3 (en) 1994-08-17
ATE161053T1 (de) 1997-12-15
HU213748B (en) 1997-09-29
GR940300068T1 (en) 1994-10-31
CA2116003C (en) 2004-11-16
SK280179B6 (sk) 1999-09-10
US5516690A (en) 1996-05-14
EP0599967A1 (en) 1994-06-08
FI940792A0 (fi) 1994-02-18
RO115970B1 (ro) 2000-08-30
UA27817C2 (uk) 2000-10-16
CZ283141B6 (cs) 1998-01-14
SK17694A3 (en) 1995-02-08
DE599967T1 (de) 1995-06-14
DE69223516T2 (de) 1998-05-20
FI103807B (fi) 1999-09-30
NO940570D0 (no) 1994-02-18
AU2468592A (en) 1993-03-16
HU9400462D0 (en) 1994-06-28
GR3026303T3 (en) 1998-06-30
BG62056B1 (bg) 1999-01-29
WO1993004189A1 (en) 1993-03-04
EP0599967B1 (en) 1997-12-10
DE69223516D1 (de) 1998-01-22
GB9118149D0 (en) 1991-10-09
FI940792L (fi) 1994-02-18
HUT69778A (en) 1995-09-28
JP3174328B2 (ja) 2001-06-11
ES2058047T1 (es) 1994-11-01

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