DK3638370T3 - Behandling af migræne med acetyl-leucin - Google Patents

Behandling af migræne med acetyl-leucin Download PDF

Info

Publication number: DK3638370T3
Authority: DK; Denmark
Prior art keywords: migrain; leucin; acetyl; treatment
Prior art date: 2017-06-14

Application number

DK18749124.6T

Other languages

English (en)

Inventor

Michael Strupp

Mallory Factor

Original Assignee

Intrabio Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2017-06-14

Filing date

2018-06-25

Publication date

2021-01-25

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=59358204&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3638370(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2018-06-25 Application filed by Intrabio Ltd filed Critical Intrabio Ltd

2021-01-25 Application granted granted Critical

2021-01-25 Publication of DK3638370T3 publication Critical patent/DK3638370T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK18749124.6T 2017-06-14 2018-06-25 Behandling af migræne med acetyl-leucin DK3638370T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB1709459.0A GB201709459D0 (en)	2017-06-14	2017-06-14	Treatment for migraine
PCT/IB2018/054676 WO2018229738A1 (en)	2017-06-14	2018-06-25	Treatment for migraine

Publications (1)

Publication Number	Publication Date
DK3638370T3 true DK3638370T3 (da)	2021-01-25

Family

ID=59358204

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK18749124.6T DK3638370T3 (da)	2017-06-14	2018-06-25	Behandling af migræne med acetyl-leucin

Country Status (26)

Country	Link
US (1)	US11471434B2 (da)
EP (1)	EP3638370B1 (da)
JP (1)	JP7130739B2 (da)
KR (1)	KR102594130B1 (da)
CN (1)	CN111093772B (da)
AU (1)	AU2018284330B2 (da)
CA (1)	CA3067321A1 (da)
CY (1)	CY1123860T1 (da)
DK (1)	DK3638370T3 (da)
ES (1)	ES2847169T3 (da)
GB (1)	GB201709459D0 (da)
HR (1)	HRP20210108T1 (da)
HU (1)	HUE053089T2 (da)
IL (1)	IL271211B2 (da)
LT (1)	LT3638370T (da)
MA (1)	MA49396B1 (da)
MD (1)	MD3638370T2 (da)
MX (1)	MX387909B (da)
PL (1)	PL3638370T3 (da)
PT (1)	PT3638370T (da)
RS (1)	RS61481B1 (da)
SG (1)	SG11201912146RA (da)
SI (1)	SI3638370T1 (da)
SM (1)	SMT202100037T1 (da)
WO (1)	WO2018229738A1 (da)
ZA (1)	ZA201908087B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2983441T3 (es) *	2018-02-15	2024-10-23	Intrabio Ltd	Acetil-leucina para su uso en el tratamiento de síndrome de las piernas inquietas
CN113348018B (zh)	2018-12-06	2025-04-01	内在生物技术有限公司	乙酰基-亮氨酸的氘代类似物

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE8701662L (sv) *	1987-04-22	1988-10-23	Gelder Nico M Van	Saett och medel foer att behandla neurologiska sjukdomar, exempelvis migraen genom paaverkan av nervcellerna
US20040127501A1 (en) *	2002-09-24	2004-07-01	Zhengming Chen	Therapeutic agents useful for treating pain
US20060063827A1 (en)	2004-09-23	2006-03-23	Yu Ruey J	Systemic administration of therapeutic amino acids and N-acetylamino acids
TWI287010B (en) *	2003-06-12	2007-09-21	Euro Celtique Sa	Therapeutic agents useful for treating pain
PT1641775E (pt) *	2003-07-03	2009-04-23	Euro Celtique Sa	Derivados de 2-piridina-alcino úteis para o tratamento da dor
DE602004021206D1 (de) *	2003-07-24	2009-07-02	Euro Celtique Sa	Zur Behandlung oder Vorbeugung von Schmerzen geeignete Heteroaryl-Tetrahydropiperidyl-Verbindungen
ES2317052T3 (es) *	2003-09-22	2009-04-16	Euro-Celtique S.A.	Agentes terapeuticos utiles para el tratamiento del dolor.
PL1664041T3 (pl) *	2003-09-22	2008-12-31	Euro Celtique Sa	Przydatne do leczenia bólu związki fenylowo-karboksyamidowe
NZ548169A (en) *	2003-12-30	2009-04-30	Euro Celtique Sa	Piperazines useful for treating pain
FR2905600B1 (fr) *	2006-09-13	2010-01-15	Pf Medicament	Traitement des vertiges par l'acetyl-l-leucine.
TN2010000251A1 (fr)	2010-06-03	2011-11-11	Rekik Raouf	N-acetyl-dl-leucine medicament neuro et retino protecteur
EP2585446A4 (en) *	2010-06-22	2013-12-25	Shionogi & Co	COMPOUNDS HAVING ANTAGONIST ACTIVITY OF TRPV1 AND USES THEREOF
DK2588130T3 (da)	2010-06-25	2016-10-24	Shire Human Genetic Therapies	Cns-afgivelse af terapeutiske midler
ES2732818T3 (es) *	2010-11-09	2019-11-26	Mannkind Corp	Composición que comprende un agonista de receptores de serotonina y una dicetopiperazina para tratar migrañas
US9394293B2 (en) *	2011-08-10	2016-07-19	Purdue Pharma L.P.	TRPV1 antagonists including dihydroxy substituent and uses thereof
EP4501406A3 (en)	2016-04-19	2025-03-26	IntraBio Ltd	Acetyl-leucine or a pharmaceutically acceptable salt thereof for improved mobility and cognitive function
LT3416631T (lt)	2016-08-11	2019-08-26	Intrabio Ltd	Terapiniai agentai, skirti neurodegeneracinių ligų gydymui
TN2019000032A1 (en)	2016-08-11	2020-07-15	Intrabio Ltd	Pharmaceutical compositions and uses directed to lysosomal storage disorders
ES2950452T3 (es)	2017-03-28	2023-10-10	Intrabio Ltd	Betahistina, o una sal farmacéuticamente aceptable de la misma, e inhibidor de monoamina oxidasa, para su uso en el tratamiento o la prevención de uno o más síntomas de vértigo en un sujeto
US12458614B2 (en)	2017-10-18	2025-11-04	Intrabio Ltd	Therapeutic agents for improved mobility and cognitive function and for treating neurodegenerative diseases and lysosomal storage disorders
CN111542314B (zh)	2017-10-18	2023-11-24	内在生物技术有限公司	神经退行性疾病的治疗剂
ES2983441T3 (es)	2018-02-15	2024-10-23	Intrabio Ltd	Acetil-leucina para su uso en el tratamiento de síndrome de las piernas inquietas
CN113348018B (zh)	2018-12-06	2025-04-01	内在生物技术有限公司	乙酰基-亮氨酸的氘代类似物
IL321899A (en)	2019-03-02	2025-09-01	Intrabio Ltd	Leucine, acetyl leucine and related analogs for the treatment of disease
EP4650003A2 (en)	2019-06-28	2025-11-19	IntraBio Ltd	Combination therapy with acetyl-leucine and miglustat for treating a lysosomal storage disease
WO2021144720A1 (en)	2020-01-13	2021-07-22	Intrabio Ltd	Treatment of late-onset neurodegenerative diseases in heterozygous npc1 gene mutation carriers

2017
- 2017-06-14 GB GBGB1709459.0A patent/GB201709459D0/en not_active Ceased
2018
- 2018-06-25 IL IL271211A patent/IL271211B2/en unknown
- 2018-06-25 MD MDE20200433T patent/MD3638370T2/ro unknown
- 2018-06-25 EP EP18749124.6A patent/EP3638370B1/en active Active
- 2018-06-25 DK DK18749124.6T patent/DK3638370T3/da active
- 2018-06-25 CN CN201880039532.2A patent/CN111093772B/zh active Active
- 2018-06-25 SI SI201830195T patent/SI3638370T1/sl unknown
- 2018-06-25 MX MX2019014784A patent/MX387909B/es unknown
- 2018-06-25 KR KR1020197038730A patent/KR102594130B1/ko active Active
- 2018-06-25 PL PL18749124T patent/PL3638370T3/pl unknown
- 2018-06-25 AU AU2018284330A patent/AU2018284330B2/en active Active
- 2018-06-25 SM SM20210037T patent/SMT202100037T1/it unknown
- 2018-06-25 LT LTEP18749124.6T patent/LT3638370T/lt unknown
- 2018-06-25 MA MA49396A patent/MA49396B1/fr unknown
- 2018-06-25 PT PT187491246T patent/PT3638370T/pt unknown
- 2018-06-25 US US16/622,785 patent/US11471434B2/en active Active
- 2018-06-25 WO PCT/IB2018/054676 patent/WO2018229738A1/en not_active Ceased
- 2018-06-25 ES ES18749124T patent/ES2847169T3/es active Active
- 2018-06-25 CA CA3067321A patent/CA3067321A1/en active Pending
- 2018-06-25 HR HRP20210108TT patent/HRP20210108T1/hr unknown
- 2018-06-25 RS RS20210046A patent/RS61481B1/sr unknown
- 2018-06-25 HU HUE18749124A patent/HUE053089T2/hu unknown
- 2018-06-25 JP JP2020519196A patent/JP7130739B2/ja active Active
- 2018-06-25 SG SG11201912146RA patent/SG11201912146RA/en unknown
2019
- 2019-12-05 ZA ZA2019/08087A patent/ZA201908087B/en unknown
2021
- 2021-01-18 CY CY20211100033T patent/CY1123860T1/el unknown

Also Published As

Publication number	Publication date
IL271211B2 (en)	2024-01-01
GB201709459D0 (en)	2017-07-26
JP2020526575A (ja)	2020-08-31
WO2018229738A1 (en)	2018-12-20
IL271211A (en)	2020-01-30
MA49396B1 (fr)	2021-03-31
RS61481B1 (sr)	2021-03-31
PL3638370T3 (pl)	2021-05-17
SI3638370T1 (sl)	2021-04-30
PT3638370T (pt)	2021-01-26
AU2018284330B2 (en)	2024-03-14
BR112019026660A2 (pt)	2020-07-14
MD3638370T2 (ro)	2021-04-30
IL271211B1 (en)	2023-09-01
EP3638370B1 (en)	2020-11-11
LT3638370T (lt)	2021-03-25
HUE053089T2 (hu)	2021-06-28
MX2019014784A (es)	2021-11-16
CA3067321A1 (en)	2018-12-20
AU2018284330A1 (en)	2020-01-02
CN111093772A (zh)	2020-05-01
RU2020100475A3 (da)	2021-10-22
SMT202100037T1 (it)	2021-03-15
US11471434B2 (en)	2022-10-18
JP7130739B2 (ja)	2022-09-05
KR20210013518A (ko)	2021-02-04
CY1123860T1 (el)	2022-05-27
EP3638370A1 (en)	2020-04-22
SG11201912146RA (en)	2020-01-30
CN111093772B (zh)	2023-11-03
ZA201908087B (en)	2024-11-27
ES2847169T3 (es)	2021-08-02
HRP20210108T1 (hr)	2021-03-19
RU2020100475A (ru)	2021-07-14
US20200253905A1 (en)	2020-08-13
KR102594130B1 (ko)	2023-10-24
MA49396A (fr)	2020-04-22
MX387909B (es)	2025-03-19

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